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The map label for this gene is puuP [H]

Identifier: 77460777

GI number: 77460777

Start: 5139458

End: 5140783

Strand: Reverse

Name: puuP [H]

Synonym: Pfl01_4556

Alternate gene names: 77460777

Gene position: 5140783-5139458 (Counterclockwise)

Preceding gene: 77460778

Following gene: 77460771

Centisome position: 79.85

GC content: 61.69

Gene sequence:

>1326_bases
ATGGCTCGTTTGCAACGCACCCTTTCACTAGGGTCGGTGGTGCTGTTCGGCATCGCCTACATGACGCCGATCATTGTCCT
CGGCACGTTCGGCATCCTCGCCCAGTCCACCGCCGGCATGGTGCCCGCCGCGTATCTGGCGGCGCTGGTGGCGATGTTTT
TCACCGCCATGAGCTACGGTCGCATGGCCGCTGCGTTTCCGGTGGCCGGCTCGGCCTACAGCTACGTGCGCAAGGCCATC
AGCCCGAAACTCGGCTTCATCGCCGGTTGGGCGGTGCTGCTCGATTATCTGTTTCTGCCGATGGCGATCTGGCTGATCGG
CGCCGCGTACCTCGCGTCGGCCTTCCCGTCGATCCCGCAGTGGATCTGGGTGCTGGCGTTCATCGGCATCACCAGCGCGA
TCAACATCATCGGCCTGAAGCTGGCCAACGGCATCAACGCCTTGCTGATGCTGGTGCAGTTCCTGGTGCTGATCGCCTTC
GTCGGGCTGTGCGTGCATTACGTCGGCGGCGATGCCAGCCAGCCGCTGTGGTCGATCAAACCGTTCTTCAATGGCGACAT
GCAAATGCCGCTGATCATGAGCGGCGCGGCCATCGCTTGCTATTCGTTCCTCGGTTTTGATGCGGTCAGCACCCTCACCG
AAGAAACCCGCGATCCACGTCGCACCATCCCTCGGGCAATCATGTTGATCACCCTGATCGGCGGGCTGATTTTCGTCGGC
GTCTCGTACTTCGTGCAGATCGCCCATCCTTCGTTCCAGTTCGACAGCGTCGACTCGGCGGCCTACGAGATTGCGCGCAA
CATTGGCGGTGATCTGTTCGTGTCGATCTTCCTGATCGGCCTGATCGTCGGTCAGTTCGCCTCGGGTCTGTCGGCGCAGG
CCAGCGGTTCGCGTTTGTTGTTCGCGATGGGCCGTGACGGTGTGCTGCCCAAGTCATTCTTCGGCACCTTGCACGAGCGC
TTCGGCACGCCGGTCAACAGCATCCTGCTGTGTGCGGTGGTGGCCTTGCTGGCGCTGAAACTAGACGTGACCACCTCGAC
CTCGTTCATCAACTTCGGCGCGTTTCTGGCGTTCAGTCTGGTCAACCTGTCGGTGATTTTTCACTACTGGATCGGCGGCG
AGAAAAAAGGCCTGCGCGAGTTGATCCTGTTCCTGATCTTCCCGTTCATCGGCCTGGCGGCGGACTTGTGGCTGATGGTC
AGCCTCGATCACCTGGCGGTGTATCTGGGCCTGAGCTGGCTGGCGATTGGCGTGGTGTACCTGGCGGTGCTTACGGGTGG
CTTCCGCCGGCAGCCGCCGGAGATGGATTTCCAGGAAGCCGCCTGA

Upstream 100 bases:

>100_bases
CAACACATCTGTTTGACCCAAGAACAACAACGCAACACCCGAAACATTCGCCGAACTCGGCCTCTGCCATAAATCCAATA
AAATCCGGAGTAAGTCGCCC

Downstream 100 bases:

>100_bases
CCCGGCATCAGGCCGCCGGGCGGGTCTGGCGTAACGGCAACTGCACGCGGAACGTCGTGCCGGCGCCCAACGTGCTGCGC
ACGGAAATATCGCCGCCGTG

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MARLQRTLSLGSVVLFGIAYMTPIIVLGTFGILAQSTAGMVPAAYLAALVAMFFTAMSYGRMAAAFPVAGSAYSYVRKAI
SPKLGFIAGWAVLLDYLFLPMAIWLIGAAYLASAFPSIPQWIWVLAFIGITSAINIIGLKLANGINALLMLVQFLVLIAF
VGLCVHYVGGDASQPLWSIKPFFNGDMQMPLIMSGAAIACYSFLGFDAVSTLTEETRDPRRTIPRAIMLITLIGGLIFVG
VSYFVQIAHPSFQFDSVDSAAYEIARNIGGDLFVSIFLIGLIVGQFASGLSAQASGSRLLFAMGRDGVLPKSFFGTLHER
FGTPVNSILLCAVVALLALKLDVTTSTSFINFGAFLAFSLVNLSVIFHYWIGGEKKGLRELILFLIFPFIGLAADLWLMV
SLDHLAVYLGLSWLAIGVVYLAVLTGGFRRQPPEMDFQEAA

Sequences:

>Translated_441_residues
MARLQRTLSLGSVVLFGIAYMTPIIVLGTFGILAQSTAGMVPAAYLAALVAMFFTAMSYGRMAAAFPVAGSAYSYVRKAI
SPKLGFIAGWAVLLDYLFLPMAIWLIGAAYLASAFPSIPQWIWVLAFIGITSAINIIGLKLANGINALLMLVQFLVLIAF
VGLCVHYVGGDASQPLWSIKPFFNGDMQMPLIMSGAAIACYSFLGFDAVSTLTEETRDPRRTIPRAIMLITLIGGLIFVG
VSYFVQIAHPSFQFDSVDSAAYEIARNIGGDLFVSIFLIGLIVGQFASGLSAQASGSRLLFAMGRDGVLPKSFFGTLHER
FGTPVNSILLCAVVALLALKLDVTTSTSFINFGAFLAFSLVNLSVIFHYWIGGEKKGLRELILFLIFPFIGLAADLWLMV
SLDHLAVYLGLSWLAIGVVYLAVLTGGFRRQPPEMDFQEAA
>Mature_440_residues
ARLQRTLSLGSVVLFGIAYMTPIIVLGTFGILAQSTAGMVPAAYLAALVAMFFTAMSYGRMAAAFPVAGSAYSYVRKAIS
PKLGFIAGWAVLLDYLFLPMAIWLIGAAYLASAFPSIPQWIWVLAFIGITSAINIIGLKLANGINALLMLVQFLVLIAFV
GLCVHYVGGDASQPLWSIKPFFNGDMQMPLIMSGAAIACYSFLGFDAVSTLTEETRDPRRTIPRAIMLITLIGGLIFVGV
SYFVQIAHPSFQFDSVDSAAYEIARNIGGDLFVSIFLIGLIVGQFASGLSAQASGSRLLFAMGRDGVLPKSFFGTLHERF
GTPVNSILLCAVVALLALKLDVTTSTSFINFGAFLAFSLVNLSVIFHYWIGGEKKGLRELILFLIFPFIGLAADLWLMVS
LDHLAVYLGLSWLAIGVVYLAVLTGGFRRQPPEMDFQEAA

Specific function: Imports putrescine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=409, Percent_Identity=26.4058679706601, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI258645169, Length=425, Percent_Identity=24.7058823529412, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI258614005, Length=418, Percent_Identity=23.6842105263158, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI258614003, Length=425, Percent_Identity=24, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI110347453, Length=392, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI181337167, Length=369, Percent_Identity=25.7452574525745, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI114326544, Length=194, Percent_Identity=27.8350515463918, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI114326550, Length=194, Percent_Identity=27.8350515463918, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI186910308, Length=350, Percent_Identity=26.2857142857143, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI186910306, Length=350, Percent_Identity=26.2857142857143, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI186910304, Length=350, Percent_Identity=26.2857142857143, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081869, Length=434, Percent_Identity=43.778801843318, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI87082023, Length=437, Percent_Identity=42.3340961098398, Blast_Score=344, Evalue=8e-96,
Organism=Escherichia coli, GI1786789, Length=308, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786602, Length=292, Percent_Identity=25, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786302, Length=324, Percent_Identity=24.0740740740741, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788480, Length=326, Percent_Identity=25.1533742331288, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081708, Length=393, Percent_Identity=23.4096692111959, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081915, Length=303, Percent_Identity=23.7623762376238, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790653, Length=278, Percent_Identity=23.3812949640288, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17533459, Length=401, Percent_Identity=27.1820448877805, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17532491, Length=396, Percent_Identity=26.2626262626263, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531343, Length=397, Percent_Identity=23.4256926952141, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221512776, Length=411, Percent_Identity=23.6009732360097, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24666159, Length=411, Percent_Identity=23.6009732360097, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281366235, Length=411, Percent_Identity=26.0340632603406, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI116007820, Length=411, Percent_Identity=26.0340632603406, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667468, Length=388, Percent_Identity=25.7731958762887, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24668806, Length=404, Percent_Identity=25.4950495049505, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21356285, Length=404, Percent_Identity=25.4950495049505, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24668802, Length=404, Percent_Identity=25.4950495049505, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI116007818, Length=411, Percent_Identity=25.7907542579075, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI85725152, Length=411, Percent_Identity=25.7907542579075, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 47533; Mature: 47402

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
ARLQRTLSLGSVVLFGIAYMTPIIVLGTFGILAQSTAGMVPAAYLAALVAMFFTAMSYG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
RMAAAFPVAGSAYSYVRKAISPKLGFIAGWAVLLDYLFLPMAIWLIGAAYLASAFPSIPQ
CHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
WIWVLAFIGITSAINIIGLKLANGINALLMLVQFLVLIAFVGLCVHYVGGDASQPLWSIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECC
PFFNGDMQMPLIMSGAAIACYSFLGFDAVSTLTEETRDPRRTIPRAIMLITLIGGLIFVG
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
VSYFVQIAHPSFQFDSVDSAAYEIARNIGGDLFVSIFLIGLIVGQFASGLSAQASGSRLL
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
FAMGRDGVLPKSFFGTLHERFGTPVNSILLCAVVALLALKLDVTTSTSFINFGAFLAFSL
EEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VNLSVIFHYWIGGEKKGLRELILFLIFPFIGLAADLWLMVSLDHLAVYLGLSWLAIGVVY
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVLTGGFRRQPPEMDFQEAA
HHHHHCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]