Click here to switch to the map view.

The map label for this gene is tagO [H]

Identifier: 77460274

GI number: 77460274

Start: 4578426

End: 4579436

Strand: Reverse

Name: tagO [H]

Synonym: Pfl01_4053

Alternate gene names: 77460274

Gene position: 4579436-4578426 (Counterclockwise)

Preceding gene: 77460275

Following gene: 77460272

Centisome position: 71.13

GC content: 58.46

Gene sequence:

>1011_bases
ATGATTTTCTGGAGTATTTTGCTTGTCGTTTTTCTCCTGTCCTGGGGGTTGACGCTGGTCTTGCGGCGTTACGCGCTGGC
CAGAAGCCTGATGGATGTGCCGAATGAGCGCAGTTCCCATTCGATTCCAACGCCCAGGGGAGGCGGTGTTGCGATTGTGG
TGGCATTTGCCCTGGCTTTGCCGTTGCTGGTCGCGGCAGGGCTTTTCGAACAGGCCGCGATGATCGGTATTCTGGGCGCC
GGATTGTTGGTTGCAGTGATTGGCTTCGCCGATGATCACGGACATATCGCTGCCCGTTGGCGTCTGCTTGGGCACTTTAT
TGCTGCCGGCTGGGCGTTGTTCTGGATCAAGGGTCTGGCGCCTGTCCCATTGTTTGGCGCACTGGTTGACCTGCGATTGC
TTGGCGACCTGCTTGCCGTGATCTATCTGGTGTGGATGCTCAATCTGTATAACTTCATGGATGGCATTGACGGCCTGGCC
AGTGCTGAAGCCATCAGTGTCTGTCTGGCGGTCTGCGTTGTTTACGGCTGGTGCGGCCATCCCGACTTGATCGGTGGCGC
GCTGGTTCTGGCTGCGGCTGTCGCCGGTTTTCTTTGCTGGAATTTCCCGCCTGCACGGATCTTCATGGGGGATGCGGGCA
GCGGGTTTCTCGGCATGGTGCTGGGAGCCATGGCGCTTCAAGCGGCGTGGGAGAAACCGGAGCTGCTGTGGAGTTGGTTG
ATTCTGTTGGGGGTTTTCATTGTTGACGCTACCTGGACGCTGGTCCGGCGGTTGCTAAAGGGCGACAAGGTGTATCAGGC
TCACCGTAGTCATGCCTATCAGCATGCTGCGCAACGCACTTCGAGTCATCTGGCCGTCACATCGGCGGTGGTGGTGATCA
ACGTGGTCTGGTTGTTGCCATGGGCGTTGCTGGCTGGAACCGGTGTTGTGCCAGGTGTTCTGGGCTGTATGGTCGCCTAC
GTGCCGTTGGCATTCATCGCCTGGAAGTACAGGGCTGGCCTGGCAGCGTAA

Upstream 100 bases:

>100_bases
ATATCAGGCATACACGAGAGGTGTTGGGTTGGACACCTCCCTCTAGGGTGGAGAGGGCATTGCGCCAGACCGCTGACTAC
TACCTGGATACCAAGAACAG

Downstream 100 bases:

>100_bases
ATCGTCGTACTGACAGGCGCGGGCCCGTCAGTCGTCCGCTTAGATCTTGTTCATCAGCGTAGCGACGATCAGGCTGATGT
TGCCTTTGAGTGTCTGGCGG

Product: glycosyl transferase family protein

Products: Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine; UMP [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MIFWSILLVVFLLSWGLTLVLRRYALARSLMDVPNERSSHSIPTPRGGGVAIVVAFALALPLLVAAGLFEQAAMIGILGA
GLLVAVIGFADDHGHIAARWRLLGHFIAAGWALFWIKGLAPVPLFGALVDLRLLGDLLAVIYLVWMLNLYNFMDGIDGLA
SAEAISVCLAVCVVYGWCGHPDLIGGALVLAAAVAGFLCWNFPPARIFMGDAGSGFLGMVLGAMALQAAWEKPELLWSWL
ILLGVFIVDATWTLVRRLLKGDKVYQAHRSHAYQHAAQRTSSHLAVTSAVVVINVVWLLPWALLAGTGVVPGVLGCMVAY
VPLAFIAWKYRAGLAA

Sequences:

>Translated_336_residues
MIFWSILLVVFLLSWGLTLVLRRYALARSLMDVPNERSSHSIPTPRGGGVAIVVAFALALPLLVAAGLFEQAAMIGILGA
GLLVAVIGFADDHGHIAARWRLLGHFIAAGWALFWIKGLAPVPLFGALVDLRLLGDLLAVIYLVWMLNLYNFMDGIDGLA
SAEAISVCLAVCVVYGWCGHPDLIGGALVLAAAVAGFLCWNFPPARIFMGDAGSGFLGMVLGAMALQAAWEKPELLWSWL
ILLGVFIVDATWTLVRRLLKGDKVYQAHRSHAYQHAAQRTSSHLAVTSAVVVINVVWLLPWALLAGTGVVPGVLGCMVAY
VPLAFIAWKYRAGLAA
>Mature_336_residues
MIFWSILLVVFLLSWGLTLVLRRYALARSLMDVPNERSSHSIPTPRGGGVAIVVAFALALPLLVAAGLFEQAAMIGILGA
GLLVAVIGFADDHGHIAARWRLLGHFIAAGWALFWIKGLAPVPLFGALVDLRLLGDLLAVIYLVWMLNLYNFMDGIDGLA
SAEAISVCLAVCVVYGWCGHPDLIGGALVLAAAVAGFLCWNFPPARIFMGDAGSGFLGMVLGAMALQAAWEKPELLWSWL
ILLGVFIVDATWTLVRRLLKGDKVYQAHRSHAYQHAAQRTSSHLAVTSAVVVINVVWLLPWALLAGTGVVPGVLGCMVAY
VPLAFIAWKYRAGLAA

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.13 [C]

Molecular weight: Translated: 36015; Mature: 36015

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFWSILLVVFLLSWGLTLVLRRYALARSLMDVPNERSSHSIPTPRGGGVAIVVAFALAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
PLLVAAGLFEQAAMIGILGAGLLVAVIGFADDHGHIAARWRLLGHFIAAGWALFWIKGLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PVPLFGALVDLRLLGDLLAVIYLVWMLNLYNFMDGIDGLASAEAISVCLAVCVVYGWCGH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDLIGGALVLAAAVAGFLCWNFPPARIFMGDAGSGFLGMVLGAMALQAAWEKPELLWSWL
HHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
ILLGVFIVDATWTLVRRLLKGDKVYQAHRSHAYQHAAQRTSSHLAVTSAVVVINVVWLLP
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WALLAGTGVVPGVLGCMVAYVPLAFIAWKYRAGLAA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIFWSILLVVFLLSWGLTLVLRRYALARSLMDVPNERSSHSIPTPRGGGVAIVVAFALAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
PLLVAAGLFEQAAMIGILGAGLLVAVIGFADDHGHIAARWRLLGHFIAAGWALFWIKGLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PVPLFGALVDLRLLGDLLAVIYLVWMLNLYNFMDGIDGLASAEAISVCLAVCVVYGWCGH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDLIGGALVLAAAVAGFLCWNFPPARIFMGDAGSGFLGMVLGAMALQAAWEKPELLWSWL
HHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
ILLGVFIVDATWTLVRRLLKGDKVYQAHRSHAYQHAAQRTSSHLAVTSAVVVINVVWLLP
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WALLAGTGVVPGVLGCMVAYVPLAFIAWKYRAGLAA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Undecaprenyl phosphate; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine [C]

Specific reaction: Undecaprenyl phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine --> Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP [C]

General reaction: Substituted phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]