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The map label for this gene is galE [H]

Identifier: 77460275

GI number: 77460275

Start: 4579433

End: 4580395

Strand: Reverse

Name: galE [H]

Synonym: Pfl01_4054

Alternate gene names: 77460275

Gene position: 4580395-4579433 (Counterclockwise)

Preceding gene: 77460276

Following gene: 77460274

Centisome position: 71.14

GC content: 59.29

Gene sequence:

>963_bases
ATGAACATGCCAAGAGTGTTGGTAACCGGCGCCAGAGGATTTGTCGGTGAGGCGGTGGTCTTCAGGTTGCTGCTTGATCG
GCGAGTGGTTCCGGTGGCTGCCGCCAGGGGCGAGACGCGTCTCAAGGGTTTGTGTCCGATTGTGTCGCTGGAGCTCGGCG
ATCAAGCTGCGCTTCCTGATTTGAACGGCATTGACGTCATTGTGCATGCCGCTGCGCGGGTGCACGTCATGGACGATTCG
TCCTCTGATCCGCTGGCGGAATATCGGCGGGTGAATGTCGATGGGACCCTCCAGCTGGCGCAGCAGGCCTCAGCGGCGGG
CGTCAAACGGTTTATTTTCATCAGCAGTATCAAGGTCAATGGCGAGCAGACCGAGCCTGATCGGCCATTTACTGCGCTGG
ATCGGCCCATGCCGAAAGACCCGTATGGCGTTTCCAAGCTGGAGGCGGAGCTTGCCTTGCAAAAGCTCGCTCAGGAGACC
GGCATGGAAGTGGTCATCATCCGGCCGCCGTTGGTCTACGGGCCGGGAGTCCGGGCAAACTTTCTCAGCATGATGCGCTG
GCTCGATAAAGGCGTGCCGTTGCCGTTCGGTGCGATCGATAATCGTCGAAGTCTGGTTTCGCTGACCAATCTTGTCGATC
TCGTGGTGACCTGTATCGATCACCCGAAGGCTGCGGGGCAGGTGTTTCTTGTCAGTGATGGCGAGGATCTGTCGACGACC
ACGCTCTTGAGCGGCATGGCGCGTGCGCTCGGGAAAACAGCGGCGCTGGTGCCGCTCCCTGCGGTATTGCTGACATGGCC
TGCCAAGCTGCTTGGAAAAGGAGCGTTGGCGCAGAGGCTCTGTGGCTCCTTGCAAGTCGATATCAGGCATACACGAGAGG
TGTTGGGTTGGACACCTCCCTCTAGGGTGGAGAGGGCATTGCGCCAGACCGCTGACTACTACCTGGATACCAAGAACAGA
TGA

Upstream 100 bases:

>100_bases
AGCTGTCCCTGAGTGCCTGCAGGTGCCGGCGCCGGGGCAGGGACAAGTTGTTCTTTTTCTTCGTGTGCTGGCTGACCGCG
CTGGTTGGAAACAAGGCCGA

Downstream 100 bases:

>100_bases
TTTTCTGGAGTATTTTGCTTGTCGTTTTTCTCCTGTCCTGGGGGTTGACGCTGGTCTTGCGGCGTTACGCGCTGGCCAGA
AGCCTGATGGATGTGCCGAA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MNMPRVLVTGARGFVGEAVVFRLLLDRRVVPVAAARGETRLKGLCPIVSLELGDQAALPDLNGIDVIVHAAARVHVMDDS
SSDPLAEYRRVNVDGTLQLAQQASAAGVKRFIFISSIKVNGEQTEPDRPFTALDRPMPKDPYGVSKLEAELALQKLAQET
GMEVVIIRPPLVYGPGVRANFLSMMRWLDKGVPLPFGAIDNRRSLVSLTNLVDLVVTCIDHPKAAGQVFLVSDGEDLSTT
TLLSGMARALGKTAALVPLPAVLLTWPAKLLGKGALAQRLCGSLQVDIRHTREVLGWTPPSRVERALRQTADYYLDTKNR

Sequences:

>Translated_320_residues
MNMPRVLVTGARGFVGEAVVFRLLLDRRVVPVAAARGETRLKGLCPIVSLELGDQAALPDLNGIDVIVHAAARVHVMDDS
SSDPLAEYRRVNVDGTLQLAQQASAAGVKRFIFISSIKVNGEQTEPDRPFTALDRPMPKDPYGVSKLEAELALQKLAQET
GMEVVIIRPPLVYGPGVRANFLSMMRWLDKGVPLPFGAIDNRRSLVSLTNLVDLVVTCIDHPKAAGQVFLVSDGEDLSTT
TLLSGMARALGKTAALVPLPAVLLTWPAKLLGKGALAQRLCGSLQVDIRHTREVLGWTPPSRVERALRQTADYYLDTKNR
>Mature_320_residues
MNMPRVLVTGARGFVGEAVVFRLLLDRRVVPVAAARGETRLKGLCPIVSLELGDQAALPDLNGIDVIVHAAARVHVMDDS
SSDPLAEYRRVNVDGTLQLAQQASAAGVKRFIFISSIKVNGEQTEPDRPFTALDRPMPKDPYGVSKLEAELALQKLAQET
GMEVVIIRPPLVYGPGVRANFLSMMRWLDKGVPLPFGAIDNRRSLVSLTNLVDLVVTCIDHPKAAGQVFLVSDGEDLSTT
TLLSGMARALGKTAALVPLPAVLLTWPAKLLGKGALAQRLCGSLQVDIRHTREVLGWTPPSRVERALRQTADYYLDTKNR

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7657641, Length=335, Percent_Identity=23.2835820895522, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786974, Length=173, Percent_Identity=34.1040462427746, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34727; Mature: 34727

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMPRVLVTGARGFVGEAVVFRLLLDRRVVPVAAARGETRLKGLCPIVSLELGDQAALPD
CCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEHHCCCCHHHHCCCCEEEEECCCCCCCCC
LNGIDVIVHAAARVHVMDDSSSDPLAEYRRVNVDGTLQLAQQASAAGVKRFIFISSIKVN
CCCHHHEEEEEEEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHEEEEEEEEEEEC
GEQTEPDRPFTALDRPMPKDPYGVSKLEAELALQKLAQETGMEVVIIRPPLVYGPGVRAN
CCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCEEECCCCHHH
FLSMMRWLDKGVPLPFGAIDNRRSLVSLTNLVDLVVTCIDHPKAAGQVFLVSDGEDLSTT
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHH
TLLSGMARALGKTAALVPLPAVLLTWPAKLLGKGALAQRLCGSLQVDIRHTREVLGWTPP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEHHHHHHHHHCCCCH
SRVERALRQTADYYLDTKNR
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNMPRVLVTGARGFVGEAVVFRLLLDRRVVPVAAARGETRLKGLCPIVSLELGDQAALPD
CCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEHHCCCCHHHHCCCCEEEEECCCCCCCCC
LNGIDVIVHAAARVHVMDDSSSDPLAEYRRVNVDGTLQLAQQASAAGVKRFIFISSIKVN
CCCHHHEEEEEEEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHEEEEEEEEEEEC
GEQTEPDRPFTALDRPMPKDPYGVSKLEAELALQKLAQETGMEVVIIRPPLVYGPGVRAN
CCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCEEECCCCHHH
FLSMMRWLDKGVPLPFGAIDNRRSLVSLTNLVDLVVTCIDHPKAAGQVFLVSDGEDLSTT
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHH
TLLSGMARALGKTAALVPLPAVLLTWPAKLLGKGALAQRLCGSLQVDIRHTREVLGWTPP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEHHHHHHHHHCCCCH
SRVERALRQTADYYLDTKNR
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8820651; 10521656 [H]