Click here to switch to the map view.

The map label for this gene is ycdJ [C]

Identifier: 77460143

GI number: 77460143

Start: 4438085

End: 4438960

Strand: Direct

Name: ycdJ [C]

Synonym: Pfl01_3922

Alternate gene names: 77460143

Gene position: 4438085-4438960 (Clockwise)

Preceding gene: 77460142

Following gene: 77460144

Centisome position: 68.93

GC content: 63.7

Gene sequence:

>876_bases
ATGTTTGCCGGATTCGTCAAAGACCAGCGCCACGTCAACGGTGTGGACATCACCTACCGCATCAAAGGCAGCGGCCCGGG
CCTGCTGCTCCTGCATGGGCACCCACAGACCCACGTCATCTGGCACAAGATCGCCGGGCAACTGGCCGAACACTTCACTG
TGGTCGCTGCTGACCTGCGTGGTTACGGCGACAGCAGTCGTCCGCCGGCGGATGAAGCTCACCTCAACTATTCCAAGCGC
GAGATGGCCCGCGACGGCGTGGAATTGATGAACGCGTTGGGTTTCGAGCAGTTCTCGATCCTTGCCCACGACCGTGGCGC
GCGGGTCGCCCATCGTCTGGCGCTCGATCATCCCGCCGTCGTGCGGCGCATGGTCCTGCTCGACATCGCGCCGACGCTGG
CGATGTACAGCCAGACCAACGAAGCTTTTGCACGGGCCTATTGGCACTGGTTTTTCCTGATTCGTCCGGCACCGCTGCCG
GAAACCCTGATCGAAGCCGACCCTGAAGGCTATCTGCGCAGCGTCATGGGCAGTCGCAGCGCCGGGCTCGCGCCCTTCAC
CGACGAGGCGTTCAGCGAATACCGGCGTTGTCTCGAACGTCCCGGCAGTGCTCGGGGGATCTGTGAGGATTACCGCGCCA
GCGCCGGCATCGACCTGGAACATGACCGCATCGACATCACGGCCGGTCGTCACCTGGACCTGCCGTTACTGGTGCTGTGG
GGCGCCGAGGGCATTGTCGGTCGGTGCTTCGATCCGCTCGGGGAATGGCAACAGGTTGCCACCGACGTACGGGGCAAGGC
CCTGCCTGCCGGGCATTACCTCGCCGAAGAAGTCCCTGAACTGTTGCTCGCCGAAGCGCTCGATTTTCTCCGCTGA

Upstream 100 bases:

>100_bases
CGAACACGATTCATGAACCGTCGAACCACGCTTCACGTCTTGTCATGAACGCCCGGCGATTTCAGGATGCAGGCCACGCG
CCTGAATAAAGGATCACCCG

Downstream 100 bases:

>100_bases
CTCCCTCCTTCAATCCGGCGGCATGCGCCGTCGGACTGCTTCGCCTCCCCCGCAGAAATCCGCCCACGCGACAGCCACCT
GTAATCGCGAAACATTTACT

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MFAGFVKDQRHVNGVDITYRIKGSGPGLLLLHGHPQTHVIWHKIAGQLAEHFTVVAADLRGYGDSSRPPADEAHLNYSKR
EMARDGVELMNALGFEQFSILAHDRGARVAHRLALDHPAVVRRMVLLDIAPTLAMYSQTNEAFARAYWHWFFLIRPAPLP
ETLIEADPEGYLRSVMGSRSAGLAPFTDEAFSEYRRCLERPGSARGICEDYRASAGIDLEHDRIDITAGRHLDLPLLVLW
GAEGIVGRCFDPLGEWQQVATDVRGKALPAGHYLAEEVPELLLAEALDFLR

Sequences:

>Translated_291_residues
MFAGFVKDQRHVNGVDITYRIKGSGPGLLLLHGHPQTHVIWHKIAGQLAEHFTVVAADLRGYGDSSRPPADEAHLNYSKR
EMARDGVELMNALGFEQFSILAHDRGARVAHRLALDHPAVVRRMVLLDIAPTLAMYSQTNEAFARAYWHWFFLIRPAPLP
ETLIEADPEGYLRSVMGSRSAGLAPFTDEAFSEYRRCLERPGSARGICEDYRASAGIDLEHDRIDITAGRHLDLPLLVLW
GAEGIVGRCFDPLGEWQQVATDVRGKALPAGHYLAEEVPELLLAEALDFLR
>Mature_291_residues
MFAGFVKDQRHVNGVDITYRIKGSGPGLLLLHGHPQTHVIWHKIAGQLAEHFTVVAADLRGYGDSSRPPADEAHLNYSKR
EMARDGVELMNALGFEQFSILAHDRGARVAHRLALDHPAVVRRMVLLDIAPTLAMYSQTNEAFARAYWHWFFLIRPAPLP
ETLIEADPEGYLRSVMGSRSAGLAPFTDEAFSEYRRCLERPGSARGICEDYRASAGIDLEHDRIDITAGRHLDLPLLVLW
GAEGIVGRCFDPLGEWQQVATDVRGKALPAGHYLAEEVPELLLAEALDFLR

Specific function: Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has low activity towards chloroacetate [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=227, Percent_Identity=28.6343612334802, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI13376164, Length=227, Percent_Identity=28.6343612334802, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI218777837, Length=250, Percent_Identity=24.4, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17554012, Length=297, Percent_Identity=24.5791245791246, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562298, Length=279, Percent_Identity=23.6559139784946, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 32408; Mature: 32408

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAGFVKDQRHVNGVDITYRIKGSGPGLLLLHGHPQTHVIWHKIAGQLAEHFTVVAADLR
CCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
GYGDSSRPPADEAHLNYSKREMARDGVELMNALGFEQFSILAHDRGARVAHRLALDHPAV
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHCCCHHH
VRRMVLLDIAPTLAMYSQTNEAFARAYWHWFFLIRPAPLPETLIEADPEGYLRSVMGSRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHCCCHHHHHHHHCCCC
AGLAPFTDEAFSEYRRCLERPGSARGICEDYRASAGIDLEHDRIDITAGRHLDLPLLVLW
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCEEEEE
GAEGIVGRCFDPLGEWQQVATDVRGKALPAGHYLAEEVPELLLAEALDFLR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MFAGFVKDQRHVNGVDITYRIKGSGPGLLLLHGHPQTHVIWHKIAGQLAEHFTVVAADLR
CCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
GYGDSSRPPADEAHLNYSKREMARDGVELMNALGFEQFSILAHDRGARVAHRLALDHPAV
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHCCCHHH
VRRMVLLDIAPTLAMYSQTNEAFARAYWHWFFLIRPAPLPETLIEADPEGYLRSVMGSRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHCCCHHHHHHHHCCCC
AGLAPFTDEAFSEYRRCLERPGSARGICEDYRASAGIDLEHDRIDITAGRHLDLPLLVLW
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCEEEEE
GAEGIVGRCFDPLGEWQQVATDVRGKALPAGHYLAEEVPELLLAEALDFLR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA