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The map label for this gene is glsA [H]

Identifier: 77459595

GI number: 77459595

Start: 3848257

End: 3849165

Strand: Reverse

Name: glsA [H]

Synonym: Pfl01_3373

Alternate gene names: 77459595

Gene position: 3849165-3848257 (Counterclockwise)

Preceding gene: 77459598

Following gene: 77459594

Centisome position: 59.78

GC content: 63.81

Gene sequence:

>909_bases
ATGCAAGCGCTATTGAACGAGATCCTTGACGCGGTCCGGCCCCTGATCGGGCAGGGCAAGGTGGCTGACTACATTCCCGC
CCTCGGCACCGTGCCGGCCAATCAACTGGGCATCGCCGTGTATGGCAACGACGGCGAGATGTATTGCGCCGGCGACGCCG
AGACGCCGTTCTCGGTGCAGAGTATTTCCAAGGTGTTCAGCCTGGTGCAGGCCATCGAACATTCCGGCGAGGCGATCTGG
GAACGCCTGGGCCACGAGCCGTCCGGCCAGCCGTTCAACTCGCTGGTGCAGCTGGAATTCGAACGCGGCCGTCCGCGCAA
TCCGTTCATCAATGCCGGGGCGCTGGTGATCTGCGACATCAACCAGTCGCGCTTTGCCGCACCGGCATTGTCGATGCGCG
ACTTCGTGCGGCGGCTGTCGGGCAACCCGCAGGTGATGGTCGACGGCAAGGTCGCCGATTCCGAATACCAGCACCGCGCG
CGCAACGCGGCGATGGCTTACCTGATGCAATCCTTCGGTAACTTCCACAACGACGTTGAAGCGGTGCTGCGCAGCTACTT
CAGCCACTGCGCGTTGCGCATGAATTGCATCGATCTGGCCCGGGCATTCTGTTTCCTGGCCAACGACGGATTCTGCAAGC
ACAGCGGCGAGCAGATTCTTACTCGCCGCCAGACCCAGCAAGTCAACTCGATCATGGCCACCAGCGGCCTCTACGACGAG
GCCGGCAACTTCGCCTACCGCGTCGGTCTGCCGGGCAAGAGCGGCGTCGGTGGCGGCATCGTTGCGGTGGTGCCGGGGCA
GTTCACGGTGTGCGTGTGGTCGCCGGAGCTGAACACGGCGGGCAACTCGCTGGCGGGGATGGCGGCGCTGGAAATGCTCA
GTTCGCGGATTGGCTGGTCGGTGTTCTGA

Upstream 100 bases:

>100_bases
ACACACTGCGATACACAGACCCGGTGTGATTCGATTGCCGGGCGCAGCGTCTAGCCACGGTGTCCCCGCAATCCCATGGG
GCGAGACTTCGGAACCCGGC

Downstream 100 bases:

>100_bases
GCCCGTGTTGCTTTGAGGGAGGCCAACCTATACATTTTCCGGCCGCCCTCAATATGGTGAATCCGCTCCATGTCTCTCGC
GCTCGAACGTCTCGTCGCTG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MQALLNEILDAVRPLIGQGKVADYIPALGTVPANQLGIAVYGNDGEMYCAGDAETPFSVQSISKVFSLVQAIEHSGEAIW
ERLGHEPSGQPFNSLVQLEFERGRPRNPFINAGALVICDINQSRFAAPALSMRDFVRRLSGNPQVMVDGKVADSEYQHRA
RNAAMAYLMQSFGNFHNDVEAVLRSYFSHCALRMNCIDLARAFCFLANDGFCKHSGEQILTRRQTQQVNSIMATSGLYDE
AGNFAYRVGLPGKSGVGGGIVAVVPGQFTVCVWSPELNTAGNSLAGMAALEMLSSRIGWSVF

Sequences:

>Translated_302_residues
MQALLNEILDAVRPLIGQGKVADYIPALGTVPANQLGIAVYGNDGEMYCAGDAETPFSVQSISKVFSLVQAIEHSGEAIW
ERLGHEPSGQPFNSLVQLEFERGRPRNPFINAGALVICDINQSRFAAPALSMRDFVRRLSGNPQVMVDGKVADSEYQHRA
RNAAMAYLMQSFGNFHNDVEAVLRSYFSHCALRMNCIDLARAFCFLANDGFCKHSGEQILTRRQTQQVNSIMATSGLYDE
AGNFAYRVGLPGKSGVGGGIVAVVPGQFTVCVWSPELNTAGNSLAGMAALEMLSSRIGWSVF
>Mature_302_residues
MQALLNEILDAVRPLIGQGKVADYIPALGTVPANQLGIAVYGNDGEMYCAGDAETPFSVQSISKVFSLVQAIEHSGEAIW
ERLGHEPSGQPFNSLVQLEFERGRPRNPFINAGALVICDINQSRFAAPALSMRDFVRRLSGNPQVMVDGKVADSEYQHRA
RNAAMAYLMQSFGNFHNDVEAVLRSYFSHCALRMNCIDLARAFCFLANDGFCKHSGEQILTRRQTQQVNSIMATSGLYDE
AGNFAYRVGLPGKSGVGGGIVAVVPGQFTVCVWSPELNTAGNSLAGMAALEMLSSRIGWSVF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=288, Percent_Identity=35.0694444444444, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI20336214, Length=299, Percent_Identity=32.1070234113712, Blast_Score=141, Evalue=6e-34,
Organism=Escherichia coli, GI1787804, Length=301, Percent_Identity=60.797342192691, Blast_Score=378, Evalue=1e-106,
Organism=Escherichia coli, GI1786693, Length=286, Percent_Identity=36.7132867132867, Blast_Score=184, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17507019, Length=302, Percent_Identity=33.7748344370861, Blast_Score=163, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI17532727, Length=305, Percent_Identity=33.1147540983607, Blast_Score=158, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI193204073, Length=314, Percent_Identity=33.1210191082803, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI193204075, Length=316, Percent_Identity=31.9620253164557, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281363241, Length=293, Percent_Identity=33.7883959044369, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24653162, Length=293, Percent_Identity=33.7883959044369, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI281363239, Length=293, Percent_Identity=33.7883959044369, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24653164, Length=293, Percent_Identity=33.7883959044369, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24653166, Length=286, Percent_Identity=34.6153846153846, Blast_Score=167, Evalue=7e-42,
Organism=Drosophila melanogaster, GI116008307, Length=286, Percent_Identity=34.6153846153846, Blast_Score=167, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24653158, Length=293, Percent_Identity=33.7883959044369, Blast_Score=167, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24653156, Length=293, Percent_Identity=33.7883959044369, Blast_Score=167, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 32733; Mature: 32733

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALLNEILDAVRPLIGQGKVADYIPALGTVPANQLGIAVYGNDGEMYCAGDAETPFSVQ
CHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCHHH
SISKVFSLVQAIEHSGEAIWERLGHEPSGQPFNSLVQLEFERGRPRNPFINAGALVICDI
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHEEEEECCCCCCCCCCCCCEEEEEEC
NQSRFAAPALSMRDFVRRLSGNPQVMVDGKVADSEYQHRARNAAMAYLMQSFGNFHNDVE
CCCHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
AVLRSYFSHCALRMNCIDLARAFCFLANDGFCKHSGEQILTRRQTQQVNSIMATSGLYDE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AGNFAYRVGLPGKSGVGGGIVAVVPGQFTVCVWSPELNTAGNSLAGMAALEMLSSRIGWS
CCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
VF
CC
>Mature Secondary Structure
MQALLNEILDAVRPLIGQGKVADYIPALGTVPANQLGIAVYGNDGEMYCAGDAETPFSVQ
CHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCHHH
SISKVFSLVQAIEHSGEAIWERLGHEPSGQPFNSLVQLEFERGRPRNPFINAGALVICDI
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHEEEEECCCCCCCCCCCCCEEEEEEC
NQSRFAAPALSMRDFVRRLSGNPQVMVDGKVADSEYQHRARNAAMAYLMQSFGNFHNDVE
CCCHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
AVLRSYFSHCALRMNCIDLARAFCFLANDGFCKHSGEQILTRRQTQQVNSIMATSGLYDE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AGNFAYRVGLPGKSGVGGGIVAVVPGQFTVCVWSPELNTAGNSLAGMAALEMLSSRIGWS
CCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
VF
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA