Click here to switch to the map view.

The map label for this gene is benK [H]

Identifier: 77459189

GI number: 77459189

Start: 3401150

End: 3402490

Strand: Reverse

Name: benK [H]

Synonym: Pfl01_2964

Alternate gene names: 77459189

Gene position: 3402490-3401150 (Counterclockwise)

Preceding gene: 77459190

Following gene: 77459188

Centisome position: 52.85

GC content: 57.05

Gene sequence:

>1341_bases
ATGCGAGTAATCGACGTTAATCAGTTCATCGATAAAGCACGCTTCAGCCGATTCCATTGGGGAGTGGTAACGCTTTGCGC
GCTGCTCTTGATATTCGACGGATACGACCTGTTCATCTTCGGTGTTGTGCTGCCGGCCATTATGCGCGAGTGGCAACTCA
CGCCGATCCAGGCCGGTGCACTGGGCAGTTATGCACTGTTCGGCATGATGTTCGGAGCGCTTGCGTTTGGGTCGCTGGCT
GACAGGATCGGAAGAAAGAAAAGCATCGCTATCTGCTTCACGTTGTTTTCTTCGGCAACCCTTATCAATGGTTTTGCCAG
CAATCCGACAGAGTTTGGCATTTGTCGGTTTCTTGCAGGATTGGGCTGCGGGGGGCTGATGCCTAACGCAGTCGCATTGA
TGAGCGAATTCGCCCCGAGACGTCTTCGCAGCACTTTGGTTGCGGTCATGTTCAGTGGCTACTCGCTGGGAGGCGTGCTT
GCCGCTAGCGTGGGGATTTACATGCTTCCGCTTTTCGGGTGGCAATCCATGTTCTTCGCCGCAGCCGTGCCCCTTTTGCT
GCTGCCCATGATCTTGGGGTTTTTACCCGAGTCGATCGGTTTCCTGATTCGGGCCGGGAAGGAAGGGCAGGCGCGGCGCA
TTCTGAGCAAAGTAGATCCTGCCTCGGCTCCCAGTGATAGCGATACGTTGAGACAGGCGGACAGCGAGGGCCGCGGAGTG
ATTCTGCTGGCGTTGTTTCGTGAGCGGCGCGCGTCCCGCACCCTGTGCTTGTGGGTCGCATTTTTCTGCTGCTTGCTCAT
GGTGTATGCACTCAGCTCCTGGCTGCCCAAGCTGATGGCAAATGCCGGTTACAGCTTAGGTTCAAGCCTGACCTTTCTGT
TGGCGCTGAATTTCGGTGGTATGGCCGGAGCGATCTTTGGTGGCTGGCTGGGAGACCGCTACAACCTTGGAAAAGTCACG
GTGATGTTTTTCCTGACGGCCGCCTTGTCCATCAGCCTTCTGGGATTCAAAAGTTCGACGGCATTGTTGTATCTGCTGAT
CAGTGTGGCCGGCGCGACAACCATCGGTACGCAAATTCTCCTGTACGCCGCCACTGCCCAGTTCTACGGCATGTCGATTC
GCTCCACTGGCCTTGGATGGGCATCGGGTATCGGTCGCAATGGCGCGATCCTGGGGCCGCTGCTGGGGGGAGCACTGCTG
GGCATTGGCCTGCCGCTGCCATTGAATTTCGTTGCGTTCGCGGTTCCAGGCGCCATTGCCGCGATAGCCATGGCGCTGTT
CACCCTGGTCGGCAAAAGAAGCGTGGCCGATTCGAGTGTTTTGATGGCCGCCAAACCGTAA

Upstream 100 bases:

>100_bases
GTGGCGGTGACCTCGGCTGACCAGGAAAACTTGTCGCATCAGGCGCGACAGATTGCATCGCCGATGTAGTTCCCAAAATA
AAAACAAGAGTAACGACGCC

Downstream 100 bases:

>100_bases
CCAATCTTGCCTTGTTCCTTGAGCGGAACCAGGTGTCTCTCAGTTCACGTATCGGAATATTGTCATGAGCCAAGTCCTGA
TCCACAGCCTGTCGGCGATC

Product: hypothetical protein

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MRVIDVNQFIDKARFSRFHWGVVTLCALLLIFDGYDLFIFGVVLPAIMREWQLTPIQAGALGSYALFGMMFGALAFGSLA
DRIGRKKSIAICFTLFSSATLINGFASNPTEFGICRFLAGLGCGGLMPNAVALMSEFAPRRLRSTLVAVMFSGYSLGGVL
AASVGIYMLPLFGWQSMFFAAAVPLLLLPMILGFLPESIGFLIRAGKEGQARRILSKVDPASAPSDSDTLRQADSEGRGV
ILLALFRERRASRTLCLWVAFFCCLLMVYALSSWLPKLMANAGYSLGSSLTFLLALNFGGMAGAIFGGWLGDRYNLGKVT
VMFFLTAALSISLLGFKSSTALLYLLISVAGATTIGTQILLYAATAQFYGMSIRSTGLGWASGIGRNGAILGPLLGGALL
GIGLPLPLNFVAFAVPGAIAAIAMALFTLVGKRSVADSSVLMAAKP

Sequences:

>Translated_446_residues
MRVIDVNQFIDKARFSRFHWGVVTLCALLLIFDGYDLFIFGVVLPAIMREWQLTPIQAGALGSYALFGMMFGALAFGSLA
DRIGRKKSIAICFTLFSSATLINGFASNPTEFGICRFLAGLGCGGLMPNAVALMSEFAPRRLRSTLVAVMFSGYSLGGVL
AASVGIYMLPLFGWQSMFFAAAVPLLLLPMILGFLPESIGFLIRAGKEGQARRILSKVDPASAPSDSDTLRQADSEGRGV
ILLALFRERRASRTLCLWVAFFCCLLMVYALSSWLPKLMANAGYSLGSSLTFLLALNFGGMAGAIFGGWLGDRYNLGKVT
VMFFLTAALSISLLGFKSSTALLYLLISVAGATTIGTQILLYAATAQFYGMSIRSTGLGWASGIGRNGAILGPLLGGALL
GIGLPLPLNFVAFAVPGAIAAIAMALFTLVGKRSVADSSVLMAAKP
>Mature_446_residues
MRVIDVNQFIDKARFSRFHWGVVTLCALLLIFDGYDLFIFGVVLPAIMREWQLTPIQAGALGSYALFGMMFGALAFGSLA
DRIGRKKSIAICFTLFSSATLINGFASNPTEFGICRFLAGLGCGGLMPNAVALMSEFAPRRLRSTLVAVMFSGYSLGGVL
AASVGIYMLPLFGWQSMFFAAAVPLLLLPMILGFLPESIGFLIRAGKEGQARRILSKVDPASAPSDSDTLRQADSEGRGV
ILLALFRERRASRTLCLWVAFFCCLLMVYALSSWLPKLMANAGYSLGSSLTFLLALNFGGMAGAIFGGWLGDRYNLGKVT
VMFFLTAALSISLLGFKSSTALLYLLISVAGATTIGTQILLYAATAQFYGMSIRSTGLGWASGIGRNGAILGPLLGGALL
GIGLPLPLNFVAFAVPGAIAAIAMALFTLVGKRSVADSSVLMAAKP

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=426, Percent_Identity=25.8215962441315, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI7662270, Length=226, Percent_Identity=28.3185840707965, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI73695465, Length=318, Percent_Identity=24.8427672955975, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI213021148, Length=441, Percent_Identity=23.1292517006803, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI216548223, Length=219, Percent_Identity=29.6803652968037, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI262399383, Length=168, Percent_Identity=29.1666666666667, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI296080721, Length=381, Percent_Identity=23.3595800524934, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI296080719, Length=381, Percent_Identity=23.3595800524934, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI24497499, Length=381, Percent_Identity=23.3595800524934, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI24497497, Length=387, Percent_Identity=27.390180878553, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI296080734, Length=345, Percent_Identity=23.768115942029, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI90669191, Length=399, Percent_Identity=27.0676691729323, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87081723, Length=415, Percent_Identity=33.4939759036145, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI87082404, Length=410, Percent_Identity=25.1219512195122, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082159, Length=383, Percent_Identity=29.242819843342, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI87082231, Length=412, Percent_Identity=25, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786229, Length=280, Percent_Identity=25, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788068, Length=405, Percent_Identity=22.7160493827161, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788074, Length=346, Percent_Identity=23.6994219653179, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1789312, Length=277, Percent_Identity=28.158844765343, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=461, Percent_Identity=24.295010845987, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17560496, Length=354, Percent_Identity=25.7062146892655, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19922874, Length=433, Percent_Identity=22.4018475750577, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640198, Length=220, Percent_Identity=25.9090909090909, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640196, Length=220, Percent_Identity=25.9090909090909, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640200, Length=220, Percent_Identity=25.9090909090909, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19922616, Length=373, Percent_Identity=23.8605898123324, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47292; Mature: 47292

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00120 LIPASE_SER ; PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIDVNQFIDKARFSRFHWGVVTLCALLLIFDGYDLFIFGVVLPAIMREWQLTPIQAGA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCC
LGSYALFGMMFGALAFGSLADRIGRKKSIAICFTLFSSATLINGFASNPTEFGICRFLAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LGCGGLMPNAVALMSEFAPRRLRSTLVAVMFSGYSLGGVLAASVGIYMLPLFGWQSMFFA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAVPLLLLPMILGFLPESIGFLIRAGKEGQARRILSKVDPASAPSDSDTLRQADSEGRGV
HHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCE
ILLALFRERRASRTLCLWVAFFCCLLMVYALSSWLPKLMANAGYSLGSSLTFLLALNFGG
EEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEECCCC
MAGAIFGGWLGDRYNLGKVTVMFFLTAALSISLLGFKSSTALLYLLISVAGATTIGTQIL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
LYAATAQFYGMSIRSTGLGWASGIGRNGAILGPLLGGALLGIGLPLPLNFVAFAVPGAIA
HHHHHHHHHCCCHHCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AIAMALFTLVGKRSVADSSVLMAAKP
HHHHHHHHHHHCCCCCCCCEEEECCC
>Mature Secondary Structure
MRVIDVNQFIDKARFSRFHWGVVTLCALLLIFDGYDLFIFGVVLPAIMREWQLTPIQAGA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCC
LGSYALFGMMFGALAFGSLADRIGRKKSIAICFTLFSSATLINGFASNPTEFGICRFLAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LGCGGLMPNAVALMSEFAPRRLRSTLVAVMFSGYSLGGVLAASVGIYMLPLFGWQSMFFA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAVPLLLLPMILGFLPESIGFLIRAGKEGQARRILSKVDPASAPSDSDTLRQADSEGRGV
HHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCE
ILLALFRERRASRTLCLWVAFFCCLLMVYALSSWLPKLMANAGYSLGSSLTFLLALNFGG
EEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEECCCC
MAGAIFGGWLGDRYNLGKVTVMFFLTAALSISLLGFKSSTALLYLLISVAGATTIGTQIL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
LYAATAQFYGMSIRSTGLGWASGIGRNGAILGPLLGGALLGIGLPLPLNFVAFAVPGAIA
HHHHHHHHHCCCHHCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AIAMALFTLVGKRSVADSSVLMAAKP
HHHHHHHHHHHCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]