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The map label for this gene is ttuB [H]

Identifier: 77459128

GI number: 77459128

Start: 3347076

End: 3348374

Strand: Direct

Name: ttuB [H]

Synonym: Pfl01_2903

Alternate gene names: 77459128

Gene position: 3347076-3348374 (Clockwise)

Preceding gene: 77459127

Following gene: 77459129

Centisome position: 51.99

GC content: 62.05

Gene sequence:

>1299_bases
ATGAAAACCGCAACCCTCGCCACCCGCCGCTGGTGGTACATCATGCCGATCGTGTTCATCACCTATAGCCTGGCGTACCT
GGACCGCGCCAATTATGGATTCGCTGCTGCCTCCGGAATGGCTGAAGACCTGATGATCACGCCGGGCCTGTCCTCGCTGC
TCGGCGCGCTGTTCTTCCTCGGTTACTTTTTCTTCCAGGTGCCCGGCGCGATCTACGCGCAAAAGCACAGCGTCAAGAAG
CTGATCTTCGTCAGCCTGATCCTCTGGGGCGGGCTCGCCACACTGACCGGCGTGGTCTCCAACGCCTATTGGCTGATTGT
CATCCGCTTCATGCTCGGCGTGGTCGAAGCGGCGGTGATGCCGGCGATGCTGGTGTACCTGTGCCACTGGTTCACCCGCG
CCGAACGCTCGCGGGCCAACACCTTCCTGATCCTCGGCAACCCGGTGACGATGCTGTGGATGTCGGTGGTTTCCGGGTAT
CTGGTGCAGCATTTCAGTTGGCGCTGGATGTTCATCATCGAAGGTCTGCCGGCAGTCCTTTGGGCCTTTATCTGGTGGAA
GCTGGCCGATGATCGTCCGGCCCAGGCCAAGTGGCTCAGCGATCAGGAGAAGCACGATCTGGAAAGCGCGCTCGCCGCCG
AACAGGTCGGGATCAAAGCGGTGAAGAACTACGCAGAAGCTTTTCGTTCGCCGAAGGTGATCATTCTGGCGCTGCAATTC
TTCTGCTGGAGCATCGGCGTCTACGGCTTCGTGTTGTGGCTGCCGTCGATCCTCAAGGCCGGCGCGCAGATGGACATGAT
CGAGGCCGGCTGGCTGTCGGCGTTGCCGTATCTGGCGGCGGTGATCGGGATGCTGCTGGTGTCGTGGGGCTCGGACAAGC
TGCAAAAGCGTAAACGTTTCGTCTGGCCACCGCTGCTGATTGCCTCAGTGGCGTTCTACGGCTCCTACGCGTTGGGCGCG
GAGCATTTCTGGTGGTCGTACACGCTGCTGGTGATTGCCGGCGCCTGCATGTACGCGCCTTACGGGCCGTTCTTCGCCAT
CGTCCCGGAGATTCTGCCGGCCAACGTGGCCGGTGGCGCCATGGCGCTGATCAACAGCATGGGCGCCCTCGGTTCGTTCG
GCGGCTCGTATCTGGTCGGTTACCTGAACAGCTCCACCGGTTCGCCCGGCGCTTCGTATCTGTTGATGAGTGGCGCGCTG
ATGCTCTCGGTGGTGCTGACCATTTTTCTCAAGCCCGGCGCGAGCGACCGGGTGACGGCCAAGCGCGTCGCACCGCGTCC
GCTGCCGGCCCATTCCTGA

Upstream 100 bases:

>100_bases
ACAAAACCTGTGGGAGCTGGCTTGCCAGCGATGAGGCCCTGACAGACAACACATTTTTTGAACCTGCTGCGACAAAAACA
ACAAGCTCAGGAGCAAGACC

Downstream 100 bases:

>100_bases
ATTGATAGAGAGATGACTGCGATGAAAAAGCAGGTTGTGTTGTACAAGAAACTGTCGCCGGCGCTGATGGCGCGCCTTGA
GGAACAGGTCGATGTGACGC

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MKTATLATRRWWYIMPIVFITYSLAYLDRANYGFAAASGMAEDLMITPGLSSLLGALFFLGYFFFQVPGAIYAQKHSVKK
LIFVSLILWGGLATLTGVVSNAYWLIVIRFMLGVVEAAVMPAMLVYLCHWFTRAERSRANTFLILGNPVTMLWMSVVSGY
LVQHFSWRWMFIIEGLPAVLWAFIWWKLADDRPAQAKWLSDQEKHDLESALAAEQVGIKAVKNYAEAFRSPKVIILALQF
FCWSIGVYGFVLWLPSILKAGAQMDMIEAGWLSALPYLAAVIGMLLVSWGSDKLQKRKRFVWPPLLIASVAFYGSYALGA
EHFWWSYTLLVIAGACMYAPYGPFFAIVPEILPANVAGGAMALINSMGALGSFGGSYLVGYLNSSTGSPGASYLLMSGAL
MLSVVLTIFLKPGASDRVTAKRVAPRPLPAHS

Sequences:

>Translated_432_residues
MKTATLATRRWWYIMPIVFITYSLAYLDRANYGFAAASGMAEDLMITPGLSSLLGALFFLGYFFFQVPGAIYAQKHSVKK
LIFVSLILWGGLATLTGVVSNAYWLIVIRFMLGVVEAAVMPAMLVYLCHWFTRAERSRANTFLILGNPVTMLWMSVVSGY
LVQHFSWRWMFIIEGLPAVLWAFIWWKLADDRPAQAKWLSDQEKHDLESALAAEQVGIKAVKNYAEAFRSPKVIILALQF
FCWSIGVYGFVLWLPSILKAGAQMDMIEAGWLSALPYLAAVIGMLLVSWGSDKLQKRKRFVWPPLLIASVAFYGSYALGA
EHFWWSYTLLVIAGACMYAPYGPFFAIVPEILPANVAGGAMALINSMGALGSFGGSYLVGYLNSSTGSPGASYLLMSGAL
MLSVVLTIFLKPGASDRVTAKRVAPRPLPAHS
>Mature_432_residues
MKTATLATRRWWYIMPIVFITYSLAYLDRANYGFAAASGMAEDLMITPGLSSLLGALFFLGYFFFQVPGAIYAQKHSVKK
LIFVSLILWGGLATLTGVVSNAYWLIVIRFMLGVVEAAVMPAMLVYLCHWFTRAERSRANTFLILGNPVTMLWMSVVSGY
LVQHFSWRWMFIIEGLPAVLWAFIWWKLADDRPAQAKWLSDQEKHDLESALAAEQVGIKAVKNYAEAFRSPKVIILALQF
FCWSIGVYGFVLWLPSILKAGAQMDMIEAGWLSALPYLAAVIGMLLVSWGSDKLQKRKRFVWPPLLIASVAFYGSYALGA
EHFWWSYTLLVIAGACMYAPYGPFFAIVPEILPANVAGGAMALINSMGALGSFGGSYLVGYLNSSTGSPGASYLLMSGAL
MLSVVLTIFLKPGASDRVTAKRVAPRPLPAHS

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=245, Percent_Identity=26.1224489795918, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI9945322, Length=257, Percent_Identity=23.3463035019455, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI9966811, Length=241, Percent_Identity=23.2365145228216, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI21322234, Length=257, Percent_Identity=23.3463035019455, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082071, Length=375, Percent_Identity=29.6, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87082320, Length=409, Percent_Identity=24.6943765281174, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789152, Length=441, Percent_Identity=23.3560090702948, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI2367379, Length=296, Percent_Identity=21.6216216216216, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789515, Length=438, Percent_Identity=22.6027397260274, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115533556, Length=258, Percent_Identity=27.1317829457364, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115533554, Length=258, Percent_Identity=27.1317829457364, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17554962, Length=309, Percent_Identity=24.2718446601942, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17552542, Length=283, Percent_Identity=24.3816254416961, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17554148, Length=402, Percent_Identity=24.8756218905473, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86561091, Length=252, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=252, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25141318, Length=252, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71991448, Length=291, Percent_Identity=26.4604810996564, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=291, Percent_Identity=26.4604810996564, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540458, Length=245, Percent_Identity=24.0816326530612, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17566884, Length=226, Percent_Identity=25.6637168141593, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=240, Percent_Identity=23.3333333333333, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321698, Length=335, Percent_Identity=22.089552238806, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323032, Length=222, Percent_Identity=24.7747747747748, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319250, Length=302, Percent_Identity=24.8344370860927, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550460, Length=301, Percent_Identity=25.9136212624585, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24655255, Length=258, Percent_Identity=26.7441860465116, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24580790, Length=354, Percent_Identity=24.0112994350282, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28573299, Length=402, Percent_Identity=23.8805970149254, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24584153, Length=344, Percent_Identity=23.2558139534884, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20130135, Length=416, Percent_Identity=23.5576923076923, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24655271, Length=401, Percent_Identity=23.6907730673317, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24583789, Length=367, Percent_Identity=24.7956403269755, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573708, Length=251, Percent_Identity=25.8964143426295, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573707, Length=251, Percent_Identity=25.8964143426295, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653727, Length=383, Percent_Identity=23.2375979112272, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922400, Length=272, Percent_Identity=24.6323529411765, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654215, Length=272, Percent_Identity=24.6323529411765, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658674, Length=284, Percent_Identity=23.5915492957746, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24658666, Length=288, Percent_Identity=22.9166666666667, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI20130167, Length=257, Percent_Identity=25.2918287937743, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI62484226, Length=303, Percent_Identity=24.4224422442244, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47694; Mature: 47694

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTATLATRRWWYIMPIVFITYSLAYLDRANYGFAAASGMAEDLMITPGLSSLLGALFFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHEEECCCHHHHHHHHHHH
GYFFFQVPGAIYAQKHSVKKLIFVSLILWGGLATLTGVVSNAYWLIVIRFMLGVVEAAVM
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAMLVYLCHWFTRAERSRANTFLILGNPVTMLWMSVVSGYLVQHFSWRWMFIIEGLPAVL
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHH
WAFIWWKLADDRPAQAKWLSDQEKHDLESALAAEQVGIKAVKNYAEAFRSPKVIILALQF
HHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FCWSIGVYGFVLWLPSILKAGAQMDMIEAGWLSALPYLAAVIGMLLVSWGSDKLQKRKRF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
VWPPLLIASVAFYGSYALGAEHFWWSYTLLVIAGACMYAPYGPFFAIVPEILPANVAGGA
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
MALINSMGALGSFGGSYLVGYLNSSTGSPGASYLLMSGALMLSVVLTIFLKPGASDRVTA
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
KRVAPRPLPAHS
HHCCCCCCCCCC
>Mature Secondary Structure
MKTATLATRRWWYIMPIVFITYSLAYLDRANYGFAAASGMAEDLMITPGLSSLLGALFFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHEEECCCHHHHHHHHHHH
GYFFFQVPGAIYAQKHSVKKLIFVSLILWGGLATLTGVVSNAYWLIVIRFMLGVVEAAVM
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAMLVYLCHWFTRAERSRANTFLILGNPVTMLWMSVVSGYLVQHFSWRWMFIIEGLPAVL
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHH
WAFIWWKLADDRPAQAKWLSDQEKHDLESALAAEQVGIKAVKNYAEAFRSPKVIILALQF
HHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FCWSIGVYGFVLWLPSILKAGAQMDMIEAGWLSALPYLAAVIGMLLVSWGSDKLQKRKRF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
VWPPLLIASVAFYGSYALGAEHFWWSYTLLVIAGACMYAPYGPFFAIVPEILPANVAGGA
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
MALINSMGALGSFGGSYLVGYLNSSTGSPGASYLLMSGALMLSVVLTIFLKPGASDRVTA
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
KRVAPRPLPAHS
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]