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The map label for this gene is kdgK [H]

Identifier: 77459127

GI number: 77459127

Start: 3345980

End: 3347017

Strand: Direct

Name: kdgK [H]

Synonym: Pfl01_2902

Alternate gene names: 77459127

Gene position: 3345980-3347017 (Clockwise)

Preceding gene: 77459126

Following gene: 77459128

Centisome position: 51.97

GC content: 63.78

Gene sequence:

>1038_bases
ATGTCTGAGATCGATATTCTGTCGTTCGGCGAAACCATGGCCATGTTTGTCGCCGAACAGAGCGGCGATCTGGCCTTCAT
CGACCAGTTCCACAAACGGATTGCCGGGGCCGACAGCAACGTGGCCATCGGACTTTCCCGACTTGGTTTCAAGGTCGCGT
GGTTGAGCCGTGTCGGTGCCGATTCGCTGGGACGATTTGTCGTTGAGACCCTGGCCCGCGAAGGGCTGGATTGCAGTCAC
GTTGAAGTCGACCCGGCGCACCCGACCGGTTTCCAGCTCAAGTCGCGCAACGATGACGGCAACGATCCGACGGTCGAGTA
CTTCCGCCGTGGCTCGGCGGCCAGTCATCTGTCGCCGCAGTCGATCACCCCGAAACTGCTAGGCGCCCGGCATCTGCACG
CCACTGGTATTCCGCCGGCGCTGTCCGCGTCGGCCCGGGAAATGTCCCGTGAACTGATGACCCGCATGCGCAACGCCGGG
CGCAGCGTGTCGTTCGACCCGAACCTGCGCCCGAGCCTGTGGGCCGGCGAGCGGGAGATGATCCGCGAGATCAACCGCCT
CGCCGCCCTCGCCCACTGGGTGTTGCCCGGGTTGAGCGAAGGCCGGCTGCTGACCGGGTTTGAAGATCCGGCGGATATCG
CCGCGTTCTATCTCGATCAGGGTGCCGAAGCCGTGGCGATCAAACTCGGGCCGCAGGGCGCCTACTACCGCACGCATCTG
GATCAGGGGTTTGTCGCCGGGGTGCCGGTCGAGACTGTGGTCGATACGGTCGGCGCCGGCGATGGATTTGCGGTCGGGAT
GATCAGTGCCCTGCTGGAGCATCAGAGCTTTCCCGAGGCGGTCAGACGTGCCAACTGGATTGGCAGTCGGGCGGTGCAGA
GCCGGGGTGACATGGAGGGTTTGCCGACCCGTTCCGAACTAGCCGTTGAATTCGAGGCCGCCATTGCTGGCAAGTCGAAT
CGTCTCTCCGCAGCTCCCACAGTGTCCGTGGAGTACACAAAACCTGTGGGAGCTGGCTTGCCAGCGATGAGGCCCTGA

Upstream 100 bases:

>100_bases
GCCGCCGAATACCCGTTGCAGGGCGATGATCTGGTGCAGCTGACCACCGAACACGTCGCCGCCCTCGCCCGCCTCGGCCA
ATCCCGTCTGGAGCCTGCTC

Downstream 100 bases:

>100_bases
CAGACAACACATTTTTTGAACCTGCTGCGACAAAAACAACAAGCTCAGGAGCAAGACCATGAAAACCGCAACCCTCGCCA
CCCGCCGCTGGTGGTACATC

Product: PfkB

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSEIDILSFGETMAMFVAEQSGDLAFIDQFHKRIAGADSNVAIGLSRLGFKVAWLSRVGADSLGRFVVETLAREGLDCSH
VEVDPAHPTGFQLKSRNDDGNDPTVEYFRRGSAASHLSPQSITPKLLGARHLHATGIPPALSASAREMSRELMTRMRNAG
RSVSFDPNLRPSLWAGEREMIREINRLAALAHWVLPGLSEGRLLTGFEDPADIAAFYLDQGAEAVAIKLGPQGAYYRTHL
DQGFVAGVPVETVVDTVGAGDGFAVGMISALLEHQSFPEAVRRANWIGSRAVQSRGDMEGLPTRSELAVEFEAAIAGKSN
RLSAAPTVSVEYTKPVGAGLPAMRP

Sequences:

>Translated_345_residues
MSEIDILSFGETMAMFVAEQSGDLAFIDQFHKRIAGADSNVAIGLSRLGFKVAWLSRVGADSLGRFVVETLAREGLDCSH
VEVDPAHPTGFQLKSRNDDGNDPTVEYFRRGSAASHLSPQSITPKLLGARHLHATGIPPALSASAREMSRELMTRMRNAG
RSVSFDPNLRPSLWAGEREMIREINRLAALAHWVLPGLSEGRLLTGFEDPADIAAFYLDQGAEAVAIKLGPQGAYYRTHL
DQGFVAGVPVETVVDTVGAGDGFAVGMISALLEHQSFPEAVRRANWIGSRAVQSRGDMEGLPTRSELAVEFEAAIAGKSN
RLSAAPTVSVEYTKPVGAGLPAMRP
>Mature_344_residues
SEIDILSFGETMAMFVAEQSGDLAFIDQFHKRIAGADSNVAIGLSRLGFKVAWLSRVGADSLGRFVVETLAREGLDCSHV
EVDPAHPTGFQLKSRNDDGNDPTVEYFRRGSAASHLSPQSITPKLLGARHLHATGIPPALSASAREMSRELMTRMRNAGR
SVSFDPNLRPSLWAGEREMIREINRLAALAHWVLPGLSEGRLLTGFEDPADIAAFYLDQGAEAVAIKLGPQGAYYRTHLD
QGFVAGVPVETVVDTVGAGDGFAVGMISALLEHQSFPEAVRRANWIGSRAVQSRGDMEGLPTRSELAVEFEAAIAGKSNR
LSAAPTVSVEYTKPVGAGLPAMRP

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=326, Percent_Identity=28.2208588957055, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082281, Length=306, Percent_Identity=26.4705882352941, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790193, Length=293, Percent_Identity=28.6689419795222, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 37050; Mature: 36919

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIDILSFGETMAMFVAEQSGDLAFIDQFHKRIAGADSNVAIGLSRLGFKVAWLSRVGA
CCCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCH
DSLGRFVVETLAREGLDCSHVEVDPAHPTGFQLKSRNDDGNDPTVEYFRRGSAASHLSPQ
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEECCCCCCCCHHHHHHHCCCCCCCCCCC
SITPKLLGARHLHATGIPPALSASAREMSRELMTRMRNAGRSVSFDPNLRPSLWAGEREM
CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
IREINRLAALAHWVLPGLSEGRLLTGFEDPADIAAFYLDQGAEAVAIKLGPQGAYYRTHL
HHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEC
DQGFVAGVPVETVVDTVGAGDGFAVGMISALLEHQSFPEAVRRANWIGSRAVQSRGDMEG
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC
LPTRSELAVEFEAAIAGKSNRLSAAPTVSVEYTKPVGAGLPAMRP
CCCHHHHHEEEHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SEIDILSFGETMAMFVAEQSGDLAFIDQFHKRIAGADSNVAIGLSRLGFKVAWLSRVGA
CCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCH
DSLGRFVVETLAREGLDCSHVEVDPAHPTGFQLKSRNDDGNDPTVEYFRRGSAASHLSPQ
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEECCCCCCCCHHHHHHHCCCCCCCCCCC
SITPKLLGARHLHATGIPPALSASAREMSRELMTRMRNAGRSVSFDPNLRPSLWAGEREM
CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
IREINRLAALAHWVLPGLSEGRLLTGFEDPADIAAFYLDQGAEAVAIKLGPQGAYYRTHL
HHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEC
DQGFVAGVPVETVVDTVGAGDGFAVGMISALLEHQSFPEAVRRANWIGSRAVQSRGDMEG
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC
LPTRSELAVEFEAAIAGKSNRLSAAPTVSVEYTKPVGAGLPAMRP
CCCHHHHHEEEHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]