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The map label for this gene is mas [H]

Identifier: 77458179

GI number: 77458179

Start: 2226269

End: 2227267

Strand: Reverse

Name: mas [H]

Synonym: Pfl01_1952

Alternate gene names: 77458179

Gene position: 2227267-2226269 (Counterclockwise)

Preceding gene: 77458180

Following gene: 77458178

Centisome position: 34.59

GC content: 64.56

Gene sequence:

>999_bases
ATGACGTTGCCCAATGAAATGACCCGAATCGAAATCACCGAACCGGGTGGGCCCGAGGTTCTGCAATCCCGACGCGTGCC
GCTGCCGGTCGCCGCCGAAGGCGAAGTTCTGATCCGCGTGCACGCCGCCGGCGTCAATCGCCCGGACGCCCTGCAACGCG
CCGGCAAGTACCCGATGAAGCCCGGCATGAACCCGATTCCGGGCCTTGAAGTGGCCGGCGAGGTCGTGGCGATTGGCAGC
GGTGTCAGCACATTCGCGGTCGGTGACCGGGTCTGCGCGCTGACCAATGGCGGAGGTTACGCCGAATACTGCACGGTCCC
GGCCGGCCAGACTCTGCCAATTCCCGACGGGCTCGACTGGATTCAGGCTGCGGCTATTCCTGAAACCTTTTTCACTGTGT
GGGCCAACCTGTTCGGCCTCGGCGGCGCCAGCCGTGGTCAGCGCGCCTTGATCCACGGCGGCACCAGCGGCATCGGCACC
ACCGCGCTCATGCTGTGCCGCGAGTTTGGCATCGAAGCTTTCGCCACCGCCGGCAGCGCCGATAAATGTGCAGCGATCCG
CAATCTGGGCGGCGACGCGATCAACTACCGGGAACAGGAGTTCGCGGCGGTCATCGCCGAGAAAACCGCCAGCCAGGGCG
TGAATGTGATCCTCGACATCATGGGCGGCTCATACCTCAACGGGAACATCAGCGCCTTGGGAATGGATGGACGGTTGGTG
ATGCTCGGTTTCCTCGGCGGCGCGCGAGCCAATGACATCGATCTGCTGGCGATCCTCGGCAAACGTGCGGTGGTCACCGG
TTCCCTCCTCCGCGCCCGTACCTCGGCGGAAAAAGCCGCCATCGCCGATCAATTGCGCGAACACGTCTGGCCGGTGCTGG
CCGCCGGACGCTGCCTGCCGATCATCGACAAGGTCTATCCGCTCGCCGAAGCAGCCAAGGCCCATGCGCACATGGAAGCG
GGCGACCACATCGGCAAGATCGTGCTGAAGATCGACTGA

Upstream 100 bases:

>100_bases
GCCCTCCTCCGTCGAACAACGCTGCTGCGCCGAATGACGGGAATCATTGCGCCCTGACTGCGTTCCCATCTACTGATCAC
TTTTTCAAGAGGAATCGAAA

Downstream 100 bases:

>100_bases
GTCGTTGCAGCATTTTGTAATCGTTGCGGGTGGGCGGCGGTCGAAAATGTCACGCGCGTGTCCAGGCTTCTGGTAAAAAG
CGTTCTTTGTCCACGCGGTG

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTLPNEMTRIEITEPGGPEVLQSRRVPLPVAAEGEVLIRVHAAGVNRPDALQRAGKYPMKPGMNPIPGLEVAGEVVAIGS
GVSTFAVGDRVCALTNGGGYAEYCTVPAGQTLPIPDGLDWIQAAAIPETFFTVWANLFGLGGASRGQRALIHGGTSGIGT
TALMLCREFGIEAFATAGSADKCAAIRNLGGDAINYREQEFAAVIAEKTASQGVNVILDIMGGSYLNGNISALGMDGRLV
MLGFLGGARANDIDLLAILGKRAVVTGSLLRARTSAEKAAIADQLREHVWPVLAAGRCLPIIDKVYPLAEAAKAHAHMEA
GDHIGKIVLKID

Sequences:

>Translated_332_residues
MTLPNEMTRIEITEPGGPEVLQSRRVPLPVAAEGEVLIRVHAAGVNRPDALQRAGKYPMKPGMNPIPGLEVAGEVVAIGS
GVSTFAVGDRVCALTNGGGYAEYCTVPAGQTLPIPDGLDWIQAAAIPETFFTVWANLFGLGGASRGQRALIHGGTSGIGT
TALMLCREFGIEAFATAGSADKCAAIRNLGGDAINYREQEFAAVIAEKTASQGVNVILDIMGGSYLNGNISALGMDGRLV
MLGFLGGARANDIDLLAILGKRAVVTGSLLRARTSAEKAAIADQLREHVWPVLAAGRCLPIIDKVYPLAEAAKAHAHMEA
GDHIGKIVLKID
>Mature_331_residues
TLPNEMTRIEITEPGGPEVLQSRRVPLPVAAEGEVLIRVHAAGVNRPDALQRAGKYPMKPGMNPIPGLEVAGEVVAIGSG
VSTFAVGDRVCALTNGGGYAEYCTVPAGQTLPIPDGLDWIQAAAIPETFFTVWANLFGLGGASRGQRALIHGGTSGIGTT
ALMLCREFGIEAFATAGSADKCAAIRNLGGDAINYREQEFAAVIAEKTASQGVNVILDIMGGSYLNGNISALGMDGRLVM
LGFLGGARANDIDLLAILGKRAVVTGSLLRARTSAEKAAIADQLREHVWPVLAAGRCLPIIDKVYPLAEAAKAHAHMEAG
DHIGKIVLKID

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=40.9090909090909, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=40.9090909090909, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=31.4984709480122, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=31.4984709480122, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI18379349, Length=323, Percent_Identity=29.7213622291022, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI194239676, Length=327, Percent_Identity=29.9694189602446, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI24308257, Length=347, Percent_Identity=26.2247838616715, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI28557745, Length=354, Percent_Identity=29.0960451977401, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI41872631, Length=307, Percent_Identity=26.0586319218241, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI47519420, Length=367, Percent_Identity=24.7956403269755, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI197927207, Length=186, Percent_Identity=26.3440860215054, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790485, Length=318, Percent_Identity=29.2452830188679, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17507255, Length=319, Percent_Identity=28.5266457680251, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17536829, Length=215, Percent_Identity=27.4418604651163, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI212642053, Length=307, Percent_Identity=25.4071661237785, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71987554, Length=370, Percent_Identity=22.1621621621622, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=343, Percent_Identity=26.2390670553936, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=309, Percent_Identity=23.6245954692557, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=314, Percent_Identity=23.5668789808917, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19920632, Length=307, Percent_Identity=25.4071661237785, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI221330659, Length=307, Percent_Identity=25.4071661237785, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24581345, Length=303, Percent_Identity=25.7425742574257, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45550423, Length=182, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581341, Length=361, Percent_Identity=27.9778393351801, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 34597; Mature: 34466

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPNEMTRIEITEPGGPEVLQSRRVPLPVAAEGEVLIRVHAAGVNRPDALQRAGKYPMK
CCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCC
PGMNPIPGLEVAGEVVAIGSGVSTFAVGDRVCALTNGGGYAEYCTVPAGQTLPIPDGLDW
CCCCCCCCCHHCCCEEEECCCCCEEEECCEEEEEECCCCCEEEEECCCCCCCCCCCCHHH
IQAAAIPETFFTVWANLFGLGGASRGQRALIHGGTSGIGTTALMLCREFGIEAFATAGSA
HHHHHCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHEECCCCC
DKCAAIRNLGGDAINYREQEFAAVIAEKTASQGVNVILDIMGGSYLNGNISALGMDGRLV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCEEEEECCCCEE
MLGFLGGARANDIDLLAILGKRAVVTGSLLRARTSAEKAAIADQLREHVWPVLAAGRCLP
EEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IIDKVYPLAEAAKAHAHMEAGDHIGKIVLKID
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
>Mature Secondary Structure 
TLPNEMTRIEITEPGGPEVLQSRRVPLPVAAEGEVLIRVHAAGVNRPDALQRAGKYPMK
CCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCC
PGMNPIPGLEVAGEVVAIGSGVSTFAVGDRVCALTNGGGYAEYCTVPAGQTLPIPDGLDW
CCCCCCCCCHHCCCEEEECCCCCEEEECCEEEEEECCCCCEEEEECCCCCCCCCCCCHHH
IQAAAIPETFFTVWANLFGLGGASRGQRALIHGGTSGIGTTALMLCREFGIEAFATAGSA
HHHHHCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHEECCCCC
DKCAAIRNLGGDAINYREQEFAAVIAEKTASQGVNVILDIMGGSYLNGNISALGMDGRLV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCEEEEECCCCEE
MLGFLGGARANDIDLLAILGKRAVVTGSLLRARTSAEKAAIADQLREHVWPVLAAGRCLP
EEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IIDKVYPLAEAAKAHAHMEAGDHIGKIVLKID
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]