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The map label for this gene is yfhR [C]

Identifier: 77458178

GI number: 77458178

Start: 2225212

End: 2226156

Strand: Reverse

Name: yfhR [C]

Synonym: Pfl01_1951

Alternate gene names: 77458178

Gene position: 2226156-2225212 (Counterclockwise)

Preceding gene: 77458179

Following gene: 77458177

Centisome position: 34.58

GC content: 61.9

Gene sequence:

>945_bases
ATGTTCCTGGCCTTCATGACCCGAGTTCGACGCCGCCGTCTGGCGTTCGCCTGCATGGCCGCCCTGATCGTCGGCGTGCC
GGCGAGTTGTGCCGTGCTGGAACACACAGAGCGCAAGCTTCTGTTTCGCATCGAACCGGGCACCGCCGGCTGGTATCACG
GTTTGCCCGGCAGCGTGCAGGAACTCGACCTGCAACCGAAAAGCTTCAAGGCCGGGCAAAACATTCACGCCTGGTGGTGG
CCGGCAGAGCGCGCCGATGCACCGGCCATTCTTTATTTGCATGGCGTACGCTGGAATCTGACAGGGCAACTGTTTCGTAT
CGAACAATTGCGCGCGGCAGGTTATTCGGTATTGGCCATCGACTATCGCGGTTTCGGCCAGAGCCGTGGCGATCTGCCGT
CGGAAAGCACGGTGTACGAAGATGCCCGGGTAGCCTGGGAACGCTTCCAGCTGTTGCAACCCGATCCGAACAAACGCCTG
ATCTACGGGCATTCATTGGGTGGCGCGGTCGCCATCGATCTGGCTGCCGAACTCGGTCGCGACGCCACCAGAAACCACAC
CCCATTGCCGGTGCGCGGACTGGTTATCGAATCCACCTTCACCTCCTTGGCGGATGTTGCGGCAGCCGTGGCCAACACCT
CCCTTCCAGTCCGCTGGTTGCTGTCGCAGAAATTCGATTCCATCGACAAGATCGCCGAGATCCACATGCCGTTGCTGGTG
GTACACGGCCTGGCCGACGCATTCGTGCCGTCACGCTTCAGCGAACAACTGTTCGCCGCCGCCCGGCAGCCGAAACGCCT
GTTGCTGGTGCCCGGCGCAACGCACAACAACAGCATGGCGCTGGGCGGACAGAACTATCGCAAGGCAATCGATGCGCTGA
TGCAAACCCGACCTGCCGCCCGGGTGGCCGGCGCTGCGGTGCAAAAGAATCCGCGCGATTCCTGA

Upstream 100 bases:

>100_bases
TTTTGTAATCGTTGCGGGTGGGCGGCGGTCGAAAATGTCACGCGCGTGTCCAGGCTTCTGGTAAAAAGCGTTCTTTGTCC
ACGCGGTGGTGAAACGTTTA

Downstream 100 bases:

>100_bases
CGTCCCTCCCCCGCAGACCATCGGTCACCCCGAAAGGAAATTCTTGCAGCATCGGCTGGAAATTCGGCGATCTGACGCTT
TGCTGGATGGAGTCAATCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MFLAFMTRVRRRRLAFACMAALIVGVPASCAVLEHTERKLLFRIEPGTAGWYHGLPGSVQELDLQPKSFKAGQNIHAWWW
PAERADAPAILYLHGVRWNLTGQLFRIEQLRAAGYSVLAIDYRGFGQSRGDLPSESTVYEDARVAWERFQLLQPDPNKRL
IYGHSLGGAVAIDLAAELGRDATRNHTPLPVRGLVIESTFTSLADVAAAVANTSLPVRWLLSQKFDSIDKIAEIHMPLLV
VHGLADAFVPSRFSEQLFAAARQPKRLLLVPGATHNNSMALGGQNYRKAIDALMQTRPAARVAGAAVQKNPRDS

Sequences:

>Translated_314_residues
MFLAFMTRVRRRRLAFACMAALIVGVPASCAVLEHTERKLLFRIEPGTAGWYHGLPGSVQELDLQPKSFKAGQNIHAWWW
PAERADAPAILYLHGVRWNLTGQLFRIEQLRAAGYSVLAIDYRGFGQSRGDLPSESTVYEDARVAWERFQLLQPDPNKRL
IYGHSLGGAVAIDLAAELGRDATRNHTPLPVRGLVIESTFTSLADVAAAVANTSLPVRWLLSQKFDSIDKIAEIHMPLLV
VHGLADAFVPSRFSEQLFAAARQPKRLLLVPGATHNNSMALGGQNYRKAIDALMQTRPAARVAGAAVQKNPRDS
>Mature_314_residues
MFLAFMTRVRRRRLAFACMAALIVGVPASCAVLEHTERKLLFRIEPGTAGWYHGLPGSVQELDLQPKSFKAGQNIHAWWW
PAERADAPAILYLHGVRWNLTGQLFRIEQLRAAGYSVLAIDYRGFGQSRGDLPSESTVYEDARVAWERFQLLQPDPNKRL
IYGHSLGGAVAIDLAAELGRDATRNHTPLPVRGLVIESTFTSLADVAAAVANTSLPVRWLLSQKFDSIDKIAEIHMPLLV
VHGLADAFVPSRFSEQLFAAARQPKRLLLVPGATHNNSMALGGQNYRKAIDALMQTRPAARVAGAAVQKNPRDS

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=217, Percent_Identity=31.3364055299539, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI32451492, Length=221, Percent_Identity=28.0542986425339, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI32528310, Length=221, Percent_Identity=28.0542986425339, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI24308097, Length=245, Percent_Identity=30.2040816326531, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI109689718, Length=245, Percent_Identity=30.2040816326531, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI71051602, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI71051600, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI151301175, Length=194, Percent_Identity=29.8969072164948, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI226510965, Length=229, Percent_Identity=28.82096069869, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17532877, Length=157, Percent_Identity=31.2101910828025, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71985392, Length=202, Percent_Identity=27.7227722772277, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71997133, Length=211, Percent_Identity=28.436018957346, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17137566, Length=229, Percent_Identity=30.1310043668122, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281362521, Length=197, Percent_Identity=29.9492385786802, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281362519, Length=197, Percent_Identity=29.9492385786802, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28571878, Length=197, Percent_Identity=29.9492385786802, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24655464, Length=188, Percent_Identity=30.8510638297872, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24655467, Length=188, Percent_Identity=30.8510638297872, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 34650; Mature: 34650

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLAFMTRVRRRRLAFACMAALIVGVPASCAVLEHTERKLLFRIEPGTAGWYHGLPGSVQ
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHH
ELDLQPKSFKAGQNIHAWWWPAERADAPAILYLHGVRWNLTGQLFRIEQLRAAGYSVLAI
HHCCCCCHHCCCCCCEEEECCCCCCCCCEEEEEECEEECCCCHHHHHHHHHHCCCEEEEE
DYRGFGQSRGDLPSESTVYEDARVAWERFQLLQPDPNKRLIYGHSLGGAVAIDLAAELGR
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCC
DATRNHTPLPVRGLVIESTFTSLADVAAAVANTSLPVRWLLSQKFDSIDKIAEIHMPLLV
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VHGLADAFVPSRFSEQLFAAARQPKRLLLVPGATHNNSMALGGQNYRKAIDALMQTRPAA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCHHHHHHHHHHHHCCCHH
RVAGAAVQKNPRDS
HHHHHHHCCCCCCC
>Mature Secondary Structure
MFLAFMTRVRRRRLAFACMAALIVGVPASCAVLEHTERKLLFRIEPGTAGWYHGLPGSVQ
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHH
ELDLQPKSFKAGQNIHAWWWPAERADAPAILYLHGVRWNLTGQLFRIEQLRAAGYSVLAI
HHCCCCCHHCCCCCCEEEECCCCCCCCCEEEEEECEEECCCCHHHHHHHHHHCCCEEEEE
DYRGFGQSRGDLPSESTVYEDARVAWERFQLLQPDPNKRLIYGHSLGGAVAIDLAAELGR
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCC
DATRNHTPLPVRGLVIESTFTSLADVAAAVANTSLPVRWLLSQKFDSIDKIAEIHMPLLV
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VHGLADAFVPSRFSEQLFAAARQPKRLLLVPGATHNNSMALGGQNYRKAIDALMQTRPAA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCHHHHHHHHHHHHCCCHH
RVAGAAVQKNPRDS
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]