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The map label for this gene is cobT

Identifier: 77457875

GI number: 77457875

Start: 1838858

End: 1839913

Strand: Direct

Name: cobT

Synonym: Pfl01_1648

Alternate gene names: 77457875

Gene position: 1838858-1839913 (Clockwise)

Preceding gene: 77457874

Following gene: 77457876

Centisome position: 28.56

GC content: 65.44

Gene sequence:

>1056_bases
ATGACCCAAGCCTGGTGGCTGAACCCGTGCAAATCGGTGGATACGGACGCCGTTGAAAACGCGGCGGCGCGTCAGCAGCA
ATTGACCAAACCCGCCGGCTCTCTTGGGCGGCTCGAATCAGTGGCGGTGCAACTGGCCGGATTGCAGGGCCAGGTCAAAC
CGACACTCGATCACGTCTGGATTTCGATTTTTGCCGGTGACCACGGTGTTGTCGCCGAAGGGGTTTCCGCATTTCCGCAG
GAGGTCACCGGGCAGATGCTGCTGAATTTCGTCAGCGGCGGCGCGGCGATCAGTGTGCTGGCGCGACAACTTGGCGCGCA
GCTGGAAGTGGTGGATCTGGGCACCGTGACACCGTCGCTGAGCCTGCCGGGCGTGCGTCACCTGAACATCGGTCCGGGCA
CGGCGAATTTCGCCAAGGGCGCGGCGATGACTCGGGCCCAGGGTGAACTCGCCTTGCAGGGCGGTCGCGACAGTGTGCTG
CGGGCGAAAGCGGCAGGCGCGCAATTGTTCATCGGCGGTGAAATGGGCATCGGCAACACCACGGCTGCCAGTGCGCTGGC
CTGTGCGCTGCTCGATTGCCCAGTGGTTCATCTGACCGGTCCAGGCACCGGGTTGAATGCCGAAGGCGTCAGTCACAAGG
CGCAGGTGATCGAGCGCGCGCTGGCGCTACACGCAGCACAACGCGGCGATGCGTTGCAGACCCTGTTCAATCTCGGCGGC
TTCGAAATTGCGGCTTTGGTCGGCGCGTATCTGGCCTGTGCGCAGGAAGGTGTGGCGGTTTTGGTGGACGGTTTTATCTG
CACGGTCGCCGCGCTGGTGGCGGTGCGTCTGAATCCGGCTTGCCGTGAGTGGCTGCTGTTCGGTCACCGCGGTGCCGAGC
CGGGCCATCGCCATGTGCTGGAAACCCTTGGCGCGGAGCCGCTGCTTGAACTGGGTCTGCGTCTGGGCGAGGGCAGTGGC
GCGGCGCTGGCGGTGCCGTTGCTGCGTCTGGCCTGTGACCTGCACGGGCAGATGGCGACCTTCGCCGAAGCCGCGGTGGC
GGACCGCCCGGCATGA

Upstream 100 bases:

>100_bases
TCGATGAAGCCGGTTGGCTGCATCAAGCTCTGGCCGAGGGTTGTCAGCGAGTCGTCCTGACGGTCGCCGGCCTGCCTCTG
ACTCTGAAAGGACCTGCGTT

Downstream 100 bases:

>100_bases
CCTTGCGTCTGGACCTGCTGCGCCACGGTGAAACCGAACTCGGCGGCGGCCTGCGCGGCAGTCTCGACGATGCACTGACC
GAAAAGGGCTGGGCGCAGAT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTQAWWLNPCKSVDTDAVENAAARQQQLTKPAGSLGRLESVAVQLAGLQGQVKPTLDHVWISIFAGDHGVVAEGVSAFPQ
EVTGQMLLNFVSGGAAISVLARQLGAQLEVVDLGTVTPSLSLPGVRHLNIGPGTANFAKGAAMTRAQGELALQGGRDSVL
RAKAAGAQLFIGGEMGIGNTTAASALACALLDCPVVHLTGPGTGLNAEGVSHKAQVIERALALHAAQRGDALQTLFNLGG
FEIAALVGAYLACAQEGVAVLVDGFICTVAALVAVRLNPACREWLLFGHRGAEPGHRHVLETLGAEPLLELGLRLGEGSG
AALAVPLLRLACDLHGQMATFAEAAVADRPA

Sequences:

>Translated_351_residues
MTQAWWLNPCKSVDTDAVENAAARQQQLTKPAGSLGRLESVAVQLAGLQGQVKPTLDHVWISIFAGDHGVVAEGVSAFPQ
EVTGQMLLNFVSGGAAISVLARQLGAQLEVVDLGTVTPSLSLPGVRHLNIGPGTANFAKGAAMTRAQGELALQGGRDSVL
RAKAAGAQLFIGGEMGIGNTTAASALACALLDCPVVHLTGPGTGLNAEGVSHKAQVIERALALHAAQRGDALQTLFNLGG
FEIAALVGAYLACAQEGVAVLVDGFICTVAALVAVRLNPACREWLLFGHRGAEPGHRHVLETLGAEPLLELGLRLGEGSG
AALAVPLLRLACDLHGQMATFAEAAVADRPA
>Mature_350_residues
TQAWWLNPCKSVDTDAVENAAARQQQLTKPAGSLGRLESVAVQLAGLQGQVKPTLDHVWISIFAGDHGVVAEGVSAFPQE
VTGQMLLNFVSGGAAISVLARQLGAQLEVVDLGTVTPSLSLPGVRHLNIGPGTANFAKGAAMTRAQGELALQGGRDSVLR
AKAAGAQLFIGGEMGIGNTTAASALACALLDCPVVHLTGPGTGLNAEGVSHKAQVIERALALHAAQRGDALQTLFNLGGF
EIAALVGAYLACAQEGVAVLVDGFICTVAALVAVRLNPACREWLLFGHRGAEPGHRHVLETLGAEPLLELGLRLGEGSGA
ALAVPLLRLACDLHGQMATFAEAAVADRPA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=344, Percent_Identity=35.7558139534884, Blast_Score=200, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_PSEPF (Q3KFR5)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_347380.1
- ProteinModelPortal:   Q3KFR5
- SMR:   Q3KFR5
- STRING:   Q3KFR5
- GeneID:   3716782
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_1648
- eggNOG:   COG2038
- HOGENOM:   HBG634399
- OMA:   NEMATFS
- ProtClustDB:   PRK00105
- BioCyc:   PFLU205922:PFL_1648-MONOMER
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 35961; Mature: 35830

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: ACT_SITE 317-317

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAWWLNPCKSVDTDAVENAAARQQQLTKPAGSLGRLESVAVQLAGLQGQVKPTLDHVW
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHEE
ISIFAGDHGVVAEGVSAFPQEVTGQMLLNFVSGGAAISVLARQLGAQLEVVDLGTVTPSL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEECCCCCCC
SLPGVRHLNIGPGTANFAKGAAMTRAQGELALQGGRDSVLRAKAAGAQLFIGGEMGIGNT
CCCCCEEEECCCCCCHHHHCHHHHHCCCCEEEECCCHHHHHHHHCCCEEEECCCCCCCCH
TAASALACALLDCPVVHLTGPGTGLNAEGVSHKAQVIERALALHAAQRGDALQTLFNLGG
HHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
FEIAALVGAYLACAQEGVAVLVDGFICTVAALVAVRLNPACREWLLFGHRGAEPGHRHVL
HHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHH
ETLGAEPLLELGLRLGEGSGAALAVPLLRLACDLHGQMATFAEAAVADRPA
HHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TQAWWLNPCKSVDTDAVENAAARQQQLTKPAGSLGRLESVAVQLAGLQGQVKPTLDHVW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHEE
ISIFAGDHGVVAEGVSAFPQEVTGQMLLNFVSGGAAISVLARQLGAQLEVVDLGTVTPSL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEECCCCCCC
SLPGVRHLNIGPGTANFAKGAAMTRAQGELALQGGRDSVLRAKAAGAQLFIGGEMGIGNT
CCCCCEEEECCCCCCHHHHCHHHHHCCCCEEEECCCHHHHHHHHCCCEEEECCCCCCCCH
TAASALACALLDCPVVHLTGPGTGLNAEGVSHKAQVIERALALHAAQRGDALQTLFNLGG
HHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
FEIAALVGAYLACAQEGVAVLVDGFICTVAALVAVRLNPACREWLLFGHRGAEPGHRHVL
HHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHH
ETLGAEPLLELGLRLGEGSGAALAVPLLRLACDLHGQMATFAEAAVADRPA
HHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA