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The map label for this gene is cobU [H]

Identifier: 77457874

GI number: 77457874

Start: 1838340

End: 1838861

Strand: Direct

Name: cobU [H]

Synonym: Pfl01_1647

Alternate gene names: 77457874

Gene position: 1838340-1838861 (Clockwise)

Preceding gene: 77457873

Following gene: 77457875

Centisome position: 28.55

GC content: 63.22

Gene sequence:

>522_bases
ATGCTCCAGTTGATCCTCGGCGGCGCGCGCTCCGGCAAAAGTCGCCTGGCCGAAAAGCTCGCCACTGACAGCGCGCTGGC
CGTGACGTACATCGCCACCAGCCAGCCGCTGGATGGCGAGATGAATGAACGCGTCGCCCATCATCGCGCCCGCCGTCCTG
TCGAATGGGCGTTGATCGAAGAGCCGCTGGAACTGGCCCGTGTCCTGCGCGAAACCGCCAGCCCCGAACGTTGCCTGCTA
GTGGATTGCCTGACCCTCTGGCTGACCAATTTGCTGATGCTCGAAGACGCCGCACGTCTCGCCGCCGAACGCGAAGCCCT
GCTCGAATGCCTGGCGTCGCTGCCGGGTGAAATCATTTTTGTCAGCAACGAGACCGGAATGGGTGTCGTGCCGCTGGGCG
AATTGACTCGCCGCTACGTCGATGAAGCCGGTTGGCTGCATCAAGCTCTGGCCGAGGGTTGTCAGCGAGTCGTCCTGACG
GTCGCCGGCCTGCCTCTGACTCTGAAAGGACCTGCGTTATGA

Upstream 100 bases:

>100_bases
ATTACCACGGCCTGCGCGAACGCGATATCGAGCGGCTGGCGGATCTGGTGGAGAAGCACCTGGATACCGGGCTGTTACGT
GAACTCTGTGGAATCTCCCC

Downstream 100 bases:

>100_bases
CCCAAGCCTGGTGGCTGAACCCGTGCAAATCGGTGGATACGGACGCCGTTGAAAACGCGGCGGCGCGTCAGCAGCAATTG
ACCAAACCCGCCGGCTCTCT

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MLQLILGGARSGKSRLAEKLATDSALAVTYIATSQPLDGEMNERVAHHRARRPVEWALIEEPLELARVLRETASPERCLL
VDCLTLWLTNLLMLEDAARLAAEREALLECLASLPGEIIFVSNETGMGVVPLGELTRRYVDEAGWLHQALAEGCQRVVLT
VAGLPLTLKGPAL

Sequences:

>Translated_173_residues
MLQLILGGARSGKSRLAEKLATDSALAVTYIATSQPLDGEMNERVAHHRARRPVEWALIEEPLELARVLRETASPERCLL
VDCLTLWLTNLLMLEDAARLAAEREALLECLASLPGEIIFVSNETGMGVVPLGELTRRYVDEAGWLHQALAEGCQRVVLT
VAGLPLTLKGPAL
>Mature_173_residues
MLQLILGGARSGKSRLAEKLATDSALAVTYIATSQPLDGEMNERVAHHRARRPVEWALIEEPLELARVLRETASPERCLL
VDCLTLWLTNLLMLEDAARLAAEREALLECLASLPGEIIFVSNETGMGVVPLGELTRRYVDEAGWLHQALAEGCQRVVLT
VAGLPLTLKGPAL

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=184, Percent_Identity=38.5869565217391, Blast_Score=119, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18860; Mature: 18860

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLILGGARSGKSRLAEKLATDSALAVTYIATSQPLDGEMNERVAHHRARRPVEWALIE
CCEEEECCCCCCHHHHHHHHHCCCHHEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHH
EPLELARVLRETASPERCLLVDCLTLWLTNLLMLEDAARLAAEREALLECLASLPGEIIF
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VSNETGMGVVPLGELTRRYVDEAGWLHQALAEGCQRVVLTVAGLPLTLKGPAL
EECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
>Mature Secondary Structure
MLQLILGGARSGKSRLAEKLATDSALAVTYIATSQPLDGEMNERVAHHRARRPVEWALIE
CCEEEECCCCCCHHHHHHHHHCCCHHEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHH
EPLELARVLRETASPERCLLVDCLTLWLTNLLMLEDAARLAAEREALLECLASLPGEIIF
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VSNETGMGVVPLGELTRRYVDEAGWLHQALAEGCQRVVLTVAGLPLTLKGPAL
EECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]