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The map label for this gene is cobC [H]

Identifier: 77457876

GI number: 77457876

Start: 1839910

End: 1840485

Strand: Direct

Name: cobC [H]

Synonym: Pfl01_1649

Alternate gene names: 77457876

Gene position: 1839910-1840485 (Clockwise)

Preceding gene: 77457875

Following gene: 77457877

Centisome position: 28.58

GC content: 64.76

Gene sequence:

>576_bases
ATGACCTTGCGTCTGGACCTGCTGCGCCACGGTGAAACCGAACTCGGCGGCGGCCTGCGCGGCAGTCTCGACGATGCACT
GACCGAAAAGGGCTGGGCGCAGATGCGTGAGGCGGTGAGCGGGCAGGGGCCGTGGGACCGGCTGGTCAGTTCGCCGTTGC
AGCGTTGCGCGCGGTTTGCTGAAGAGTTGAGCGCGCAGCGGGATCTGCCGGTATCTCTGGACAAGAATCTTCAGGAGCTG
CATTTCGGTGCCTGGGAAGGGCAGAGCGCGGCGGCGTTGATGGAGACTGATGCTGAAGCGCTGGGGCTGTTCTGGGCGGA
TCCCTATGGCTTTACTCCGCCGCAGGGTGAGCCGGTCAGCGACTTCTCTGCGCGTGTGCTGGCGGCGGTCATGCGACTGC
ATGCAGCGCACGCGGGTGAGCGGGTGTTGCTGGTCAGCCATGGCGGCGTGATGCGTCTGCTGCTGGCGCGGGCCCGAGGT
TTGCCTCGCGAACAACTGCTCAATGTCGAAGTCGGTCATGGTGCGCTGTTTTCGCTGATCGTCGAAGCCGACGGTTCGCT
CAGGGAAGTGCTCTGA

Upstream 100 bases:

>100_bases
GCAGTGGCGCGGCGCTGGCGGTGCCGTTGCTGCGTCTGGCCTGTGACCTGCACGGGCAGATGGCGACCTTCGCCGAAGCC
GCGGTGGCGGACCGCCCGGC

Downstream 100 bases:

>100_bases
CATGCTGCCTCTGTGGATCGCCCTGCAATTTCTCGGCAGCCTGCCGATTCGTCTGCCGGGGATGCCGACGCCCGAACAGC
TTGGCCGGTCGCTGCTGTTT

Product: phosphoglycerate/bisphosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MTLRLDLLRHGETELGGGLRGSLDDALTEKGWAQMREAVSGQGPWDRLVSSPLQRCARFAEELSAQRDLPVSLDKNLQEL
HFGAWEGQSAAALMETDAEALGLFWADPYGFTPPQGEPVSDFSARVLAAVMRLHAAHAGERVLLVSHGGVMRLLLARARG
LPREQLLNVEVGHGALFSLIVEADGSLREVL

Sequences:

>Translated_191_residues
MTLRLDLLRHGETELGGGLRGSLDDALTEKGWAQMREAVSGQGPWDRLVSSPLQRCARFAEELSAQRDLPVSLDKNLQEL
HFGAWEGQSAAALMETDAEALGLFWADPYGFTPPQGEPVSDFSARVLAAVMRLHAAHAGERVLLVSHGGVMRLLLARARG
LPREQLLNVEVGHGALFSLIVEADGSLREVL
>Mature_190_residues
TLRLDLLRHGETELGGGLRGSLDDALTEKGWAQMREAVSGQGPWDRLVSSPLQRCARFAEELSAQRDLPVSLDKNLQELH
FGAWEGQSAAALMETDAEALGLFWADPYGFTPPQGEPVSDFSARVLAAVMRLHAAHAGERVLLVSHGGVMRLLLARARGL
PREQLLNVEVGHGALFSLIVEADGSLREVL

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=193, Percent_Identity=32.1243523316062, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 20743; Mature: 20612

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRLDLLRHGETELGGGLRGSLDDALTEKGWAQMREAVSGQGPWDRLVSSPLQRCARFA
CCEEEEHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EELSAQRDLPVSLDKNLQELHFGAWEGQSAAALMETDAEALGLFWADPYGFTPPQGEPVS
HHHHHCCCCCCCHHCCHHHHHCCCCCCCCHHHHHHCCHHHHHEEEECCCCCCCCCCCCCH
DFSARVLAAVMRLHAAHAGERVLLVSHGGVMRLLLARARGLPREQLLNVEVGHGALFSLI
HHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHH
VEADGSLREVL
HHCCCHHHHCC
>Mature Secondary Structure 
TLRLDLLRHGETELGGGLRGSLDDALTEKGWAQMREAVSGQGPWDRLVSSPLQRCARFA
CEEEEHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EELSAQRDLPVSLDKNLQELHFGAWEGQSAAALMETDAEALGLFWADPYGFTPPQGEPVS
HHHHHCCCCCCCHHCCHHHHHCCCCCCCCHHHHHHCCHHHHHEEEECCCCCCCCCCCCCH
DFSARVLAAVMRLHAAHAGERVLLVSHGGVMRLLLARARGLPREQLLNVEVGHGALFSLI
HHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHH
VEADGSLREVL
HHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]