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The map label for this gene is mreB [H]

Identifier: 77457065

GI number: 77457065

Start: 986267

End: 987304

Strand: Direct

Name: mreB [H]

Synonym: Pfl01_0838

Alternate gene names: 77457065

Gene position: 986267-987304 (Clockwise)

Preceding gene: 77457058

Following gene: 77457066

Centisome position: 15.32

GC content: 60.31

Gene sequence:

>1038_bases
ATGTTCAAGAAACTGCGTGGCATGTTTTCCAGCGATCTTTCCATTGACCTGGGCACTGCCAACACCCTTATTTACGTGCG
CGAGCGCGGTATCGTCCTGAATGAGCCATCGGTTGTGGCCATTCGGACACACGGTAACCAGAAAAGTGTCGTCGCTGTCG
GCACCGAGGCCAAGCGCATGCTCGGCCGTACGCCGGGCAACATTGCTGCCATTCGTCCGATGAAGGACGGCGTGATCGCC
GACTTCAGCGTCTGCGAAAAGATGCTGCAATACTTTATCAACAAGGTTCACGAAAACAGCTTTCTGCAGCCCAGCCCTCG
TGTGCTGATCTGCGTTCCATGCAAGTCCACCCAGGTTGAGCGTCGTGCCATCCGTGAATCGGCCCTTGGCGCCGGTGCCC
GTGAAGTGTTCCTGATCGAAGAGCCGATGGCGGCAGCGATCGGTGCCGGCCTGCCGGTTGAAGAAGCTCGCGGTTCGATG
GTCGTGGATATCGGTGGTGGTACCACCGAAATCGCGCTGATCTCCCTGAACGGTGTGGTCTATGCCGAGTCCGTACGTGT
TGGCGGCGACCGCTTCGACGAAGCGATCATCACCTACGTGCGCCGCAACTACGGCAGCCTGATCGGCGAATCCACCGCCG
AACGCATCAAGCAGGAAATCGGCACGGCCTACCCGGGCGGCGAAGTTCGCGAAGTCGACGTTCGCGGCCGTAACCTGGCC
GAAGGCGTTCCACGCGCATTCACCCTGAACTCCAACGAAGTGCTGGAAGCTCTGCAAGAGTCGCTGGCGACCATCGTTCA
GGCGGTGAAAAGTGCTCTGGAGCAATCGCCGCCGGAACTGGCTTCCGACATCGCCGAGCGTGGCCTGGTGCTGACCGGTG
GTGGCGCGCTGCTGCGTGACCTCGACAAGCTGCTGGCTCAGGAAACCGGTCTGCCGGTGATCGTTGCCGAAGATCCGCTG
ACCTGCGTCGCTCGCGGCGGTGGCCGTGCATTGGAAATGATGGACAAGCACACCATGGACCTGCTCTCCAGCGAATAA

Upstream 100 bases:

>100_bases
AAGCGGCCAATTTAACATATTGGCGCCTTGCCCAAAATCCCTGTCGTTGTTAGAGTTTGCCGCACTTTTTTACCCACGCG
TTGCCTAGGGTCCCTTTCCC

Downstream 100 bases:

>100_bases
TCGCCGGGTGCAATACGTGGGTGAGCGCACAGGCAGCACTTTGCAGTGCTGCCTGTTGGCGTTTATCTTCTGTCAGTCTT
CATCCAGGCCGGTTTGATGC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MFKKLRGMFSSDLSIDLGTANTLIYVRERGIVLNEPSVVAIRTHGNQKSVVAVGTEAKRMLGRTPGNIAAIRPMKDGVIA
DFSVCEKMLQYFINKVHENSFLQPSPRVLICVPCKSTQVERRAIRESALGAGAREVFLIEEPMAAAIGAGLPVEEARGSM
VVDIGGGTTEIALISLNGVVYAESVRVGGDRFDEAIITYVRRNYGSLIGESTAERIKQEIGTAYPGGEVREVDVRGRNLA
EGVPRAFTLNSNEVLEALQESLATIVQAVKSALEQSPPELASDIAERGLVLTGGGALLRDLDKLLAQETGLPVIVAEDPL
TCVARGGGRALEMMDKHTMDLLSSE

Sequences:

>Translated_345_residues
MFKKLRGMFSSDLSIDLGTANTLIYVRERGIVLNEPSVVAIRTHGNQKSVVAVGTEAKRMLGRTPGNIAAIRPMKDGVIA
DFSVCEKMLQYFINKVHENSFLQPSPRVLICVPCKSTQVERRAIRESALGAGAREVFLIEEPMAAAIGAGLPVEEARGSM
VVDIGGGTTEIALISLNGVVYAESVRVGGDRFDEAIITYVRRNYGSLIGESTAERIKQEIGTAYPGGEVREVDVRGRNLA
EGVPRAFTLNSNEVLEALQESLATIVQAVKSALEQSPPELASDIAERGLVLTGGGALLRDLDKLLAQETGLPVIVAEDPL
TCVARGGGRALEMMDKHTMDLLSSE
>Mature_345_residues
MFKKLRGMFSSDLSIDLGTANTLIYVRERGIVLNEPSVVAIRTHGNQKSVVAVGTEAKRMLGRTPGNIAAIRPMKDGVIA
DFSVCEKMLQYFINKVHENSFLQPSPRVLICVPCKSTQVERRAIRESALGAGAREVFLIEEPMAAAIGAGLPVEEARGSM
VVDIGGGTTEIALISLNGVVYAESVRVGGDRFDEAIITYVRRNYGSLIGESTAERIKQEIGTAYPGGEVREVDVRGRNLA
EGVPRAFTLNSNEVLEALQESLATIVQAVKSALEQSPPELASDIAERGLVLTGGGALLRDLDKLLAQETGLPVIVAEDPL
TCVARGGGRALEMMDKHTMDLLSSE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=347, Percent_Identity=80.6916426512968, Blast_Score=564, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37004; Mature: 37004

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLRGMFSSDLSIDLGTANTLIYVRERGIVLNEPSVVAIRTHGNQKSVVAVGTEAKRM
CCHHHHHHHCCCCEEEECCCCEEEEEEECCEEECCCCEEEEEECCCCCCEEEECCHHHHH
LGRTPGNIAAIRPMKDGVIADFSVCEKMLQYFINKVHENSFLQPSPRVLICVPCKSTQVE
HCCCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHH
RRAIRESALGAGAREVFLIEEPMAAAIGAGLPVEEARGSMVVDIGGGTTEIALISLNGVV
HHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCHHHCCCCEEEEECCCCEEEEEEEECCEE
YAESVRVGGDRFDEAIITYVRRNYGSLIGESTAERIKQEIGTAYPGGEVREVDVRGRNLA
EEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHH
EGVPRAFTLNSNEVLEALQESLATIVQAVKSALEQSPPELASDIAERGLVLTGGGALLRD
HCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHHHHH
LDKLLAQETGLPVIVAEDPLTCVARGGGRALEMMDKHTMDLLSSE
HHHHHHHHCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKKLRGMFSSDLSIDLGTANTLIYVRERGIVLNEPSVVAIRTHGNQKSVVAVGTEAKRM
CCHHHHHHHCCCCEEEECCCCEEEEEEECCEEECCCCEEEEEECCCCCCEEEECCHHHHH
LGRTPGNIAAIRPMKDGVIADFSVCEKMLQYFINKVHENSFLQPSPRVLICVPCKSTQVE
HCCCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHH
RRAIRESALGAGAREVFLIEEPMAAAIGAGLPVEEARGSMVVDIGGGTTEIALISLNGVV
HHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCHHHCCCCEEEEECCCCEEEEEEEECCEE
YAESVRVGGDRFDEAIITYVRRNYGSLIGESTAERIKQEIGTAYPGGEVREVDVRGRNLA
EEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHH
EGVPRAFTLNSNEVLEALQESLATIVQAVKSALEQSPPELASDIAERGLVLTGGGALLRD
HCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHHHHH
LDKLLAQETGLPVIVAEDPLTCVARGGGRALEMMDKHTMDLLSSE
HHHHHHHHCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]