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The map label for this gene is yxlA [H]

Identifier: 77456721

GI number: 77456721

Start: 572127

End: 573419

Strand: Direct

Name: yxlA [H]

Synonym: Pfl01_0493

Alternate gene names: 77456721

Gene position: 572127-573419 (Clockwise)

Preceding gene: 77456720

Following gene: 77456723

Centisome position: 8.89

GC content: 63.73

Gene sequence:

>1293_bases
TTGAGCACTCAACCCGGTACTTATTCCCCCGACCTCGCCGTGCCCGCCAACCAGCGTGTATTCGGCGGTCGCGATCTGTT
TTCCCTGTGGTTTTCCCTCGGCATCGGCCTGATGGTCTTGCAGACCGGTGCATTGCTGGCGCCGGGGCTGGGCCTGTCGG
GATCGCTGCTGGCGATTTTCCTCGGCACCCTGGTCGGCGTCCTGTTGCTGGCCGCCGTTGGCGTGATCGGCAGCGACACC
GGCCTGTCGTCGATGGCCGCGCTGAAACTCAGCCTCGGCAGCAAAGGTGCGAGCCTGCCGGCGCTGCTCAACCTGCTGCA
ACTGATCGGATGGGGCTCGTTCGAAATTATCGTCATGCGCGACGCCGCCAGTCTGCTCGGCACCCGTGCGTTCAGCGAAG
GTTCGCTGTGGGCCAGTCCGATGTTGTGGACGCTGTGCTTCGGCGCATTGGCGACGTTGCTCGCGATCAGCGGGCCGTTG
ACGTTCGTGCGCAAGATCCTGCGCAAGTGGGGCATCTGGCTGATTCTGGCCGCGTGCATCTGGCTGACCTGGAACCTGTT
CGCCAAGGCTGATCTCGCCGCCTTGTGGGCACAGGCCGGGGATGGCTCGATGTCACTCGCCGTGGGCTTCGACATTGCGA
TTGCGATGCCGCTGTCGTGGCTGCCGCTGATCGCCGACTACTCGCGTTTCGGCCAGCGGGCGAAGAACGTGTTCGGCGGC
ACGGCCATCGGGTTTTTCATCGGCAACTTCTGGCTGATGAGTCTCGGCGTGGCCTACACCCTGGCCTTCGCGCCGAGCGG
TGAAGTCAACGCGCTGCTGCTGGCACTGGCCGGTGCGGGTCTGGGTATTCCGCTGCTGCTGATTCTGCTGGACGAGTCGG
AGAACGCTTTCGCCGACATTCATTCGGCAGCGGTTTCCAGCGGGATTCTGTTGCGTCTGAAAGTCGAGCATCTGGCGCTG
GCCATCGGTGTGATCTGCACCCTGATCGCCTTGCTCGCGCCATTGGCGCAATACCAGAACTTCCTGCTGCTGATCGGTTC
GGTGTTTGCACCGCTGTTCGGCGTGGTGCTGGTGGATCACTTCATCCTGCGCAAACGCAGTGCCCAAGTGGCGTCGGCCG
CGTTGCGCTGGCCGGCACTATTGGCCTGGCTGGGTGGCATCAGCACCTATCACTTGCTGGCCAATCTGTATCCGGATGTC
GGCGCGACCCTGCCGGCGCTGGTGCTGGCAGGGCTGCTGCAACTGGTGCTCGGCCGGGCTTTCAGTTACGGCCGGGAAAC
AGCTCGGGCTTGA

Upstream 100 bases:

>100_bases
CGTCTAGGCGTCGGACCGTCCGCACCGATCGTTCCCACGCAGAGCGTGGGAACGATCAACGGGTCAGCACAACAACAAAT
GTCCCTCTGAGATAACACCC

Downstream 100 bases:

>100_bases
GAATGCCGTTCAGGCGCGGGTAAGGGATCTTCAGTTCGACGTGGCCCAGCGCATAAGGCGCGATGGTGGTCACGTCGTAC
TTGAGGATCACACCGCCGTA

Product: cytosine/purines, uracil, thiamine, allantoin permease

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MSTQPGTYSPDLAVPANQRVFGGRDLFSLWFSLGIGLMVLQTGALLAPGLGLSGSLLAIFLGTLVGVLLLAAVGVIGSDT
GLSSMAALKLSLGSKGASLPALLNLLQLIGWGSFEIIVMRDAASLLGTRAFSEGSLWASPMLWTLCFGALATLLAISGPL
TFVRKILRKWGIWLILAACIWLTWNLFAKADLAALWAQAGDGSMSLAVGFDIAIAMPLSWLPLIADYSRFGQRAKNVFGG
TAIGFFIGNFWLMSLGVAYTLAFAPSGEVNALLLALAGAGLGIPLLLILLDESENAFADIHSAAVSSGILLRLKVEHLAL
AIGVICTLIALLAPLAQYQNFLLLIGSVFAPLFGVVLVDHFILRKRSAQVASAALRWPALLAWLGGISTYHLLANLYPDV
GATLPALVLAGLLQLVLGRAFSYGRETARA

Sequences:

>Translated_430_residues
MSTQPGTYSPDLAVPANQRVFGGRDLFSLWFSLGIGLMVLQTGALLAPGLGLSGSLLAIFLGTLVGVLLLAAVGVIGSDT
GLSSMAALKLSLGSKGASLPALLNLLQLIGWGSFEIIVMRDAASLLGTRAFSEGSLWASPMLWTLCFGALATLLAISGPL
TFVRKILRKWGIWLILAACIWLTWNLFAKADLAALWAQAGDGSMSLAVGFDIAIAMPLSWLPLIADYSRFGQRAKNVFGG
TAIGFFIGNFWLMSLGVAYTLAFAPSGEVNALLLALAGAGLGIPLLLILLDESENAFADIHSAAVSSGILLRLKVEHLAL
AIGVICTLIALLAPLAQYQNFLLLIGSVFAPLFGVVLVDHFILRKRSAQVASAALRWPALLAWLGGISTYHLLANLYPDV
GATLPALVLAGLLQLVLGRAFSYGRETARA
>Mature_429_residues
STQPGTYSPDLAVPANQRVFGGRDLFSLWFSLGIGLMVLQTGALLAPGLGLSGSLLAIFLGTLVGVLLLAAVGVIGSDTG
LSSMAALKLSLGSKGASLPALLNLLQLIGWGSFEIIVMRDAASLLGTRAFSEGSLWASPMLWTLCFGALATLLAISGPLT
FVRKILRKWGIWLILAACIWLTWNLFAKADLAALWAQAGDGSMSLAVGFDIAIAMPLSWLPLIADYSRFGQRAKNVFGGT
AIGFFIGNFWLMSLGVAYTLAFAPSGEVNALLLALAGAGLGIPLLLILLDESENAFADIHSAAVSSGILLRLKVEHLALA
IGVICTLIALLAPLAQYQNFLLLIGSVFAPLFGVVLVDHFILRKRSAQVASAALRWPALLAWLGGISTYHLLANLYPDVG
ATLPALVLAGLLQLVLGRAFSYGRETARA

Specific function: Required For Cytosine Transport Into The Cell. [C]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 45157; Mature: 45026

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQPGTYSPDLAVPANQRVFGGRDLFSLWFSLGIGLMVLQTGALLAPGLGLSGSLLAIF
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHH
LGTLVGVLLLAAVGVIGSDTGLSSMAALKLSLGSKGASLPALLNLLQLIGWGSFEIIVMR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEE
DAASLLGTRAFSEGSLWASPMLWTLCFGALATLLAISGPLTFVRKILRKWGIWLILAACI
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
WLTWNLFAKADLAALWAQAGDGSMSLAVGFDIAIAMPLSWLPLIADYSRFGQRAKNVFGG
HHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
TAIGFFIGNFWLMSLGVAYTLAFAPSGEVNALLLALAGAGLGIPLLLILLDESENAFADI
HHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
HSAAVSSGILLRLKVEHLALAIGVICTLIALLAPLAQYQNFLLLIGSVFAPLFGVVLVDH
HHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILRKRSAQVASAALRWPALLAWLGGISTYHLLANLYPDVGATLPALVLAGLLQLVLGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FSYGRETARA
HHHHHHHCCC
>Mature Secondary Structure 
STQPGTYSPDLAVPANQRVFGGRDLFSLWFSLGIGLMVLQTGALLAPGLGLSGSLLAIF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHH
LGTLVGVLLLAAVGVIGSDTGLSSMAALKLSLGSKGASLPALLNLLQLIGWGSFEIIVMR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEE
DAASLLGTRAFSEGSLWASPMLWTLCFGALATLLAISGPLTFVRKILRKWGIWLILAACI
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
WLTWNLFAKADLAALWAQAGDGSMSLAVGFDIAIAMPLSWLPLIADYSRFGQRAKNVFGG
HHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
TAIGFFIGNFWLMSLGVAYTLAFAPSGEVNALLLALAGAGLGIPLLLILLDESENAFADI
HHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
HSAAVSSGILLRLKVEHLALAIGVICTLIALLAPLAQYQNFLLLIGSVFAPLFGVVLVDH
HHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILRKRSAQVASAALRWPALLAWLGGISTYHLLANLYPDVGATLPALVLAGLLQLVLGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FSYGRETARA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]