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The map label for this gene is lgrD [H]

Identifier: 77456354

GI number: 77456354

Start: 135065

End: 138454

Strand: Reverse

Name: lgrD [H]

Synonym: Pfl01_0126

Alternate gene names: 77456354

Gene position: 138454-135065 (Counterclockwise)

Preceding gene: 77456355

Following gene: 77456353

Centisome position: 2.15

GC content: 63.07

Gene sequence:

>3390_bases
ATGAGACGTCTCGACATTTTGCTGAGGGGCCGCAGCCAGGCCTTGACCGACCTGGCGCAGGAGCTCGAACAACACGGTCA
TTCATTGCTGACAGAAACCGCTCCGTCGATGGACCTGGTGATCGATGACGGCAGCCTTGCGCCGCAGGATCATGGCACGA
CACCGTACCTGACCTTGCGTCTGGGCATCGGTGCAACGGGCGCCGGCGGTTTGCCGGTGCTTGATCTGCTGTGCCTGTGC
AACTCGACGCTGCTGAGCCGCGTGCCCATCGCCGACGAACCGTCCGGCAACGGTCAGGCCCTGCGCCAGCGAGCACTGGC
GCAGGTGGTGGACGAAGTGGCGCTGCTGGTCAGTCGTTTTTCCCGCGATGCCGAGTATTTCCAGCACGCAGAGACGGCTC
GTGCGCCGGACTTCGAGCAGGTGGAAAACCTGCTGTTTCTCGACAGCCTGGCTTATGTCCATCGCTTCAATGCCACGGCC
AATCCGGCGTTGTTGCAACAGGCGCAGATCCCGGTGATCGAGCGGCTGCAACGGAGCCTGATCGAACACGCGGAACGCCC
GGCACTGCACCTCGCAGAGCAGTCGATCAGCTATCGCCAGTTGCATGATCACAGCCGGGCGATCCAGCAACGGTTGCTGG
CAATGCTGGAGGCACAACCGCAACCGTGGGTGGTGGGGATTTGCCTGCCGAAATGCGATGCGCTGTTTGCTTCTATCCTG
GCCATTCTCGGCAGCGGCGCGGTGTACCTGCCGCTGGAACCGAGCCATCCGCTTCAGCGCCAGCAGTACATTCTGGAAAA
CGCCGGGGCGGTGCTGTTGCTGCACGACGGCGAACACCCGCTGAGCGGTTCGATGCCGGGGCTGGATGTCTGTCGCATCG
ACAGCACCGACGCCGATCTGTCGCAACCGTTGATGCACCACCGGCCCGAGCTCGACACGCCGTGCATGGCGCTCTACACC
TCGGGCACCACCGGGCATCCGAAGGGTGTGCTGCTCAGTCAGGCAAACCTCGCGCACTTCACCGCGTGGTACGCCGACTA
TGTGCAGTTGCACGCCGAGAGTCGGGTGTTGCAGTTCTCGTCGCTGAGTTTTGACTCGTCGCTGATCGATATTTTCCCGA
CCCTGCTCGAAGGCGCGGAACTGGTAGTGCCCGATGACAACCAGCGCCGCGATCCGCTGCAACTGGTGGCGCTGATCCGC
CGCCGGCAACTGACCCACGCGTTCCTGCCGCCGGCGCTGTTGAGCATCCTGCCGCTGGAGCAACTGCAAAGCGTCGGACA
GATCATGACCGGCGGCGACGTGTGTGAACCGTTCGTGATCGAGCAACTGACGCGTCAGGGCAAGCTGCACAACCTCTACG
GCCCGACCGAAGCCACGGTGCTGATCACCGCGCGGCAACTGCAACCGGGCGACAGCAATCGCACCCTCGGCGGGCCGATT
GCCAACAGTCAGGTGCTGATCCTCGATGACGACCTGCAACCGGTGCCGGAGCAAACGGTGGGCGAGCTGTTCATCGTCGG
TCCCGGCGTATGCCTGGGTTACCTGAACAACCCACAGCAGACGGCGGAGCGCTATCTGGATCTGGAATTGCCTGACGGCC
AACGTCTGCGCGCCTACCGCAGCGGCGACATGGCCAAGTGGGGCGAGGATGGCATCGAGCTGTGCGGACGCCGCGACAAT
CAGGTGAAGATCCGCGGCTTCCGGGTCGAGCCGGAAGAAATCGAGCGGTGCCTGCGCGAGAGCCAGCTGTATCGGCAGAT
CGCCGTGGTGATCGACAGTCAGCGGCGAATTCTGGCGTTCCTCGCCCAGCCGCAATCGGATGCCGCACGGGAGACTTTGA
AAGCTCACGCGCAGCAGTTTTTGCCCGACTACATGCAACCGGTGGCATGGACGGAACTGCCGAACATGCCATTCGCCGCC
AACGGCAAAGTCGACCGTAAGGCGCTGCTGGAACTGCCGGTCAGCGTGCAGGACAGCGGCCCGAAATGCCTGCCGGCCAA
CGCCGACGAAGCGCTGCTGCTGGAAATCTGGGGCGAGTTGCTGGAGCTGCCGATCAGCGACATTTCCACCGACGAAAGCT
TCTTCAATCTCGGCGGTCACTCGATTCTGCTGTCACGCATGCTCCTGCGTCTGCGGGAAGAGTTCGGCCGCAGCATTTCG
ATCAACCGCTTCATTGAACTGCCGACCATCACCAAGCTCGCCACCCTGGTACGCGGCACCGATGACAGCGCGGTGCTCAG
CGCCCAGGCGATGGCCGACGCCGAGCGACCATTGGAAATTGAGCCATTGCCGATCAGCCGCATGGGCGATGTGCACAAGG
TGATCGTCACCGGCGCCAACAGTTTTGTCGGTGTGCACATCGTCGAGGCGCTGCTGGGATGGGGCGCCAGCGAGGTGGCG
TGTCTGGTGCGCGACGGCGGCGGGCAAACCGCGGCGCAGCGCTTTGCCCAATCGTTGCGAGAGAACCGGCTGGAGCATCT
GGACCTGAGTCGGGTGCGGATCTATTCGGCAGACATTACACAGCCGCAACTGGGCCTGGCTGATGGGGACTTCGAGCGAC
TGGATCGCGAGTTCGGCGCGCTGGTACACAACGCCGCCAACGTCAATCACGTGCTCGATTACGAGTCGCTGGCGGCGGAC
AACGTCGAGCCGATTTTCGAACTGGTGCGGCTGTGCGAAGGGCGCAGCAAGAAGGTGTTCAATTTCGTCTCGACGCTGTC
GGCGTCCAGTACCGTCGACGACGCAGGCCGGGTGCTGGAATTGCCCGCCGCACCGACGCCGCCGATCTACATCCGCAACG
GCTACAACCTGTCGAAGTGGGTCGGTGAACGCATCCTCGAACGGGCGCGGGAACGCGGGGTGCGGGTCAATCTTTATCGG
CCCGGCAACATCAGTTTCAACAGCCTCAGCGGCGTCTGCCAGCCGCACAAGAACCGTTTGATGCTGATGCTCAAGGGCTC
GATCCAGCTCGGTCAGGTGCCGGCCTTCGCGCTGAATTTCGACCTGATGCCGGTGGACTTCCTCGCCCGTTTCATCGCCT
TCCACGCCAGCCGTTATTCGCCGGAACGAGCGGTATTCAACCTGCACAACCCGGAACCCCTGAGCTGGGATGCCTACGTC
GCGTCGTTTCGCGAAACCGGCAGCGAATTTTCACTGGTGAGCGTCGCCGACTGGCAACAGCAACTGGGCCGGGTCGACGC
CGACAACGCGCTGTTCGGCGTGCTCGGTTTCTACCTCAACGGCTTCGAGGAAGACATCGGCGACATCTCCCTGATCGGCC
ACGCCAACGCCCAGGCCGGCGTGCAGCAGATGGGCGCGCACTACCCGGAAAAATCCCCGGCGCTGCTGCGTCGCGGCTGC
GACTACCTGAAAGAAATCAACTTCATCTGA

Upstream 100 bases:

>100_bases
GTGGGCAACATCGTGCGCTTTTTCCACAACAGCTCACTGCTCGACACTCCGTGCGTGCAGCACGCCCTGCGCGACTACCT
GGTTTGACAAGGAGGCTGAC

Downstream 100 bases:

>100_bases
CTCATCAACCAAGGAGCAACACCATGAGCAATCTGCAACCCGACACCCTGATCAAAAACCCTCACGGCTGCCACGTCGTG
TCTTCGGTGGAAGTGCCGGT

Product: amino acid adenylation:thioester reductase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1129; Mature: 1129

Protein sequence:

>1129_residues
MRRLDILLRGRSQALTDLAQELEQHGHSLLTETAPSMDLVIDDGSLAPQDHGTTPYLTLRLGIGATGAGGLPVLDLLCLC
NSTLLSRVPIADEPSGNGQALRQRALAQVVDEVALLVSRFSRDAEYFQHAETARAPDFEQVENLLFLDSLAYVHRFNATA
NPALLQQAQIPVIERLQRSLIEHAERPALHLAEQSISYRQLHDHSRAIQQRLLAMLEAQPQPWVVGICLPKCDALFASIL
AILGSGAVYLPLEPSHPLQRQQYILENAGAVLLLHDGEHPLSGSMPGLDVCRIDSTDADLSQPLMHHRPELDTPCMALYT
SGTTGHPKGVLLSQANLAHFTAWYADYVQLHAESRVLQFSSLSFDSSLIDIFPTLLEGAELVVPDDNQRRDPLQLVALIR
RRQLTHAFLPPALLSILPLEQLQSVGQIMTGGDVCEPFVIEQLTRQGKLHNLYGPTEATVLITARQLQPGDSNRTLGGPI
ANSQVLILDDDLQPVPEQTVGELFIVGPGVCLGYLNNPQQTAERYLDLELPDGQRLRAYRSGDMAKWGEDGIELCGRRDN
QVKIRGFRVEPEEIERCLRESQLYRQIAVVIDSQRRILAFLAQPQSDAARETLKAHAQQFLPDYMQPVAWTELPNMPFAA
NGKVDRKALLELPVSVQDSGPKCLPANADEALLLEIWGELLELPISDISTDESFFNLGGHSILLSRMLLRLREEFGRSIS
INRFIELPTITKLATLVRGTDDSAVLSAQAMADAERPLEIEPLPISRMGDVHKVIVTGANSFVGVHIVEALLGWGASEVA
CLVRDGGGQTAAQRFAQSLRENRLEHLDLSRVRIYSADITQPQLGLADGDFERLDREFGALVHNAANVNHVLDYESLAAD
NVEPIFELVRLCEGRSKKVFNFVSTLSASSTVDDAGRVLELPAAPTPPIYIRNGYNLSKWVGERILERARERGVRVNLYR
PGNISFNSLSGVCQPHKNRLMLMLKGSIQLGQVPAFALNFDLMPVDFLARFIAFHASRYSPERAVFNLHNPEPLSWDAYV
ASFRETGSEFSLVSVADWQQQLGRVDADNALFGVLGFYLNGFEEDIGDISLIGHANAQAGVQQMGAHYPEKSPALLRRGC
DYLKEINFI

Sequences:

>Translated_1129_residues
MRRLDILLRGRSQALTDLAQELEQHGHSLLTETAPSMDLVIDDGSLAPQDHGTTPYLTLRLGIGATGAGGLPVLDLLCLC
NSTLLSRVPIADEPSGNGQALRQRALAQVVDEVALLVSRFSRDAEYFQHAETARAPDFEQVENLLFLDSLAYVHRFNATA
NPALLQQAQIPVIERLQRSLIEHAERPALHLAEQSISYRQLHDHSRAIQQRLLAMLEAQPQPWVVGICLPKCDALFASIL
AILGSGAVYLPLEPSHPLQRQQYILENAGAVLLLHDGEHPLSGSMPGLDVCRIDSTDADLSQPLMHHRPELDTPCMALYT
SGTTGHPKGVLLSQANLAHFTAWYADYVQLHAESRVLQFSSLSFDSSLIDIFPTLLEGAELVVPDDNQRRDPLQLVALIR
RRQLTHAFLPPALLSILPLEQLQSVGQIMTGGDVCEPFVIEQLTRQGKLHNLYGPTEATVLITARQLQPGDSNRTLGGPI
ANSQVLILDDDLQPVPEQTVGELFIVGPGVCLGYLNNPQQTAERYLDLELPDGQRLRAYRSGDMAKWGEDGIELCGRRDN
QVKIRGFRVEPEEIERCLRESQLYRQIAVVIDSQRRILAFLAQPQSDAARETLKAHAQQFLPDYMQPVAWTELPNMPFAA
NGKVDRKALLELPVSVQDSGPKCLPANADEALLLEIWGELLELPISDISTDESFFNLGGHSILLSRMLLRLREEFGRSIS
INRFIELPTITKLATLVRGTDDSAVLSAQAMADAERPLEIEPLPISRMGDVHKVIVTGANSFVGVHIVEALLGWGASEVA
CLVRDGGGQTAAQRFAQSLRENRLEHLDLSRVRIYSADITQPQLGLADGDFERLDREFGALVHNAANVNHVLDYESLAAD
NVEPIFELVRLCEGRSKKVFNFVSTLSASSTVDDAGRVLELPAAPTPPIYIRNGYNLSKWVGERILERARERGVRVNLYR
PGNISFNSLSGVCQPHKNRLMLMLKGSIQLGQVPAFALNFDLMPVDFLARFIAFHASRYSPERAVFNLHNPEPLSWDAYV
ASFRETGSEFSLVSVADWQQQLGRVDADNALFGVLGFYLNGFEEDIGDISLIGHANAQAGVQQMGAHYPEKSPALLRRGC
DYLKEINFI
>Mature_1129_residues
MRRLDILLRGRSQALTDLAQELEQHGHSLLTETAPSMDLVIDDGSLAPQDHGTTPYLTLRLGIGATGAGGLPVLDLLCLC
NSTLLSRVPIADEPSGNGQALRQRALAQVVDEVALLVSRFSRDAEYFQHAETARAPDFEQVENLLFLDSLAYVHRFNATA
NPALLQQAQIPVIERLQRSLIEHAERPALHLAEQSISYRQLHDHSRAIQQRLLAMLEAQPQPWVVGICLPKCDALFASIL
AILGSGAVYLPLEPSHPLQRQQYILENAGAVLLLHDGEHPLSGSMPGLDVCRIDSTDADLSQPLMHHRPELDTPCMALYT
SGTTGHPKGVLLSQANLAHFTAWYADYVQLHAESRVLQFSSLSFDSSLIDIFPTLLEGAELVVPDDNQRRDPLQLVALIR
RRQLTHAFLPPALLSILPLEQLQSVGQIMTGGDVCEPFVIEQLTRQGKLHNLYGPTEATVLITARQLQPGDSNRTLGGPI
ANSQVLILDDDLQPVPEQTVGELFIVGPGVCLGYLNNPQQTAERYLDLELPDGQRLRAYRSGDMAKWGEDGIELCGRRDN
QVKIRGFRVEPEEIERCLRESQLYRQIAVVIDSQRRILAFLAQPQSDAARETLKAHAQQFLPDYMQPVAWTELPNMPFAA
NGKVDRKALLELPVSVQDSGPKCLPANADEALLLEIWGELLELPISDISTDESFFNLGGHSILLSRMLLRLREEFGRSIS
INRFIELPTITKLATLVRGTDDSAVLSAQAMADAERPLEIEPLPISRMGDVHKVIVTGANSFVGVHIVEALLGWGASEVA
CLVRDGGGQTAAQRFAQSLRENRLEHLDLSRVRIYSADITQPQLGLADGDFERLDREFGALVHNAANVNHVLDYESLAAD
NVEPIFELVRLCEGRSKKVFNFVSTLSASSTVDDAGRVLELPAAPTPPIYIRNGYNLSKWVGERILERARERGVRVNLYR
PGNISFNSLSGVCQPHKNRLMLMLKGSIQLGQVPAFALNFDLMPVDFLARFIAFHASRYSPERAVFNLHNPEPLSWDAYV
ASFRETGSEFSLVSVADWQQQLGRVDADNALFGVLGFYLNGFEEDIGDISLIGHANAQAGVQQMGAHYPEKSPALLRRGC
DYLKEINFI

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=437, Percent_Identity=25.629290617849, Blast_Score=91, Evalue=9e-18,
Organism=Escherichia coli, GI1786801, Length=620, Percent_Identity=31.4516129032258, Blast_Score=228, Evalue=2e-60,
Organism=Escherichia coli, GI1788107, Length=539, Percent_Identity=23.191094619666, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17556356, Length=618, Percent_Identity=24.7572815533981, Blast_Score=157, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17550940, Length=632, Percent_Identity=22.3101265822785, Blast_Score=126, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI32564420, Length=414, Percent_Identity=24.8792270531401, Blast_Score=100, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI32564422, Length=414, Percent_Identity=24.8792270531401, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17560308, Length=359, Percent_Identity=25.6267409470752, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17559526, Length=363, Percent_Identity=27.5482093663912, Blast_Score=77, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17538037, Length=372, Percent_Identity=24.4623655913978, Blast_Score=73, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319591, Length=1058, Percent_Identity=24.1020793950851, Blast_Score=241, Evalue=5e-64,
Organism=Drosophila melanogaster, GI24648676, Length=685, Percent_Identity=27.5912408759124, Blast_Score=176, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24581924, Length=363, Percent_Identity=24.7933884297521, Blast_Score=81, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 124803; Mature: 124803

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50075 ACP_DOMAIN ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLDILLRGRSQALTDLAQELEQHGHSLLTETAPSMDLVIDDGSLAPQDHGTTPYLTLR
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEE
LGIGATGAGGLPVLDLLCLCNSTLLSRVPIADEPSGNGQALRQRALAQVVDEVALLVSRF
EECCCCCCCCHHHHHHHHHHCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRDAEYFQHAETARAPDFEQVENLLFLDSLAYVHRFNATANPALLQQAQIPVIERLQRSL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHH
IEHAERPALHLAEQSISYRQLHDHSRAIQQRLLAMLEAQPQPWVVGICLPKCDALFASIL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
AILGSGAVYLPLEPSHPLQRQQYILENAGAVLLLHDGEHPLSGSMPGLDVCRIDSTDADL
HHHCCCCEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCHH
SQPLMHHRPELDTPCMALYTSGTTGHPKGVLLSQANLAHFTAWYADYVQLHAESRVLQFS
HHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHEEEEE
SLSFDSSLIDIFPTLLEGAELVVPDDNQRRDPLQLVALIRRRQLTHAFLPPALLSILPLE
CCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCHH
QLQSVGQIMTGGDVCEPFVIEQLTRQGKLHNLYGPTEATVLITARQLQPGDSNRTLGGPI
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCC
ANSQVLILDDDLQPVPEQTVGELFIVGPGVCLGYLNNPQQTAERYLDLELPDGQRLRAYR
CCCEEEEEECCCCCCCCHHHCCEEEECCCEEEECCCCHHHHHHHHEECCCCCCHHHHHHH
SGDMAKWGEDGIELCGRRDNQVKIRGFRVEPEEIERCLRESQLYRQIAVVIDSQRRILAF
CCCCCCCCCHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LAQPQSDAARETLKAHAQQFLPDYMQPVAWTELPNMPFAANGKVDRKALLELPVSVQDSG
HCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHCCCEECCCC
PKCLPANADEALLLEIWGELLELPISDISTDESFFNLGGHSILLSRMLLRLREEFGRSIS
CEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCEE
INRFIELPTITKLATLVRGTDDSAVLSAQAMADAERPLEIEPLPISRMGDVHKVIVTGAN
ECCEEECCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEECCCCCHHCCCCEEEEEECCC
SFVGVHIVEALLGWGASEVACLVRDGGGQTAAQRFAQSLRENRLEHLDLSRVRIYSADIT
CHHHHHHHHHHHCCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
QPQLGLADGDFERLDREFGALVHNAANVNHVLDYESLAADNVEPIFELVRLCEGRSKKVF
CCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCHHHHCCCCHHHHHHHHHHHCCCCHHHH
NFVSTLSASSTVDDAGRVLELPAAPTPPIYIRNGYNLSKWVGERILERARERGVRVNLYR
HHHHHHCCCCCCCCCCCEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEC
PGNISFNSLSGVCQPHKNRLMLMLKGSIQLGQVPAFALNFDLMPVDFLARFIAFHASRYS
CCCCCHHHHCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCHHHHHHHHHHHHHCCC
PERAVFNLHNPEPLSWDAYVASFRETGSEFSLVSVADWQQQLGRVDADNALFGVLGFYLN
CCCCEEECCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHH
GFEEDIGDISLIGHANAQAGVQQMGAHYPEKSPALLRRGCDYLKEINFI
HHHHCCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRLDILLRGRSQALTDLAQELEQHGHSLLTETAPSMDLVIDDGSLAPQDHGTTPYLTLR
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEE
LGIGATGAGGLPVLDLLCLCNSTLLSRVPIADEPSGNGQALRQRALAQVVDEVALLVSRF
EECCCCCCCCHHHHHHHHHHCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRDAEYFQHAETARAPDFEQVENLLFLDSLAYVHRFNATANPALLQQAQIPVIERLQRSL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHH
IEHAERPALHLAEQSISYRQLHDHSRAIQQRLLAMLEAQPQPWVVGICLPKCDALFASIL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
AILGSGAVYLPLEPSHPLQRQQYILENAGAVLLLHDGEHPLSGSMPGLDVCRIDSTDADL
HHHCCCCEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCHH
SQPLMHHRPELDTPCMALYTSGTTGHPKGVLLSQANLAHFTAWYADYVQLHAESRVLQFS
HHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHEEEEE
SLSFDSSLIDIFPTLLEGAELVVPDDNQRRDPLQLVALIRRRQLTHAFLPPALLSILPLE
CCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCHH
QLQSVGQIMTGGDVCEPFVIEQLTRQGKLHNLYGPTEATVLITARQLQPGDSNRTLGGPI
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCC
ANSQVLILDDDLQPVPEQTVGELFIVGPGVCLGYLNNPQQTAERYLDLELPDGQRLRAYR
CCCEEEEEECCCCCCCCHHHCCEEEECCCEEEECCCCHHHHHHHHEECCCCCCHHHHHHH
SGDMAKWGEDGIELCGRRDNQVKIRGFRVEPEEIERCLRESQLYRQIAVVIDSQRRILAF
CCCCCCCCCHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LAQPQSDAARETLKAHAQQFLPDYMQPVAWTELPNMPFAANGKVDRKALLELPVSVQDSG
HCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHCCCEECCCC
PKCLPANADEALLLEIWGELLELPISDISTDESFFNLGGHSILLSRMLLRLREEFGRSIS
CEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCEE
INRFIELPTITKLATLVRGTDDSAVLSAQAMADAERPLEIEPLPISRMGDVHKVIVTGAN
ECCEEECCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEECCCCCHHCCCCEEEEEECCC
SFVGVHIVEALLGWGASEVACLVRDGGGQTAAQRFAQSLRENRLEHLDLSRVRIYSADIT
CHHHHHHHHHHHCCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
QPQLGLADGDFERLDREFGALVHNAANVNHVLDYESLAADNVEPIFELVRLCEGRSKKVF
CCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCHHHHCCCCHHHHHHHHHHHCCCCHHHH
NFVSTLSASSTVDDAGRVLELPAAPTPPIYIRNGYNLSKWVGERILERARERGVRVNLYR
HHHHHHCCCCCCCCCCCEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEC
PGNISFNSLSGVCQPHKNRLMLMLKGSIQLGQVPAFALNFDLMPVDFLARFIAFHASRYS
CCCCCHHHHCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCHHHHHHHHHHHHHCCC
PERAVFNLHNPEPLSWDAYVASFRETGSEFSLVSVADWQQQLGRVDADNALFGVLGFYLN
CCCCEEECCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHH
GFEEDIGDISLIGHANAQAGVQQMGAHYPEKSPALLRRGCDYLKEINFI
HHHHCCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA