Click here to switch to the map view.

The map label for this gene is ctaD [H]

Identifier: 77456306

GI number: 77456306

Start: 81389

End: 82981

Strand: Reverse

Name: ctaD [H]

Synonym: Pfl01_0078

Alternate gene names: 77456306

Gene position: 82981-81389 (Counterclockwise)

Preceding gene: 77456307

Following gene: 77456305

Centisome position: 1.29

GC content: 62.21

Gene sequence:

>1593_bases
ATGAGCGCTGTCATCGATGACCACGGTCATGCCGACCACGACCACGCCCACGGCCCCGCCAAAGGCCTGATGCGCTGGGT
GCTGACTACCAACCACAAGGACATCGGCACGCTGTACCTGTGGTTCGCGTTCTGCATGTTCCTGCTCGGCGGCTCGTTCG
CCATGGTGATCCGCGCCGAGCTGTTCCAGCCCGGATTGCAGATCGTCGAGCCTGCGTTCTTCAACCAGATGACCACCATG
CACGGCCTGGTGATGGTGTTCGGTGCGGTGATGCCGGCGTTCGTCGGCCTCGCCAACTGGATGATCCCGTTGATGGTCGG
TGCGCCGGACATGGCCCTGCCGCGGATGAACAACTTCAGCTTCTGGCTGCTGCCGGCGGCGTTCCTGCTGCTGGTCTCGA
CCCTGTTCACCGCCGGTGGCGGGCCGAACTTCGGCTGGACGTTCTACGCGCCGCTGTCCACCACCTATGCCCCGGAAAGC
GTGACGTTCTTCATCTTCGCCATCCACCTGATGGGGATCAGTTCGATCATGGGCGCGATCAACGTGATCGCCACCATCCT
CAACCTGCGCGCCCCCGGCATGACCCTGATGAAAATGCCGCTGTTCGTCTGGACGTGGCTGATCACCGCGTTCCTGCTGA
TCGCGGTGATGCCGGTGCTGGCCGGGTGCGTGACGATGATGCTGATGGACATCCACTTCGGCACCAGCTTCTTCAGTGCC
GCCGGTGGCGGTGACCCGGTGCTGTTCCAGCATGTGTTCTGGTTCTTCGGCCACCCCGAGGTGTACATCATGATCCTGCC
GGCCTTCGGTGCCGTCAGCCAGATCATCCCGACCTTCTCGCGCAAGCCGCTGTTCGGCTACACCTCGATGGTCTACGCCA
CGGCGAGCATCGCGTTCCTGTCGTTCATCGTCTGGGCGCACCACATGTTCGTGGTGGGCATCCCGCTGGTGGGCGAGTTG
TTCTTCATGTACGCGACGATGCTGATCGCGGTACCGACCGGGGTGAAGGTGTTCAACTGGGCCAGCACCATGTGGCAAGG
CTCGATGACCTTCGAGACGCCGATGCTGTTTGCCGTTGCGTTCGTGATCCTGTTCTCGATCGGCGGTTTCTCCGGGCTGA
TGCTGGCCATCGCGCCGGCGGACTTCCAGTACCAGGACACCTACTTCGTGGTCGCGCACTTCCACTACGTGCTGGTGCCG
GGGGCGATCTTCGGGATCTTCGCGTCGGCCTATTACTGGCTGCCGAAATGGACCGGCCACATGTACGACGAAACCCTGGG
CAAGCTGCACTTCTGGCTGTCCTTCGTCGGCATGAACCTGACCTTCTTCCCGATGCACTTCGTGGGTCTGGCGGGCATGC
CCCGGCGGATTCCGGACTACAACCTGCAGTTCGCCGACTTCAACATGGTGTCGTCGATCGGCGCGTTCATGTTCGGTGCC
ACGCAGATCTTCTTCCTGTTCATCGTGATCAAGACCATCCGTGGCGGCGAACCGGCTCCGGCCAAACCGTGGGATGGTGC
CGAAGGTCTGGAATGGAGCGTGCCGTCACCGGCGCCGTATCACACCTTCACCACGCCGCCGGAAGTGAAATGA

Upstream 100 bases:

>100_bases
CAGGCGGAAAGCAAATGAGCCGGTCTATTGCGTACTTCGTGAACCGGTCGGAGCCCTGCGCTCCGACCTGCCCAGTCCAC
TCACATGAAGGAGACCGGCC

Downstream 100 bases:

>100_bases
ACCCTGTAGCCGTTGAGGGCCGCCACCATGGCTGACTCGATTTCGATGAAGAAGCTGGTCACCCGACTGCTCGGCGTGGT
GGTGGCGATGTTCGTCTTCG

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MSAVIDDHGHADHDHAHGPAKGLMRWVLTTNHKDIGTLYLWFAFCMFLLGGSFAMVIRAELFQPGLQIVEPAFFNQMTTM
HGLVMVFGAVMPAFVGLANWMIPLMVGAPDMALPRMNNFSFWLLPAAFLLLVSTLFTAGGGPNFGWTFYAPLSTTYAPES
VTFFIFAIHLMGISSIMGAINVIATILNLRAPGMTLMKMPLFVWTWLITAFLLIAVMPVLAGCVTMMLMDIHFGTSFFSA
AGGGDPVLFQHVFWFFGHPEVYIMILPAFGAVSQIIPTFSRKPLFGYTSMVYATASIAFLSFIVWAHHMFVVGIPLVGEL
FFMYATMLIAVPTGVKVFNWASTMWQGSMTFETPMLFAVAFVILFSIGGFSGLMLAIAPADFQYQDTYFVVAHFHYVLVP
GAIFGIFASAYYWLPKWTGHMYDETLGKLHFWLSFVGMNLTFFPMHFVGLAGMPRRIPDYNLQFADFNMVSSIGAFMFGA
TQIFFLFIVIKTIRGGEPAPAKPWDGAEGLEWSVPSPAPYHTFTTPPEVK

Sequences:

>Translated_530_residues
MSAVIDDHGHADHDHAHGPAKGLMRWVLTTNHKDIGTLYLWFAFCMFLLGGSFAMVIRAELFQPGLQIVEPAFFNQMTTM
HGLVMVFGAVMPAFVGLANWMIPLMVGAPDMALPRMNNFSFWLLPAAFLLLVSTLFTAGGGPNFGWTFYAPLSTTYAPES
VTFFIFAIHLMGISSIMGAINVIATILNLRAPGMTLMKMPLFVWTWLITAFLLIAVMPVLAGCVTMMLMDIHFGTSFFSA
AGGGDPVLFQHVFWFFGHPEVYIMILPAFGAVSQIIPTFSRKPLFGYTSMVYATASIAFLSFIVWAHHMFVVGIPLVGEL
FFMYATMLIAVPTGVKVFNWASTMWQGSMTFETPMLFAVAFVILFSIGGFSGLMLAIAPADFQYQDTYFVVAHFHYVLVP
GAIFGIFASAYYWLPKWTGHMYDETLGKLHFWLSFVGMNLTFFPMHFVGLAGMPRRIPDYNLQFADFNMVSSIGAFMFGA
TQIFFLFIVIKTIRGGEPAPAKPWDGAEGLEWSVPSPAPYHTFTTPPEVK
>Mature_529_residues
SAVIDDHGHADHDHAHGPAKGLMRWVLTTNHKDIGTLYLWFAFCMFLLGGSFAMVIRAELFQPGLQIVEPAFFNQMTTMH
GLVMVFGAVMPAFVGLANWMIPLMVGAPDMALPRMNNFSFWLLPAAFLLLVSTLFTAGGGPNFGWTFYAPLSTTYAPESV
TFFIFAIHLMGISSIMGAINVIATILNLRAPGMTLMKMPLFVWTWLITAFLLIAVMPVLAGCVTMMLMDIHFGTSFFSAA
GGGDPVLFQHVFWFFGHPEVYIMILPAFGAVSQIIPTFSRKPLFGYTSMVYATASIAFLSFIVWAHHMFVVGIPLVGELF
FMYATMLIAVPTGVKVFNWASTMWQGSMTFETPMLFAVAFVILFSIGGFSGLMLAIAPADFQYQDTYFVVAHFHYVLVPG
AIFGIFASAYYWLPKWTGHMYDETLGKLHFWLSFVGMNLTFFPMHFVGLAGMPRRIPDYNLQFADFNMVSSIGAFMFGAT
QIFFLFIVIKTIRGGEPAPAKPWDGAEGLEWSVPSPAPYHTFTTPPEVK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=510, Percent_Identity=48.4313725490196, Blast_Score=447, Evalue=1e-125,
Organism=Escherichia coli, GI1786634, Length=514, Percent_Identity=39.4941634241245, Blast_Score=368, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6226519, Length=533, Percent_Identity=47.6547842401501, Blast_Score=469, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=50.3086419753086, Blast_Score=316, Evalue=5e-87,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=46.9879518072289, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 58850; Mature: 58719

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAVIDDHGHADHDHAHGPAKGLMRWVLTTNHKDIGTLYLWFAFCMFLLGGSFAMVIRAE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
LFQPGLQIVEPAFFNQMTTMHGLVMVFGAVMPAFVGLANWMIPLMVGAPDMALPRMNNFS
HHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
FWLLPAAFLLLVSTLFTAGGGPNFGWTFYAPLSTTYAPESVTFFIFAIHLMGISSIMGAI
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NVIATILNLRAPGMTLMKMPLFVWTWLITAFLLIAVMPVLAGCVTMMLMDIHFGTSFFSA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHC
AGGGDPVLFQHVFWFFGHPEVYIMILPAFGAVSQIIPTFSRKPLFGYTSMVYATASIAFL
CCCCCHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
SFIVWAHHMFVVGIPLVGELFFMYATMLIAVPTGVKVFNWASTMWQGSMTFETPMLFAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCHHHHHHHH
FVILFSIGGFSGLMLAIAPADFQYQDTYFVVAHFHYVLVPGAIFGIFASAYYWLPKWTGH
HHHHHHHCCHHCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
MYDETLGKLHFWLSFVGMNLTFFPMHFVGLAGMPRRIPDYNLQFADFNMVSSIGAFMFGA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHHH
TQIFFLFIVIKTIRGGEPAPAKPWDGAEGLEWSVPSPAPYHTFTTPPEVK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]