Click here to switch to the map view.

The map label for this gene is ctaC [H]

Identifier: 77456307

GI number: 77456307

Start: 83064

End: 84191

Strand: Reverse

Name: ctaC [H]

Synonym: Pfl01_0079

Alternate gene names: 77456307

Gene position: 84191-83064 (Counterclockwise)

Preceding gene: 77456309

Following gene: 77456306

Centisome position: 1.31

GC content: 60.46

Gene sequence:

>1128_bases
ATGATGCGACATCCACACGTCTGGATGGGCCTCCTGTTGTGGTCGATTTTCAGCCCGGTGCAAGCTGCCTGGACTGTGAA
TATGGCGCCTGGAGCGACTGAAATCAGTCACGCAGTATTCGACCTGCACATGACCATTTTCTGGATCTGTGTGGTGATCG
GGATCATCGTCTTCGGCGCCATGTTCTGGTCGATGATGGTGCACCGCCGTTCTACCGGGCAGGTCGCCGCAAAATTCCAC
GAAAGCACCACCGTCGAAATTCTCTGGACCGTCGTCCCGCTGCTGATTCTGGTGGCGATGGCCGTTCCGGCGACCGCGAC
CCTGATCAAGATGTACGACACCAGTGAGCCGGATATCGATATCCAGATCACCGGTTATCAGTGGAAGTGGCACTACAAAT
ACCTGGGCCAGGACGTCGAGTTCTTCAGCAACCTGGCCACGCCCGCCGAGCAGATCCACAACAAGGAAGCCAAGGGCGAG
CACTACCTGCTCGAGGTCGACAAGCCGCTGGTGCTGCCGACCGGCGCCAAGGTGCGCTTCCTCGTGACCTCCGCCGACGT
GATCCACTCCTGGTGGGTGCCGGCCTTCGCGGTCAAGCGCGATGCGATTCCCGGGTTCGTCAACGAAGCCTGGACCCGCA
TCGACAAGCCCGGCCTCTACCGTGGCCAGTGCGCCGAGCTGTGCGGCAAGGATCACGGCTTCATGCCGATCGTGGTCGAC
GTCAAGGAGAAGGCCGACTACGAAAAATGGCTCGCCGAGCGCAAGGCCGAAGCGTTGCAGCTCAAGGAGCTGACCAGCAA
GGAATGGACCCTCGACGAACTCAAGGAACGTGGCGACAAGATCTACCACACCACCTGCGTCGCCTGTCACCAGGCTGAAG
GCCAGGGCCTGCCGCCGATGTTCCCGGCCCTCAAAGGCTCGAAAATCGCCACCGGCCCGAAAGAGGCGCACCTGAGCATT
GTCTTCCACGGCAAGCCCGGCACCGCCATGGCGGCGTTCGGCAAGCAGCTGTCGGAAGTCGATATCGCAGCGGTCGTGAC
CTACGAACGTAACGCCTGGGGCAACAACAAGGGCGACATGGTCACGCCAAAAGAAGTGCTGGAGCTGAAACAGGCGGAAA
GCAAATGA

Upstream 100 bases:

>100_bases
GCAGCAAGGCCCGGCGATTCAAGTTCGTAGTCTGATGCAGCCGATCCCTTGCCGCAGGCGAAAGCCGGCGGGATAACAAG
AACGATAAGGGGAACCCGCA

Downstream 100 bases:

>100_bases
GCCGGTCTATTGCGTACTTCGTGAACCGGTCGGAGCCCTGCGCTCCGACCTGCCCAGTCCACTCACATGAAGGAGACCGG
CCATGAGCGCTGTCATCGAT

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MMRHPHVWMGLLLWSIFSPVQAAWTVNMAPGATEISHAVFDLHMTIFWICVVIGIIVFGAMFWSMMVHRRSTGQVAAKFH
ESTTVEILWTVVPLLILVAMAVPATATLIKMYDTSEPDIDIQITGYQWKWHYKYLGQDVEFFSNLATPAEQIHNKEAKGE
HYLLEVDKPLVLPTGAKVRFLVTSADVIHSWWVPAFAVKRDAIPGFVNEAWTRIDKPGLYRGQCAELCGKDHGFMPIVVD
VKEKADYEKWLAERKAEALQLKELTSKEWTLDELKERGDKIYHTTCVACHQAEGQGLPPMFPALKGSKIATGPKEAHLSI
VFHGKPGTAMAAFGKQLSEVDIAAVVTYERNAWGNNKGDMVTPKEVLELKQAESK

Sequences:

>Translated_375_residues
MMRHPHVWMGLLLWSIFSPVQAAWTVNMAPGATEISHAVFDLHMTIFWICVVIGIIVFGAMFWSMMVHRRSTGQVAAKFH
ESTTVEILWTVVPLLILVAMAVPATATLIKMYDTSEPDIDIQITGYQWKWHYKYLGQDVEFFSNLATPAEQIHNKEAKGE
HYLLEVDKPLVLPTGAKVRFLVTSADVIHSWWVPAFAVKRDAIPGFVNEAWTRIDKPGLYRGQCAELCGKDHGFMPIVVD
VKEKADYEKWLAERKAEALQLKELTSKEWTLDELKERGDKIYHTTCVACHQAEGQGLPPMFPALKGSKIATGPKEAHLSI
VFHGKPGTAMAAFGKQLSEVDIAAVVTYERNAWGNNKGDMVTPKEVLELKQAESK
>Mature_375_residues
MMRHPHVWMGLLLWSIFSPVQAAWTVNMAPGATEISHAVFDLHMTIFWICVVIGIIVFGAMFWSMMVHRRSTGQVAAKFH
ESTTVEILWTVVPLLILVAMAVPATATLIKMYDTSEPDIDIQITGYQWKWHYKYLGQDVEFFSNLATPAEQIHNKEAKGE
HYLLEVDKPLVLPTGAKVRFLVTSADVIHSWWVPAFAVKRDAIPGFVNEAWTRIDKPGLYRGQCAELCGKDHGFMPIVVD
VKEKADYEKWLAERKAEALQLKELTSKEWTLDELKERGDKIYHTTCVACHQAEGQGLPPMFPALKGSKIATGPKEAHLSI
VFHGKPGTAMAAFGKQLSEVDIAAVVTYERNAWGNNKGDMVTPKEVLELKQAESK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RPE1 insert domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=168, Percent_Identity=36.9047619047619, Blast_Score=131, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6226540, Length=247, Percent_Identity=31.1740890688259, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- InterPro:   IPR005728 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 42099; Mature: 42099

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRHPHVWMGLLLWSIFSPVQAAWTVNMAPGATEISHAVFDLHMTIFWICVVIGIIVFGA
CCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFWSMMVHRRSTGQVAAKFHESTTVEILWTVVPLLILVAMAVPATATLIKMYDTSEPDID
HHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
IQITGYQWKWHYKYLGQDVEFFSNLATPAEQIHNKEAKGEHYLLEVDKPLVLPTGAKVRF
EEEECEEEEEEHHHHCCHHHHHHHHCCCHHHHCCCCCCCCEEEEEECCCEEECCCCEEEE
LVTSADVIHSWWVPAFAVKRDAIPGFVNEAWTRIDKPGLYRGQCAELCGKDHGFMPIVVD
EEEEHHHHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEEEEE
VKEKADYEKWLAERKAEALQLKELTSKEWTLDELKERGDKIYHTTCVACHQAEGQGLPPM
CHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEHHHHEEECCCCCCCCCC
FPALKGSKIATGPKEAHLSIVFHGKPGTAMAAFGKQLSEVDIAAVVTYERNAWGNNKGDM
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCC
VTPKEVLELKQAESK
CCHHHHHHHHHHCCC
>Mature Secondary Structure
MMRHPHVWMGLLLWSIFSPVQAAWTVNMAPGATEISHAVFDLHMTIFWICVVIGIIVFGA
CCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFWSMMVHRRSTGQVAAKFHESTTVEILWTVVPLLILVAMAVPATATLIKMYDTSEPDID
HHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
IQITGYQWKWHYKYLGQDVEFFSNLATPAEQIHNKEAKGEHYLLEVDKPLVLPTGAKVRF
EEEECEEEEEEHHHHCCHHHHHHHHCCCHHHHCCCCCCCCEEEEEECCCEEECCCCEEEE
LVTSADVIHSWWVPAFAVKRDAIPGFVNEAWTRIDKPGLYRGQCAELCGKDHGFMPIVVD
EEEEHHHHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEEEEE
VKEKADYEKWLAERKAEALQLKELTSKEWTLDELKERGDKIYHTTCVACHQAEGQGLPPM
CHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEHHHHEEECCCCCCCCCC
FPALKGSKIATGPKEAHLSIVFHGKPGTAMAAFGKQLSEVDIAAVVTYERNAWGNNKGDM
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCC
VTPKEVLELKQAESK
CCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9823893; 11030655 [H]