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The map label for this gene is yfiK [H]

Identifier: 75908249

GI number: 75908249

Start: 2510792

End: 2511451

Strand: Direct

Name: yfiK [H]

Synonym: Ava_2028

Alternate gene names: 75908249

Gene position: 2510792-2511451 (Clockwise)

Preceding gene: 75908248

Following gene: 75908251

Centisome position: 39.44

GC content: 39.09

Gene sequence:

>660_bases
ATGATTAAAGTTTTATTAGTAGATGATCAAAATCTGATCCGTCAAGGATTAAGAGCATTATTAGAGCTAGAATCTGATAT
AGAAATTGTGGGAGAGGCAGAAAATGGAAAAATCGCTATTGATTTGATTCCCCAATTCCATCCAGATGTAGTATTGATGG
ATATGCGAATGCCAATTATGGATGGAGTAGCTGCTACACAAGAAATTCAACGAAATTTCCCCAGTGTTAAAGTTCTAGTC
CTCACAACTTTTGATGATGATGAATATGTCAAAGCGGCTTTACAAAATGGTGCAATGGGTTATTTACTCAAAGATACACC
CTCAGAAGAATTAGCTGTGGCAATTCGTGCAGTCGAGAAAGGTTACACTCAACTAGGCCCAGGAATAGTCAAGAAACTCT
TAGTGCAGTTTCAGTCTACACCAAACCACACGCCACCTGCGCCGACTAATTTAGCTGATCTTACGCCCAGAGAAAAAGAA
GTTTTACGCTTAATTGCCGCAGGTGCAAATAACAAAGAAATTGCCCAGCAACTCTATATTTCCGAGGGGACAGTTAAAAA
TCATGTGACGAATATTTTAAATCGTTTGAGTTTGCGCGATCGCACTCAAGCCGCTATCATTGCCAATACCTATTTAAGTC
ATCTCAATGAACCTGAATAA

Upstream 100 bases:

>100_bases
TGCGCGATCGCACTTTGGCTTTAGGAGGAAAATTTGCCATCAATAGCGATGTTGGTTATGGTTGTCAAATTACAGTTGAT
ATTCCTGCAAGCAGATTAAT

Downstream 100 bases:

>100_bases
AAGTGATTATCTGATTTCACGCAAACAAATTCAAACATTCCTGCCGAAGAATACCCTTAGTCACTTTGATGTTCCTAAAA
GATTTGGCAATTACTTCTTC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MIKVLLVDDQNLIRQGLRALLELESDIEIVGEAENGKIAIDLIPQFHPDVVLMDMRMPIMDGVAATQEIQRNFPSVKVLV
LTTFDDDEYVKAALQNGAMGYLLKDTPSEELAVAIRAVEKGYTQLGPGIVKKLLVQFQSTPNHTPPAPTNLADLTPREKE
VLRLIAAGANNKEIAQQLYISEGTVKNHVTNILNRLSLRDRTQAAIIANTYLSHLNEPE

Sequences:

>Translated_219_residues
MIKVLLVDDQNLIRQGLRALLELESDIEIVGEAENGKIAIDLIPQFHPDVVLMDMRMPIMDGVAATQEIQRNFPSVKVLV
LTTFDDDEYVKAALQNGAMGYLLKDTPSEELAVAIRAVEKGYTQLGPGIVKKLLVQFQSTPNHTPPAPTNLADLTPREKE
VLRLIAAGANNKEIAQQLYISEGTVKNHVTNILNRLSLRDRTQAAIIANTYLSHLNEPE
>Mature_219_residues
MIKVLLVDDQNLIRQGLRALLELESDIEIVGEAENGKIAIDLIPQFHPDVVLMDMRMPIMDGVAATQEIQRNFPSVKVLV
LTTFDDDEYVKAALQNGAMGYLLKDTPSEELAVAIRAVEKGYTQLGPGIVKKLLVQFQSTPNHTPPAPTNLADLTPREKE
VLRLIAAGANNKEIAQQLYISEGTVKNHVTNILNRLSLRDRTQAAIIANTYLSHLNEPE

Specific function: Member of the two-component regulatory system yfiJ/yfiK [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=38.3495145631068, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788222, Length=199, Percent_Identity=35.1758793969849, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787473, Length=203, Percent_Identity=35.9605911330049, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1786747, Length=196, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1790102, Length=205, Percent_Identity=30.7317073170732, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789937, Length=213, Percent_Identity=27.2300469483568, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788712, Length=195, Percent_Identity=25.1282051282051, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788546, Length=202, Percent_Identity=28.7128712871287, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI87082052, Length=106, Percent_Identity=40.5660377358491, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=36.697247706422, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787277, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788192, Length=104, Percent_Identity=37.5, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24229; Mature: 24229

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVLLVDDQNLIRQGLRALLELESDIEIVGEAENGKIAIDLIPQFHPDVVLMDMRMPIM
CEEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCEEEEECCCCHH
DGVAATQEIQRNFPSVKVLVLTTFDDDEYVKAALQNGAMGYLLKDTPSEELAVAIRAVEK
HHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHH
GYTQLGPGIVKKLLVQFQSTPNHTPPAPTNLADLTPREKEVLRLIAAGANNKEIAQQLYI
CHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
SEGTVKNHVTNILNRLSLRDRTQAAIIANTYLSHLNEPE
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIKVLLVDDQNLIRQGLRALLELESDIEIVGEAENGKIAIDLIPQFHPDVVLMDMRMPIM
CEEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCEEEEECCCCHH
DGVAATQEIQRNFPSVKVLVLTTFDDDEYVKAALQNGAMGYLLKDTPSEELAVAIRAVEK
HHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHH
GYTQLGPGIVKKLLVQFQSTPNHTPPAPTNLADLTPREKEVLRLIAAGANNKEIAQQLYI
CHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
SEGTVKNHVTNILNRLSLRDRTQAAIIANTYLSHLNEPE
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8973323; 9384377 [H]