BacMap

Definition	Anabaena variabilis ATCC 29413 chromosome, complete genome.
Accession	NC_007413
Length	6,365,727

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The map label for this gene is mvp [H]

Identifier: 75908251

GI number: 75908251

Start: 2511959

End: 2512750

Strand: Direct

Name: mvp [H]

Synonym: Ava_2030

Alternate gene names: 75908251

Gene position: 2511959-2512750 (Clockwise)

Preceding gene: 75908249

Following gene: 75908252

Centisome position: 39.46

GC content: 32.7

Gene sequence:

>792_bases
ATGTTACTGAGTAGACAACAAACTGAATTTTACTTAACAGACCTAGAAACACCATTAGGTAAAGCTATTAATTTGACAAT
TGCTGCCTTGGTTCTATTATCATCAGGCATCTTTGTCGCTCAAACCTACGCTATACCTGATTCTATTAGGTTGCAGTTGG
ATCAAATAGATACAGTTATATTGATAATTTTTGCAGTAGAGTATGTCCTCCGCCTTTGGAGTGCAGAAAATAAACTAAAG
TATATATTTAGCTTTTATGCCATTATTGATTTAATAGCAATTATGCCATTTTTATTAGGCTTAGTAAATATTAGCTTTAT
TCGGATATTACGCTGGTTTAGAATTTTAAGATTAATTAGATTCATTGATAGTAAATTTTTATTTGGCAGTATTAGTTCCG
AAGACGGGATAATTTTTATTCGCATACTGTTTACTTTGTTTACCATAATTTTTGTTTATTCTGGCTTAATTTATCAAGTA
GAACATCCCGTAAATGCTCAAGTTTATAATACTTTTTTAGATGCCTTTTATTTCTCAGTGGTCACAATGACTACTGTAGG
CTTTGGAGATTTAACTCCCATTTCAGAACTAGGTAGATTATTAACTGTATTGATGATTTTGACAGGTGTAGCCATCATTC
CTTGGCAAGTAGGAGATTTAATTAGGCGCGTAGTCAAAACAGCCAATCAGGTAGAAACTGTATGTTTGAATTGTGGTCTA
AAATTTCACGATCAGGATGCAGAGTTTTGTAAACGTTGCGGAACTAAATTACCCAGCCAAAAAATGGATTAA

Upstream 100 bases:

>100_bases
GCGATCGCTAGACGCATAAAATATTCTGGATTCATAATTATCTTGATATTTCAGTCAGATAGACGGTAAAAATACCATAT
TTAAGCAGATATCGTGAAGT

Downstream 100 bases:

>100_bases
CTCTAACCTATTAATCAAAAACCTCACCCATAAGACAGAAGTCATTGTAAATACACCAATCACACTAGTAATTAAGAGAG
ATTCGTGGTGCAAAACAATG

Product: Ion transport protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: MVP [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLLSRQQTEFYLTDLETPLGKAINLTIAALVLLSSGIFVAQTYAIPDSIRLQLDQIDTVILIIFAVEYVLRLWSAENKLK
YIFSFYAIIDLIAIMPFLLGLVNISFIRILRWFRILRLIRFIDSKFLFGSISSEDGIIFIRILFTLFTIIFVYSGLIYQV
EHPVNAQVYNTFLDAFYFSVVTMTTVGFGDLTPISELGRLLTVLMILTGVAIIPWQVGDLIRRVVKTANQVETVCLNCGL
KFHDQDAEFCKRCGTKLPSQKMD

Sequences:

>Translated_263_residues
MLLSRQQTEFYLTDLETPLGKAINLTIAALVLLSSGIFVAQTYAIPDSIRLQLDQIDTVILIIFAVEYVLRLWSAENKLK
YIFSFYAIIDLIAIMPFLLGLVNISFIRILRWFRILRLIRFIDSKFLFGSISSEDGIIFIRILFTLFTIIFVYSGLIYQV
EHPVNAQVYNTFLDAFYFSVVTMTTVGFGDLTPISELGRLLTVLMILTGVAIIPWQVGDLIRRVVKTANQVETVCLNCGL
KFHDQDAEFCKRCGTKLPSQKMD
>Mature_263_residues
MLLSRQQTEFYLTDLETPLGKAINLTIAALVLLSSGIFVAQTYAIPDSIRLQLDQIDTVILIIFAVEYVLRLWSAENKLK
YIFSFYAIIDLIAIMPFLLGLVNISFIRILRWFRILRLIRFIDSKFLFGSISSEDGIIFIRILFTLFTIIFVYSGLIYQV
EHPVNAQVYNTFLDAFYFSVVTMTTVGFGDLTPISELGRLLTVLMILTGVAIIPWQVGDLIRRVVKTANQVETVCLNCGL
KFHDQDAEFCKRCGTKLPSQKMD

Specific function: Voltage-gated potassium-selective channel opened by hyperpolarization [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the potassium channel family [H]

Homologues:

Organism=Homo sapiens, GI27436986, Length=171, Percent_Identity=32.1637426900585, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI27436984, Length=171, Percent_Identity=32.1637426900585, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI9789987, Length=171, Percent_Identity=32.1637426900585, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI27436981, Length=171, Percent_Identity=30.9941520467836, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI20070166, Length=198, Percent_Identity=30.3030303030303, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI27436974, Length=182, Percent_Identity=29.6703296703297, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI236462079, Length=174, Percent_Identity=28.1609195402299, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI236461719, Length=174, Percent_Identity=28.1609195402299, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI236462242, Length=174, Percent_Identity=28.1609195402299, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI236461942, Length=174, Percent_Identity=28.1609195402299, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI28373065, Length=174, Percent_Identity=28.1609195402299, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI26051262, Length=240, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI26051260, Length=240, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI26051266, Length=240, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI26051264, Length=240, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4826784, Length=182, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4504817, Length=179, Percent_Identity=27.3743016759777, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI88758565, Length=175, Percent_Identity=26.2857142857143, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI19424136, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4826782, Length=178, Percent_Identity=25.8426966292135, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI25952087, Length=182, Percent_Identity=26.3736263736264, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI26638655, Length=174, Percent_Identity=25.2873563218391, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI26638653, Length=174, Percent_Identity=25.2873563218391, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI119395748, Length=177, Percent_Identity=25.9887005649718, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI26051268, Length=177, Percent_Identity=28.2485875706215, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4504821, Length=223, Percent_Identity=23.7668161434978, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI24497458, Length=185, Percent_Identity=29.1891891891892, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4758630, Length=194, Percent_Identity=28.8659793814433, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21217561, Length=182, Percent_Identity=29.1208791208791, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21217563, Length=185, Percent_Identity=29.1891891891892, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI238624130, Length=209, Percent_Identity=27.7511961722488, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI62388890, Length=209, Percent_Identity=27.7511961722488, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI26638650, Length=209, Percent_Identity=27.7511961722488, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI238624132, Length=209, Percent_Identity=27.7511961722488, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI27436988, Length=186, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI163792201, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI4826786, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17544122, Length=171, Percent_Identity=33.9181286549708, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71989376, Length=219, Percent_Identity=26.9406392694064, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71989381, Length=219, Percent_Identity=26.9406392694064, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71989369, Length=219, Percent_Identity=26.9406392694064, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71989361, Length=219, Percent_Identity=26.9406392694064, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25147238, Length=222, Percent_Identity=29.2792792792793, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25147242, Length=222, Percent_Identity=29.2792792792793, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994313, Length=196, Percent_Identity=26.530612244898, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193206869, Length=179, Percent_Identity=29.608938547486, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25148255, Length=179, Percent_Identity=29.608938547486, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994320, Length=176, Percent_Identity=27.8409090909091, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994134, Length=189, Percent_Identity=24.8677248677249, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71986011, Length=197, Percent_Identity=25.3807106598985, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71986008, Length=197, Percent_Identity=25.3807106598985, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71986003, Length=197, Percent_Identity=25.3807106598985, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161084970, Length=171, Percent_Identity=32.7485380116959, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17737641, Length=171, Percent_Identity=32.7485380116959, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI116007764, Length=183, Percent_Identity=27.8688524590164, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24656289, Length=183, Percent_Identity=27.8688524590164, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24656294, Length=183, Percent_Identity=27.8688524590164, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45555859, Length=189, Percent_Identity=26.984126984127, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI45549143, Length=189, Percent_Identity=26.984126984127, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24642910, Length=189, Percent_Identity=26.984126984127, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24642914, Length=189, Percent_Identity=26.984126984127, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24642916, Length=189, Percent_Identity=26.984126984127, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281365536, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221330117, Length=178, Percent_Identity=29.2134831460674, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221330119, Length=178, Percent_Identity=29.2134831460674, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281363095, Length=178, Percent_Identity=29.2134831460674, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281363097, Length=178, Percent_Identity=29.2134831460674, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003091 [H]

Pfam domain/function: PF07885 Ion_trans_2 [H]

EC number: NA

Molecular weight: Translated: 29976; Mature: 29976

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSRQQTEFYLTDLETPLGKAINLTIAALVLLSSGIFVAQTYAIPDSIRLQLDQIDTVI
CCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
LIIFAVEYVLRLWSAENKLKYIFSFYAIIDLIAIMPFLLGLVNISFIRILRWFRILRLIR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIDSKFLFGSISSEDGIIFIRILFTLFTIIFVYSGLIYQVEHPVNAQVYNTFLDAFYFSV
HHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHH
VTMTTVGFGDLTPISELGRLLTVLMILTGVAIIPWQVGDLIRRVVKTANQVETVCLNCGL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KFHDQDAEFCKRCGTKLPSQKMD
CCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLLSRQQTEFYLTDLETPLGKAINLTIAALVLLSSGIFVAQTYAIPDSIRLQLDQIDTVI
CCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
LIIFAVEYVLRLWSAENKLKYIFSFYAIIDLIAIMPFLLGLVNISFIRILRWFRILRLIR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIDSKFLFGSISSEDGIIFIRILFTLFTIIFVYSGLIYQVEHPVNAQVYNTFLDAFYFSV
HHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHH
VTMTTVGFGDLTPISELGRLLTVLMILTGVAIIPWQVGDLIRRVVKTANQVETVCLNCGL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KFHDQDAEFCKRCGTKLPSQKMD
CCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12640457; 8688087 [H]