Click here to switch to the map view.

The map label for this gene is hfq [H]

Identifier: 75675641

GI number: 75675641

Start: 1579848

End: 1580096

Strand: Direct

Name: hfq [H]

Synonym: Nwi_1449

Alternate gene names: 75675641

Gene position: 1579848-1580096 (Clockwise)

Preceding gene: 75675640

Following gene: 75675642

Centisome position: 46.44

GC content: 53.82

Gene sequence:

>249_bases
ATGGCGATAGACCGCGCACAAAACCTACAGGACACTTTCCTCAACCACGTCCGTAAGACGAAAACGCCTCTGACGATCTT
TCTGGTAAACGGAGTCAAGCTCCAGGGAATCGTGACCTGGTTCGACAATTTCTGCCTGCTGCTCAGGCGCGACGGTCATT
CACAACTGGTCTACAAACACGCGATTTCGACCATCATGCCGGGTGCTCCGATCCAGTTGTTTGAAGGCGGCGAGGATGCT
CCGCTTTGA

Upstream 100 bases:

>100_bases
TCCATGAGGAGGATCTCAGAGGGGAGCCGGCGGGCCATGAAACGCTCGGGAGGGCTGCTTCCGGCTCCAAAAAGCAAAGT
TAAACTGCGGGATAACAAAA

Downstream 100 bases:

>100_bases
GCACATACTTGAAAGTTTCCTGATTGGACCCCCGCCAGTTCGAGGGGAGCACCGACCCGTCGGGGTCGATGCGGGGCGAG
CCAACCGGACGAGCGATCGT

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 81

Protein sequence:

>82_residues
MAIDRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKHAISTIMPGAPIQLFEGGEDA
PL

Sequences:

>Translated_82_residues
MAIDRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKHAISTIMPGAPIQLFEGGEDA
PL
>Mature_81_residues
AIDRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKHAISTIMPGAPIQLFEGGEDAP
L

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=52.2388059701493, Blast_Score=80, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 9235; Mature: 9104

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKH
CCCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHEEEEECCCCCHHHHHH
AISTIMPGAPIQLFEGGEDAPL
HHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
AIDRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKH
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHEEEEECCCCCHHHHHH
AISTIMPGAPIQLFEGGEDAPL
HHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]