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The map label for this gene is hflX [H]

Identifier: 75675642

GI number: 75675642

Start: 1580165

End: 1581493

Strand: Direct

Name: hflX [H]

Synonym: Nwi_1450

Alternate gene names: 75675642

Gene position: 1580165-1581493 (Clockwise)

Preceding gene: 75675641

Following gene: 75675643

Centisome position: 46.45

GC content: 63.81

Gene sequence:

>1329_bases
ATGCGGGGCGAGCCAACCGGACGAGCGATCGTCATCGGCCCTTACGTGCGGACGCGGGGCGGCGATGCCGAGACGCCGCG
ACGATCCCTGCGCAACACCGACGCCCGGCTGGATGAAGCCGCCGGTCTCGCCAAGGCAATCGACCTCCATGTGATTCAGG
CGATCGTCGCTCCCGTCAGCCAGATCAGGCCCGCGACATATCTCGGTAAGGGCAAGGTCGAGGAGTTGCAGGGCTTGATC
GCCGCCGATGGAGCCGGTCTCGTGGTGATGGACTGCGCGCTGTCGCCCATTCAACAGCGCAATCTGGAAAAGGCCTGGAG
CACAAAGGTGCTGGACCGCACCGGCTTGATCCTCGAAATCTTCGGGCGCCGCGCCAAGACCAAAGAGGGCGCGCTTCAGG
TCGAACTCGCTCATCTCAACTATCAGCGCAGCCGTCTGGTGCGCTCCTGGACCCACCTCGAACGGCAGCGTGGCGGCTTC
GGATTCATGGGCGGGCCCGGCGAAACCCAGATCGAGGCGGATCGCCGCCTGATCGGCGATCGCATCACGCGACTGGAAAA
CGAACTCAAGAAGGTGCAGGCGACGCGGCGGCTGCATCGCGCCGGGCGGCAGCGCGTGCCCTATCGCGTGGTCGCGCTGG
TCGGCTACACGAATGCCGGCAAATCGACGCTGTTCAATCGATTGACGCGCGCGGACGTTCAGGCCGCCGACATGCTGTTC
GCGACGCTCGATCCGACGCTGCGCTCGCTCGCGCTGCCTCACGGCGGAAAGGCCATGCTGTCGGACACCGTCGGATTCAT
ATCTAATCTGCCGACCCAGCTCGTCGCTGCTTTCCGCGCGACGTTGGAGGAGGTGATGGAGGCGGACGTTATCCTTCATG
TTCGTGACATTTCGCATGAGGATACGGAGCCGCAGCAGCACGATGTCGAAGCCGTGCTGCATCAACTCGGCATCGACCCC
GACGGACCGGCGCGCATGATCGAGGTCTGGAACAAGATCGATCGCTTCGATGCGGATCAGCGCAAAGACCTGGAGAACGT
GGCTGCACGCCGTTCGACGGATGTGCCGCGTTTTCTTGTTTCTGCCGAAACCGGCGAAGGGGTTGAGACGCTGCTTGCGG
CGATCGAGGATCGGCTGGCGGCAACCCGAACCACGCTGGATCTGTCGGTCGACGCCTCGGATGGCGCGGCGATCAGCTGG
CTGCATCGGAACTCCGAGGTGCTCGCCAAGGAACTACGCGACGGCCGCTACGACATGACCGTCAGGGTCGATGAGACAAA
ACGTGACATACTCGTCAATCGGTATGGCGCGGCGCCACGTCCGCTTTGA

Upstream 100 bases:

>100_bases
TGTTTGAAGGCGGCGAGGATGCTCCGCTTTGAGCACATACTTGAAAGTTTCCTGATTGGACCCCCGCCAGTTCGAGGGGA
GCACCGACCCGTCGGGGTCG

Downstream 100 bases:

>100_bases
TTTCCGCTCGCAAAGCAAGGCCGCGCAAGGATGGTCTTGACCGGCGGAACGCCGGACTATTCCATGTCCATCAAATCACA
TGAAAGCCGCAGGAGATTTC

Product: GTP-binding protein, HSR1-related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MRGEPTGRAIVIGPYVRTRGGDAETPRRSLRNTDARLDEAAGLAKAIDLHVIQAIVAPVSQIRPATYLGKGKVEELQGLI
AADGAGLVVMDCALSPIQQRNLEKAWSTKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQRSRLVRSWTHLERQRGGF
GFMGGPGETQIEADRRLIGDRITRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKSTLFNRLTRADVQAADMLF
ATLDPTLRSLALPHGGKAMLSDTVGFISNLPTQLVAAFRATLEEVMEADVILHVRDISHEDTEPQQHDVEAVLHQLGIDP
DGPARMIEVWNKIDRFDADQRKDLENVAARRSTDVPRFLVSAETGEGVETLLAAIEDRLAATRTTLDLSVDASDGAAISW
LHRNSEVLAKELRDGRYDMTVRVDETKRDILVNRYGAAPRPL

Sequences:

>Translated_442_residues
MRGEPTGRAIVIGPYVRTRGGDAETPRRSLRNTDARLDEAAGLAKAIDLHVIQAIVAPVSQIRPATYLGKGKVEELQGLI
AADGAGLVVMDCALSPIQQRNLEKAWSTKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQRSRLVRSWTHLERQRGGF
GFMGGPGETQIEADRRLIGDRITRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKSTLFNRLTRADVQAADMLF
ATLDPTLRSLALPHGGKAMLSDTVGFISNLPTQLVAAFRATLEEVMEADVILHVRDISHEDTEPQQHDVEAVLHQLGIDP
DGPARMIEVWNKIDRFDADQRKDLENVAARRSTDVPRFLVSAETGEGVETLLAAIEDRLAATRTTLDLSVDASDGAAISW
LHRNSEVLAKELRDGRYDMTVRVDETKRDILVNRYGAAPRPL
>Mature_442_residues
MRGEPTGRAIVIGPYVRTRGGDAETPRRSLRNTDARLDEAAGLAKAIDLHVIQAIVAPVSQIRPATYLGKGKVEELQGLI
AADGAGLVVMDCALSPIQQRNLEKAWSTKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQRSRLVRSWTHLERQRGGF
GFMGGPGETQIEADRRLIGDRITRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKSTLFNRLTRADVQAADMLF
ATLDPTLRSLALPHGGKAMLSDTVGFISNLPTQLVAAFRATLEEVMEADVILHVRDISHEDTEPQQHDVEAVLHQLGIDP
DGPARMIEVWNKIDRFDADQRKDLENVAARRSTDVPRFLVSAETGEGVETLLAAIEDRLAATRTTLDLSVDASDGAAISW
LHRNSEVLAKELRDGRYDMTVRVDETKRDILVNRYGAAPRPL

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=341, Percent_Identity=33.4310850439883, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI310133116, Length=265, Percent_Identity=35.8490566037736, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI310124269, Length=267, Percent_Identity=34.8314606741573, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI310124267, Length=267, Percent_Identity=34.8314606741573, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI310124171, Length=267, Percent_Identity=34.8314606741573, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI310124169, Length=267, Percent_Identity=34.8314606741573, Blast_Score=132, Evalue=7e-31,
Organism=Escherichia coli, GI1790615, Length=390, Percent_Identity=42.8205128205128, Blast_Score=272, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17561038, Length=417, Percent_Identity=32.8537170263789, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24650079, Length=420, Percent_Identity=32.8571428571429, Blast_Score=161, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48925; Mature: 48925

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGEPTGRAIVIGPYVRTRGGDAETPRRSLRNTDARLDEAAGLAKAIDLHVIQAIVAPVS
CCCCCCCCEEEEECCEECCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIRPATYLGKGKVEELQGLIAADGAGLVVMDCALSPIQQRNLEKAWSTKVLDRTGLILEI
HCCCCHHCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHH
FGRRAKTKEGALQVELAHLNYQRSRLVRSWTHLERQRGGFGFMGGPGETQIEADRRLIGD
HCCCCCCCCCCEEEEEHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
RITRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKSTLFNRLTRADVQAADMLF
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ATLDPTLRSLALPHGGKAMLSDTVGFISNLPTQLVAAFRATLEEVMEADVILHVRDISHE
HHHCHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
DTEPQQHDVEAVLHQLGIDPDGPARMIEVWNKIDRFDADQRKDLENVAARRSTDVPRFLV
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEE
SAETGEGVETLLAAIEDRLAATRTTLDLSVDASDGAAISWLHRNSEVLAKELRDGRYDMT
ECCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEEEECCCHHHHHHHHCCCCEEEE
VRVDETKRDILVNRYGAAPRPL
EEECCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRGEPTGRAIVIGPYVRTRGGDAETPRRSLRNTDARLDEAAGLAKAIDLHVIQAIVAPVS
CCCCCCCCEEEEECCEECCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIRPATYLGKGKVEELQGLIAADGAGLVVMDCALSPIQQRNLEKAWSTKVLDRTGLILEI
HCCCCHHCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHH
FGRRAKTKEGALQVELAHLNYQRSRLVRSWTHLERQRGGFGFMGGPGETQIEADRRLIGD
HCCCCCCCCCCEEEEEHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
RITRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKSTLFNRLTRADVQAADMLF
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ATLDPTLRSLALPHGGKAMLSDTVGFISNLPTQLVAAFRATLEEVMEADVILHVRDISHE
HHHCHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
DTEPQQHDVEAVLHQLGIDPDGPARMIEVWNKIDRFDADQRKDLENVAARRSTDVPRFLV
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEE
SAETGEGVETLLAAIEDRLAATRTTLDLSVDASDGAAISWLHRNSEVLAKELRDGRYDMT
ECCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEEEECCCHHHHHHHHCCCCEEEE
VRVDETKRDILVNRYGAAPRPL
EEECCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]