Click here to switch to the map view.

The map label for this gene is exbB [H]

Identifier: 75674900

GI number: 75674900

Start: 785786

End: 786988

Strand: Direct

Name: exbB [H]

Synonym: Nwi_0703

Alternate gene names: 75674900

Gene position: 785786-786988 (Clockwise)

Preceding gene: 75674899

Following gene: 75674901

Centisome position: 23.1

GC content: 68.83

Gene sequence:

>1203_bases
ATGATAGCGCTGGCAAGCCAACAGATATCCGGAACAAAGAGCATGATTGTGAGACTTGCGAAGGCGACGATCCATCTGAC
GTTTGCAGCGTTATTGGCTGTCCTCGTTCCATCGGCTACGGTTTTTGCCCAGCACCGGGCGTCGTCCCCGTCGACGACAT
CGTCCGGGGGGGGGGCGGCGGCAACTCCTTCTGCTTCTTCGGTGAACGGCTCTGCGGGGGCGGCTTCGGCTGCGTCTGCA
TCGCCGGGGCCGGCGAGTTCTGCTCCGTCGGCCACTGACGGGTCGGCTGGGGCTGCGTCATCGCAGCCGTCGGCGTCGAC
GTCTCCCGAGGGGGCGTCTGATGCGTCGTCCGGGGAGGGGTCTGCTTCATCTGATGCGTCTGCGGGTGCATCGTCGGACG
CGGCCGCGCCGTCGGATCAATCCGCCGCGCCGGATTCCGCCGCGCCGTCGCCTGCGCCGGAGGGCTCGTCGTCGACGCTT
CCGCAGGACCTGTCGCCGTGGGGCATGTTCATGCAGGCGGACATCGTCGTGAAAGCGGTAATGATCGGTTTGGCGTTCGC
ATCATTGGTAACGTGGACGGTCTGGCTGGCCAAGGGGATCGAGCTCGCGGCGTCGCGGCGGCGGGCGCAGAGCTGCGTGC
GCAAGCTGGAGCGCGCCGACAGCCTCGATGCCGCGCGCTCCGAGATCGCCGAGGGCTGGACCTGTGAGGGCACAGTGGCG
GATCTGATGGGGGCGGCGGAGCGCGAGCTGCAGCGCTCGGGCGATCTGTCGTCCGAGGGCATCAAGGAGCGGCTGGCGAT
CGCGCTGTCGCGCATCGAGGCCAAGGCGGGGCGCGACATCGCCCGCGGCACCGGCCTGCTGGCGACCATCGGGGCGACCG
CGCCGTTCGTCGGCCTGTTCGGCACGGTGTGGGGCATCATGAACGCCTTCATCGGCATCTCGCAGACCAAGACCACCAAC
CTCGCGGTGGTGGCGCCGGGCATTGCCGAGGCGCTGCTTGCGACCGCGCTCGGGCTTGTCGCCGCGATCCCGGCGGTGAT
CATCTACAACGTGTTCGCTCGCGCGCTTTCGAGCTACCGGGCGCTGCTGTCGGACGCCTCCGGCGAGATCATTCAGCACA
TCTCGCGCGATCTGGAGCGGCAGGAGCGGGGGCTCGGCCCGTCCGTGGTGGCGCTGTCGCGCGGCCGCGCTGCGGCTGAG
TGA

Upstream 100 bases:

>100_bases
GCCTTCATCCTTGAGCGGCTATTGAAAAGCTCCCGGCTGCGCTGCCAAGAAATGCCGTGTGGTTTCTGCTCGACCTTTGG
GCAGCTGTTTAAGGGGCGAA

Downstream 100 bases:

>100_bases
TGCGCCATGGGGGTATCGCTGAAGAACCCGCAGGATGGCGGCATCGACGAGCTGAGCGAGATCAACGTCACGCCGTTCAT
CGACGTGATGCTGGTGCTTT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MIALASQQISGTKSMIVRLAKATIHLTFAALLAVLVPSATVFAQHRASSPSTTSSGGGAAATPSASSVNGSAGAASAASA
SPGPASSAPSATDGSAGAASSQPSASTSPEGASDASSGEGSASSDASAGASSDAAAPSDQSAAPDSAAPSPAPEGSSSTL
PQDLSPWGMFMQADIVVKAVMIGLAFASLVTWTVWLAKGIELAASRRRAQSCVRKLERADSLDAARSEIAEGWTCEGTVA
DLMGAAERELQRSGDLSSEGIKERLAIALSRIEAKAGRDIARGTGLLATIGATAPFVGLFGTVWGIMNAFIGISQTKTTN
LAVVAPGIAEALLATALGLVAAIPAVIIYNVFARALSSYRALLSDASGEIIQHISRDLERQERGLGPSVVALSRGRAAAE

Sequences:

>Translated_400_residues
MIALASQQISGTKSMIVRLAKATIHLTFAALLAVLVPSATVFAQHRASSPSTTSSGGGAAATPSASSVNGSAGAASAASA
SPGPASSAPSATDGSAGAASSQPSASTSPEGASDASSGEGSASSDASAGASSDAAAPSDQSAAPDSAAPSPAPEGSSSTL
PQDLSPWGMFMQADIVVKAVMIGLAFASLVTWTVWLAKGIELAASRRRAQSCVRKLERADSLDAARSEIAEGWTCEGTVA
DLMGAAERELQRSGDLSSEGIKERLAIALSRIEAKAGRDIARGTGLLATIGATAPFVGLFGTVWGIMNAFIGISQTKTTN
LAVVAPGIAEALLATALGLVAAIPAVIIYNVFARALSSYRALLSDASGEIIQHISRDLERQERGLGPSVVALSRGRAAAE
>Mature_400_residues
MIALASQQISGTKSMIVRLAKATIHLTFAALLAVLVPSATVFAQHRASSPSTTSSGGGAAATPSASSVNGSAGAASAASA
SPGPASSAPSATDGSAGAASSQPSASTSPEGASDASSGEGSASSDASAGASSDAAAPSDQSAAPDSAAPSPAPEGSSSTL
PQDLSPWGMFMQADIVVKAVMIGLAFASLVTWTVWLAKGIELAASRRRAQSCVRKLERADSLDAARSEIAEGWTCEGTVA
DLMGAAERELQRSGDLSSEGIKERLAIALSRIEAKAGRDIARGTGLLATIGATAPFVGLFGTVWGIMNAFIGISQTKTTN
LAVVAPGIAEALLATALGLVAAIPAVIIYNVFARALSSYRALLSDASGEIIQHISRDLERQERGLGPSVVALSRGRAAAE

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=224, Percent_Identity=54.0178571428571, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1786958, Length=197, Percent_Identity=33.502538071066, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 39847; Mature: 39847

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALASQQISGTKSMIVRLAKATIHLTFAALLAVLVPSATVFAQHRASSPSTTSSGGGAA
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCC
ATPSASSVNGSAGAASAASASPGPASSAPSATDGSAGAASSQPSASTSPEGASDASSGEG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SASSDASAGASSDAAAPSDQSAAPDSAAPSPAPEGSSSTLPQDLSPWGMFMQADIVVKAV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
MIGLAFASLVTWTVWLAKGIELAASRRRAQSCVRKLERADSLDAARSEIAEGWTCEGTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHH
DLMGAAERELQRSGDLSSEGIKERLAIALSRIEAKAGRDIARGTGLLATIGATAPFVGLF
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHCCHHHHHHHH
GTVWGIMNAFIGISQTKTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNVFARALSSYR
HHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLSDASGEIIQHISRDLERQERGLGPSVVALSRGRAAAE
HHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MIALASQQISGTKSMIVRLAKATIHLTFAALLAVLVPSATVFAQHRASSPSTTSSGGGAA
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCC
ATPSASSVNGSAGAASAASASPGPASSAPSATDGSAGAASSQPSASTSPEGASDASSGEG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SASSDASAGASSDAAAPSDQSAAPDSAAPSPAPEGSSSTLPQDLSPWGMFMQADIVVKAV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
MIGLAFASLVTWTVWLAKGIELAASRRRAQSCVRKLERADSLDAARSEIAEGWTCEGTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHH
DLMGAAERELQRSGDLSSEGIKERLAIALSRIEAKAGRDIARGTGLLATIGATAPFVGLF
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHCCHHHHHHHH
GTVWGIMNAFIGISQTKTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNVFARALSSYR
HHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLSDASGEIIQHISRDLERQERGLGPSVVALSRGRAAAE
HHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]