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The map label for this gene is zur [H]

Identifier: 75674691

GI number: 75674691

Start: 550148

End: 550681

Strand: Direct

Name: zur [H]

Synonym: Nwi_0493

Alternate gene names: 75674691

Gene position: 550148-550681 (Clockwise)

Preceding gene: 75674690

Following gene: 75674692

Centisome position: 16.17

GC content: 63.48

Gene sequence:

>534_bases
ATGGGGAGCGGAACTGGTTCAAACGGGTTAATGGATAATCGAATGACCGCGACCAGACCGACATTCCCCGTTCCGGGACA
TGACCACGACCGCTGCGCCGCCGAGGCGATCAGCCACGCTGAGCAAATCTGCGCGCGGCGCGGCCAGAAGTTCACGCCGA
TCCGCCGTCAGGTGCTGCAGGCGCTGCTGTCGAGCCATCGGCCCCTCGGCGCCTATGAGGTGATCGAGGAACTGGCGAAA
TCGATCCCGCGCCCGGCGCCGATCACGGTCTATCGCGCGCTCGATTTTCTGATGGGGAACGGTCTGGTTCACCGGATCGA
AAGCCGCAATGCGTTTCTGGCCTGCGGGCACGACCATGATGAGAGCGCGATGGTGGCGTTTCTGATCTGCGAGCAGTGCG
GTTCGGTCGGCGAGATTCCAGCAAGCCGCGTGGCGCGGAGTCTGAGCGATGCCGTCCGCACCACGGGGTTCACCCCGAAA
CTCTCCGTGGTTGAAATTACCGGCACCTGCGCGCATTGCCAGAACGCGTCCTGA

Upstream 100 bases:

>100_bases
CCTGGCGGCGCTCCTGGATGTGGCGCGCGTGGGTTGTTATTTAGGGTATGTCATGTTGCATTGCGGCGCGAACTGAGAAA
GTTTTCGGGATGATCCTGAA

Downstream 100 bases:

>100_bases
ATCGAGAGCCGCCGGCCGTGAACTCCCGTTGACGATTTTGGTTGACCTCTTCGCTGCGATTTTTGTTATAAATCAATGTC
TTGCTTTGATTTAACGGTGA

Product: ferric-uptake regulator

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MGSGTGSNGLMDNRMTATRPTFPVPGHDHDRCAAEAISHAEQICARRGQKFTPIRRQVLQALLSSHRPLGAYEVIEELAK
SIPRPAPITVYRALDFLMGNGLVHRIESRNAFLACGHDHDESAMVAFLICEQCGSVGEIPASRVARSLSDAVRTTGFTPK
LSVVEITGTCAHCQNAS

Sequences:

>Translated_177_residues
MGSGTGSNGLMDNRMTATRPTFPVPGHDHDRCAAEAISHAEQICARRGQKFTPIRRQVLQALLSSHRPLGAYEVIEELAK
SIPRPAPITVYRALDFLMGNGLVHRIESRNAFLACGHDHDESAMVAFLICEQCGSVGEIPASRVARSLSDAVRTTGFTPK
LSVVEITGTCAHCQNAS
>Mature_176_residues
GSGTGSNGLMDNRMTATRPTFPVPGHDHDRCAAEAISHAEQICARRGQKFTPIRRQVLQALLSSHRPLGAYEVIEELAKS
IPRPAPITVYRALDFLMGNGLVHRIESRNAFLACGHDHDESAMVAFLICEQCGSVGEIPASRVARSLSDAVRTTGFTPKL
SVVEITGTCAHCQNAS

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=139, Percent_Identity=35.9712230215827, Blast_Score=97, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 19082; Mature: 18951

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSGTGSNGLMDNRMTATRPTFPVPGHDHDRCAAEAISHAEQICARRGQKFTPIRRQVLQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ALLSSHRPLGAYEVIEELAKSIPRPAPITVYRALDFLMGNGLVHRIESRNAFLACGHDHD
HHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHEEECCCCEEEEECCCCC
ESAMVAFLICEQCGSVGEIPASRVARSLSDAVRTTGFTPKLSVVEITGTCAHCQNAS
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
GSGTGSNGLMDNRMTATRPTFPVPGHDHDRCAAEAISHAEQICARRGQKFTPIRRQVLQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ALLSSHRPLGAYEVIEELAKSIPRPAPITVYRALDFLMGNGLVHRIESRNAFLACGHDHD
HHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHEEECCCCEEEEECCCCC
ESAMVAFLICEQCGSVGEIPASRVARSLSDAVRTTGFTPKLSVVEITGTCAHCQNAS
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]