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The map label for this gene is pyrR [H]

Identifier: 74318599

GI number: 74318599

Start: 2656439

End: 2656933

Strand: Direct

Name: pyrR [H]

Synonym: Tbd_2581

Alternate gene names: 74318599

Gene position: 2656439-2656933 (Clockwise)

Preceding gene: 74318598

Following gene: 74318600

Centisome position: 91.29

GC content: 67.27

Gene sequence:

>495_bases
ATGCACGCCTCACTGCCTGACGCCAACACGCTGATCGCGCGGCTCGCCGAAAGCATCGCCCCGACGTTCGCGCCCGAGAC
CGTGATCGTCGGCATCCACAGCGGCGGCGTCTGGGTCGCCGAGCGGCTCCACGCGCTGCTGAAGTGCGCGTCGCCCGTCG
GCGCGCTCGACATTTCGTTTTACCGCGACGACTTTTCGCGCATCGGCCTGCATCCGCAGGTGAAACCGTCGAACCTGCCG
TTCGACCTCGAGAACCGCGTCATCCTGCTCGTCGACGACGTCCTGCACACCGGGCGCACCGTACGTGCGGCGATGAACGA
GCTGTTCGATTACGGCCGCCCCGCGTCGATTCGGCTCGCCGTGCTCGTCGATCGCGGCGGACGCGAGCTGCCGATCCGCC
CGGATTTCGCCGCGCTCACACTCGAGGTCCCGCCTCACCAGAACATCAATCTCTCACGCCTCGACGACGGCCACCTCACG
CTCAGCCTCGCATGA

Upstream 100 bases:

>100_bases
ACCGCCGAATCGGAACTCCACGCCCGGGGCATCCACGGCAAGAAAAACAAGGCGCTGACCGACGCGGTCGCCGCACAACT
CATCCTGCAGGGTTTTTTTG

Downstream 100 bases:

>100_bases
ATCCACAACTGACGCCGGACGGCAGGCTGCGCCACCTGCTGACGCTCGACGGCCTGCCGCGCGCGACCCTGACGCACATC
CTCGACACCGCCGAATCCTT

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MHASLPDANTLIARLAESIAPTFAPETVIVGIHSGGVWVAERLHALLKCASPVGALDISFYRDDFSRIGLHPQVKPSNLP
FDLENRVILLVDDVLHTGRTVRAAMNELFDYGRPASIRLAVLVDRGGRELPIRPDFAALTLEVPPHQNINLSRLDDGHLT
LSLA

Sequences:

>Translated_164_residues
MHASLPDANTLIARLAESIAPTFAPETVIVGIHSGGVWVAERLHALLKCASPVGALDISFYRDDFSRIGLHPQVKPSNLP
FDLENRVILLVDDVLHTGRTVRAAMNELFDYGRPASIRLAVLVDRGGRELPIRPDFAALTLEVPPHQNINLSRLDDGHLT
LSLA
>Mature_164_residues
MHASLPDANTLIARLAESIAPTFAPETVIVGIHSGGVWVAERLHALLKCASPVGALDISFYRDDFSRIGLHPQVKPSNLP
FDLENRVILLVDDVLHTGRTVRAAMNELFDYGRPASIRLAVLVDRGGRELPIRPDFAALTLEVPPHQNINLSRLDDGHLT
LSLA

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 17911; Mature: 17911

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHASLPDANTLIARLAESIAPTFAPETVIVGIHSGGVWVAERLHALLKCASPVGALDISF
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEE
YRDDFSRIGLHPQVKPSNLPFDLENRVILLVDDVLHTGRTVRAAMNELFDYGRPASIRLA
EHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECHHHCCHHHHHHHHHHHHCCCCCCEEEE
VLVDRGGRELPIRPDFAALTLEVPPHQNINLSRLDDGHLTLSLA
EEEECCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEC
>Mature Secondary Structure
MHASLPDANTLIARLAESIAPTFAPETVIVGIHSGGVWVAERLHALLKCASPVGALDISF
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEE
YRDDFSRIGLHPQVKPSNLPFDLENRVILLVDDVLHTGRTVRAAMNELFDYGRPASIRLA
EHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECHHHCCHHHHHHHHHHHHCCCCCCEEEE
VLVDRGGRELPIRPDFAALTLEVPPHQNINLSRLDDGHLTLSLA
EEEECCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA