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The map label for this gene is glyQ

Identifier: 74318366

GI number: 74318366

Start: 2422164

End: 2423102

Strand: Reverse

Name: glyQ

Synonym: Tbd_2348

Alternate gene names: 74318366

Gene position: 2423102-2422164 (Counterclockwise)

Preceding gene: 74318367

Following gene: 74318365

Centisome position: 83.27

GC content: 65.6

Gene sequence:

>939_bases
GTGAACCCCACCTTTCAGGACATCATCCTCACCCTTCAGCGTTATTGGGGCGAGCGCGGGTGCGCGCTGCTGCAGCCCTA
CGACATGGAAGTCGGCGCCGGCACGTCGCACACCGCGACCTTCCTGCGCGCGCTCGGTCCCGAGCCCTGGAAGGCCGCCT
ACGTGCAGCCCTCGCGCCGTCCCAAGGACGGCCGCTACGGCGAAAATCCCAACCGGCTGCAGCATTACTACCAGTTCCAG
GTCGTTCTCAAGCCCGCGCCGGCCGACATCCTCGAGCTCTACCTCGGTTCGCTCGAGGCGCTCGGCTTCGACCTGAGGAA
AAACGACGTGCGCTTCGTCGAGGACGACTGGGAAAACCCGACCCTCGGCGCCTGGGGGCTCGGCTGGGAGGTCTGGCTGA
ACGGCATGGAAGTTACCCAGTTCACCTACTTCCAGCAGGTCGGCGGCATCGACTGCAAGCCGATCACGGGCGAAATCACC
TACGGCCTCGAGCGCCTCGCGATGTACCTGCAGGGCGTCGAGAGCGTGTTCGACCTGAGATGGACCGACGGACTCACCTA
TCGGGACGTCTACCACCAGAACGAGGTCGAGCAGAGCGCCTACAACTTCGAGCACAGCGACGTCGGCTTCCTGCTGACCG
CCTTCAGCGCGCACGAAAAGAAGGCCCAGGAACTGATGGTCGCGCAGCTCGCGCTGCCGGCCTACGAACAGGTGCTCAAA
GCCGCGCACACCTTCAACCTGCTCGACGCCCGCGGCGCGATTTCGGTGACCGAGCGCGCCGCGTACATCGGCCGCATCCG
CAACCTCGCGCGCAGCGTCGCGAAGAGCTATCTCGACAGCCGGGCGCGCCTCGGCTTCCCGATGGCGCCCCGTGCCTGGG
CCGACGAAGTGCTCGCGAACATCGAAAAACAGACGCAAAAGAAGGCGGCCGCCGCATGA

Upstream 100 bases:

>100_bases
ATCCGGGCGCGTGCGTTCGCCGGTCCAAACTTTGCGCCGCCCTTAGAAACGCCCGTCAGGCACGGTAAAATGCGGCTTTC
CCGAAAAGCCTGCATTGCCC

Downstream 100 bases:

>100_bases
CCACCGCGAACCTGCTCGTTGAACTCTTCGTCGAGGAATTGCCGCCCAAGGCGCTGAAGAAGCTGGGCGAGGCTTTTGCC
GCCGCGCTGACCGAGAGCCT

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MNPTFQDIILTLQRYWGERGCALLQPYDMEVGAGTSHTATFLRALGPEPWKAAYVQPSRRPKDGRYGENPNRLQHYYQFQ
VVLKPAPADILELYLGSLEALGFDLRKNDVRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPITGEIT
YGLERLAMYLQGVESVFDLRWTDGLTYRDVYHQNEVEQSAYNFEHSDVGFLLTAFSAHEKKAQELMVAQLALPAYEQVLK
AAHTFNLLDARGAISVTERAAYIGRIRNLARSVAKSYLDSRARLGFPMAPRAWADEVLANIEKQTQKKAAAA

Sequences:

>Translated_312_residues
MNPTFQDIILTLQRYWGERGCALLQPYDMEVGAGTSHTATFLRALGPEPWKAAYVQPSRRPKDGRYGENPNRLQHYYQFQ
VVLKPAPADILELYLGSLEALGFDLRKNDVRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPITGEIT
YGLERLAMYLQGVESVFDLRWTDGLTYRDVYHQNEVEQSAYNFEHSDVGFLLTAFSAHEKKAQELMVAQLALPAYEQVLK
AAHTFNLLDARGAISVTERAAYIGRIRNLARSVAKSYLDSRARLGFPMAPRAWADEVLANIEKQTQKKAAAA
>Mature_312_residues
MNPTFQDIILTLQRYWGERGCALLQPYDMEVGAGTSHTATFLRALGPEPWKAAYVQPSRRPKDGRYGENPNRLQHYYQFQ
VVLKPAPADILELYLGSLEALGFDLRKNDVRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPITGEIT
YGLERLAMYLQGVESVFDLRWTDGLTYRDVYHQNEVEQSAYNFEHSDVGFLLTAFSAHEKKAQELMVAQLALPAYEQVLK
AAHTFNLLDARGAISVTERAAYIGRIRNLARSVAKSYLDSRARLGFPMAPRAWADEVLANIEKQTQKKAAAA

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=294, Percent_Identity=71.4285714285714, Blast_Score=442, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_THIDA (Q3SGE9)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_316106.1
- HSSP:   Q9WY59
- ProteinModelPortal:   Q3SGE9
- SMR:   Q3SGE9
- STRING:   Q3SGE9
- GeneID:   3673476
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2348
- NMPDR:   fig|292415.3.peg.2421
- eggNOG:   COG0752
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- PhylomeDB:   Q3SGE9
- ProtClustDB:   PRK09348
- BioCyc:   TDEN292415:TBD_2348-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 35351; Mature: 35351

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPTFQDIILTLQRYWGERGCALLQPYDMEVGAGTSHTATFLRALGPEPWKAAYVQPSRR
CCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCCCC
PKDGRYGENPNRLQHYYQFQVVLKPAPADILELYLGSLEALGFDLRKNDVRFVEDDWENP
CCCCCCCCCHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCC
TLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPITGEITYGLERLAMYLQGVESVFDLR
CCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WTDGLTYRDVYHQNEVEQSAYNFEHSDVGFLLTAFSAHEKKAQELMVAQLALPAYEQVLK
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHTFNLLDARGAISVTERAAYIGRIRNLARSVAKSYLDSRARLGFPMAPRAWADEVLAN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IEKQTQKKAAAA
HHHHHHHHHCCC
>Mature Secondary Structure
MNPTFQDIILTLQRYWGERGCALLQPYDMEVGAGTSHTATFLRALGPEPWKAAYVQPSRR
CCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCCCC
PKDGRYGENPNRLQHYYQFQVVLKPAPADILELYLGSLEALGFDLRKNDVRFVEDDWENP
CCCCCCCCCHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCC
TLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPITGEITYGLERLAMYLQGVESVFDLR
CCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WTDGLTYRDVYHQNEVEQSAYNFEHSDVGFLLTAFSAHEKKAQELMVAQLALPAYEQVLK
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHTFNLLDARGAISVTERAAYIGRIRNLARSVAKSYLDSRARLGFPMAPRAWADEVLAN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IEKQTQKKAAAA
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA