Click here to switch to the map view.

The map label for this gene is gufA [H]

Identifier: 74318342

GI number: 74318342

Start: 2398818

End: 2399735

Strand: Direct

Name: gufA [H]

Synonym: Tbd_2324

Alternate gene names: 74318342

Gene position: 2398818-2399735 (Clockwise)

Preceding gene: 74318336

Following gene: 74318346

Centisome position: 82.44

GC content: 72.0

Gene sequence:

>918_bases
ATGAACACCCGGGCCCGCAGCGTGCAGCGTTTCCTGACCGACCCGGGTCGCACTGCCGCCGTGCGGCGCCTGGGGACGGC
GCTCGCGCTCGCGCTGCTCGGCGGCCTGGTCTGGGTCGCCTGGGTTCACGGCCGCGGGGGGCTCGGTACGCCGATGGGCC
TGGCCCTGGCCGGCTCAGGCGTCGCCGCGCTCGCCACCGCCGTGGGTGCGCTGCCCGCGCTCTTCATTCGCCGGATCTCG
CCGCGCTGGGAAGACGTCATGCTGGGTTTTGGCGCCGGGGTCATGATCGCCGCCGCCTGCTTCTCGCTGATCGTGCCGGG
AGTCGCGGCGGGTACCGAGACGACCGGGAGTCGCGCCGGCGGCGCTACGCTGGTCGCCGCGGGGCTCGTCCTCGGCGCCC
TATTCCTGCTGCTCGCCGACCGGGTCGTGCCGCACGAACACCCGCAAGCAGGCCGCCACGGGCCAGAGTGGGTGCATCTG
CGCCGGGTGTGGCTGATGGTCTTCGCCATCGCGCTGCATAATTTTCCGGAGGGAATGGCGATCGGGGTCGGCTTCTCGGG
CGGAGACCCGGCGGTCGGCGTGCCCTTGACCGCGGCGATCGCGATCCAGGACATCCCCGAGGGACTGGTCGTCGCCGTGG
CCTTGCGCACGGTCGCCTATCTGCCCTGGCGGGCGACGCTCGCGGCGGCGCTCACCGGGCTCGCCGAGCCGCTCGGCGCG
ATCGTCGGGGTCGCGCTGACGAGCGGGTTCGCGCCGCTTTATCCCTTGGGCCTGGGCTTTGCGGCCGGCGCGATGATCTG
GGTCGTGTCGCACGAGATCGTGCCCGAGACCCATCGCAAGGGGCACGAGCAGGCCGCGACGCTCGGCCTCATCGGCGGTT
TTGTGTTGATGATGATGCTGGACACAGCGCTTGGTTAG

Upstream 100 bases:

>100_bases
GAGCGTCATGCGGACGGTCGGTTAAGGCGATCGGCCTATTCTAGCCCTCCCCGCCGGTTCCCCCTGCGCGTGCCAGGGCG
CGCTCGGCTAAATTGAAGCC

Downstream 100 bases:

>100_bases
ACGCGCGCACCGCCGCGCCCGGCGCGGACTCGGTGGCCTGCGCCTGCGAGGGCGTTCCGGCTTCCTGCTGATGTTGATGA
CCCAGGGCGAGCGCGTAGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNTRARSVQRFLTDPGRTAAVRRLGTALALALLGGLVWVAWVHGRGGLGTPMGLALAGSGVAALATAVGALPALFIRRIS
PRWEDVMLGFGAGVMIAAACFSLIVPGVAAGTETTGSRAGGATLVAAGLVLGALFLLLADRVVPHEHPQAGRHGPEWVHL
RRVWLMVFAIALHNFPEGMAIGVGFSGGDPAVGVPLTAAIAIQDIPEGLVVAVALRTVAYLPWRATLAAALTGLAEPLGA
IVGVALTSGFAPLYPLGLGFAAGAMIWVVSHEIVPETHRKGHEQAATLGLIGGFVLMMMLDTALG

Sequences:

>Translated_305_residues
MNTRARSVQRFLTDPGRTAAVRRLGTALALALLGGLVWVAWVHGRGGLGTPMGLALAGSGVAALATAVGALPALFIRRIS
PRWEDVMLGFGAGVMIAAACFSLIVPGVAAGTETTGSRAGGATLVAAGLVLGALFLLLADRVVPHEHPQAGRHGPEWVHL
RRVWLMVFAIALHNFPEGMAIGVGFSGGDPAVGVPLTAAIAIQDIPEGLVVAVALRTVAYLPWRATLAAALTGLAEPLGA
IVGVALTSGFAPLYPLGLGFAAGAMIWVVSHEIVPETHRKGHEQAATLGLIGGFVLMMMLDTALG
>Mature_305_residues
MNTRARSVQRFLTDPGRTAAVRRLGTALALALLGGLVWVAWVHGRGGLGTPMGLALAGSGVAALATAVGALPALFIRRIS
PRWEDVMLGFGAGVMIAAACFSLIVPGVAAGTETTGSRAGGATLVAAGLVLGALFLLLADRVVPHEHPQAGRHGPEWVHL
RRVWLMVFAIALHNFPEGMAIGVGFSGGDPAVGVPLTAAIAIQDIPEGLVVAVALRTVAYLPWRATLAAALTGLAEPLGA
IVGVALTSGFAPLYPLGLGFAAGAMIWVVSHEIVPETHRKGHEQAATLGLIGGFVLMMMLDTALG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577422, Length=169, Percent_Identity=39.0532544378698, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI229577418, Length=169, Percent_Identity=39.0532544378698, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1789419, Length=245, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17507805, Length=302, Percent_Identity=31.1258278145695, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24652846, Length=169, Percent_Identity=39.6449704142012, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 31192; Mature: 31192

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRARSVQRFLTDPGRTAAVRRLGTALALALLGGLVWVAWVHGRGGLGTPMGLALAGSG
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCC
VAALATAVGALPALFIRRISPRWEDVMLGFGAGVMIAAACFSLIVPGVAAGTETTGSRAG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GATLVAAGLVLGALFLLLADRVVPHEHPQAGRHGPEWVHLRRVWLMVFAIALHNFPEGMA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCE
IGVGFSGGDPAVGVPLTAAIAIQDIPEGLVVAVALRTVAYLPWRATLAAALTGLAEPLGA
EEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IVGVALTSGFAPLYPLGLGFAAGAMIWVVSHEIVPETHRKGHEQAATLGLIGGFVLMMML
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHH
DTALG
HHHCC
>Mature Secondary Structure
MNTRARSVQRFLTDPGRTAAVRRLGTALALALLGGLVWVAWVHGRGGLGTPMGLALAGSG
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCC
VAALATAVGALPALFIRRISPRWEDVMLGFGAGVMIAAACFSLIVPGVAAGTETTGSRAG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GATLVAAGLVLGALFLLLADRVVPHEHPQAGRHGPEWVHLRRVWLMVFAIALHNFPEGMA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCE
IGVGFSGGDPAVGVPLTAAIAIQDIPEGLVVAVALRTVAYLPWRATLAAALTGLAEPLGA
EEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IVGVALTSGFAPLYPLGLGFAAGAMIWVVSHEIVPETHRKGHEQAATLGLIGGFVLMMML
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHH
DTALG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]