Click here to switch to the map view.

The map label for this gene is ytfL [C]

Identifier: 74318331

GI number: 74318331

Start: 2387552

End: 2388868

Strand: Direct

Name: ytfL [C]

Synonym: Tbd_2313

Alternate gene names: 74318331

Gene position: 2387552-2388868 (Clockwise)

Preceding gene: 74318330

Following gene: 74318336

Centisome position: 82.05

GC content: 69.02

Gene sequence:

>1317_bases
ATGGAAATCCTGCTGTTGACCGGCCTGATTCTGCTGAACGGCGCCTTGGCCATGTCCGAGATCGCGCTGATCACCGCGCG
CCGCGGGCGCCTCGTTCGACTCGCCGAGGACGGCAGCGCTGCGGCCGCGGTCGCCCTGCGCCTGCACGACGACCCGACGC
GCTTCCTGTCCACCGTGCAGGTCGGCATCACCTCGATCGGCATCCTCAACGGCATGATCGGCCAGGCGGTGCTCGCGGAG
CCCTTGGCGCGGTGGCTGCATTCCCTCGGCGTCGAGGCCGAGGTCGGTGGGGTCGCCGCGACCGCGCTCGTCGTCCTCGT
CGTCACCTATGTCTCGATCGTCATCGGCGAACTGGTGCCCAAGCGCATTGCGCAGTTCAACCCCGAGAGCGTCGCCCGCC
GCGTCGCGCGGCCGATGCAGGCGCTGGCCCTGCTGGCGCAGCCCTTCGTGCGGCTGCTCTCGGTGTCGACCGATACGATC
CTGCGCCTGCTCGGCAAGCAGGCCGCGAGCCAGAGCGACGTCATCGAGGAGGAAATCCACGCGCTGCTCGACGAGGGCTC
GGAATCGGGCGCGATCGAGCGGCAGGAGCGCGAGATGGTGCGCAACGTCTTCCGCCTCGACGAGCGCCATATCCATTCGC
TCATGGTGCCGCGTGCCGACATCGTCTACCTCGACGTCACGCTGCCGCTCGAGGAAAACCTGCGACGTGTCGCCGACTCC
GAGCACTCGCGCTTTCCGGTCTGCCGCGGCGGCCTCGACGAGGTGCTCGGCGTCGTCACCGCCCGGCAACTGCTCCAGCA
GACGCTGCAGCGGGGCCGGCCCGATCTCGGCGGGCAGCTGAGCCCGGCCGTCTACGTGCCCGAGAGCCTGACCGGCATGG
ACCTGCTCGAGCAGTTCCGCGCCTCCGACGCGCACATGGTGCTCGTGATCGACGAATACGGCGAAATCAACGGCCTCGTC
ACGCTGCAGGACGTGCTCGAGGCGGTGACCGGCGAATTCACGCCGCGCAACCTCGACGAGGCGTGGGCGGTGCAGCGGGC
CGACGGCTCGTGGCTGCTCGACGGGCTGATCCCGATCCCCGAGCTGAAGGACCGCCTCGATCTGAAAAGCGTGCCCGATG
AAAGCCGTGGCCGCTACCACACCCTGAGCGGCATGGTCATGTGGCTGTCGGGACACCTGCCGCAGACCGGCGACGTCGTG
GACTGGGAAGACTGGCGGCTCGAACTGATCGACCTCGACGGCAAGCGCATCGACAAGGTGCTGGCGACGCGTCTGCCAGA
TGCGCCGGCCGGCACTGCGGCCCCCGACGCACGTTGA

Upstream 100 bases:

>100_bases
GCCTTGTTTTTTTCCCCAGCGGGGTCGGGCGTTCTTTCGTGTCGGCGCCCGCCGGGCCGACCGCTGCTATCGTTTCGCCA
CTCCCCTTCGAGACCCGACC

Downstream 100 bases:

>100_bases
GGCAAGGACCGCCGCCGCGCTAGGAAGCGGTCGGCTCGCCGCGGTAGATGCAGCCCGAGTCGTGGGTCTCCATGACCCGG
ATCTGTGACAGGCCGGGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MEILLLTGLILLNGALAMSEIALITARRGRLVRLAEDGSAAAAVALRLHDDPTRFLSTVQVGITSIGILNGMIGQAVLAE
PLARWLHSLGVEAEVGGVAATALVVLVVTYVSIVIGELVPKRIAQFNPESVARRVARPMQALALLAQPFVRLLSVSTDTI
LRLLGKQAASQSDVIEEEIHALLDEGSESGAIERQEREMVRNVFRLDERHIHSLMVPRADIVYLDVTLPLEENLRRVADS
EHSRFPVCRGGLDEVLGVVTARQLLQQTLQRGRPDLGGQLSPAVYVPESLTGMDLLEQFRASDAHMVLVIDEYGEINGLV
TLQDVLEAVTGEFTPRNLDEAWAVQRADGSWLLDGLIPIPELKDRLDLKSVPDESRGRYHTLSGMVMWLSGHLPQTGDVV
DWEDWRLELIDLDGKRIDKVLATRLPDAPAGTAAPDAR

Sequences:

>Translated_438_residues
MEILLLTGLILLNGALAMSEIALITARRGRLVRLAEDGSAAAAVALRLHDDPTRFLSTVQVGITSIGILNGMIGQAVLAE
PLARWLHSLGVEAEVGGVAATALVVLVVTYVSIVIGELVPKRIAQFNPESVARRVARPMQALALLAQPFVRLLSVSTDTI
LRLLGKQAASQSDVIEEEIHALLDEGSESGAIERQEREMVRNVFRLDERHIHSLMVPRADIVYLDVTLPLEENLRRVADS
EHSRFPVCRGGLDEVLGVVTARQLLQQTLQRGRPDLGGQLSPAVYVPESLTGMDLLEQFRASDAHMVLVIDEYGEINGLV
TLQDVLEAVTGEFTPRNLDEAWAVQRADGSWLLDGLIPIPELKDRLDLKSVPDESRGRYHTLSGMVMWLSGHLPQTGDVV
DWEDWRLELIDLDGKRIDKVLATRLPDAPAGTAAPDAR
>Mature_438_residues
MEILLLTGLILLNGALAMSEIALITARRGRLVRLAEDGSAAAAVALRLHDDPTRFLSTVQVGITSIGILNGMIGQAVLAE
PLARWLHSLGVEAEVGGVAATALVVLVVTYVSIVIGELVPKRIAQFNPESVARRVARPMQALALLAQPFVRLLSVSTDTI
LRLLGKQAASQSDVIEEEIHALLDEGSESGAIERQEREMVRNVFRLDERHIHSLMVPRADIVYLDVTLPLEENLRRVADS
EHSRFPVCRGGLDEVLGVVTARQLLQQTLQRGRPDLGGQLSPAVYVPESLTGMDLLEQFRASDAHMVLVIDEYGEINGLV
TLQDVLEAVTGEFTPRNLDEAWAVQRADGSWLLDGLIPIPELKDRLDLKSVPDESRGRYHTLSGMVMWLSGHLPQTGDVV
DWEDWRLELIDLDGKRIDKVLATRLPDAPAGTAAPDAR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=379, Percent_Identity=26.9129287598945, Blast_Score=163, Evalue=3e-40,
Organism=Escherichia coli, GI1790664, Length=435, Percent_Identity=30.8045977011494, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI145693175, Length=410, Percent_Identity=26.3414634146341, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI87082033, Length=271, Percent_Identity=33.210332103321, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788119, Length=383, Percent_Identity=30.8093994778068, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1786879, Length=256, Percent_Identity=29.296875, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47912; Mature: 47912

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILLLTGLILLNGALAMSEIALITARRGRLVRLAEDGSAAAAVALRLHDDPTRFLSTVQ
CCHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHH
VGITSIGILNGMIGQAVLAEPLARWLHSLGVEAEVGGVAATALVVLVVTYVSIVIGELVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KRIAQFNPESVARRVARPMQALALLAQPFVRLLSVSTDTILRLLGKQAASQSDVIEEEIH
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHH
ALLDEGSESGAIERQEREMVRNVFRLDERHIHSLMVPRADIVYLDVTLPLEENLRRVADS
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCC
EHSRFPVCRGGLDEVLGVVTARQLLQQTLQRGRPDLGGQLSPAVYVPESLTGMDLLEQFR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHHHHC
ASDAHMVLVIDEYGEINGLVTLQDVLEAVTGEFTPRNLDEAWAVQRADGSWLLDGLIPIP
CCCCEEEEEEECCCCCCCEEEHHHHHHHHCCCCCCCCCHHHHHEECCCCCEEECCCCCCH
ELKDRLDLKSVPDESRGRYHTLSGMVMWLSGHLPQTGDVVDWEDWRLELIDLDGKRIDKV
HHHHHCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHH
LATRLPDAPAGTAAPDAR
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEILLLTGLILLNGALAMSEIALITARRGRLVRLAEDGSAAAAVALRLHDDPTRFLSTVQ
CCHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHH
VGITSIGILNGMIGQAVLAEPLARWLHSLGVEAEVGGVAATALVVLVVTYVSIVIGELVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KRIAQFNPESVARRVARPMQALALLAQPFVRLLSVSTDTILRLLGKQAASQSDVIEEEIH
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHH
ALLDEGSESGAIERQEREMVRNVFRLDERHIHSLMVPRADIVYLDVTLPLEENLRRVADS
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCC
EHSRFPVCRGGLDEVLGVVTARQLLQQTLQRGRPDLGGQLSPAVYVPESLTGMDLLEQFR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHHHHC
ASDAHMVLVIDEYGEINGLVTLQDVLEAVTGEFTPRNLDEAWAVQRADGSWLLDGLIPIP
CCCCEEEEEEECCCCCCCEEEHHHHHHHHCCCCCCCCCHHHHHEECCCCCEEECCCCCCH
ELKDRLDLKSVPDESRGRYHTLSGMVMWLSGHLPQTGDVVDWEDWRLELIDLDGKRIDKV
HHHHHCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHH
LATRLPDAPAGTAAPDAR
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]