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The map label for this gene is katE [H]

Identifier: 74318329

GI number: 74318329

Start: 2384338

End: 2386551

Strand: Direct

Name: katE [H]

Synonym: Tbd_2311

Alternate gene names: 74318329

Gene position: 2384338-2386551 (Clockwise)

Preceding gene: 74318322

Following gene: 74318330

Centisome position: 81.94

GC content: 67.03

Gene sequence:

>2214_bases
GTGCGGCGCCGATGCGCGCCCGGGTCCCGCGACGCCGCTTCAAGACAGTCGCCGCTGGCCGCCCGGCCTTGTCTAGCGCC
CCTGAGCGCCTATAAAGACGAGTCCAAGCGCACGTTCAGGAAAGCAACGATGAGCCAGAAAAAAAAGCCGGCGAAGGCCG
GCCCCGACGAAAATTTCGAGCGCGGCGCCGGGGGTGAAATCCACCAGACCGCCAACGGCGCGCATCCGCCGCTGACGACT
AACGACGGTGTACCGATTTCCGACGACCAGAATTCGCTGCGCAGCCACCCGCGCGGCCCGACGCTGCTCGAGGATTTCGT
CCTGCGCGACAAGATCACGCACTTCGACCACGAGCGCATTCCCGAACGCGTCGTCCACGCCCGCGGCAGCGCGGCGCACG
GCTACTTCGAACTGACCGAATCGCTCGAGAAATACACGACCGCGCGCATCCTCACCGAGGTCGGCGAGAAGACCCCGGTG
TTCACGCGGCTCTCGACCGTCGCCGGCGGCGCGGGCTCGGTCGACACGCCGCGCGACGTGCGCGGCTTCGCGGTCAAGTT
CTACACCAAGGAAGGCAACTGGGACCTCGTCGGCAACAACATCCCCGTGTTCTTCATCCAGGACGCGATCAAGTTTCCCG
ACCTCGTCCACTCGTTCAAGATGGAGCCCGACCGCGGCTTTCCGCAGTCGTCGACGGCGCACGACACCTTCTGGGACTAC
GTGTCGCTCACGCCCGAGTCCATGCACATGATTCTGTGGATCATGTCCGACCGCACGACGCCGCGCTCCCTGCGCATGAT
CGAGGCCTTCGGCGTGCACAGCTTCCGTCTCGTCAATGCGAAGGGCGCGTCGACCTTCGTCAAATTCCACTGGCGACCCA
AGCTCGGCCTGCAATCGACGATCTGGGACGAGACGGTCAAGATCGCCGGCGCCGACCCCGACTTCCACCGCCGCGACCTT
TTCGAGGCGATCAGCGAGGGCAATTTCCCGGAATGGGAGTTCGCCGTGCAGCTCTTCACCGAGGCCGACGCCGAGCGCTT
CCCCTTCGACCATCTCGACGCGACCAAGCTCATCCCCGAAGAACTCGTGCCGCTCAAGGTCATCGGCCGCATGGTGCTCG
ACCGCTGGCCGGACAATTTCTTCGCCGAGACCGAACAGGTCGCCTACTGCCCGACGCACGTCGTGCCCGGCATCGACTTT
TCCAACGACCCGCTGCTGCAGGGCCGGCTCTTCTCCTACGTCGACACCCAGTTGCTGCGCTTCAACTCGCCGAATTTCCA
CCAGGTGCCGGTCAACATGCCGAAGTGCCCGTTCGCCAACCTGCAGCGCGACGGCCACATGCAGATGGAGCGGCCGAAGG
GGCGCGTGAACTACGAACCCAACACGCTCGGCACGGACACGCCGCGCGAGACGCCGCAAGGCTTCCGCAGCGCGGCCGTG
ACCGAAAGCGGCGAGAAGGGCCGCATCCGCGCCGAGCGTTTCGCCGACCACTACAGCCAGGCGCGCCAGTTCTACGTCAG
CCAGACCGAATACGAGCAGGCGCATATCGCGTCGACGCTCGTGTTCGAGCTCGCCAAGGTCGACCACGTTCACATCCGCG
AGGCGATGGTCGGGCATTTGCGTCATGTCGACGAGGACCTCGCGCACCGCGTCGCGAAGGGGCTCGGCATCGATCCCTTG
CCGCCGGCGCCCGAGGCCGCCGCGCCCGTGCAGGACCTGCCGCCCTCGCCCGCCCTGCAGATCATCGGCAACATGAAGGA
CACGCTCGAAGGGCGCATGGTCGGCATCCTCGTCGGCGACGGCTCCGACGGCGCGCGCGTCGAGGCGCTGCGCCGGGCCG
CGACGGACGCCGGCGCCGCCGTGAAGATCATCGCCGCGCACGTCGGTCAGGTGAAGCTCGCCAACGGCAAGATGCTCAAG
GTCGACAAGCAGCTCGCCGGAACGCCGTCGGTCCTCTTCGACGCCGTGGCCGTCGTCGTCTCCGAGGACGCCGCGAAGAT
GCTGCTGAAGGAGAGCGCGGCGCTCGATTTCGTCCACGACGCGTTCGGCCACCTCAAGGCGATCGCGAGCGACGCGGGCG
GCCAGGCGCTGCTCGACGCCGTCCACGTCGTGCGCGACGCGGGTGTCGTCGATGCGGCCGACGTCGGCGCCTTCATCGCC
GCGGCAAAAACGCGGCAGTGGGACCGCGAACCGTCGGTGCGACTACTCGCGTGA

Upstream 100 bases:

>100_bases
CCGCGGTATCGCGCAAATTCAAGGACTTGGCGGAAGCGAGCCGGCGCCGGCGCGCGCCCTCGGTGCGCCTCGGGGGGCGC
GCGCCGCAAATTGGTGCGAG

Downstream 100 bases:

>100_bases
GCGCACGGCGCGCGGCGGAATAGCGCGGAGCGCGCGTCAACCTGCGCGCCGCGCAAAAGGCCTTGAGGGATTTTCGGCCC
GTTGCGCGGGGCAGGCGATA

Product: catalase

Products: NA

Alternate protein names: KAT2 [H]

Number of amino acids: Translated: 737; Mature: 737

Protein sequence:

>737_residues
MRRRCAPGSRDAASRQSPLAARPCLAPLSAYKDESKRTFRKATMSQKKKPAKAGPDENFERGAGGEIHQTANGAHPPLTT
NDGVPISDDQNSLRSHPRGPTLLEDFVLRDKITHFDHERIPERVVHARGSAAHGYFELTESLEKYTTARILTEVGEKTPV
FTRLSTVAGGAGSVDTPRDVRGFAVKFYTKEGNWDLVGNNIPVFFIQDAIKFPDLVHSFKMEPDRGFPQSSTAHDTFWDY
VSLTPESMHMILWIMSDRTTPRSLRMIEAFGVHSFRLVNAKGASTFVKFHWRPKLGLQSTIWDETVKIAGADPDFHRRDL
FEAISEGNFPEWEFAVQLFTEADAERFPFDHLDATKLIPEELVPLKVIGRMVLDRWPDNFFAETEQVAYCPTHVVPGIDF
SNDPLLQGRLFSYVDTQLLRFNSPNFHQVPVNMPKCPFANLQRDGHMQMERPKGRVNYEPNTLGTDTPRETPQGFRSAAV
TESGEKGRIRAERFADHYSQARQFYVSQTEYEQAHIASTLVFELAKVDHVHIREAMVGHLRHVDEDLAHRVAKGLGIDPL
PPAPEAAAPVQDLPPSPALQIIGNMKDTLEGRMVGILVGDGSDGARVEALRRAATDAGAAVKIIAAHVGQVKLANGKMLK
VDKQLAGTPSVLFDAVAVVVSEDAAKMLLKESAALDFVHDAFGHLKAIASDAGGQALLDAVHVVRDAGVVDAADVGAFIA
AAKTRQWDREPSVRLLA

Sequences:

>Translated_737_residues
MRRRCAPGSRDAASRQSPLAARPCLAPLSAYKDESKRTFRKATMSQKKKPAKAGPDENFERGAGGEIHQTANGAHPPLTT
NDGVPISDDQNSLRSHPRGPTLLEDFVLRDKITHFDHERIPERVVHARGSAAHGYFELTESLEKYTTARILTEVGEKTPV
FTRLSTVAGGAGSVDTPRDVRGFAVKFYTKEGNWDLVGNNIPVFFIQDAIKFPDLVHSFKMEPDRGFPQSSTAHDTFWDY
VSLTPESMHMILWIMSDRTTPRSLRMIEAFGVHSFRLVNAKGASTFVKFHWRPKLGLQSTIWDETVKIAGADPDFHRRDL
FEAISEGNFPEWEFAVQLFTEADAERFPFDHLDATKLIPEELVPLKVIGRMVLDRWPDNFFAETEQVAYCPTHVVPGIDF
SNDPLLQGRLFSYVDTQLLRFNSPNFHQVPVNMPKCPFANLQRDGHMQMERPKGRVNYEPNTLGTDTPRETPQGFRSAAV
TESGEKGRIRAERFADHYSQARQFYVSQTEYEQAHIASTLVFELAKVDHVHIREAMVGHLRHVDEDLAHRVAKGLGIDPL
PPAPEAAAPVQDLPPSPALQIIGNMKDTLEGRMVGILVGDGSDGARVEALRRAATDAGAAVKIIAAHVGQVKLANGKMLK
VDKQLAGTPSVLFDAVAVVVSEDAAKMLLKESAALDFVHDAFGHLKAIASDAGGQALLDAVHVVRDAGVVDAADVGAFIA
AAKTRQWDREPSVRLLA
>Mature_737_residues
MRRRCAPGSRDAASRQSPLAARPCLAPLSAYKDESKRTFRKATMSQKKKPAKAGPDENFERGAGGEIHQTANGAHPPLTT
NDGVPISDDQNSLRSHPRGPTLLEDFVLRDKITHFDHERIPERVVHARGSAAHGYFELTESLEKYTTARILTEVGEKTPV
FTRLSTVAGGAGSVDTPRDVRGFAVKFYTKEGNWDLVGNNIPVFFIQDAIKFPDLVHSFKMEPDRGFPQSSTAHDTFWDY
VSLTPESMHMILWIMSDRTTPRSLRMIEAFGVHSFRLVNAKGASTFVKFHWRPKLGLQSTIWDETVKIAGADPDFHRRDL
FEAISEGNFPEWEFAVQLFTEADAERFPFDHLDATKLIPEELVPLKVIGRMVLDRWPDNFFAETEQVAYCPTHVVPGIDF
SNDPLLQGRLFSYVDTQLLRFNSPNFHQVPVNMPKCPFANLQRDGHMQMERPKGRVNYEPNTLGTDTPRETPQGFRSAAV
TESGEKGRIRAERFADHYSQARQFYVSQTEYEQAHIASTLVFELAKVDHVHIREAMVGHLRHVDEDLAHRVAKGLGIDPL
PPAPEAAAPVQDLPPSPALQIIGNMKDTLEGRMVGILVGDGSDGARVEALRRAATDAGAAVKIIAAHVGQVKLANGKMLK
VDKQLAGTPSVLFDAVAVVVSEDAAKMLLKESAALDFVHDAFGHLKAIASDAGGQALLDAVHVVRDAGVVDAADVGAFIA
AAKTRQWDREPSVRLLA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions requ

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=476, Percent_Identity=42.6470588235294, Blast_Score=392, Evalue=1e-109,
Organism=Escherichia coli, GI48994891, Length=676, Percent_Identity=50.1479289940828, Blast_Score=654, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71998444, Length=481, Percent_Identity=41.3721413721414, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI25151141, Length=488, Percent_Identity=42.2131147540984, Blast_Score=377, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI25147792, Length=488, Percent_Identity=42.0081967213115, Blast_Score=377, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6320462, Length=397, Percent_Identity=41.5617128463476, Blast_Score=318, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6321525, Length=517, Percent_Identity=35.9767891682785, Blast_Score=300, Evalue=4e-82,
Organism=Drosophila melanogaster, GI17981717, Length=481, Percent_Identity=40.5405405405405, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI19920968, Length=432, Percent_Identity=40.2777777777778, Blast_Score=345, Evalue=9e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 81453; Mature: 81453

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRCAPGSRDAASRQSPLAARPCLAPLSAYKDESKRTFRKATMSQKKKPAKAGPDENFE
CCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
RGAGGEIHQTANGAHPPLTTNDGVPISDDQNSLRSHPRGPTLLEDFVLRDKITHFDHERI
CCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH
PERVVHARGSAAHGYFELTESLEKYTTARILTEVGEKTPVFTRLSTVAGGAGSVDTPRDV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCC
RGFAVKFYTKEGNWDLVGNNIPVFFIQDAIKFPDLVHSFKMEPDRGFPQSSTAHDTFWDY
CCEEEEEEEECCCEEEECCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
VSLTPESMHMILWIMSDRTTPRSLRMIEAFGVHSFRLVNAKGASTFVKFHWRPKLGLQST
HCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCCHH
IWDETVKIAGADPDFHRRDLFEAISEGNFPEWEFAVQLFTEADAERFPFDHLDATKLIPE
HHHHHEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCCCCHHHHCHH
ELVPLKVIGRMVLDRWPDNFFAETEQVAYCPTHVVPGIDFSNDPLLQGRLFSYVDTQLLR
HCCHHHHHHHHHHHHCCCHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
FNSPNFHQVPVNMPKCPFANLQRDGHMQMERPKGRVNYEPNTLGTDTPRETPQGFRSAAV
CCCCCCEECCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
TESGEKGRIRAERFADHYSQARQFYVSQTEYEQAHIASTLVFELAKVDHVHIREAMVGHL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RHVDEDLAHRVAKGLGIDPLPPAPEAAAPVQDLPPSPALQIIGNMKDTLEGRMVGILVGD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHCHHHHCCCEEEEEEEEC
GSDGARVEALRRAATDAGAAVKIIAAHVGQVKLANGKMLKVDKQLAGTPSVLFDAVAVVV
CCCCHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCCEEEECHHHCCCHHHHHHHHHHHH
SEDAAKMLLKESAALDFVHDAFGHLKAIASDAGGQALLDAVHVVRDAGVVDAADVGAFIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AAKTRQWDREPSVRLLA
HHHHHCCCCCCCCEECC
>Mature Secondary Structure
MRRRCAPGSRDAASRQSPLAARPCLAPLSAYKDESKRTFRKATMSQKKKPAKAGPDENFE
CCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
RGAGGEIHQTANGAHPPLTTNDGVPISDDQNSLRSHPRGPTLLEDFVLRDKITHFDHERI
CCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH
PERVVHARGSAAHGYFELTESLEKYTTARILTEVGEKTPVFTRLSTVAGGAGSVDTPRDV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCC
RGFAVKFYTKEGNWDLVGNNIPVFFIQDAIKFPDLVHSFKMEPDRGFPQSSTAHDTFWDY
CCEEEEEEEECCCEEEECCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
VSLTPESMHMILWIMSDRTTPRSLRMIEAFGVHSFRLVNAKGASTFVKFHWRPKLGLQST
HCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCCHH
IWDETVKIAGADPDFHRRDLFEAISEGNFPEWEFAVQLFTEADAERFPFDHLDATKLIPE
HHHHHEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCCCCHHHHCHH
ELVPLKVIGRMVLDRWPDNFFAETEQVAYCPTHVVPGIDFSNDPLLQGRLFSYVDTQLLR
HCCHHHHHHHHHHHHCCCHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
FNSPNFHQVPVNMPKCPFANLQRDGHMQMERPKGRVNYEPNTLGTDTPRETPQGFRSAAV
CCCCCCEECCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
TESGEKGRIRAERFADHYSQARQFYVSQTEYEQAHIASTLVFELAKVDHVHIREAMVGHL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RHVDEDLAHRVAKGLGIDPLPPAPEAAAPVQDLPPSPALQIIGNMKDTLEGRMVGILVGD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHCHHHHCCCEEEEEEEEC
GSDGARVEALRRAATDAGAAVKIIAAHVGQVKLANGKMLKVDKQLAGTPSVLFDAVAVVV
CCCCHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCCEEEECHHHCCCHHHHHHHHHHHH
SEDAAKMLLKESAALDFVHDAFGHLKAIASDAGGQALLDAVHVVRDAGVVDAADVGAFIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AAKTRQWDREPSVRLLA
HHHHHCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10198032; 11481431 [H]