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The map label for this gene is minE

Identifier: 74318322

GI number: 74318322

Start: 2376526

End: 2376780

Strand: Direct

Name: minE

Synonym: Tbd_2304

Alternate gene names: 74318322

Gene position: 2376526-2376780 (Clockwise)

Preceding gene: 74318321

Following gene: 74318329

Centisome position: 81.67

GC content: 59.22

Gene sequence:

>255_bases
ATGTCCTGGCTCTCCCTCATCTTCGGCGAAAAGAAATCGACCGCCTCGGTCGCCAAAGAGCGGCTGCAACTCATCATCGC
GCACGAGCGCGTCGGCCTGTCGGGCCGTGACTTCCTGCCCGACCTGCAGAAGGACCTGGTCGCGGTGATTTCGAAATACG
TCAAGATCGATCCCGACGACATCAAGGTCGGCCTCGAAAAACAGGGCAACTACGAGGTCATCGAGGTCAACATCGTGCTG
CCCGAGATGCGCTGA

Upstream 100 bases:

>100_bases
CTCGACGCGATCGCGCGTTTCCTCGGCGAACAACGCCCGCTGCGCTTCGTCGATTACGAGAAGCCCGGCCTCATCAAGCG
ACTATTCGGAGGCAAGTGAC

Downstream 100 bases:

>100_bases
TCCGCACGGTTCCCAATCTACGAACGGCCGCCCGAGCGCAGGCGGCTCACCGCTGAACCTTCGCGCTCACGGGCGACGGG
CTGACCGCCCCGCACCGCTT

Product: cell division topological specificity factor MinE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 84; Mature: 83

Protein sequence:

>84_residues
MSWLSLIFGEKKSTASVAKERLQLIIAHERVGLSGRDFLPDLQKDLVAVISKYVKIDPDDIKVGLEKQGNYEVIEVNIVL
PEMR

Sequences:

>Translated_84_residues
MSWLSLIFGEKKSTASVAKERLQLIIAHERVGLSGRDFLPDLQKDLVAVISKYVKIDPDDIKVGLEKQGNYEVIEVNIVL
PEMR
>Mature_83_residues
SWLSLIFGEKKSTASVAKERLQLIIAHERVGLSGRDFLPDLQKDLVAVISKYVKIDPDDIKVGLEKQGNYEVIEVNIVLP
EMR

Specific function: Prevents the cell division inhibition by proteins minC and minD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the l

COG id: COG0851

COG function: function code D; Septum formation topological specificity factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minE family

Homologues:

Organism=Escherichia coli, GI1787422, Length=83, Percent_Identity=45.7831325301205, Blast_Score=78, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINE_THIDA (Q3SGJ3)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_316062.1
- ProteinModelPortal:   Q3SGJ3
- SMR:   Q3SGJ3
- STRING:   Q3SGJ3
- GeneID:   3673432
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2304
- NMPDR:   fig|292415.3.peg.1651
- eggNOG:   COG0851
- HOGENOM:   HBG449956
- OMA:   AHERVEN
- PhylomeDB:   Q3SGJ3
- BioCyc:   TDEN292415:TBD_2304-MONOMER
- HAMAP:   MF_00262
- InterPro:   IPR005527
- TIGRFAMs:   TIGR01215

Pfam domain/function: PF03776 MinE

EC number: NA

Molecular weight: Translated: 9495; Mature: 9364

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLSLIFGEKKSTASVAKERLQLIIAHERVGLSGRDFLPDLQKDLVAVISKYVKIDPDD
CCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
IKVGLEKQGNYEVIEVNIVLPEMR
EEEEECCCCCEEEEEEEEEECCCC
>Mature Secondary Structure 
SWLSLIFGEKKSTASVAKERLQLIIAHERVGLSGRDFLPDLQKDLVAVISKYVKIDPDD
CHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
IKVGLEKQGNYEVIEVNIVLPEMR
EEEEECCCCCEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA