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The map label for this gene is cbbE [H]

Identifier: 74318248

GI number: 74318248

Start: 2309929

End: 2310612

Strand: Reverse

Name: cbbE [H]

Synonym: Tbd_2230

Alternate gene names: 74318248

Gene position: 2310612-2309929 (Counterclockwise)

Preceding gene: 74318251

Following gene: 74318247

Centisome position: 79.41

GC content: 64.91

Gene sequence:

>684_bases
ATGACGTACCGCATCGCCCCGTCCATTCTGTCCGCCAACTTCGCCCGCCTAGGCGAGGAGGTCGACAACGTGCTCGCGTC
CGGCGCCGACATCGTTCATTTCGATGTCATGGACAACCATTACGTGCCCAACCTCACGATCGGCCCGCTGGTGTGCGAAG
CGCTGCGCAAGCACGGCGTCACCGCACCGATCGACGTGCATCTCATGGTCAAGCCGGTCGACCGCATCATTCCCGACTTC
GCCAAGGCCGGCGCGACCTACATCACCTTCCACCCCGAAGCGTCGGAGCACATCGACCGCACCATCGGACTGATCAAGGA
AAACGGCTGCAAGGCCGGCCTCGTCTTCAACCCCGCGACGCCGCTCGACGTGCTCGAATACACGCTCGACAAGCTCGACA
TGGTGCTCCTGATGAGCGTGAACCCTGGCTTCGGCGGGCAGAAGTTCATCCCCTATGTGCTCGACAAGGCGCGCGCCGTG
CGCAAGATGATCGACGACCGCGGCCTCGACGTGAGCCTCGAGATCGACGGCGGCGTGGGCCCGGCCAACATCGCCGAAGT
CGCGCGCGCCGGCGTCGACACCTTCGTCGCCGGCTCGGCCGTGTTCGGCGCGGCCAAAGAGGGCGACCCGCAGCGCTATA
ACAGCATCATCGCCGCGATGCGCGCGGAGTTGGCGAAAGTGTAA

Upstream 100 bases:

>100_bases
TGCTGGGCTCCGCTCGACGGGATGGATCGCCGAGTGTAACGCAATGGGCCGGTGCACTTAAGCTAAAATGCGGGGTCGAC
AAAAATTCCGGAGCTCCCCC

Downstream 100 bases:

>100_bases
AACCGCAGGGGCCAGGATTCGGGGGTCAGGGGTCGGGGGGCTTTGTGCTTCGCGCCTTTCGAAATTGTGCGGCCGCAGGC
CGCTCGTCCCCTGAACCCCG

Product: ribulose-5-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTYRIAPSILSANFARLGEEVDNVLASGADIVHFDVMDNHYVPNLTIGPLVCEALRKHGVTAPIDVHLMVKPVDRIIPDF
AKAGATYITFHPEASEHIDRTIGLIKENGCKAGLVFNPATPLDVLEYTLDKLDMVLLMSVNPGFGGQKFIPYVLDKARAV
RKMIDDRGLDVSLEIDGGVGPANIAEVARAGVDTFVAGSAVFGAAKEGDPQRYNSIIAAMRAELAKV

Sequences:

>Translated_227_residues
MTYRIAPSILSANFARLGEEVDNVLASGADIVHFDVMDNHYVPNLTIGPLVCEALRKHGVTAPIDVHLMVKPVDRIIPDF
AKAGATYITFHPEASEHIDRTIGLIKENGCKAGLVFNPATPLDVLEYTLDKLDMVLLMSVNPGFGGQKFIPYVLDKARAV
RKMIDDRGLDVSLEIDGGVGPANIAEVARAGVDTFVAGSAVFGAAKEGDPQRYNSIIAAMRAELAKV
>Mature_226_residues
TYRIAPSILSANFARLGEEVDNVLASGADIVHFDVMDNHYVPNLTIGPLVCEALRKHGVTAPIDVHLMVKPVDRIIPDFA
KAGATYITFHPEASEHIDRTIGLIKENGCKAGLVFNPATPLDVLEYTLDKLDMVLLMSVNPGFGGQKFIPYVLDKARAVR
KMIDDRGLDVSLEIDGGVGPANIAEVARAGVDTFVAGSAVFGAAKEGDPQRYNSIIAAMRAELAKV

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=224, Percent_Identity=39.7321428571429, Blast_Score=160, Evalue=6e-40,
Organism=Homo sapiens, GI219879828, Length=224, Percent_Identity=37.9464285714286, Blast_Score=147, Evalue=6e-36,
Organism=Homo sapiens, GI24307923, Length=179, Percent_Identity=32.9608938547486, Blast_Score=94, Evalue=9e-20,
Organism=Escherichia coli, GI1789788, Length=225, Percent_Identity=70.2222222222222, Blast_Score=328, Evalue=3e-91,
Organism=Escherichia coli, GI1790523, Length=208, Percent_Identity=37.0192307692308, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1790754, Length=201, Percent_Identity=30.3482587064677, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=213, Percent_Identity=41.3145539906103, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6322341, Length=234, Percent_Identity=39.7435897435897, Blast_Score=162, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24586301, Length=204, Percent_Identity=39.2156862745098, Blast_Score=147, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24398; Mature: 24267

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRIAPSILSANFARLGEEVDNVLASGADIVHFDVMDNHYVPNLTIGPLVCEALRKHGV
CCEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCC
TAPIDVHLMVKPVDRIIPDFAKAGATYITFHPEASEHIDRTIGLIKENGCKAGLVFNPAT
CCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCC
PLDVLEYTLDKLDMVLLMSVNPGFGGQKFIPYVLDKARAVRKMIDDRGLDVSLEIDGGVG
HHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
PANIAEVARAGVDTFVAGSAVFGAAKEGDPQRYNSIIAAMRAELAKV
CHHHHHHHHHCHHHHHHCHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TYRIAPSILSANFARLGEEVDNVLASGADIVHFDVMDNHYVPNLTIGPLVCEALRKHGV
CEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCC
TAPIDVHLMVKPVDRIIPDFAKAGATYITFHPEASEHIDRTIGLIKENGCKAGLVFNPAT
CCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCC
PLDVLEYTLDKLDMVLLMSVNPGFGGQKFIPYVLDKARAVRKMIDDRGLDVSLEIDGGVG
HHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
PANIAEVARAGVDTFVAGSAVFGAAKEGDPQRYNSIIAAMRAELAKV
CHHHHHHHHHCHHHHHHCHHHCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]