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The map label for this gene is siaT [H]

Identifier: 74318169

GI number: 74318169

Start: 2237613

End: 2239007

Strand: Direct

Name: siaT [H]

Synonym: Tbd_2151

Alternate gene names: 74318169

Gene position: 2237613-2239007 (Clockwise)

Preceding gene: 74318168

Following gene: 74318170

Centisome position: 76.9

GC content: 68.53

Gene sequence:

>1395_bases
GTGACCGAGATCCTCGTACCGCTGATGTTCGTCGGGCTCGTCGCCTTTCTGCTGATCGGCTATCCGGTCGCGTTCGCGCT
CGCGGCGAACGGTCTGCTCTTCGCCGCGATCGGCATCGCCGCCGGCCTCTTCGACCTGTCGCTGCTGCACGCCTTGCCTG
AGCGCGTCTACGGCATCGTCGCCAATCCGACGCTGCTCGCGATACCGTTCTTCGCCCTGATGGGGTTGATCCTTGAGCGC
TCGGGCATGGCCGAGGACCTGCTCGATACGGTCGGCCAGCTGTTCGGCTCGGCGCGCGGCGGCCTCGCCTACGCGGTGGT
CCTGGTCGGCGGCCTGCTCGCCGCGACGACCGGCGTCGTCGCCGCGACCGTGATCGCGATGGGGCTGATCTCGCTGCCCG
TGATGCTGCGCTACGGCTACGACAAACGGCTCGCCGCGGGCGTCATCGCGGCGTCGGGCACGCTCGCGCAAATCATTCCG
CCATCGCTGGTCCTGATCGTGCTGGCCGACCAGCTCGGGACTTCGGTCGGCGCCATGTACAAAGGTGCGCTGGTCCCGGG
GCTCGTCCTCGTCGCGGCCTATCTGGCCTACGTGTTCGGCGTGAGCCTGCTGCGCCCGCACGCCGCCCCCGCAGTGCCGA
CGTCGGCGCGTACGCTGCGCGGATCGGCGCTCGCGCTGCGCGTGCTCACCACGCTGCTGCCGCCGCTGGTGCTCATCTTC
CTCGTGCTCGGCACGATTTTTCTCGGCGTCGCGACGCCGACCGAAGGCGGCGCGATGGGTGCGGTCGGCGCGCTCGCCCT
CGCCGCGGCGCGCGGACGCCTGACGCGGCTGCAGCTCACCCAAGCCGTCGACAGCACCACCCGGCTCACGACCTTCGTCA
TCTTCATCCTGATCGGCTCGACGATATTCACGCTCGTTTTCCGCGGGCTCGACGGCGACGCCGCGGTCGAGCACGTCTTC
GCCCAGCTGCCCGGCGGCGTCCTCGGCTTTCTCATCGTCGTCAACCTGCTGGTGTTCGTGCTCGCGTTCTTTCTCGACTT
TTTCGAGATCGCCTTCATCGTCGTCCCGCTCGTCGGCCCGGTCGCCGCCAAGCTCGGCATCGACCCGATCTGGTTCGGTG
TCATGCTCGCGGTCAACATGCAGACCGCGTTCATGCATCCGCCCTTCGGCTTCGCGCTGTTCTACCTCAAGAGCGTCGCG
CCGAAGGCGGTCCGCACCGGCGACATCTACCGCGGCGCGATTCCGTTTCTCGTCATCCAGCTCCTGATGGTCGCCGTCGT
CCTGGGTTTCCCGCAGATCGTCCTGCGCGACGTGGCGGGCGACGCGAGCAGCGTGCGCGAGATCCCGATCGACGTCGACC
CCGACGCCAACTATCTCCCCGCCGAGTGGCGCTGA

Upstream 100 bases:

>100_bases
CTCGCGCTGCAGGGTATCGCCGAAATCATCAAGCGCGTCGGCGTGCTGCGCGGCGATCTCGTGATGCCCGCGGAAGCGCC
CGACGAGGAGGTGTGACGAC

Downstream 100 bases:

>100_bases
GCGCTGCGCACGACCTGACGTTTCGCCCCGGAACCGTGAGAAAATGAACGGCTTCACGCGCGCTCGGTCATACGCGCGTC
GATCCGACTCCACTACTCCA

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTEILVPLMFVGLVAFLLIGYPVAFALAANGLLFAAIGIAAGLFDLSLLHALPERVYGIVANPTLLAIPFFALMGLILER
SGMAEDLLDTVGQLFGSARGGLAYAVVLVGGLLAATTGVVAATVIAMGLISLPVMLRYGYDKRLAAGVIAASGTLAQIIP
PSLVLIVLADQLGTSVGAMYKGALVPGLVLVAAYLAYVFGVSLLRPHAAPAVPTSARTLRGSALALRVLTTLLPPLVLIF
LVLGTIFLGVATPTEGGAMGAVGALALAAARGRLTRLQLTQAVDSTTRLTTFVIFILIGSTIFTLVFRGLDGDAAVEHVF
AQLPGGVLGFLIVVNLLVFVLAFFLDFFEIAFIVVPLVGPVAAKLGIDPIWFGVMLAVNMQTAFMHPPFGFALFYLKSVA
PKAVRTGDIYRGAIPFLVIQLLMVAVVLGFPQIVLRDVAGDASSVREIPIDVDPDANYLPAEWR

Sequences:

>Translated_464_residues
MTEILVPLMFVGLVAFLLIGYPVAFALAANGLLFAAIGIAAGLFDLSLLHALPERVYGIVANPTLLAIPFFALMGLILER
SGMAEDLLDTVGQLFGSARGGLAYAVVLVGGLLAATTGVVAATVIAMGLISLPVMLRYGYDKRLAAGVIAASGTLAQIIP
PSLVLIVLADQLGTSVGAMYKGALVPGLVLVAAYLAYVFGVSLLRPHAAPAVPTSARTLRGSALALRVLTTLLPPLVLIF
LVLGTIFLGVATPTEGGAMGAVGALALAAARGRLTRLQLTQAVDSTTRLTTFVIFILIGSTIFTLVFRGLDGDAAVEHVF
AQLPGGVLGFLIVVNLLVFVLAFFLDFFEIAFIVVPLVGPVAAKLGIDPIWFGVMLAVNMQTAFMHPPFGFALFYLKSVA
PKAVRTGDIYRGAIPFLVIQLLMVAVVLGFPQIVLRDVAGDASSVREIPIDVDPDANYLPAEWR
>Mature_463_residues
TEILVPLMFVGLVAFLLIGYPVAFALAANGLLFAAIGIAAGLFDLSLLHALPERVYGIVANPTLLAIPFFALMGLILERS
GMAEDLLDTVGQLFGSARGGLAYAVVLVGGLLAATTGVVAATVIAMGLISLPVMLRYGYDKRLAAGVIAASGTLAQIIPP
SLVLIVLADQLGTSVGAMYKGALVPGLVLVAAYLAYVFGVSLLRPHAAPAVPTSARTLRGSALALRVLTTLLPPLVLIFL
VLGTIFLGVATPTEGGAMGAVGALALAAARGRLTRLQLTQAVDSTTRLTTFVIFILIGSTIFTLVFRGLDGDAAVEHVFA
QLPGGVLGFLIVVNLLVFVLAFFLDFFEIAFIVVPLVGPVAAKLGIDPIWFGVMLAVNMQTAFMHPPFGFALFYLKSVAP
KAVRTGDIYRGAIPFLVIQLLMVAVVLGFPQIVLRDVAGDASSVREIPIDVDPDANYLPAEWR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=412, Percent_Identity=27.6699029126214, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 48505; Mature: 48374

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEILVPLMFVGLVAFLLIGYPVAFALAANGLLFAAIGIAAGLFDLSLLHALPERVYGIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANPTLLAIPFFALMGLILERSGMAEDLLDTVGQLFGSARGGLAYAVVLVGGLLAATTGVV
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AATVIAMGLISLPVMLRYGYDKRLAAGVIAASGTLAQIIPPSLVLIVLADQLGTSVGAMY
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCHHHHHHH
KGALVPGLVLVAAYLAYVFGVSLLRPHAAPAVPTSARTLRGSALALRVLTTLLPPLVLIF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVLGTIFLGVATPTEGGAMGAVGALALAAARGRLTRLQLTQAVDSTTRLTTFVIFILIGS
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIFTLVFRGLDGDAAVEHVFAQLPGGVLGFLIVVNLLVFVLAFFLDFFEIAFIVVPLVGP
HHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAKLGIDPIWFGVMLAVNMQTAFMHPPFGFALFYLKSVAPKAVRTGDIYRGAIPFLVIQ
HHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
LLMVAVVLGFPQIVLRDVAGDASSVREIPIDVDPDANYLPAEWR
HHHHHHHHCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEILVPLMFVGLVAFLLIGYPVAFALAANGLLFAAIGIAAGLFDLSLLHALPERVYGIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANPTLLAIPFFALMGLILERSGMAEDLLDTVGQLFGSARGGLAYAVVLVGGLLAATTGVV
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AATVIAMGLISLPVMLRYGYDKRLAAGVIAASGTLAQIIPPSLVLIVLADQLGTSVGAMY
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCHHHHHHH
KGALVPGLVLVAAYLAYVFGVSLLRPHAAPAVPTSARTLRGSALALRVLTTLLPPLVLIF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVLGTIFLGVATPTEGGAMGAVGALALAAARGRLTRLQLTQAVDSTTRLTTFVIFILIGS
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIFTLVFRGLDGDAAVEHVFAQLPGGVLGFLIVVNLLVFVLAFFLDFFEIAFIVVPLVGP
HHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAKLGIDPIWFGVMLAVNMQTAFMHPPFGFALFYLKSVAPKAVRTGDIYRGAIPFLVIQ
HHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
LLMVAVVLGFPQIVLRDVAGDASSVREIPIDVDPDANYLPAEWR
HHHHHHHHCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]