Click here to switch to the map view.

The map label for this gene is ilvH [H]

Identifier: 74318008

GI number: 74318008

Start: 2080648

End: 2081145

Strand: Reverse

Name: ilvH [H]

Synonym: Tbd_1990

Alternate gene names: 74318008

Gene position: 2081145-2080648 (Counterclockwise)

Preceding gene: 74318009

Following gene: 74318007

Centisome position: 71.52

GC content: 62.45

Gene sequence:

>498_bases
ATGAGCACCCGCCATATCATTTCGCTCTTGATGGAGAACGAGGCGGGTGCGCTGTCGCGCGTCGCCGGTCTCTTCTCCGC
GCGCGCCTACAACATCGAATCGCTCACGGTCGCACCGACCGAGGATGCCACGCTCTCGCGCATGACCATCGTCACGGTCG
GCTCGGAAGACATCATCGAGCAGATCACCAAGCAGCTGAACAAGCTCGTCGACGTCATCAAGGTCATGGATCTGACCGAA
GGCCGTCACATCGAGCGCGAGCTCATGCTGGTCAAGGTCAAGGCGACGGGCCTCGGGCGCGAGGAGATGAAGCGCACCGC
CGACATCTTCCGCGGGCGCATCATCGACGTCACCGATTCGACCTACACGATCGAACTGACCGGCACCGGTTCCAAGCTCG
ACGCCTTTCTCGAGGCGATCGATCCTGCCCTGATCATCGAGACCGTGCGCACCGGAGCGTCCGGCATCGGACGCGGTGAG
CGCAGCCTCAAAGTCTGA

Upstream 100 bases:

>100_bases
TGGTGTTCATGGACTTCCAGACCGACCAGACCGAGAACGTCTTCCCGATGGTCGAAGGCGGCAAGGGCCTGTCGGAAATG
ATTCTGGCGGAGGAGCTGTG

Downstream 100 bases:

>100_bases
TTTTCAATTCGCATTCATTTTTTTGCCCAGGAATTCACCATGAAAGTTTATTACGACAAGGACGCCGACCTTTCCCTCAT
CAAGCAGCGCAAGGTCGCGA

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: ALS-III; Acetohydroxy-acid synthase III small subunit; AHAS-III [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSTRHIISLLMENEAGALSRVAGLFSARAYNIESLTVAPTEDATLSRMTIVTVGSEDIIEQITKQLNKLVDVIKVMDLTE
GRHIERELMLVKVKATGLGREEMKRTADIFRGRIIDVTDSTYTIELTGTGSKLDAFLEAIDPALIIETVRTGASGIGRGE
RSLKV

Sequences:

>Translated_165_residues
MSTRHIISLLMENEAGALSRVAGLFSARAYNIESLTVAPTEDATLSRMTIVTVGSEDIIEQITKQLNKLVDVIKVMDLTE
GRHIERELMLVKVKATGLGREEMKRTADIFRGRIIDVTDSTYTIELTGTGSKLDAFLEAIDPALIIETVRTGASGIGRGE
RSLKV
>Mature_164_residues
STRHIISLLMENEAGALSRVAGLFSARAYNIESLTVAPTEDATLSRMTIVTVGSEDIIEQITKQLNKLVDVIKVMDLTEG
RHIERELMLVKVKATGLGREEMKRTADIFRGRIIDVTDSTYTIELTGTGSKLDAFLEAIDPALIIETVRTGASGIGRGER
SLKV

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=162, Percent_Identity=62.3456790123457, Blast_Score=207, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6319837, Length=204, Percent_Identity=28.921568627451, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18048; Mature: 17917

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRHIISLLMENEAGALSRVAGLFSARAYNIESLTVAPTEDATLSRMTIVTVGSEDIIE
CCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEECCHHHHH
QITKQLNKLVDVIKVMDLTEGRHIERELMLVKVKATGLGREEMKRTADIFRGRIIDVTDS
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCC
TYTIELTGTGSKLDAFLEAIDPALIIETVRTGASGIGRGERSLKV
EEEEEEECCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STRHIISLLMENEAGALSRVAGLFSARAYNIESLTVAPTEDATLSRMTIVTVGSEDIIE
CHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEECCHHHHH
QITKQLNKLVDVIKVMDLTEGRHIERELMLVKVKATGLGREEMKRTADIFRGRIIDVTDS
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCC
TYTIELTGTGSKLDAFLEAIDPALIIETVRTGASGIGRGERSLKV
EEEEEEECCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6308579; 1630901; 9278503; 1851954; 2198273 [H]