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The map label for this gene is trpE2 [H]

Identifier: 74317564

GI number: 74317564

Start: 1630134

End: 1631462

Strand: Reverse

Name: trpE2 [H]

Synonym: Tbd_1546

Alternate gene names: 74317564

Gene position: 1631462-1630134 (Counterclockwise)

Preceding gene: 74317565

Following gene: 74317563

Centisome position: 56.07

GC content: 68.17

Gene sequence:

>1329_bases
ATGTCCCCCTCTCGCTTCAATGCGCCCGAGATTCGTGAGTGGCCTCATACCCCTGACCTGATCCGCGTTCAGGCCGCTTG
GCCCGAGCGCTACCCCGGGCTGCTCGTCAGCAGCGGAGATGCGGGGTGGGACGTGCTCTTCGCGTTCCCGCGTGAGGTCG
TGGCCTTTTCCGCCCGTGACGGGGTCGACGCGCTCGCCGCGCACCCAGCGATGCAGATCCGGCCGCGCGCGTCTGACGGA
AGCGGCGACAGCTTGCCGTTCACCGGCGGCTGGCTCGCCGGCTTCGCTTACGAACTTGCCGGACTTTTCGAGACGAGCGT
CGGTCTTCCCGCGAATGACGATTTTCCCGTCGCATGGCTTGTGCGTATCCCTGCGGCGGTGCTCGTCAACCGCGGCAGCG
GACGCTGCGTCATCGTCGGCGAAGCCGGGCAGGGCGCGCTGGTCGAACTGCTCGCTGCGGATCTCGCGCGCGACCTGCCG
CCCCTTCCGACCTTGCCCGCGCTGACGGCGCTGGACGAGGACGATCCGGCGGCATTCCTCGGGGGCGTCTTGCGCATCCA
GGAATACATACGTGCAGGCGACGTATTCCAGGTCAATCTCTCGCGCGGCTGGCGCGCCGAATTTGCCATCGCGCCGACAC
CTGCGTCGCTGTTCGCGCAGCTCATGGCGCGCAACCCGGCGCCGTTTTCCGCCCTGTTGCAGATGGGCCCATGGGCGATC
GTCAGTTCCTCGCCCGAGCGGCTGGTGAGGCTGCGCGACGGCGTTCTCGAAACGCGGCCGATCGCCGGCACCCACCCGCG
CAGCGACGATGCCGACGAAGACGCCGCACTGCGCGCACGGCTCGAAGCCCATCCCAAGGAACGCGCCGAGCATGTGATGC
TGGTCGACCTCGAGCGCAACGACCTCGGGCGGGTGTGCGAGCCGGGCAGCGTCGAGGTGGCGGCACTGATGGAGCTTGCC
AGTTACCGCCACGTCCACCACATCGAATCGACCGTGCGTGGAAACCTGCGCCGGGGCCTGCGCGTGCTCGACGTGCTGCG
CGCGGTGTTTCCCGGCGGTACGATCACCGGCTGCCCGAAGGTCAGGACGATGCAGATCATCCACGAACTCGAGCGCACGC
CGCGCCGCAGTTATACCGGCAGCGTGGGCTACATCAACCTCGACGGCAGCTTCGATCTCAATATCCTGATCCGCAGCTTC
CTGCTGCAGGGCCGTTCACTGACTTTTCGCGCGGGCGCCGGCATCGTCGCCGACTCGGCCGCGCCGCGAGAACTCGAGGA
AACCCGTGCGAAAGCGCGGGGCCTCTTGCGCGCGCTGGAGGCCGCGTGA

Upstream 100 bases:

>100_bases
CGCGTTTGAGCCTGCCTCCCGGCGACGCGAAAACGTGACAGCAGATCGGGGCAGCCAGGCGCGGGCGCCACGTCGGCGCC
CCGCCTGACCCGGAAACCGA

Downstream 100 bases:

>100_bases
TCCTCGTCAACGGCGAGGCAAACGCCTGCGTCGACGCGCATGACCGCGGACTCGCGTACGGCGACGGCGTGTTCCGCACC
CTGCGCACCGAAGCCGGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSPSRFNAPEIREWPHTPDLIRVQAAWPERYPGLLVSSGDAGWDVLFAFPREVVAFSARDGVDALAAHPAMQIRPRASDG
SGDSLPFTGGWLAGFAYELAGLFETSVGLPANDDFPVAWLVRIPAAVLVNRGSGRCVIVGEAGQGALVELLAADLARDLP
PLPTLPALTALDEDDPAAFLGGVLRIQEYIRAGDVFQVNLSRGWRAEFAIAPTPASLFAQLMARNPAPFSALLQMGPWAI
VSSSPERLVRLRDGVLETRPIAGTHPRSDDADEDAALRARLEAHPKERAEHVMLVDLERNDLGRVCEPGSVEVAALMELA
SYRHVHHIESTVRGNLRRGLRVLDVLRAVFPGGTITGCPKVRTMQIIHELERTPRRSYTGSVGYINLDGSFDLNILIRSF
LLQGRSLTFRAGAGIVADSAAPRELEETRAKARGLLRALEAA

Sequences:

>Translated_442_residues
MSPSRFNAPEIREWPHTPDLIRVQAAWPERYPGLLVSSGDAGWDVLFAFPREVVAFSARDGVDALAAHPAMQIRPRASDG
SGDSLPFTGGWLAGFAYELAGLFETSVGLPANDDFPVAWLVRIPAAVLVNRGSGRCVIVGEAGQGALVELLAADLARDLP
PLPTLPALTALDEDDPAAFLGGVLRIQEYIRAGDVFQVNLSRGWRAEFAIAPTPASLFAQLMARNPAPFSALLQMGPWAI
VSSSPERLVRLRDGVLETRPIAGTHPRSDDADEDAALRARLEAHPKERAEHVMLVDLERNDLGRVCEPGSVEVAALMELA
SYRHVHHIESTVRGNLRRGLRVLDVLRAVFPGGTITGCPKVRTMQIIHELERTPRRSYTGSVGYINLDGSFDLNILIRSF
LLQGRSLTFRAGAGIVADSAAPRELEETRAKARGLLRALEAA
>Mature_441_residues
SPSRFNAPEIREWPHTPDLIRVQAAWPERYPGLLVSSGDAGWDVLFAFPREVVAFSARDGVDALAAHPAMQIRPRASDGS
GDSLPFTGGWLAGFAYELAGLFETSVGLPANDDFPVAWLVRIPAAVLVNRGSGRCVIVGEAGQGALVELLAADLARDLPP
LPTLPALTALDEDDPAAFLGGVLRIQEYIRAGDVFQVNLSRGWRAEFAIAPTPASLFAQLMARNPAPFSALLQMGPWAIV
SSSPERLVRLRDGVLETRPIAGTHPRSDDADEDAALRARLEAHPKERAEHVMLVDLERNDLGRVCEPGSVEVAALMELAS
YRHVHHIESTVRGNLRRGLRVLDVLRAVFPGGTITGCPKVRTMQIIHELERTPRRSYTGSVGYINLDGSFDLNILIRSFL
LQGRSLTFRAGAGIVADSAAPRELEETRAKARGLLRALEAA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=370, Percent_Identity=36.4864864864865, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1787518, Length=377, Percent_Identity=36.604774535809, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI87082077, Length=209, Percent_Identity=29.6650717703349, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786809, Length=224, Percent_Identity=25.4464285714286, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320935, Length=467, Percent_Identity=28.9079229122056, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6324361, Length=398, Percent_Identity=27.1356783919598, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR010118 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 47909; Mature: 47778

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSRFNAPEIREWPHTPDLIRVQAAWPERYPGLLVSSGDAGWDVLFAFPREVVAFSARD
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCHHHHHCHHHHHEECCCC
GVDALAAHPAMQIRPRASDGSGDSLPFTGGWLAGFAYELAGLFETSVGLPANDDFPVAWL
CCHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
VRIPAAVLVNRGSGRCVIVGEAGQGALVELLAADLARDLPPLPTLPALTALDEDDPAAFL
HHCCHHHEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHHH
GGVLRIQEYIRAGDVFQVNLSRGWRAEFAIAPTPASLFAQLMARNPAPFSALLQMGPWAI
HHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHCCCCCHHHHHHCCCEEE
VSSSPERLVRLRDGVLETRPIAGTHPRSDDADEDAALRARLEAHPKERAEHVMLVDLERN
ECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCEEEEEEECCC
DLGRVCEPGSVEVAALMELASYRHVHHIESTVRGNLRRGLRVLDVLRAVFPGGTITGCPK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VRTMQIIHELERTPRRSYTGSVGYINLDGSFDLNILIRSFLLQGRSLTFRAGAGIVADSA
HHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCEEECCC
APRELEETRAKARGLLRALEAA
CCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPSRFNAPEIREWPHTPDLIRVQAAWPERYPGLLVSSGDAGWDVLFAFPREVVAFSARD
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCHHHHHCHHHHHEECCCC
GVDALAAHPAMQIRPRASDGSGDSLPFTGGWLAGFAYELAGLFETSVGLPANDDFPVAWL
CCHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
VRIPAAVLVNRGSGRCVIVGEAGQGALVELLAADLARDLPPLPTLPALTALDEDDPAAFL
HHCCHHHEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHHH
GGVLRIQEYIRAGDVFQVNLSRGWRAEFAIAPTPASLFAQLMARNPAPFSALLQMGPWAI
HHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHCCCCCHHHHHHCCCEEE
VSSSPERLVRLRDGVLETRPIAGTHPRSDDADEDAALRARLEAHPKERAEHVMLVDLERN
ECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCEEEEEEECCC
DLGRVCEPGSVEVAALMELASYRHVHHIESTVRGNLRRGLRVLDVLRAVFPGGTITGCPK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VRTMQIIHELERTPRRSYTGSVGYINLDGSFDLNILIRSFLLQGRSLTFRAGAGIVADSA
HHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCEEECCC
APRELEETRAKARGLLRALEAA
CCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]