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The map label for this gene is pabC [H]

Identifier: 74317563

GI number: 74317563

Start: 1629331

End: 1630137

Strand: Reverse

Name: pabC [H]

Synonym: Tbd_1545

Alternate gene names: 74317563

Gene position: 1630137-1629331 (Counterclockwise)

Preceding gene: 74317564

Following gene: 74317562

Centisome position: 56.02

GC content: 69.89

Gene sequence:

>807_bases
GTGATCCTCGTCAACGGCGAGGCAAACGCCTGCGTCGACGCGCATGACCGCGGACTCGCGTACGGCGACGGCGTGTTCCG
CACCCTGCGCACCGAAGCCGGCGAGCCGCTGTGGTGGGCGGACCACTACGCGAAGCTGCGCGCGGACTGCGCGGCACTCG
CGCTCGATTGCCCGGCCGAGGACATGCTGCGCGAGGACATTCGCCGGATCGCCCTCGCCGGGAGCGGCGTCGTGAAGATC
ATCGTCACGCGCGGCAGCGGAACACGCGGCTATCTGCCGGCGCGAGGGGTCGCGACGCGGATCGTGATGTCGGCGCGTCT
GCCGCCGCATGCCGCCCCCGGCGCGCCCGTCGACGTGCGCGTCCGCTGGTGCAGCCTGCGGCTTTCGCGCCAGCCGCAGC
TCGCCGGCATCAAACATCTGAACCGCCTGGAAAACGTGCTCGCGCGCGCCGAGTGGGACGACCCGGACATCTTCGAGGGG
CTGCTCTGTGACGACGCCGGCGCGATCATCGGCGGTGTCATGACCAACGTCTTCTGGGTCAGCGCGGGCGAGCTGTTCAC
GCCGGATCTCGGCACATGCGGCGTCGCCGGTGTCGCGCGGGCGCGCGTGCTGCGGGCGGCAGCTCGGCGGGGTTTGCGCG
CCCGCGTCGAGCGGCTGCCTTCAGCCGCTATACTCGCTGCCGACGAAGTCATGATCTGCAACAGCCTGATCGGCGTGCGC
CGGGTCGCGCGCCTCGGCGACAAGACCTGGATGCCTGCTGGCTGGACCGACACTTTGAATGCTGCGCTCTATGAAGATCT
GGTTTAA

Upstream 100 bases:

>100_bases
TTCGCGCGGGCGCCGGCATCGTCGCCGACTCGGCCGCGCCGCGAGAACTCGAGGAAACCCGTGCGAAAGCGCGGGGCCTC
TTGCGCGCGCTGGAGGCCGC

Downstream 100 bases:

>100_bases
ACGCTTGCTCGGATTCGGCACGCTGGCGGCAGTGCTGCTCGCGGCGGGGCTTGCCTGGTATGCGACGCGGCCGCTCGTCA
TAACGCCCTTGCCGAAAACG

Product: aminodeoxychorismate lyase apoprotein

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MILVNGEANACVDAHDRGLAYGDGVFRTLRTEAGEPLWWADHYAKLRADCAALALDCPAEDMLREDIRRIALAGSGVVKI
IVTRGSGTRGYLPARGVATRIVMSARLPPHAAPGAPVDVRVRWCSLRLSRQPQLAGIKHLNRLENVLARAEWDDPDIFEG
LLCDDAGAIIGGVMTNVFWVSAGELFTPDLGTCGVAGVARARVLRAAARRGLRARVERLPSAAILAADEVMICNSLIGVR
RVARLGDKTWMPAGWTDTLNAALYEDLV

Sequences:

>Translated_268_residues
MILVNGEANACVDAHDRGLAYGDGVFRTLRTEAGEPLWWADHYAKLRADCAALALDCPAEDMLREDIRRIALAGSGVVKI
IVTRGSGTRGYLPARGVATRIVMSARLPPHAAPGAPVDVRVRWCSLRLSRQPQLAGIKHLNRLENVLARAEWDDPDIFEG
LLCDDAGAIIGGVMTNVFWVSAGELFTPDLGTCGVAGVARARVLRAAARRGLRARVERLPSAAILAADEVMICNSLIGVR
RVARLGDKTWMPAGWTDTLNAALYEDLV
>Mature_268_residues
MILVNGEANACVDAHDRGLAYGDGVFRTLRTEAGEPLWWADHYAKLRADCAALALDCPAEDMLREDIRRIALAGSGVVKI
IVTRGSGTRGYLPARGVATRIVMSARLPPHAAPGAPVDVRVRWCSLRLSRQPQLAGIKHLNRLENVLARAEWDDPDIFEG
LLCDDAGAIIGGVMTNVFWVSAGELFTPDLGTCGVAGVARARVLRAAARRGLRARVERLPSAAILAADEVMICNSLIGVR
RVARLGDKTWMPAGWTDTLNAALYEDLV

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=261, Percent_Identity=32.5670498084291, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 28915; Mature: 28915

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVNGEANACVDAHDRGLAYGDGVFRTLRTEAGEPLWWADHYAKLRADCAALALDCPAE
CEEECCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHEECCCHH
DMLREDIRRIALAGSGVVKIIVTRGSGTRGYLPARGVATRIVMSARLPPHAAPGAPVDVR
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEE
VRWCSLRLSRQPQLAGIKHLNRLENVLARAEWDDPDIFEGLLCDDAGAIIGGVMTNVFWV
EEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHE
SAGELFTPDLGTCGVAGVARARVLRAAARRGLRARVERLPSAAILAADEVMICNSLIGVR
ECCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHH
RVARLGDKTWMPAGWTDTLNAALYEDLV
HHHHHCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MILVNGEANACVDAHDRGLAYGDGVFRTLRTEAGEPLWWADHYAKLRADCAALALDCPAE
CEEECCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHEECCCHH
DMLREDIRRIALAGSGVVKIIVTRGSGTRGYLPARGVATRIVMSARLPPHAAPGAPVDVR
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEE
VRWCSLRLSRQPQLAGIKHLNRLENVLARAEWDDPDIFEGLLCDDAGAIIGGVMTNVFWV
EEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHE
SAGELFTPDLGTCGVAGVARARVLRAAARRGLRARVERLPSAAILAADEVMICNSLIGVR
ECCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHH
RVARLGDKTWMPAGWTDTLNAALYEDLV
HHHHHCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]