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The map label for this gene is narX [H]

Identifier: 74317418

GI number: 74317418

Start: 1479590

End: 1481524

Strand: Reverse

Name: narX [H]

Synonym: Tbd_1400

Alternate gene names: 74317418

Gene position: 1481524-1479590 (Counterclockwise)

Preceding gene: 74317429

Following gene: 74317417

Centisome position: 50.91

GC content: 66.98

Gene sequence:

>1935_bases
TTGGGGCCCTGTAGACAAGGCGCAAGGGAGAAAGCGGTGATCCGTTCGGGGCGGACCAAACTCGAGAACTCGCTGCTCAT
GCGGCTGGGCGGCATGTTTGTCGCGATCACCGTGCTCGCGGTCACCAGCATGTCGACCTCGTGGATGGTGGCCGAGACGA
TCCAGGGCAGCGGCGAGGCGATCAACCTTGCCGGCAGCCTGCGCATGCAGAGTTGGCGCATGGCTGCGATCTATCAGCGG
CTGCAGAGCGACGGCGCAACTGAAGACGCGGAGGATCTGGGGGAGGCGATCGCCCGCTTCGAGGCCGACCTCAAGGCGGC
ACCGATTCTCGCCGTGCTGCCGAGCGACGAGACCACGCCGCTCTGGCACGTCTACCGGCAGGTCGAAAACGACTGGCGCA
CCGTCGTCAAGCCCGGCTTGCAGGTCACGCCGGCCGCCGGGCGGCCCGCGCGCGGCAGCGTGCTCGACGACATTCCGGCG
TTCGTCGCCCACATCAACGACCTGGTCAAACAGATCGAGGACGCGGCCGAGGCCAAGATCCTGGTCATGCGCGTGATCCT
CGGAGCAGCCGTGATCGCGACGATGCTCGTCGTGGCGCTTGCCATCTATCTGGTCAACAACATTCTCGTCTACCCGCTGC
GCGGCCTGCTCGGGCTGGCCGACCAGATCGGCCAGGGCAATCTCGCGGTGCGCAACGATCTGACCGGCGAGGACGAGATC
GGGCGGCTCGGCCAGGCTTTCAACCACATGGCCGAAGACCTCTCGATGCTTTACCAGAACCTCGAGGCGCGGGTCGAGGA
GAAGACCGCGGAACTGACGATTGCCAACCGTTCGCTCGAACTGCTTTATCACTCGATCGCGCGGCTCTACAACGGCCCGA
TCGCCCCCCGTACCTACGAGATCCTGCTCAAGGACCTGGAGAACGTGCTCGGCCTCGGGCACGGCCTCGCGTGTCTGGTG
GAAGGCGACGGCGCGACGCGCGGGCGCGTGATCGCGAGCACCTTGCCGCCGCTGCCCGAGGGGGCCGACCCCTGCAGCGT
CATGAGCTGCGCCGAGTGTCTCGCGCGCCCGGCGCTCGCGGTCCACCCGCTCGGCGACGGCCGGCGCGTGCTGTCGCTGC
CGCTGAACGACACCGAGCAGCTGTATGGCGTGTTGCAACTCGAAATGCCGCCGGGCAAGGAACTGGTCCAGTGGCAAAGC
CAGTTGCTCGAAGCGCTGTCGCGCCACATCGGCATTGCGATCGGCACCGCGAGGCGCACCGAGCAGAGCCGTCGACTGTC
GCTGCTCGACGAGCGCGCCGCGCTCGCGCGCGACCTGCACGATTCGCTCGCGCAGTCGCTCGCCTACATGAAAATCCAGG
TCAGCCGGCTCAAGCCGCTGGTCGAAGGGTCGGGCGCCGGCAGCGAGGCCGGCGACGTGCTGGCCGAGTTGCGCGAAGGT
CTCAACAGCGCGTACCGCCAGCTACGCGAACTGCTGACGACCTTCCGCCTGCGAATCGAGGGTGAAGGCCTCGGCGCCGC
GCTGCAGACCACGGTGACCGAATTCTCCAACCGCGGCGGCATTCCGATCACGCTCGTCGTCCATCTGGCCGGGTGCAAGC
TCACGCCGAACGAGGAAATCCATGCGCTGCAAATCGTGCGCGAGGCGCTGTCCAACGTGCTCAATCACGCCCAGGCGCGC
CAGGCCGAGGTCAGTGTGAGCTGCAACAGCGACGGATCGGTGTCGGCCACCGTGACCGACGACGGCATCGGCATCCACGG
GACTGCACGCGCCCACCATTACGGGATGACGATCATGGAAGAGCGTGCGAAAAACCTCGGCGGCCGGCTCAGCGTCGAGA
ACCTTGCTGCACGGGGCACGCGCGTGGCCCTCCACTTCGTGCCGAGCACGCGGCGCGAGGACAACGGTACGATTCACCCC
ATTCAACCGAGCTGA

Upstream 100 bases:

>100_bases
TCGTTGCTGCTATTTTTGCGAGGCGGGCGCGTAGCCGGCGGCCTGACGAAGAAGAGGTATACCTATTTATCCGCGCGCCA
GACGCGCCGGTGTATTACGC

Downstream 100 bases:

>100_bases
AAGCCATGCCTACGACCGACCCCCAGACCATCCTGATCGTCGACGACCACCCGCTGTTTCGCAAGGGTGTGATCCAGCTC
ATCCAGGCGGCGCCGGAATT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 644; Mature: 643

Protein sequence:

>644_residues
MGPCRQGAREKAVIRSGRTKLENSLLMRLGGMFVAITVLAVTSMSTSWMVAETIQGSGEAINLAGSLRMQSWRMAAIYQR
LQSDGATEDAEDLGEAIARFEADLKAAPILAVLPSDETTPLWHVYRQVENDWRTVVKPGLQVTPAAGRPARGSVLDDIPA
FVAHINDLVKQIEDAAEAKILVMRVILGAAVIATMLVVALAIYLVNNILVYPLRGLLGLADQIGQGNLAVRNDLTGEDEI
GRLGQAFNHMAEDLSMLYQNLEARVEEKTAELTIANRSLELLYHSIARLYNGPIAPRTYEILLKDLENVLGLGHGLACLV
EGDGATRGRVIASTLPPLPEGADPCSVMSCAECLARPALAVHPLGDGRRVLSLPLNDTEQLYGVLQLEMPPGKELVQWQS
QLLEALSRHIGIAIGTARRTEQSRRLSLLDERAALARDLHDSLAQSLAYMKIQVSRLKPLVEGSGAGSEAGDVLAELREG
LNSAYRQLRELLTTFRLRIEGEGLGAALQTTVTEFSNRGGIPITLVVHLAGCKLTPNEEIHALQIVREALSNVLNHAQAR
QAEVSVSCNSDGSVSATVTDDGIGIHGTARAHHYGMTIMEERAKNLGGRLSVENLAARGTRVALHFVPSTRREDNGTIHP
IQPS

Sequences:

>Translated_644_residues
MGPCRQGAREKAVIRSGRTKLENSLLMRLGGMFVAITVLAVTSMSTSWMVAETIQGSGEAINLAGSLRMQSWRMAAIYQR
LQSDGATEDAEDLGEAIARFEADLKAAPILAVLPSDETTPLWHVYRQVENDWRTVVKPGLQVTPAAGRPARGSVLDDIPA
FVAHINDLVKQIEDAAEAKILVMRVILGAAVIATMLVVALAIYLVNNILVYPLRGLLGLADQIGQGNLAVRNDLTGEDEI
GRLGQAFNHMAEDLSMLYQNLEARVEEKTAELTIANRSLELLYHSIARLYNGPIAPRTYEILLKDLENVLGLGHGLACLV
EGDGATRGRVIASTLPPLPEGADPCSVMSCAECLARPALAVHPLGDGRRVLSLPLNDTEQLYGVLQLEMPPGKELVQWQS
QLLEALSRHIGIAIGTARRTEQSRRLSLLDERAALARDLHDSLAQSLAYMKIQVSRLKPLVEGSGAGSEAGDVLAELREG
LNSAYRQLRELLTTFRLRIEGEGLGAALQTTVTEFSNRGGIPITLVVHLAGCKLTPNEEIHALQIVREALSNVLNHAQAR
QAEVSVSCNSDGSVSATVTDDGIGIHGTARAHHYGMTIMEERAKNLGGRLSVENLAARGTRVALHFVPSTRREDNGTIHP
IQPS
>Mature_643_residues
GPCRQGAREKAVIRSGRTKLENSLLMRLGGMFVAITVLAVTSMSTSWMVAETIQGSGEAINLAGSLRMQSWRMAAIYQRL
QSDGATEDAEDLGEAIARFEADLKAAPILAVLPSDETTPLWHVYRQVENDWRTVVKPGLQVTPAAGRPARGSVLDDIPAF
VAHINDLVKQIEDAAEAKILVMRVILGAAVIATMLVVALAIYLVNNILVYPLRGLLGLADQIGQGNLAVRNDLTGEDEIG
RLGQAFNHMAEDLSMLYQNLEARVEEKTAELTIANRSLELLYHSIARLYNGPIAPRTYEILLKDLENVLGLGHGLACLVE
GDGATRGRVIASTLPPLPEGADPCSVMSCAECLARPALAVHPLGDGRRVLSLPLNDTEQLYGVLQLEMPPGKELVQWQSQ
LLEALSRHIGIAIGTARRTEQSRRLSLLDERAALARDLHDSLAQSLAYMKIQVSRLKPLVEGSGAGSEAGDVLAELREGL
NSAYRQLRELLTTFRLRIEGEGLGAALQTTVTEFSNRGGIPITLVVHLAGCKLTPNEEIHALQIVREALSNVLNHAQARQ
AEVSVSCNSDGSVSATVTDDGIGIHGTARAHHYGMTIMEERAKNLGGRLSVENLAARGTRVALHFVPSTRREDNGTIHPI
QPS

Specific function: Acts as a sensor for nitrate/nitrite and transduces signal of nitrate availability to the narL protein and of both nitrate/nitrite to the narP protein. NarX probably activates narL and narP by phosphorylation in the presence of nitrate. NarX also plays a

COG id: COG3850

COG function: function code T; Signal transduction histidine kinase, nitrate/nitrite-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=617, Percent_Identity=33.54943273906, Blast_Score=268, Evalue=9e-73,
Organism=Escherichia coli, GI1788812, Length=609, Percent_Identity=30.5418719211823, Blast_Score=216, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR016380
- InterPro:   IPR003661
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69553; Mature: 69422

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPCRQGAREKAVIRSGRTKLENSLLMRLGGMFVAITVLAVTSMSTSWMVAETIQGSGEA
CCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCE
INLAGSLRMQSWRMAAIYQRLQSDGATEDAEDLGEAIARFEADLKAAPILAVLPSDETTP
EEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
LWHVYRQVENDWRTVVKPGLQVTPAAGRPARGSVLDDIPAFVAHINDLVKQIEDAAEAKI
HHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVMRVILGAAVIATMLVVALAIYLVNNILVYPLRGLLGLADQIGQGNLAVRNDLTGEDEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHH
GRLGQAFNHMAEDLSMLYQNLEARVEEKTAELTIANRSLELLYHSIARLYNGPIAPRTYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHCCCCCCHHHH
ILLKDLENVLGLGHGLACLVEGDGATRGRVIASTLPPLPEGADPCSVMSCAECLARPALA
HHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEE
VHPLGDGRRVLSLPLNDTEQLYGVLQLEMPPGKELVQWQSQLLEALSRHIGIAIGTARRT
EEECCCCCEEEEECCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCEEEECHHHH
EQSRRLSLLDERAALARDLHDSLAQSLAYMKIQVSRLKPLVEGSGAGSEAGDVLAELREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHH
LNSAYRQLRELLTTFRLRIEGEGLGAALQTTVTEFSNRGGIPITLVVHLAGCKLTPNEEI
HHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHH
HALQIVREALSNVLNHAQARQAEVSVSCNSDGSVSATVTDDGIGIHGTARAHHYGMTIME
HHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
ERAKNLGGRLSVENLAARGTRVALHFVPSTRREDNGTIHPIQPS
HHHHCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEECCCCC
>Mature Secondary Structure 
GPCRQGAREKAVIRSGRTKLENSLLMRLGGMFVAITVLAVTSMSTSWMVAETIQGSGEA
CCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCE
INLAGSLRMQSWRMAAIYQRLQSDGATEDAEDLGEAIARFEADLKAAPILAVLPSDETTP
EEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
LWHVYRQVENDWRTVVKPGLQVTPAAGRPARGSVLDDIPAFVAHINDLVKQIEDAAEAKI
HHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVMRVILGAAVIATMLVVALAIYLVNNILVYPLRGLLGLADQIGQGNLAVRNDLTGEDEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHH
GRLGQAFNHMAEDLSMLYQNLEARVEEKTAELTIANRSLELLYHSIARLYNGPIAPRTYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHCCCCCCHHHH
ILLKDLENVLGLGHGLACLVEGDGATRGRVIASTLPPLPEGADPCSVMSCAECLARPALA
HHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEE
VHPLGDGRRVLSLPLNDTEQLYGVLQLEMPPGKELVQWQSQLLEALSRHIGIAIGTARRT
EEECCCCCEEEEECCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCEEEECHHHH
EQSRRLSLLDERAALARDLHDSLAQSLAYMKIQVSRLKPLVEGSGAGSEAGDVLAELREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHH
LNSAYRQLRELLTTFRLRIEGEGLGAALQTTVTEFSNRGGIPITLVVHLAGCKLTPNEEI
HHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHH
HALQIVREALSNVLNHAQARQAEVSVSCNSDGSVSATVTDDGIGIHGTARAHHYGMTIME
HHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
ERAKNLGGRLSVENLAARGTRVALHFVPSTRREDNGTIHPIQPS
HHHHCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]