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The map label for this gene is narL [H]

Identifier: 74317417

GI number: 74317417

Start: 1478925

End: 1479584

Strand: Reverse

Name: narL [H]

Synonym: Tbd_1399

Alternate gene names: 74317417

Gene position: 1479584-1478925 (Counterclockwise)

Preceding gene: 74317418

Following gene: 74317416

Centisome position: 50.85

GC content: 64.55

Gene sequence:

>660_bases
ATGCCTACGACCGACCCCCAGACCATCCTGATCGTCGACGACCACCCGCTGTTTCGCAAGGGTGTGATCCAGCTCATCCA
GGCGGCGCCGGAATTCCGCTTCGTCGGCGAAGCGGCGAGCGGCGGGGAAGGCCTTACGCTCGCGCACCGCCTGCACCCCG
ACATGATCCTGCTCGATCTCAACATGAAGGACATGAACGGCGTCGAGGTGCTCAAGGCCATCAAGGACGAGGGGCTGGAT
TCACGGGTGATCATGCTGACCGTGTCGGACCAGGCGGAAGACCTGATCGCCGCGTTGCAGGCAGGCGCCGACGGCTACCT
GCTCAAGGACATGGAGCCCGAAGACCTGATGCAGCAACTGGCCGAGGCAGCGCGCGGCAAGATCACGATCAGCGAAGGCC
TGACGCAGTTGCTCGTCTCGTCCCTGCGAGAGAAGACGCGGCCGACGAGCCTCGCCGACGCAGGACTCACCGAGCAGGAA
AACCGCATCCTCGACCACCTCGTCGACGGCAAGAGCAACAAGCTCATCGCCCGCGACATGGGCATCGCCGAGGGCACCGT
GAAAGTGCACGTCAAGCATCTCCTCAAGAAACTCAACCTCCGGTCGCGGGTCGAGGCGGCGGTGTGGGCGGATCGCTGTC
GCCGGCAGGCGAAACCCTGA

Upstream 100 bases:

>100_bases
ACCTTGCTGCACGGGGCACGCGCGTGGCCCTCCACTTCGTGCCGAGCACGCGGCGCGAGGACAACGGTACGATTCACCCC
ATTCAACCGAGCTGAAAGCC

Downstream 100 bases:

>100_bases
AGCGGGTTGCGCGCATTCACCCGACGGGAGCGCGGTCGCCCCGCCGGACCAATGATGTATCGTTTATGCAACTTTGCTGA
CCGTGCAAAAGAGGGGATTA

Product: transcriptional regulator NarL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MPTTDPQTILIVDDHPLFRKGVIQLIQAAPEFRFVGEAASGGEGLTLAHRLHPDMILLDLNMKDMNGVEVLKAIKDEGLD
SRVIMLTVSDQAEDLIAALQAGADGYLLKDMEPEDLMQQLAEAARGKITISEGLTQLLVSSLREKTRPTSLADAGLTEQE
NRILDHLVDGKSNKLIARDMGIAEGTVKVHVKHLLKKLNLRSRVEAAVWADRCRRQAKP

Sequences:

>Translated_219_residues
MPTTDPQTILIVDDHPLFRKGVIQLIQAAPEFRFVGEAASGGEGLTLAHRLHPDMILLDLNMKDMNGVEVLKAIKDEGLD
SRVIMLTVSDQAEDLIAALQAGADGYLLKDMEPEDLMQQLAEAARGKITISEGLTQLLVSSLREKTRPTSLADAGLTEQE
NRILDHLVDGKSNKLIARDMGIAEGTVKVHVKHLLKKLNLRSRVEAAVWADRCRRQAKP
>Mature_218_residues
PTTDPQTILIVDDHPLFRKGVIQLIQAAPEFRFVGEAASGGEGLTLAHRLHPDMILLDLNMKDMNGVEVLKAIKDEGLDS
RVIMLTVSDQAEDLIAALQAGADGYLLKDMEPEDLMQQLAEAARGKITISEGLTQLLVSSLREKTRPTSLADAGLTEQEN
RILDHLVDGKSNKLIARDMGIAEGTVKVHVKHLLKKLNLRSRVEAAVWADRCRRQAKP

Specific function: This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787473, Length=215, Percent_Identity=52.093023255814, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1788521, Length=211, Percent_Identity=45.9715639810426, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1788222, Length=198, Percent_Identity=27.7777777777778, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=30, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1788712, Length=203, Percent_Identity=23.6453201970443, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786747, Length=213, Percent_Identity=30.0469483568075, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87082052, Length=113, Percent_Identity=33.6283185840708, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24085; Mature: 23954

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTTDPQTILIVDDHPLFRKGVIQLIQAAPEFRFVGEAASGGEGLTLAHRLHPDMILLDL
CCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEHEECCCCEEEEEC
NMKDMNGVEVLKAIKDEGLDSRVIMLTVSDQAEDLIAALQAGADGYLLKDMEPEDLMQQL
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHCCCCCEEECCCCHHHHHHHH
AEAARGKITISEGLTQLLVSSLREKTRPTSLADAGLTEQENRILDHLVDGKSNKLIARDM
HHHHCCCEEHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHCCCCCCEEECCC
GIAEGTVKVHVKHLLKKLNLRSRVEAAVWADRCRRQAKP
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PTTDPQTILIVDDHPLFRKGVIQLIQAAPEFRFVGEAASGGEGLTLAHRLHPDMILLDL
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEHEECCCCEEEEEC
NMKDMNGVEVLKAIKDEGLDSRVIMLTVSDQAEDLIAALQAGADGYLLKDMEPEDLMQQL
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHCCCCCEEECCCCHHHHHHHH
AEAARGKITISEGLTQLLVSSLREKTRPTSLADAGLTEQENRILDHLVDGKSNKLIARDM
HHHHCCCEEHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHCCCCCCEEECCC
GIAEGTVKVHVKHLLKKLNLRSRVEAAVWADRCRRQAKP
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]