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The map label for this gene is yciR [C]

Identifier: 74317429

GI number: 74317429

Start: 1496699

End: 1498669

Strand: Reverse

Name: yciR [C]

Synonym: Tbd_1411

Alternate gene names: 74317429

Gene position: 1498669-1496699 (Counterclockwise)

Preceding gene: 74317430

Following gene: 74317418

Centisome position: 51.5

GC content: 66.57

Gene sequence:

>1971_bases
ATGACCCACGACGTTCACCGGGGGGGACTTCTCGACCATCAGGCGCTGGCGTGGGTCGTGCTCGCCGTTGCGCTGCTGTT
CACGTTCGCGACCTGGCAGCATTTCGACGCCGCGCGTGCCCACCACGATCAGGACCGTTTCATGCGCGCCGCGGAAAAGC
AGCGGAACATCCTGACCAATCGCATCCACGACTACGAGCAGGTTCTGCGTGGCGGGGCCGCACTGTTTGCGGCAGGTGGC
GTGCCCAGCCGCAGCGAGTGGCGGACCTATGTCGACGAGCTCGACCTCGAGCGCTCGCTGCCAGGCATTCTGGCGACCGG
TTTCGCGCTCATGGTGCCGCCCGAAGCCAAGGCGGCGCACGAGCAGTCCGTCCGCGCGGAGGGGTTTCCGGATTACGCGA
TCGTTCCGCCCGGCGAGCGCGCCATGCTGAGCAGCATCGTCTACATCGAGCCGTTCAGCGGGCGCAACCTGCGCGCCTTC
GGTTACGACATGTATTCCGAGCCGACGCGCCGCGAAGCGATGGACCGCGCGCGCGACAGCGGCCAGCCCGCGTTGTCGCG
CAAGGTCACGCTCGTGCAGGAAACCCGCACGGGCGTGCAGCCCGGCTTTCTGATCTACTTCCCTGTTTACCGCAGCGGCC
AGCCGATCGACACTGTAGCGGCCCGGCGCGCGGCCCTGCTCGGCTTCGTATACAGTCCATTCCGCGCCTACGATCTGCTC
GACGGGGTGTTTGACACCCCCACCCAAATCCTCGAGATCGAATTGTTCGACGGCGGCGCATCGCCCGAGAACCTGCTTTA
CGCCACCGAAGGCGCGACGCGCGACGCGCGGCTGATGACCGAGATGAAGCTCGAGGTCGGTGGAAACATCTGGGTCGCGC
GCTTCCGCAGCAGCGAACGCTACGAGTCGCTCGAAGGAATCATGCAGCCGACGATGGTCCTCGTCGGCGGGGTCGCGCTC
GACTTTCTGTTGTTTTCCGTGCTCTACATGAATGCCCGCCACCGGCGCAAGATGCGGATTTCAGCGGCCAAGCTCGCTCA
AAGCCTCGACAGCTACAAGGCGCTCGTCGAAAACATCCCGGGCGCGGTGTTCCGCTGCGAGGTCGGATCGCCCGCACCGC
TGAGACGGCTGAGCAGCGGCATTGCGCCGCTGACCGGCGAGGCGTCGGAGCGTTTCCTTTCTGGAGACGTGTCCTACCAG
GAACTGATCCATCCCGACGACCGGGCCGCGGTCGCCGAGGCGGTTGCCGAAGCCGTCGCCAAGCGAAGCACCTACAACGT
CGAGTACCGGATCAAGGCCCGCGACGGCTTCACGCGTTGGGTCAGCGAACGCGGTCAGGTCAGCTCGGATGCCGCGGGAC
GCGCGCAGTGGCTCGACGGAGTCGTCCTCGACATCACCGAACGCAAGGCCGCCGAGATCATGATCCGCGACCTCGCGTTC
AACGACACCCTGACCGGACTGCCCAACCGGCGTCTGCTCCTCGACCGCCTCGAACAGCAGCTTGCCGCGAGCGGCCGCGC
CGGTCGCCACGGCGCGCTGCTGTTCATCGACATGGACAACTTCAAGACCGTCAACGATACGCTCGGGCACGCGGCCGGCG
ACCAGGTTCTCGTCGAGGTCGCGGCGCGCCTGCTTGCGAGCGTCCGGGAAAGCGATACCGTCGCCCGTCTCGGCGGCGAT
GAATTCGTCGTGGTCATCGGCAATCTCGGCAATACCGCCGAGGCGGCCAAGGCCGAAGCCGCCGAACTCGGTGACAAGAT
TCTGCTCAAGCTGTCGCAGCCCTACCGGCTCGGCGCGCACCTGCACAACAGCACGCCGAGCATCGGCATCACGACCTTCT
GCGGCCACCACGTCAGCGCCGGCCAACTCCTGCGCCGCGCCGATCAGGCGATGTACCGCGCCAAGTCGGCGGGCCGCCAT
CAGGTCAAGTTCTACGAGGAAGACACCGCGCCCGCTGTGCGCGTCGCCTGA

Upstream 100 bases:

>100_bases
CACCGGCTGCTCTGCCCCGTACGCGCCGGCCCGATACGAGCGACGTGCATGCCCAAGCGGGTTTTCTGCTTCGCATCGCG
GCTGCGCTGGGCGCGCAGCC

Downstream 100 bases:

>100_bases
GCGTCAGGGCGCGAGGGGCGCGCCGGGACCTACCCGGATCACCGTACCTTCGCGGCGCGGATCGGCGGCGCCGTACTGCG
CGCCACTGGTCAGGTCGACG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 655

Protein sequence:

>656_residues
MTHDVHRGGLLDHQALAWVVLAVALLFTFATWQHFDAARAHHDQDRFMRAAEKQRNILTNRIHDYEQVLRGGAALFAAGG
VPSRSEWRTYVDELDLERSLPGILATGFALMVPPEAKAAHEQSVRAEGFPDYAIVPPGERAMLSSIVYIEPFSGRNLRAF
GYDMYSEPTRREAMDRARDSGQPALSRKVTLVQETRTGVQPGFLIYFPVYRSGQPIDTVAARRAALLGFVYSPFRAYDLL
DGVFDTPTQILEIELFDGGASPENLLYATEGATRDARLMTEMKLEVGGNIWVARFRSSERYESLEGIMQPTMVLVGGVAL
DFLLFSVLYMNARHRRKMRISAAKLAQSLDSYKALVENIPGAVFRCEVGSPAPLRRLSSGIAPLTGEASERFLSGDVSYQ
ELIHPDDRAAVAEAVAEAVAKRSTYNVEYRIKARDGFTRWVSERGQVSSDAAGRAQWLDGVVLDITERKAAEIMIRDLAF
NDTLTGLPNRRLLLDRLEQQLAASGRAGRHGALLFIDMDNFKTVNDTLGHAAGDQVLVEVAARLLASVRESDTVARLGGD
EFVVVIGNLGNTAEAAKAEAAELGDKILLKLSQPYRLGAHLHNSTPSIGITTFCGHHVSAGQLLRRADQAMYRAKSAGRH
QVKFYEEDTAPAVRVA

Sequences:

>Translated_656_residues
MTHDVHRGGLLDHQALAWVVLAVALLFTFATWQHFDAARAHHDQDRFMRAAEKQRNILTNRIHDYEQVLRGGAALFAAGG
VPSRSEWRTYVDELDLERSLPGILATGFALMVPPEAKAAHEQSVRAEGFPDYAIVPPGERAMLSSIVYIEPFSGRNLRAF
GYDMYSEPTRREAMDRARDSGQPALSRKVTLVQETRTGVQPGFLIYFPVYRSGQPIDTVAARRAALLGFVYSPFRAYDLL
DGVFDTPTQILEIELFDGGASPENLLYATEGATRDARLMTEMKLEVGGNIWVARFRSSERYESLEGIMQPTMVLVGGVAL
DFLLFSVLYMNARHRRKMRISAAKLAQSLDSYKALVENIPGAVFRCEVGSPAPLRRLSSGIAPLTGEASERFLSGDVSYQ
ELIHPDDRAAVAEAVAEAVAKRSTYNVEYRIKARDGFTRWVSERGQVSSDAAGRAQWLDGVVLDITERKAAEIMIRDLAF
NDTLTGLPNRRLLLDRLEQQLAASGRAGRHGALLFIDMDNFKTVNDTLGHAAGDQVLVEVAARLLASVRESDTVARLGGD
EFVVVIGNLGNTAEAAKAEAAELGDKILLKLSQPYRLGAHLHNSTPSIGITTFCGHHVSAGQLLRRADQAMYRAKSAGRH
QVKFYEEDTAPAVRVA
>Mature_655_residues
THDVHRGGLLDHQALAWVVLAVALLFTFATWQHFDAARAHHDQDRFMRAAEKQRNILTNRIHDYEQVLRGGAALFAAGGV
PSRSEWRTYVDELDLERSLPGILATGFALMVPPEAKAAHEQSVRAEGFPDYAIVPPGERAMLSSIVYIEPFSGRNLRAFG
YDMYSEPTRREAMDRARDSGQPALSRKVTLVQETRTGVQPGFLIYFPVYRSGQPIDTVAARRAALLGFVYSPFRAYDLLD
GVFDTPTQILEIELFDGGASPENLLYATEGATRDARLMTEMKLEVGGNIWVARFRSSERYESLEGIMQPTMVLVGGVALD
FLLFSVLYMNARHRRKMRISAAKLAQSLDSYKALVENIPGAVFRCEVGSPAPLRRLSSGIAPLTGEASERFLSGDVSYQE
LIHPDDRAAVAEAVAEAVAKRSTYNVEYRIKARDGFTRWVSERGQVSSDAAGRAQWLDGVVLDITERKAAEIMIRDLAFN
DTLTGLPNRRLLLDRLEQQLAASGRAGRHGALLFIDMDNFKTVNDTLGHAAGDQVLVEVAARLLASVRESDTVARLGGDE
FVVVIGNLGNTAEAAKAEAAELGDKILLKLSQPYRLGAHLHNSTPSIGITTFCGHHVSAGQLLRRADQAMYRAKSAGRHQ
VKFYEEDTAPAVRVA

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=225, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1788381, Length=199, Percent_Identity=35.678391959799, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI145693134, Length=167, Percent_Identity=35.3293413173653, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081977, Length=210, Percent_Identity=31.9047619047619, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI87081881, Length=182, Percent_Identity=35.1648351648352, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786584, Length=163, Percent_Identity=32.5153374233129, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788956, Length=162, Percent_Identity=38.8888888888889, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787262, Length=219, Percent_Identity=29.6803652968037, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082007, Length=174, Percent_Identity=35.632183908046, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787816, Length=186, Percent_Identity=33.8709677419355, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87081974, Length=87, Percent_Identity=42.5287356321839, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788085, Length=207, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787802, Length=164, Percent_Identity=28.6585365853659, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 72285; Mature: 72154

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50839 CHASE ; PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDVHRGGLLDHQALAWVVLAVALLFTFATWQHFDAARAHHDQDRFMRAAEKQRNILTN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RIHDYEQVLRGGAALFAAGGVPSRSEWRTYVDELDLERSLPGILATGFALMVPPEAKAAH
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCHHHHH
EQSVRAEGFPDYAIVPPGERAMLSSIVYIEPFSGRNLRAFGYDMYSEPTRREAMDRARDS
HHHHCCCCCCCEEEECCCHHHHHHHEEEEECCCCCCEEEECCCHHCCCHHHHHHHHHHCC
GQPALSRKVTLVQETRTGVQPGFLIYFPVYRSGQPIDTVAARRAALLGFVYSPFRAYDLL
CCCHHHHHEEEEHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DGVFDTPTQILEIELFDGGASPENLLYATEGATRDARLMTEMKLEVGGNIWVARFRSSER
HHHHCCCCEEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCHH
YESLEGIMQPTMVLVGGVALDFLLFSVLYMNARHRRKMRISAAKLAQSLDSYKALVENIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAVFRCEVGSPAPLRRLSSGIAPLTGEASERFLSGDVSYQELIHPDDRAAVAEAVAEAVA
CCEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHH
KRSTYNVEYRIKARDGFTRWVSERGQVSSDAAGRAQWLDGVVLDITERKAAEIMIRDLAF
HCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHCCEEEEECHHHHHHHHHHHHHC
NDTLTGLPNRRLLLDRLEQQLAASGRAGRHGALLFIDMDNFKTVNDTLGHAAGDQVLVEV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHCCCCCHHHHHHH
AARLLASVRESDTVARLGGDEFVVVIGNLGNTAEAAKAEAAELGDKILLKLSQPYRLGAH
HHHHHHHHHCCCCCEEECCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHCCCE
LHNSTPSIGITTFCGHHVSAGQLLRRADQAMYRAKSAGRHQVKFYEEDTAPAVRVA
ECCCCCCCCEEHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECC
>Mature Secondary Structure 
THDVHRGGLLDHQALAWVVLAVALLFTFATWQHFDAARAHHDQDRFMRAAEKQRNILTN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RIHDYEQVLRGGAALFAAGGVPSRSEWRTYVDELDLERSLPGILATGFALMVPPEAKAAH
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCHHHHH
EQSVRAEGFPDYAIVPPGERAMLSSIVYIEPFSGRNLRAFGYDMYSEPTRREAMDRARDS
HHHHCCCCCCCEEEECCCHHHHHHHEEEEECCCCCCEEEECCCHHCCCHHHHHHHHHHCC
GQPALSRKVTLVQETRTGVQPGFLIYFPVYRSGQPIDTVAARRAALLGFVYSPFRAYDLL
CCCHHHHHEEEEHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DGVFDTPTQILEIELFDGGASPENLLYATEGATRDARLMTEMKLEVGGNIWVARFRSSER
HHHHCCCCEEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCHH
YESLEGIMQPTMVLVGGVALDFLLFSVLYMNARHRRKMRISAAKLAQSLDSYKALVENIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAVFRCEVGSPAPLRRLSSGIAPLTGEASERFLSGDVSYQELIHPDDRAAVAEAVAEAVA
CCEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHH
KRSTYNVEYRIKARDGFTRWVSERGQVSSDAAGRAQWLDGVVLDITERKAAEIMIRDLAF
HCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHCCEEEEECHHHHHHHHHHHHHC
NDTLTGLPNRRLLLDRLEQQLAASGRAGRHGALLFIDMDNFKTVNDTLGHAAGDQVLVEV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHCCCCCHHHHHHH
AARLLASVRESDTVARLGGDEFVVVIGNLGNTAEAAKAEAAELGDKILLKLSQPYRLGAH
HHHHHHHHHCCCCCEEECCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHCCCE
LHNSTPSIGITTFCGHHVSAGQLLRRADQAMYRAKSAGRHQVKFYEEDTAPAVRVA
ECCCCCCCCEEHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]