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The map label for this gene is nuoG [H]

Identifier: 74317166

GI number: 74317166

Start: 1201592

End: 1203946

Strand: Direct

Name: nuoG [H]

Synonym: Tbd_1148

Alternate gene names: 74317166

Gene position: 1201592-1203946 (Clockwise)

Preceding gene: 74317165

Following gene: 74317167

Centisome position: 41.29

GC content: 66.71

Gene sequence:

>2355_bases
ATGGCTACCCTGAATATCGAAATCGATGGGCGCGCGCTGCAGGTCGAAAGCGGCGACACCATCATGGACGCCGCGAACCA
GGCGGGTATCACGATTCCGCATTTCTGCTATCACAAGAAGCTCTCGATCGCCGCGAACTGTCGCATGTGCCTGGTTCAGG
TCGAGAAGGCGCCGAAGCCGCTGCCGGCCTGCGCCACGCCCGTCACCGAGGGCATGAAGGTCCACACCCGCTCGGAATAT
GCGATCAACGCACAAAAAGGCGTGATGGAATTCCTGTTGATCAATCACCCGCTCGACTGCCCGATTTGCGACCAGGGCGG
CGAATGCACGCTGCAGGATCTGGCGGTCGGCTACGGCGGTTCGTCCTCGCGCTACCAGGAGATCAAACGCGTCGTGCGCG
AGAAGAATCTCGGGCCGCTCATCGCGACCGACATGACGCGCTGCATCCACTGCAGCCGCTGCGTGCGTTTCGGCCAGGAA
ATCGCCGGGATGATGGAACTCGGCATGCCTGGGCGCGGCGAGCACACGGAAGTTATGCCCTTCCTCGAAGGCCAGGTCGC
GTCGGAATTGTCGGGCAACGTCATCGACCTCTGCCCGGTGGGCGCGTTGACCAGCAAGCCGTTCCGCTACACCGCCCGGC
CCTGGGAGTTGTCGCGCCGCCCGTCGATAAGCCCGCACGACAGCCTCGGCTCGAATCTCGAGGTGCACGTCAAGAACAAC
AAGGTCATGCGCGTGGTGCCGCGCGAGAACGAGGACGTCAACGAATGCTGGCTCGCCGACCGCGACCGCTTTTCGTACGA
GGGACTCAACACGGCCGAGCGCCTGACCTGGCCGATGATCAAGCAGGACGGCCAGTGGATCGAGACCGACTGGCGGACCG
CGCTGCAATACGTCGCCGACAGGCTGAAGGCCATTCCGCCCGAGCAGATCGGTGCGCTGTCGACGCCGCACCGGCCGGCG
GAAGAACTGTTTCTGCTGCAGAAGCTCATGCGCGGCATGGGCAGCGGCAACGTCGACCACCGTCTGCGGCAGTCGGATTT
CGCGCTCGACGCCAAGGCGCAGGGCGGCTTCTGGCTCGGCATGCCCGTGACCTACATGTCGCGCCTCAACCGCATGCTCG
TCGTCGGCTCCAACCTGCGCAAGGATCATCCGCTGATGGCCCACCGCATACGCGAGGCGGTGCGGTGGTACGGCGAACTT
AACCTGATCAATGCTGCGGACGACGAATTCCTCGGCAAGGTCCACGCCAAACGCATCGTCGCACCGTCGCAGCTCGCCGG
CGCGCTCGCCGGCGTGTGCGTCGCGCTGGCCGAACTGAAAAATCAGGCGGTGCCGAAGATCGCGGCGCACGGAGTCGTCG
ACGAGGTGGCGCGCAAGATGGCCGCGAGCCTCGCCGGCGGCGAGACCCGCGCGGTCTTCCTCGGCAACATGGCGCAGCAT
CATCCGGCTTACTCGCAGATTCACGCGCTCGCGCAGGAAGTCGCGGCGCTTGCGGGGGCGAGTTTCGGCGTCCTCGGCGA
GGCGGCCAACAGCGTCGGGGCCGTCGCCGTCGGCGCGATCCCGGGGCGCGGCCCGCTCGGCCAGCCGGCAGTCGCCGGAC
TCAATGCCCAGGAAATGCTCGCGAAGCCCTTGCGCGCGTATCTGCTCCTCGGCGTCGAGGCCGAACTCGACACCTACGAC
CCCGTGGCCGCCATGGCGAGCATCGACGCCGCCGACTTCGTCGTCGTGATGTCGCCGTACAAGGGCAAATCGCTCGACTA
CGCGGACGTGTTGCTGCCGATCGCACCGTGGACCGAGACCTCGGGCACCTTCATCAACACCGAGGGCCGCGTGCAGAGCT
TCGCCGCAGTCGTGAAGCCGCTCGCCGAGACGCGGCCGGCGTGGAAGGTGTTGCGCGTGCTGGGCAACCTGCTGGGGCTC
GCGGGTTTTGAGCACGCCGATTCGAAGGAGGTCCTGCGCGATGCCTTGGGTGAGACACCCATCGGCTCGGTCCAGGCCTT
CCTCAATAACGCTGTCAGTGACGTGGACATGCAGCCCGCTCCCGCGGGCGAGCATCTCGAACGCGTCGCCGAAGTGCCGA
TCTACCAGACCGACGCCGTCGTGCGCCGCGCGCCGTCCCTGCAACGCACGCAGGACGGCGCACTGCCGGTCGCGCGCATG
CACAGCCGGCTCATCGCCCGCCTCGGACTCGAGGAAGACGGGCGGGTCTCGGTGCGCCAGACCGCGTCGGCGCTGACACT
GAAGGTGCAGCGCGACGACCTGCTGCCTGACAACTGCGTGCGTATTCCGAGCGGCCATCCGTTGACGGCCGGGCTCGGCC
CGATGTTTGGGCCGATCACCGCGGAGCCGGTCTGA

Upstream 100 bases:

>100_bases
GCGGCGGCCATGCCGGTGCAAAGCTTCCTCAAACATTTCGGCCACGAGTTCGAGCATCACATCGAACACAAGCGCTGCAT
GGTCTGACGGTACGACAACG

Downstream 100 bases:

>100_bases
TGGAGGCGGGTATCGTGGAGGCCGCGGGAATGGATTGGGAGGCGTTCCAGACCGTCGCATGGACGCTGGTCAAGATCATG
GCGCTGGTCGTGCCGCTGAT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 784; Mature: 783

Protein sequence:

>784_residues
MATLNIEIDGRALQVESGDTIMDAANQAGITIPHFCYHKKLSIAANCRMCLVQVEKAPKPLPACATPVTEGMKVHTRSEY
AINAQKGVMEFLLINHPLDCPICDQGGECTLQDLAVGYGGSSSRYQEIKRVVREKNLGPLIATDMTRCIHCSRCVRFGQE
IAGMMELGMPGRGEHTEVMPFLEGQVASELSGNVIDLCPVGALTSKPFRYTARPWELSRRPSISPHDSLGSNLEVHVKNN
KVMRVVPRENEDVNECWLADRDRFSYEGLNTAERLTWPMIKQDGQWIETDWRTALQYVADRLKAIPPEQIGALSTPHRPA
EELFLLQKLMRGMGSGNVDHRLRQSDFALDAKAQGGFWLGMPVTYMSRLNRMLVVGSNLRKDHPLMAHRIREAVRWYGEL
NLINAADDEFLGKVHAKRIVAPSQLAGALAGVCVALAELKNQAVPKIAAHGVVDEVARKMAASLAGGETRAVFLGNMAQH
HPAYSQIHALAQEVAALAGASFGVLGEAANSVGAVAVGAIPGRGPLGQPAVAGLNAQEMLAKPLRAYLLLGVEAELDTYD
PVAAMASIDAADFVVVMSPYKGKSLDYADVLLPIAPWTETSGTFINTEGRVQSFAAVVKPLAETRPAWKVLRVLGNLLGL
AGFEHADSKEVLRDALGETPIGSVQAFLNNAVSDVDMQPAPAGEHLERVAEVPIYQTDAVVRRAPSLQRTQDGALPVARM
HSRLIARLGLEEDGRVSVRQTASALTLKVQRDDLLPDNCVRIPSGHPLTAGLGPMFGPITAEPV

Sequences:

>Translated_784_residues
MATLNIEIDGRALQVESGDTIMDAANQAGITIPHFCYHKKLSIAANCRMCLVQVEKAPKPLPACATPVTEGMKVHTRSEY
AINAQKGVMEFLLINHPLDCPICDQGGECTLQDLAVGYGGSSSRYQEIKRVVREKNLGPLIATDMTRCIHCSRCVRFGQE
IAGMMELGMPGRGEHTEVMPFLEGQVASELSGNVIDLCPVGALTSKPFRYTARPWELSRRPSISPHDSLGSNLEVHVKNN
KVMRVVPRENEDVNECWLADRDRFSYEGLNTAERLTWPMIKQDGQWIETDWRTALQYVADRLKAIPPEQIGALSTPHRPA
EELFLLQKLMRGMGSGNVDHRLRQSDFALDAKAQGGFWLGMPVTYMSRLNRMLVVGSNLRKDHPLMAHRIREAVRWYGEL
NLINAADDEFLGKVHAKRIVAPSQLAGALAGVCVALAELKNQAVPKIAAHGVVDEVARKMAASLAGGETRAVFLGNMAQH
HPAYSQIHALAQEVAALAGASFGVLGEAANSVGAVAVGAIPGRGPLGQPAVAGLNAQEMLAKPLRAYLLLGVEAELDTYD
PVAAMASIDAADFVVVMSPYKGKSLDYADVLLPIAPWTETSGTFINTEGRVQSFAAVVKPLAETRPAWKVLRVLGNLLGL
AGFEHADSKEVLRDALGETPIGSVQAFLNNAVSDVDMQPAPAGEHLERVAEVPIYQTDAVVRRAPSLQRTQDGALPVARM
HSRLIARLGLEEDGRVSVRQTASALTLKVQRDDLLPDNCVRIPSGHPLTAGLGPMFGPITAEPV
>Mature_783_residues
ATLNIEIDGRALQVESGDTIMDAANQAGITIPHFCYHKKLSIAANCRMCLVQVEKAPKPLPACATPVTEGMKVHTRSEYA
INAQKGVMEFLLINHPLDCPICDQGGECTLQDLAVGYGGSSSRYQEIKRVVREKNLGPLIATDMTRCIHCSRCVRFGQEI
AGMMELGMPGRGEHTEVMPFLEGQVASELSGNVIDLCPVGALTSKPFRYTARPWELSRRPSISPHDSLGSNLEVHVKNNK
VMRVVPRENEDVNECWLADRDRFSYEGLNTAERLTWPMIKQDGQWIETDWRTALQYVADRLKAIPPEQIGALSTPHRPAE
ELFLLQKLMRGMGSGNVDHRLRQSDFALDAKAQGGFWLGMPVTYMSRLNRMLVVGSNLRKDHPLMAHRIREAVRWYGELN
LINAADDEFLGKVHAKRIVAPSQLAGALAGVCVALAELKNQAVPKIAAHGVVDEVARKMAASLAGGETRAVFLGNMAQHH
PAYSQIHALAQEVAALAGASFGVLGEAANSVGAVAVGAIPGRGPLGQPAVAGLNAQEMLAKPLRAYLLLGVEAELDTYDP
VAAMASIDAADFVVVMSPYKGKSLDYADVLLPIAPWTETSGTFINTEGRVQSFAAVVKPLAETRPAWKVLRVLGNLLGLA
GFEHADSKEVLRDALGETPIGSVQAFLNNAVSDVDMQPAPAGEHLERVAEVPIYQTDAVVRRAPSLQRTQDGALPVARMH
SRLIARLGLEEDGRVSVRQTASALTLKVQRDDLLPDNCVRIPSGHPLTAGLGPMFGPITAEPV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=648, Percent_Identity=35.6481481481481, Blast_Score=400, Evalue=1e-111,
Organism=Escherichia coli, GI145693161, Length=659, Percent_Identity=28.6798179059181, Blast_Score=233, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17565758, Length=743, Percent_Identity=33.9165545087483, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI32566231, Length=627, Percent_Identity=36.682615629984, Blast_Score=376, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI193209088, Length=251, Percent_Identity=50.996015936255, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24640559, Length=645, Percent_Identity=37.6744186046512, Blast_Score=391, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24640557, Length=645, Percent_Identity=37.6744186046512, Blast_Score=391, Evalue=1e-108,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 84903; Mature: 84772

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLNIEIDGRALQVESGDTIMDAANQAGITIPHFCYHKKLSIAANCRMCLVQVEKAPKP
CEEEEEEECCEEEEECCCCHHHHHHCCCCCCCCHHHHHCCHHHHHCCCEEEEEHHCCCCC
LPACATPVTEGMKVHTRSEYAINAQKGVMEFLLINHPLDCPICDQGGECTLQDLAVGYGG
CCCCCCCHHCCCEEEECCCEEECHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHCCCCC
SSSRYQEIKRVVREKNLGPLIATDMTRCIHCSRCVRFGQEIAGMMELGMPGRGEHTEVMP
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECH
FLEGQVASELSGNVIDLCPVGALTSKPFRYTARPWELSRRPSISPHDSLGSNLEVHVKNN
HHHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEECC
KVMRVVPRENEDVNECWLADRDRFSYEGLNTAERLTWPMIKQDGQWIETDWRTALQYVAD
CEEEECCCCCCCHHHHHCCCCCCCCCCCCCHHHHHCCHHHHCCCCEEHHHHHHHHHHHHH
RLKAIPPEQIGALSTPHRPAEELFLLQKLMRGMGSGNVDHRLRQSDFALDAKAQGGFWLG
HHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCEEEC
MPVTYMSRLNRMLVVGSNLRKDHPLMAHRIREAVRWYGELNLINAADDEFLGKVHAKRIV
CHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCC
APSQLAGALAGVCVALAELKNQAVPKIAAHGVVDEVARKMAASLAGGETRAVFLGNMAQH
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHH
HPAYSQIHALAQEVAALAGASFGVLGEAANSVGAVAVGAIPGRGPLGQPAVAGLNAQEML
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHCCCCHHHHH
AKPLRAYLLLGVEAELDTYDPVAAMASIDAADFVVVMSPYKGKSLDYADVLLPIAPWTET
HHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCHHHHEEECCCCCCC
SGTFINTEGRVQSFAAVVKPLAETRPAWKVLRVLGNLLGLAGFEHADSKEVLRDALGETP
CCCEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
IGSVQAFLNNAVSDVDMQPAPAGEHLERVAEVPIYQTDAVVRRAPSLQRTQDGALPVARM
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCHHHH
HSRLIARLGLEEDGRVSVRQTASALTLKVQRDDLLPDNCVRIPSGHPLTAGLGPMFGPIT
HHHHHHHHCCCCCCCCHHHHCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCC
AEPV
CCCC
>Mature Secondary Structure 
ATLNIEIDGRALQVESGDTIMDAANQAGITIPHFCYHKKLSIAANCRMCLVQVEKAPKP
EEEEEEECCEEEEECCCCHHHHHHCCCCCCCCHHHHHCCHHHHHCCCEEEEEHHCCCCC
LPACATPVTEGMKVHTRSEYAINAQKGVMEFLLINHPLDCPICDQGGECTLQDLAVGYGG
CCCCCCCHHCCCEEEECCCEEECHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHCCCCC
SSSRYQEIKRVVREKNLGPLIATDMTRCIHCSRCVRFGQEIAGMMELGMPGRGEHTEVMP
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECH
FLEGQVASELSGNVIDLCPVGALTSKPFRYTARPWELSRRPSISPHDSLGSNLEVHVKNN
HHHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEECC
KVMRVVPRENEDVNECWLADRDRFSYEGLNTAERLTWPMIKQDGQWIETDWRTALQYVAD
CEEEECCCCCCCHHHHHCCCCCCCCCCCCCHHHHHCCHHHHCCCCEEHHHHHHHHHHHHH
RLKAIPPEQIGALSTPHRPAEELFLLQKLMRGMGSGNVDHRLRQSDFALDAKAQGGFWLG
HHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCEEEC
MPVTYMSRLNRMLVVGSNLRKDHPLMAHRIREAVRWYGELNLINAADDEFLGKVHAKRIV
CHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCC
APSQLAGALAGVCVALAELKNQAVPKIAAHGVVDEVARKMAASLAGGETRAVFLGNMAQH
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHH
HPAYSQIHALAQEVAALAGASFGVLGEAANSVGAVAVGAIPGRGPLGQPAVAGLNAQEML
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHCCCCHHHHH
AKPLRAYLLLGVEAELDTYDPVAAMASIDAADFVVVMSPYKGKSLDYADVLLPIAPWTET
HHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCHHHHEEECCCCCCC
SGTFINTEGRVQSFAAVVKPLAETRPAWKVLRVLGNLLGLAGFEHADSKEVLRDALGETP
CCCEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
IGSVQAFLNNAVSDVDMQPAPAGEHLERVAEVPIYQTDAVVRRAPSLQRTQDGALPVARM
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCHHHH
HSRLIARLGLEEDGRVSVRQTASALTLKVQRDDLLPDNCVRIPSGHPLTAGLGPMFGPIT
HHHHHHHHCCCCCCCCHHHHCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCC
AEPV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA