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The map label for this gene is udg [H]

Identifier: 74316979

GI number: 74316979

Start: 1022931

End: 1024253

Strand: Direct

Name: udg [H]

Synonym: Tbd_0961

Alternate gene names: 74316979

Gene position: 1022931-1024253 (Clockwise)

Preceding gene: 74316978

Following gene: 74316980

Centisome position: 35.15

GC content: 65.46

Gene sequence:

>1323_bases
TTGAAAATCACTGTGATCGGCACGGGCTACGTCGGCCTGGTGACCGGAACCTGCCTGGCCGAGGTCGGCAACGACGTGCT
GTGCCTCGATCTCGATCCGAAGAAGATCGAAACGTTGAAAGCCGGCGGCATCCCGATCTACGAACCCGGGCTCGAAGACA
TGGTGCAGCGCAATGTCGCCGCGGGCCGCCTGCACTTCACGACCGACATCGAGGAATCGGTGGCCTTCGGCCAGATCCAG
TTCATCGCCGTCGGCACGCCGCCTGACGAGGACGGCTCGGCCGACCTGCAGTACGTCGTCGCGGCCGCGCGCAATATCGG
GCGGCACATGGACGACTACAAGCTCGTCGTCGACAAGTCGACCGTGCCCGTGGGCACCGCCGACAAGGTCAGGGCGGCAC
TTGCCGAGGAACTGGCGAGGCGCGGCGCGGCGATCGAATTCAACGTCGCCTCCAACCCCGAATTCCTGAAAGAAGGTGCG
GCGGTCGAGGATTTCATGAAGCCCGACCGCATCGTGATCGGCACCGACAGCGAGCGCGCCACACAGCTTCTGCGCCAGCT
CTACGCGCCCTTCCAGCGCAACCACGAGCGCCTGCGCGTGATGGACGTCAGGAGCGCCGAATTGACCAAGTACGCCGCCA
ACGCGATGCTGGCGACGCGCATCTCCTTCATGAACGAACTCGCGGTCCTCGCGGAAAAGCTCGGCGCCGACATCGAGCAG
GTGCGCCACGGCATCGGCTCCGACCCGCGCATCGGTTACGACTTCCTGTATGCCGGCTGCGGCTATGGCGGGTCGTGCTT
CCCCAAGGATGTGCAGGCCCTGCGCCGTACCGGCCAGGAAAACGGCGTGCCCCTGCGCGTGCTCGACGCGGTCGAGGAGG
CCAACGACGCGCAGAAGCAGATTCTCGTGAACAAGCTCGTCGCGCGCTTCGGCAACGACCTCGAAGGCAGGCGCTTCGCG
ATGTGGGGGCTCGCGTTCAAGCCGAATACCGACGACATGCGCGAGGCGCCGAGCCGCACGATGCTCGACGCGCTCTGGGC
GATGGGTGCGAGCGTTTCCGCCTACGACCCGGCGGCGATGGACGAGACCCGCCGTATCTACGGCGAGCGGGCTGACCTGC
AACTCGTCGACAGCCCGATGGACGCCTTGAAGGGCGCCGACGCGCTGCTCATCGTGACCGAATGGAAGGTGTTTCGCAGC
CCCAACTTCGACACCCTTAAATCGCTGCTGAAGGCGCCGTTGATCTTCGACGGCCGCAACCTCTACGAGCCGCGCGCGAT
GCGCGAAATGGGCTTCGACTATTTCCCGATCGGGCGCCCGTGA

Upstream 100 bases:

>100_bases
CCGATCTGGTGATCGGCCGCCCCATCACCGGCGCGGGCGATCCGCTCGCGGCGCTCGCGGCGATTCAAGCGGACATTGAA
GAAAATCTAGGGAGAGCGTT

Downstream 100 bases:

>100_bases
CGCCGTTGCGTGACGCGATCGCGCGCACCCGCATCCTCGTCGCGGGTGACGTGATGCTCGACCGCTACTGGTTCGGCGAG
GTTTCGCGCATTTCGCCCGA

Product: UDP-glucose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKITVIGTGYVGLVTGTCLAEVGNDVLCLDLDPKKIETLKAGGIPIYEPGLEDMVQRNVAAGRLHFTTDIEESVAFGQIQ
FIAVGTPPDEDGSADLQYVVAAARNIGRHMDDYKLVVDKSTVPVGTADKVRAALAEELARRGAAIEFNVASNPEFLKEGA
AVEDFMKPDRIVIGTDSERATQLLRQLYAPFQRNHERLRVMDVRSAELTKYAANAMLATRISFMNELAVLAEKLGADIEQ
VRHGIGSDPRIGYDFLYAGCGYGGSCFPKDVQALRRTGQENGVPLRVLDAVEEANDAQKQILVNKLVARFGNDLEGRRFA
MWGLAFKPNTDDMREAPSRTMLDALWAMGASVSAYDPAAMDETRRIYGERADLQLVDSPMDALKGADALLIVTEWKVFRS
PNFDTLKSLLKAPLIFDGRNLYEPRAMREMGFDYFPIGRP

Sequences:

>Translated_440_residues
MKITVIGTGYVGLVTGTCLAEVGNDVLCLDLDPKKIETLKAGGIPIYEPGLEDMVQRNVAAGRLHFTTDIEESVAFGQIQ
FIAVGTPPDEDGSADLQYVVAAARNIGRHMDDYKLVVDKSTVPVGTADKVRAALAEELARRGAAIEFNVASNPEFLKEGA
AVEDFMKPDRIVIGTDSERATQLLRQLYAPFQRNHERLRVMDVRSAELTKYAANAMLATRISFMNELAVLAEKLGADIEQ
VRHGIGSDPRIGYDFLYAGCGYGGSCFPKDVQALRRTGQENGVPLRVLDAVEEANDAQKQILVNKLVARFGNDLEGRRFA
MWGLAFKPNTDDMREAPSRTMLDALWAMGASVSAYDPAAMDETRRIYGERADLQLVDSPMDALKGADALLIVTEWKVFRS
PNFDTLKSLLKAPLIFDGRNLYEPRAMREMGFDYFPIGRP
>Mature_440_residues
MKITVIGTGYVGLVTGTCLAEVGNDVLCLDLDPKKIETLKAGGIPIYEPGLEDMVQRNVAAGRLHFTTDIEESVAFGQIQ
FIAVGTPPDEDGSADLQYVVAAARNIGRHMDDYKLVVDKSTVPVGTADKVRAALAEELARRGAAIEFNVASNPEFLKEGA
AVEDFMKPDRIVIGTDSERATQLLRQLYAPFQRNHERLRVMDVRSAELTKYAANAMLATRISFMNELAVLAEKLGADIEQ
VRHGIGSDPRIGYDFLYAGCGYGGSCFPKDVQALRRTGQENGVPLRVLDAVEEANDAQKQILVNKLVARFGNDLEGRRFA
MWGLAFKPNTDDMREAPSRTMLDALWAMGASVSAYDPAAMDETRRIYGERADLQLVDSPMDALKGADALLIVTEWKVFRS
PNFDTLKSLLKAPLIFDGRNLYEPRAMREMGFDYFPIGRP

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=464, Percent_Identity=35.1293103448276, Blast_Score=252, Evalue=5e-67,
Organism=Homo sapiens, GI296040438, Length=366, Percent_Identity=36.0655737704918, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI296040443, Length=312, Percent_Identity=35.8974358974359, Blast_Score=176, Evalue=5e-44,
Organism=Escherichia coli, GI1788340, Length=366, Percent_Identity=29.2349726775956, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI48994968, Length=420, Percent_Identity=29.0476190476191, Blast_Score=144, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17560350, Length=469, Percent_Identity=35.3944562899787, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI17136908, Length=466, Percent_Identity=34.7639484978541, Blast_Score=252, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48463; Mature: 48463

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITVIGTGYVGLVTGTCLAEVGNDVLCLDLDPKKIETLKAGGIPIYEPGLEDMVQRNVA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHCHH
AGRLHFTTDIEESVAFGQIQFIAVGTPPDEDGSADLQYVVAAARNIGRHMDDYKLVVDKS
CCEEEEECCHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTADKVRAALAEELARRGAAIEFNVASNPEFLKEGAAVEDFMKPDRIVIGTDSERA
CCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCHHH
TQLLRQLYAPFQRNHERLRVMDVRSAELTKYAANAMLATRISFMNELAVLAEKLGADIEQ
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRHGIGSDPRIGYDFLYAGCGYGGSCFPKDVQALRRTGQENGVPLRVLDAVEEANDAQKQ
HHHCCCCCCCCCHHHHEECCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
ILVNKLVARFGNDLEGRRFAMWGLAFKPNTDDMREAPSRTMLDALWAMGASVSAYDPAAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCHHH
DETRRIYGERADLQLVDSPMDALKGADALLIVTEWKVFRSPNFDTLKSLLKAPLIFDGRN
HHHHHHHCCCCCEEEECCHHHHHCCCCEEEEEEEEHHHCCCCHHHHHHHHHCCCEECCCC
LYEPRAMREMGFDYFPIGRP
CCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKITVIGTGYVGLVTGTCLAEVGNDVLCLDLDPKKIETLKAGGIPIYEPGLEDMVQRNVA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHCHH
AGRLHFTTDIEESVAFGQIQFIAVGTPPDEDGSADLQYVVAAARNIGRHMDDYKLVVDKS
CCEEEEECCHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTADKVRAALAEELARRGAAIEFNVASNPEFLKEGAAVEDFMKPDRIVIGTDSERA
CCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCHHH
TQLLRQLYAPFQRNHERLRVMDVRSAELTKYAANAMLATRISFMNELAVLAEKLGADIEQ
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRHGIGSDPRIGYDFLYAGCGYGGSCFPKDVQALRRTGQENGVPLRVLDAVEEANDAQKQ
HHHCCCCCCCCCHHHHEECCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
ILVNKLVARFGNDLEGRRFAMWGLAFKPNTDDMREAPSRTMLDALWAMGASVSAYDPAAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCHHH
DETRRIYGERADLQLVDSPMDALKGADALLIVTEWKVFRSPNFDTLKSLLKAPLIFDGRN
HHHHHHHCCCCCEEEECCHHHHHCCCCEEEEEEEEHHHCCCCHHHHHHHHHCCCEECCCC
LYEPRAMREMGFDYFPIGRP
CCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]