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The map label for this gene is fabZ

Identifier: 74316814

GI number: 74316814

Start: 839602

End: 840039

Strand: Direct

Name: fabZ

Synonym: Tbd_0796

Alternate gene names: 74316814

Gene position: 839602-840039 (Clockwise)

Preceding gene: 74316813

Following gene: 74316815

Centisome position: 28.85

GC content: 61.42

Gene sequence:

>438_bases
ATGGACATCGAGCAGGTGATGCAGTACCTGCCGCATCGTTACCCCTTCCTGCTGGTCGACAAGGTCACCGAGCTCGAACT
CGGCAAGCGCATCACCGCAGTCAAGAACGTCACCATCAACGAGCCTTTCTTCAACGGCCATTTCCCCGGCGCACCGGTGA
TGCCTGGCGTGCTGATTCTCGAAGCGATGGCGCAGGCGGCGGGCATCCTATCGTTCAAGACCAAGAATTACTCGCCGGAG
CAGATCGGCATCATCTACTTCGCCGGCATTGACGGCGCGCGCTTCAAGAAGCCCGTCAAACCGGGCGATCAGCTCGTGCT
CAAGGCCGAGATCGTGCGCGAAGTGCGTGGCATCTGGAAGTACACCGGACGTGCCGAGGTCGACGGCGCGCTGGTCGCCG
AGGCCGAATTGATGGCGACGCTGCGCGACAAACCCTGA

Upstream 100 bases:

>100_bases
GGCAGAAGAACGCAGTCCACATGCGTAACCTCGACAAGCTCGTCACCCGCGTCAAGCAGCTCGAGAAAAGGCTCAACGAA
CTGGAAAACAAGACATGATC

Downstream 100 bases:

>100_bases
GATGGCGACGATTCACCCCACAGCGCTAGTCGCGCCGGGCGCGCGGCTGGCCGACGACGTCGAGATCGGGCCTTACAGCG
TGATCGGCGAGCACGTCGAA

Product: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MDIEQVMQYLPHRYPFLLVDKVTELELGKRITAVKNVTINEPFFNGHFPGAPVMPGVLILEAMAQAAGILSFKTKNYSPE
QIGIIYFAGIDGARFKKPVKPGDQLVLKAEIVREVRGIWKYTGRAEVDGALVAEAELMATLRDKP

Sequences:

>Translated_145_residues
MDIEQVMQYLPHRYPFLLVDKVTELELGKRITAVKNVTINEPFFNGHFPGAPVMPGVLILEAMAQAAGILSFKTKNYSPE
QIGIIYFAGIDGARFKKPVKPGDQLVLKAEIVREVRGIWKYTGRAEVDGALVAEAELMATLRDKP
>Mature_145_residues
MDIEQVMQYLPHRYPFLLVDKVTELELGKRITAVKNVTINEPFFNGHFPGAPVMPGVLILEAMAQAAGILSFKTKNYSPE
QIGIIYFAGIDGARFKKPVKPGDQLVLKAEIVREVRGIWKYTGRAEVDGALVAEAELMATLRDKP

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=140, Percent_Identity=54.2857142857143, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_THIDA (Q3SKN0)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314554.1
- ProteinModelPortal:   Q3SKN0
- SMR:   Q3SKN0
- STRING:   Q3SKN0
- GeneID:   3673493
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0796
- NMPDR:   fig|292415.3.peg.103
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   Q3SKN0
- BioCyc:   TDEN292415:TBD_0796-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16128; Mature: 16128

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: ACT_SITE 47-47

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIEQVMQYLPHRYPFLLVDKVTELELGKRITAVKNVTINEPFFNGHFPGAPVMPGVLIL
CCHHHHHHHCCCCCCEEEECCHHHHHHCCHHHHHCCCEECCCCCCCCCCCCCCCHHHHHH
EAMAQAAGILSFKTKNYSPEQIGIIYFAGIDGARFKKPVKPGDQLVLKAEIVREVRGIWK
HHHHHHHHHEEEECCCCCCCEEEEEEEECCCCHHCCCCCCCCHHEEHHHHHHHHHHHHHH
YTGRAEVDGALVAEAELMATLRDKP
CCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIEQVMQYLPHRYPFLLVDKVTELELGKRITAVKNVTINEPFFNGHFPGAPVMPGVLIL
CCHHHHHHHCCCCCCEEEECCHHHHHHCCHHHHHCCCEECCCCCCCCCCCCCCCHHHHHH
EAMAQAAGILSFKTKNYSPEQIGIIYFAGIDGARFKKPVKPGDQLVLKAEIVREVRGIWK
HHHHHHHHHEEEECCCCCCCEEEEEEEECCCCHHCCCCCCCCHHEEHHHHHHHHHHHHHH
YTGRAEVDGALVAEAELMATLRDKP
CCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA