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The map label for this gene is comM [H]

Identifier: 74316255

GI number: 74316255

Start: 260725

End: 262212

Strand: Reverse

Name: comM [H]

Synonym: Tbd_0237

Alternate gene names: 74316255

Gene position: 262212-260725 (Counterclockwise)

Preceding gene: 74316256

Following gene: 74316254

Centisome position: 9.01

GC content: 72.24

Gene sequence:

>1488_bases
GTGGGCGTCGCCGTCGTCAAGAGCCGCGCGCTCGCCGGCATGAACGCGCCGGAGGTTGTCGTCGAGGCGCACCTCGCCAA
CGGCCTGCCCGCGTTCACGCTCGTCGGCCTGCCCGAGACCGAGGTCAAGGAGGCGCGCGACCGCGTGCGCGCGGCGATCC
AGAACGCCGGCTACGAGTTTCCGGCGCGGCGGATCACGGTCAATCTCGCGCCCGCCGACCTGCCCAAGGAATCGGGGCGC
TTCGATCTGCCGATCGCGCTCGCGATCCTCGCCGCATCCGGGCAGGCGCCGGGCGACAAACTCAAGGAGGCCGAATTTGC
CGGCGAACTCGCGCTGACCGGAGAACTGCGCCCGGTCCGCGGAGCGCTCGCGATGGCGTTGGCGACGCGCGCAGCCGGTT
GCAAGCTCGTTTTGCCGGCGCAGTCGGCCAGCGAGGCGGCGCTCGCGCGGGGCGTCGAAACCTATGGCGCGACGAGCCTG
CTCGAGGTCTGCGCGTGGCTCGCGGGTCAGGGCACGCTGTGCGAAGCGGCTGCCGACGCGGATTCGCCTGCCGCAACCTA
TCCCGATTTCGCCGACGTCAAAGGCCAGGCCGGCGCGCGGCGCGCGCTCGAAGTCGCGGCGGCCGGCGGCCACTCGGTTT
TGATGGCTGGCCCGCCCGGGACCGGCAAGTCGATGCTCGCCGCGCGCTTTCCCGGGATCCTGCCGGCAATGGACGAGGCC
GAGGCACTCGAGGCTGCGGCGGTCGCTTCGCTCAACGGCGGGTTCCGCCCCGAGCACTGGGGCCGCCGCCCCTACCGCGC
GCCTCACCACACGGCCTCGGCGGTCGCGCTGGTCGGCGGCGGCAACAACCCGCGTCCGGGCGAAATTTCGCTCGCCCACC
ACGGTGTGCTGTTCCTCGACGAGCTGCCCGAGTTTCCGCGCCAGGTGCTCGAAGTGCTGCGCGAGCCGCTCGAGAGCGGC
CACATCACGATCTCGCGCGCCGCGCGGCAGGCCGACTTTCCGGCGCGGTTTCAGCTGGTCGCCGCGATGAACCCCTGCCC
CTGCGGCTATCTCGGCCATCCGAGCCAGGCCTGCCGCGACACGCCCGACCAGATCGCGCGATACCGCGGCCGCATCTCGG
GGCCGCTGCTCGACCGCATCGACATCCAGATCAGCGTTCCGGCCTTGACCGAAGACGAGTTGTTGGCGAGCGCCGAGGGC
GAGTCGAGCGCCGAAATCCGCGCCCGCGTCGAGGCCGCGCGTGCGCGCCAGATGCAGCGCCAGGGCAAGGCCAACGCCGC
GCTCGGCACGCAGGACGTCGAGCGCTTCTGCGCGCTCGACGGCGCCGGCGAGGCGCTGCTCAAGCAGGCGATCGCACGAC
TCAAGCTCTCGGCCCGGGCTTATCACCGCGTGCTCCGGCTCGCGCGCAGCGTCGCGGATCTCGCGGGCAGCGACGCGATC
ACCACGACCCACCTCGCCGAGGCGATCCAATACCGGCGACAGGCATGA

Upstream 100 bases:

>100_bases
GCCGCGGTGCTCGCGCGCACGCGCGAAAAGCTGGGCCAACTCGAGGCCCGGTTGGCCGATCTGGAAAAACACGAGCGGCA
GGCGGACGAAGGCTGAAGCC

Downstream 100 bases:

>100_bases
GCGACCCGCTTGAATCGTGGCATGAAGAAAAGCGTTCGGCCTGGCTTTACCGGGTCGTCGCCGAATGCGAGCAGGGCACG
CCGCGCGCGGCGCTGTTCGG

Product: Mg chelatase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MGVAVVKSRALAGMNAPEVVVEAHLANGLPAFTLVGLPETEVKEARDRVRAAIQNAGYEFPARRITVNLAPADLPKESGR
FDLPIALAILAASGQAPGDKLKEAEFAGELALTGELRPVRGALAMALATRAAGCKLVLPAQSASEAALARGVETYGATSL
LEVCAWLAGQGTLCEAAADADSPAATYPDFADVKGQAGARRALEVAAAGGHSVLMAGPPGTGKSMLAARFPGILPAMDEA
EALEAAAVASLNGGFRPEHWGRRPYRAPHHTASAVALVGGGNNPRPGEISLAHHGVLFLDELPEFPRQVLEVLREPLESG
HITISRAARQADFPARFQLVAAMNPCPCGYLGHPSQACRDTPDQIARYRGRISGPLLDRIDIQISVPALTEDELLASAEG
ESSAEIRARVEAARARQMQRQGKANAALGTQDVERFCALDGAGEALLKQAIARLKLSARAYHRVLRLARSVADLAGSDAI
TTTHLAEAIQYRRQA

Sequences:

>Translated_495_residues
MGVAVVKSRALAGMNAPEVVVEAHLANGLPAFTLVGLPETEVKEARDRVRAAIQNAGYEFPARRITVNLAPADLPKESGR
FDLPIALAILAASGQAPGDKLKEAEFAGELALTGELRPVRGALAMALATRAAGCKLVLPAQSASEAALARGVETYGATSL
LEVCAWLAGQGTLCEAAADADSPAATYPDFADVKGQAGARRALEVAAAGGHSVLMAGPPGTGKSMLAARFPGILPAMDEA
EALEAAAVASLNGGFRPEHWGRRPYRAPHHTASAVALVGGGNNPRPGEISLAHHGVLFLDELPEFPRQVLEVLREPLESG
HITISRAARQADFPARFQLVAAMNPCPCGYLGHPSQACRDTPDQIARYRGRISGPLLDRIDIQISVPALTEDELLASAEG
ESSAEIRARVEAARARQMQRQGKANAALGTQDVERFCALDGAGEALLKQAIARLKLSARAYHRVLRLARSVADLAGSDAI
TTTHLAEAIQYRRQA
>Mature_494_residues
GVAVVKSRALAGMNAPEVVVEAHLANGLPAFTLVGLPETEVKEARDRVRAAIQNAGYEFPARRITVNLAPADLPKESGRF
DLPIALAILAASGQAPGDKLKEAEFAGELALTGELRPVRGALAMALATRAAGCKLVLPAQSASEAALARGVETYGATSLL
EVCAWLAGQGTLCEAAADADSPAATYPDFADVKGQAGARRALEVAAAGGHSVLMAGPPGTGKSMLAARFPGILPAMDEAE
ALEAAAVASLNGGFRPEHWGRRPYRAPHHTASAVALVGGGNNPRPGEISLAHHGVLFLDELPEFPRQVLEVLREPLESGH
ITISRAARQADFPARFQLVAAMNPCPCGYLGHPSQACRDTPDQIARYRGRISGPLLDRIDIQISVPALTEDELLASAEGE
SSAEIRARVEAARARQMQRQGKANAALGTQDVERFCALDGAGEALLKQAIARLKLSARAYHRVLRLARSVADLAGSDAIT
TTHLAEAIQYRRQA

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=496, Percent_Identity=51.2096774193548, Blast_Score=483, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 51957; Mature: 51826

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVAVVKSRALAGMNAPEVVVEAHLANGLPAFTLVGLPETEVKEARDRVRAAIQNAGYEF
CCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCC
PARRITVNLAPADLPKESGRFDLPIALAILAASGQAPGDKLKEAEFAGELALTGELRPVR
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCCCHHH
GALAMALATRAAGCKLVLPAQSASEAALARGVETYGATSLLEVCAWLAGQGTLCEAAADA
HHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEHHHCCC
DSPAATYPDFADVKGQAGARRALEVAAAGGHSVLMAGPPGTGKSMLAARFPGILPAMDEA
CCCCCCCCCHHHCCCCCCHHHHHHHEECCCCEEEEECCCCCCHHHHHHHCCCCCCCCCHH
EALEAAAVASLNGGFRPEHWGRRPYRAPHHTASAVALVGGGNNPRPGEISLAHHGVLFLD
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEHH
ELPEFPRQVLEVLREPLESGHITISRAARQADFPARFQLVAAMNPCPCGYLGHPSQACRD
HCCHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCHHEEEEEECCCCCCCCCCCCHHHHCC
TPDQIARYRGRISGPLLDRIDIQISVPALTEDELLASAEGESSAEIRARVEAARARQMQR
CHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QGKANAALGTQDVERFCALDGAGEALLKQAIARLKLSARAYHRVLRLARSVADLAGSDAI
HCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
TTTHLAEAIQYRRQA
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
GVAVVKSRALAGMNAPEVVVEAHLANGLPAFTLVGLPETEVKEARDRVRAAIQNAGYEF
CCHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCC
PARRITVNLAPADLPKESGRFDLPIALAILAASGQAPGDKLKEAEFAGELALTGELRPVR
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCCCHHH
GALAMALATRAAGCKLVLPAQSASEAALARGVETYGATSLLEVCAWLAGQGTLCEAAADA
HHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEHHHCCC
DSPAATYPDFADVKGQAGARRALEVAAAGGHSVLMAGPPGTGKSMLAARFPGILPAMDEA
CCCCCCCCCHHHCCCCCCHHHHHHHEECCCCEEEEECCCCCCHHHHHHHCCCCCCCCCHH
EALEAAAVASLNGGFRPEHWGRRPYRAPHHTASAVALVGGGNNPRPGEISLAHHGVLFLD
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEHH
ELPEFPRQVLEVLREPLESGHITISRAARQADFPARFQLVAAMNPCPCGYLGHPSQACRD
HCCHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCHHEEEEEECCCCCCCCCCCCHHHHCC
TPDQIARYRGRISGPLLDRIDIQISVPALTEDELLASAEGESSAEIRARVEAARARQMQR
CHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QGKANAALGTQDVERFCALDGAGEALLKQAIARLKLSARAYHRVLRLARSVADLAGSDAI
HCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
TTTHLAEAIQYRRQA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]