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The map label for this gene is prmA

Identifier: 74316198

GI number: 74316198

Start: 192792

End: 193682

Strand: Reverse

Name: prmA

Synonym: Tbd_0180

Alternate gene names: 74316198

Gene position: 193682-192792 (Counterclockwise)

Preceding gene: 74316199

Following gene: 74316197

Centisome position: 6.66

GC content: 70.26

Gene sequence:

>891_bases
ATGCCCTGGCAATCCGTCCGCATCCTCGTCGATTCCGTTCAGGCCGAACCCCTGTCGGACGCGCTCATGGAAGCGGGCGC
GCTGTCGGTCTCACTCGAGGACGCCGACGCCGGGACCGTCGACGAAACGCCGCTCTTCGGCGAGCCGGATCACCCGAGCG
CTGAACTCTGGCCGCACAGCATCGCGGTCGTGCTGCTCGAAGCCGACGCCGACGTCGCCGAGACCTTGCGCGCGGCGGCG
GCGCAGGCCGGCGTCGCGGCGCCGCTCGACTACACGGTCGAGACCGTCGCGGAACAGGACTGGGTGCGGCTGACCCAATC
GCAGTTCGATCCGATCCCAATCTCGGCACGGCTCTGGATCGTGCCGACCTGGCACGAAGCGCCCGACAGCCGCGCGCTCA
ATCTCAAGCTCGACCCCGGCCTCGCCTTCGGCACCGGCAGCCATCCGACGACGCGGCTGTGCCTGCGCTGGCTCGACGCG
AACCTGCGCGGCGGCGAAACCCTGCTCGACTACGGCTGCGGCTCAGGGATCCTCGCGATCGCGGCCGCCAAACTCGGCGC
GCGCCGCGTCGAAGGCGTCGACATCGATCCACAGGCCGTCAGCGCGTCGCGCGACAACGCCGCGCTCAACGAGGTCGATG
CCCATTTCGGCCTGCCTGGGGAGCTCGCCGCCGGCGAGTACGACGTCGTCGTCGCCAACATCCTGACCAATCCCCTCAAG
GCGATGGCGCCGCTGCTCGCCGGCCGCGTGCGCAGCGGCGGAAGCCTGGTCCTCTCGGGCATCCTCGCCGAGCAGGCCGA
GGATGTCATGGCGGTCTACCGGCCCTGGTTCGTTTTCGACGCGCCGGCGAGCGACGAGGGATGGGTCCGTCTGGTCGGAG
TCAAGCGGTGA

Upstream 100 bases:

>100_bases
ATCAAACTAGGCGCGAAGCACAAAGCCCCCTGACCCCTGACCCCTAGCCCCTAGCCCCTAGCCCCTGGCCCCTGGCCCCT
GGCCCCCAAACCCTAAACCG

Downstream 100 bases:

>100_bases
GCTACCGCACCACCTGTCCGCAGTGCGCGAGCATATTCCGCCTCGGCGACGCGCAACTCGCCGCCGCGGCGGGCTGGGCG
CAATGCAGCGTATGCGGTGC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPWQSVRILVDSVQAEPLSDALMEAGALSVSLEDADAGTVDETPLFGEPDHPSAELWPHSIAVVLLEADADVAETLRAAA
AQAGVAAPLDYTVETVAEQDWVRLTQSQFDPIPISARLWIVPTWHEAPDSRALNLKLDPGLAFGTGSHPTTRLCLRWLDA
NLRGGETLLDYGCGSGILAIAAAKLGARRVEGVDIDPQAVSASRDNAALNEVDAHFGLPGELAAGEYDVVVANILTNPLK
AMAPLLAGRVRSGGSLVLSGILAEQAEDVMAVYRPWFVFDAPASDEGWVRLVGVKR

Sequences:

>Translated_296_residues
MPWQSVRILVDSVQAEPLSDALMEAGALSVSLEDADAGTVDETPLFGEPDHPSAELWPHSIAVVLLEADADVAETLRAAA
AQAGVAAPLDYTVETVAEQDWVRLTQSQFDPIPISARLWIVPTWHEAPDSRALNLKLDPGLAFGTGSHPTTRLCLRWLDA
NLRGGETLLDYGCGSGILAIAAAKLGARRVEGVDIDPQAVSASRDNAALNEVDAHFGLPGELAAGEYDVVVANILTNPLK
AMAPLLAGRVRSGGSLVLSGILAEQAEDVMAVYRPWFVFDAPASDEGWVRLVGVKR
>Mature_295_residues
PWQSVRILVDSVQAEPLSDALMEAGALSVSLEDADAGTVDETPLFGEPDHPSAELWPHSIAVVLLEADADVAETLRAAAA
QAGVAAPLDYTVETVAEQDWVRLTQSQFDPIPISARLWIVPTWHEAPDSRALNLKLDPGLAFGTGSHPTTRLCLRWLDAN
LRGGETLLDYGCGSGILAIAAAKLGARRVEGVDIDPQAVSASRDNAALNEVDAHFGLPGELAAGEYDVVVANILTNPLKA
MAPLLAGRVRSGGSLVLSGILAEQAEDVMAVYRPWFVFDAPASDEGWVRLVGVKR

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=302, Percent_Identity=45.0331125827815, Blast_Score=211, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_THIDA (Q3SMB4)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_313938.1
- ProteinModelPortal:   Q3SMB4
- SMR:   Q3SMB4
- STRING:   Q3SMB4
- GeneID:   3673626
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0180
- NMPDR:   fig|292415.3.peg.129
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- PhylomeDB:   Q3SMB4
- ProtClustDB:   PRK00517
- BioCyc:   TDEN292415:TBD_0180-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31400; Mature: 31268

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWQSVRILVDSVQAEPLSDALMEAGALSVSLEDADAGTVDETPLFGEPDHPSAELWPHS
CCCHHHHHEEHHHCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCE
IAVVLLEADADVAETLRAAAAQAGVAAPLDYTVETVAEQDWVRLTQSQFDPIPISARLWI
EEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
VPTWHEAPDSRALNLKLDPGLAFGTGSHPTTRLCLRWLDANLRGGETLLDYGCGSGILAI
EECCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHH
AAAKLGARRVEGVDIDPQAVSASRDNAALNEVDAHFGLPGELAAGEYDVVVANILTNPLK
HHHHHCHHHCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHCHHH
AMAPLLAGRVRSGGSLVLSGILAEQAEDVMAVYRPWFVFDAPASDEGWVRLVGVKR
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECC
>Mature Secondary Structure 
PWQSVRILVDSVQAEPLSDALMEAGALSVSLEDADAGTVDETPLFGEPDHPSAELWPHS
CCHHHHHEEHHHCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCE
IAVVLLEADADVAETLRAAAAQAGVAAPLDYTVETVAEQDWVRLTQSQFDPIPISARLWI
EEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
VPTWHEAPDSRALNLKLDPGLAFGTGSHPTTRLCLRWLDANLRGGETLLDYGCGSGILAI
EECCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHH
AAAKLGARRVEGVDIDPQAVSASRDNAALNEVDAHFGLPGELAAGEYDVVVANILTNPLK
HHHHHCHHHCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHCHHH
AMAPLLAGRVRSGGSLVLSGILAEQAEDVMAVYRPWFVFDAPASDEGWVRLVGVKR
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA