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The map label for this gene is ycgM [C]

Identifier: 73539683

GI number: 73539683

Start: 2701556

End: 2702317

Strand: Reverse

Name: ycgM [C]

Synonym: Reut_B5863

Alternate gene names: 73539683

Gene position: 2702317-2701556 (Counterclockwise)

Preceding gene: 73539684

Following gene: 73539682

Centisome position: 99.13

GC content: 66.01

Gene sequence:

>762_bases
ATGCCCGGGTGCGCGCATAGCGCGGCACCCAGGCCCCCGCACACCCTTCTGACTGAACCGACCATGTCCTACGTCTTCAC
GCCCCCCGCTACCGTCGCCATTCCCGTTGTTGGCAGCGATGACCAGTTCGCCGTGCGCCGCGTCTACTGCGTCGGCCGCA
ACTACGCCGCCCATGCACGCGAAATGGGGTTCGATCCCGACCGCGAGCCCCCGTTCTTCTTCTGCAAGCCGGCCGACGCC
ATCGTGCCTGTGGCTGACGGCCAGACGCTGGAACTGCCCTACCCTGTACAGACGCAGAACTACCACTATGAAGCCGAGCT
GGTCGCGGTGATCGGCAAGGCCGGTTCCGACATTCCGGTCGAGCAGGCGCTGGAGCACGTTTGGGGCTACGCCGTAGGCC
TGGACATGACGCGCCGCGACCTGCAGATGAAGATGCGCGAGATGGGCCGCCCGTGGGAAATCGGCAAGGCCTTCGACGCC
TCGGCACCAGTCGCGCCGATCCATCGCGCTGCCGATATCGGCCACCCGCAAGAGGCTGCGCTCTGGCTGACCGTCAACGG
CGAAGACAAGCAGCGCAGCAATATCACGCACCTGATCTGGTCGGTGGCCGAAACAGTCGCTTACCTGTCGCAGTTCTTCC
GCCTGGAACCGGGCGATGTGATCTTCACCGGCACCCCGGAGGGTGTGGGCGCGGTCAAGGCCGGCGACACCATGGTGACC
GGCGTCGACGGCCTCGGCGAACTCAAGGTCCGCGTGGTCTGA

Upstream 100 bases:

>100_bases
GTGCTGTTCAGCTACTCCGACCGCCCGGTGCTGTCGGCGCTGAACCTGCTGCGCGAATCGCGCACCTGAGCCCCTTTCCA
CCCGATTCATCCGATCTCAT

Downstream 100 bases:

>100_bases
TATCCACGCCGGCAAGCAGCGAAGCCATCATGCAGCTCTATAGTTTCTTCAACAGCTCCACGTCCTACCGCGTGCGCATT
GCACTGGCGCTCAAGGGCCT

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MPGCAHSAAPRPPHTLLTEPTMSYVFTPPATVAIPVVGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADA
IVPVADGQTLELPYPVQTQNYHYEAELVAVIGKAGSDIPVEQALEHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDA
SAPVAPIHRAADIGHPQEAALWLTVNGEDKQRSNITHLIWSVAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGDTMVT
GVDGLGELKVRVV

Sequences:

>Translated_253_residues
MPGCAHSAAPRPPHTLLTEPTMSYVFTPPATVAIPVVGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADA
IVPVADGQTLELPYPVQTQNYHYEAELVAVIGKAGSDIPVEQALEHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDA
SAPVAPIHRAADIGHPQEAALWLTVNGEDKQRSNITHLIWSVAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGDTMVT
GVDGLGELKVRVV
>Mature_252_residues
PGCAHSAAPRPPHTLLTEPTMSYVFTPPATVAIPVVGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAI
VPVADGQTLELPYPVQTQNYHYEAELVAVIGKAGSDIPVEQALEHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDAS
APVAPIHRAADIGHPQEAALWLTVNGEDKQRSNITHLIWSVAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGDTMVTG
VDGLGELKVRVV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=40.5797101449275, Blast_Score=158, Evalue=5e-39,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=41.5, Blast_Score=157, Evalue=7e-39,
Organism=Homo sapiens, GI215422413, Length=200, Percent_Identity=41.5, Blast_Score=157, Evalue=9e-39,
Organism=Homo sapiens, GI156231349, Length=215, Percent_Identity=36.7441860465116, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI40786394, Length=215, Percent_Identity=36.2790697674419, Blast_Score=125, Evalue=3e-29,
Organism=Escherichia coli, GI1787428, Length=212, Percent_Identity=39.622641509434, Blast_Score=152, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17557057, Length=196, Percent_Identity=37.2448979591837, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6324161, Length=221, Percent_Identity=28.9592760180996, Blast_Score=113, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28571789, Length=212, Percent_Identity=36.7924528301887, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28572127, Length=216, Percent_Identity=33.7962962962963, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24663695, Length=221, Percent_Identity=28.9592760180996, Blast_Score=88, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27597; Mature: 27465

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGCAHSAAPRPPHTLLTEPTMSYVFTPPATVAIPVVGSDDQFAVRRVYCVGRNYAAHAR
CCCCCCCCCCCCCCCEEECCCCEEEECCCCEEEEEEECCCCCEEEEEEEEECCCHHHHHH
EMGFDPDREPPFFFCKPADAIVPVADGQTLELPYPVQTQNYHYEAELVAVIGKAGSDIPV
HCCCCCCCCCCEEEECCCCCEEECCCCCEEECCCCCCCCCEEEHEEEEEEEECCCCCCCH
EQALEHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDASAPVAPIHRAADIGHPQEAA
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEE
LWLTVNGEDKQRSNITHLIWSVAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGDTMVT
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCCEEEE
GVDGLGELKVRVV
CCCCCCCEEEEEC
>Mature Secondary Structure 
PGCAHSAAPRPPHTLLTEPTMSYVFTPPATVAIPVVGSDDQFAVRRVYCVGRNYAAHAR
CCCCCCCCCCCCCCEEECCCCEEEECCCCEEEEEEECCCCCEEEEEEEEECCCHHHHHH
EMGFDPDREPPFFFCKPADAIVPVADGQTLELPYPVQTQNYHYEAELVAVIGKAGSDIPV
HCCCCCCCCCCEEEECCCCCEEECCCCCEEECCCCCCCCCEEEHEEEEEEEECCCCCCCH
EQALEHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDASAPVAPIHRAADIGHPQEAA
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEE
LWLTVNGEDKQRSNITHLIWSVAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGDTMVT
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCCEEEE
GVDGLGELKVRVV
CCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]