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The map label for this gene is 73539684

Identifier: 73539684

GI number: 73539684

Start: 2702349

End: 2703395

Strand: Reverse

Name: 73539684

Synonym: Reut_B5864

Alternate gene names: NA

Gene position: 2703395-2702349 (Counterclockwise)

Preceding gene: 73539691

Following gene: 73539683

Centisome position: 99.17

GC content: 66.76

Gene sequence:

>1047_bases
ATGTCCGAACACTCGCCCGATCCCGCCCGCGTCGCGTACTACGAGCGCATCGGCCACAGCCATATGACGCCGCTGTGGGA
GTCGCTCCACAGCCTGGTGCCCCCGCAACCGCGCCCGCAGATCATCCCGGCCATCTGGAAGTACGACGCGATCCGCCCGC
TGATCATGCAAGCCGGCGCGGTCATCAGCGCCGAAGAGGCCGTGCGCCGCGTGCTGATCCTGGAGAATCCGGGGCTGCCT
GGCAAGTCGAGCATCACGTCGACGCTCTACGCCGGCCTGCAACTGATCCTGCCGGGCGAGATCGCGCCGAGCCATCGCCA
TACCCAATCAGCACTGCGCTTCATTGTCGAAGGCAAGGGGGCCTGGACCGCCGTCAACGGCGAGCGCACCACCATGCATC
CGGGCGACTTCATCATCACGCCGTCGTGGACGTGGCACGACCACGGCAACCCGAGCCTGGAGGACGGCGGAGGGCCGGTG
GTGTGGCTGGACGGCCTCGATATCCCGCTCGTTCAGCAGTTTGATGCAGGTTTTGCCGAGAACTACCCTGAGTCGCAGCA
GCCCGTGACACGCCCCGAGGGCGACAGCTTTGCGCGCTTCGGCCAGAACATGGTGCCGGTGCGCCACAAGGTCACCGACC
CGACATCGCCCATCTTCAGCTATCCGTACGATCGTTCCCGCGAAGCGCTCGACAAGCTCTACCGCAATGGCGAACTGGAC
GCGTGGGACGGCGTGAAGCTGCGCTACGTGAACCCGGCCACGGGCGGCTGGCCGATGCCGACCATCGCCACCTTCATGCA
GTACCTGCCGGCCGGCTTCCAGGGCAAGACCTATCGCAGCACCGACGCCACCGTCTACAGCGTGGTGGAAGGCCGCGGCA
CCGTGCGCATCGGCGATGCGCAGTTCCAGTTCGAGCCGCGTGATGTGTTCGTCGCGCCGTCGTGGGCACCGGTGCAGCTC
GGCGCGATGGAAGACGCCGTGCTGTTCAGCTACTCCGACCGCCCGGTGCTGTCGGCGCTGAACCTGCTGCGCGAATCGCG
CACCTGA

Upstream 100 bases:

>100_bases
TAAGAGGATTTATTCATTTCAAATCTTATATCGAGGGACGTATAACTCCAAGCAACAGCCTGGCAGCACGCCGGCGAACA
CAAAAAGCCACGGAGACAGC

Downstream 100 bases:

>100_bases
GCCCCTTTCCACCCGATTCATCCGATCTCATATGCCCGGGTGCGCGCATAGCGCGGCACCCAGGCCCCCGCACACCCTTC
TGACTGAACCGACCATGTCC

Product: gentisate 1,2-dioxygenase

Products: maleylpyruvate

Alternate protein names: Cupin 2 Domain-Containing Protein; Cupin 2 Conserved Barrel Domain Protein; Cupin 2 Barrel; Cupin 2 Conserved Barrel Domain-Containing Protein; 1 2-Dioxygenase; Gentisate 1 2-Dioxygenase Oxidoreductase Protein; Cupin 2 Protein; 1-Hydroxy-2-Naphthoate Dioxygenase; Gentisate 1 2-Dioxygenase Oxidoreductase; Dioxygenase Oxidoreductase Protein; Dioxygenase

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSEHSPDPARVAYYERIGHSHMTPLWESLHSLVPPQPRPQIIPAIWKYDAIRPLIMQAGAVISAEEAVRRVLILENPGLP
GKSSITSTLYAGLQLILPGEIAPSHRHTQSALRFIVEGKGAWTAVNGERTTMHPGDFIITPSWTWHDHGNPSLEDGGGPV
VWLDGLDIPLVQQFDAGFAENYPESQQPVTRPEGDSFARFGQNMVPVRHKVTDPTSPIFSYPYDRSREALDKLYRNGELD
AWDGVKLRYVNPATGGWPMPTIATFMQYLPAGFQGKTYRSTDATVYSVVEGRGTVRIGDAQFQFEPRDVFVAPSWAPVQL
GAMEDAVLFSYSDRPVLSALNLLRESRT

Sequences:

>Translated_348_residues
MSEHSPDPARVAYYERIGHSHMTPLWESLHSLVPPQPRPQIIPAIWKYDAIRPLIMQAGAVISAEEAVRRVLILENPGLP
GKSSITSTLYAGLQLILPGEIAPSHRHTQSALRFIVEGKGAWTAVNGERTTMHPGDFIITPSWTWHDHGNPSLEDGGGPV
VWLDGLDIPLVQQFDAGFAENYPESQQPVTRPEGDSFARFGQNMVPVRHKVTDPTSPIFSYPYDRSREALDKLYRNGELD
AWDGVKLRYVNPATGGWPMPTIATFMQYLPAGFQGKTYRSTDATVYSVVEGRGTVRIGDAQFQFEPRDVFVAPSWAPVQL
GAMEDAVLFSYSDRPVLSALNLLRESRT
>Mature_347_residues
SEHSPDPARVAYYERIGHSHMTPLWESLHSLVPPQPRPQIIPAIWKYDAIRPLIMQAGAVISAEEAVRRVLILENPGLPG
KSSITSTLYAGLQLILPGEIAPSHRHTQSALRFIVEGKGAWTAVNGERTTMHPGDFIITPSWTWHDHGNPSLEDGGGPVV
WLDGLDIPLVQQFDAGFAENYPESQQPVTRPEGDSFARFGQNMVPVRHKVTDPTSPIFSYPYDRSREALDKLYRNGELDA
WDGVKLRYVNPATGGWPMPTIATFMQYLPAGFQGKTYRSTDATVYSVVEGRGTVRIGDAQFQFEPRDVFVAPSWAPVQLG
AMEDAVLFSYSDRPVLSALNLLRESRT

Specific function: Unknown

COG id: COG3435

COG function: function code Q; Gentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.13.11.4

Molecular weight: Translated: 38676; Mature: 38545

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHSPDPARVAYYERIGHSHMTPLWESLHSLVPPQPRPQIIPAIWKYDAIRPLIMQAGA
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC
VISAEEAVRRVLILENPGLPGKSSITSTLYAGLQLILPGEIAPSHRHTQSALRFIVEGKG
EEEHHHHHCEEEEEECCCCCCCHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHEECCC
AWTAVNGERTTMHPGDFIITPSWTWHDHGNPSLEDGGGPVVWLDGLDIPLVQQFDAGFAE
CEEEECCCCEEECCCCEEECCCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHCCCHHH
NYPESQQPVTRPEGDSFARFGQNMVPVRHKVTDPTSPIFSYPYDRSREALDKLYRNGELD
CCCCCCCCCCCCCCCHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
AWDGVKLRYVNPATGGWPMPTIATFMQYLPAGFQGKTYRSTDATVYSVVEGRGTVRIGDA
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEECCCCCEEEEEECCCCEEEECCC
QFQFEPRDVFVAPSWAPVQLGAMEDAVLFSYSDRPVLSALNLLRESRT
EEEECCCEEEECCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEHSPDPARVAYYERIGHSHMTPLWESLHSLVPPQPRPQIIPAIWKYDAIRPLIMQAGA
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC
VISAEEAVRRVLILENPGLPGKSSITSTLYAGLQLILPGEIAPSHRHTQSALRFIVEGKG
EEEHHHHHCEEEEEECCCCCCCHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHEECCC
AWTAVNGERTTMHPGDFIITPSWTWHDHGNPSLEDGGGPVVWLDGLDIPLVQQFDAGFAE
CEEEECCCCEEECCCCEEECCCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHCCCHHH
NYPESQQPVTRPEGDSFARFGQNMVPVRHKVTDPTSPIFSYPYDRSREALDKLYRNGELD
CCCCCCCCCCCCCCCHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
AWDGVKLRYVNPATGGWPMPTIATFMQYLPAGFQGKTYRSTDATVYSVVEGRGTVRIGDA
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEECCCCCEEEEEECCCCEEEECCC
QFQFEPRDVFVAPSWAPVQLGAMEDAVLFSYSDRPVLSALNLLRESRT
EEEECCCEEEECCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2,5-dihydroxybenzoate; O2

Specific reaction: 2,5-dihydroxybenzoate + O2 = maleylpyruvate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA