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The map label for this gene is dapA [C]

Identifier: 73537523

GI number: 73537523

Start: 272271

End: 273185

Strand: Reverse

Name: dapA [C]

Synonym: Reut_B3688

Alternate gene names: 73537523

Gene position: 273185-272271 (Counterclockwise)

Preceding gene: 73537526

Following gene: 73537521

Centisome position: 10.02

GC content: 65.46

Gene sequence:

>915_bases
ATGACGACACCGCAAGAACTGAAGCAGATCATTTCGGAAGGCCTGCTGTCCTTCCCAGTCACCGACTTCGACACGCAAGG
CAACTTCCGGCCGGAAACGTACGTCAAGCGCCTCGAATGGCTGGCGCCCTATGGCGCATCGGCGCTGTTCGCGGCTGGCG
GCACCGGCGAGTTCTTCTCCCTGACGCCGGATGACTACTCGAACGTGATTCGCACCGCGGTGGAAACCTGCGCGGGCAAG
GTGCCCATCCTGGCTGGCGCAGGCGGCCCGACCCGCGTTGCCATCGCCTACGCTCAGGAAGCGCAGCGCCTTGGCGCCAA
GGGCATTCTGCTGATGCCCCACTACCTGACCGAAGCGTGCGAAGAAGGCATTGCCAATCACATCGAGGAAGTCTGCAAGG
CGGTGAACATCGGGGTGATCGTCTACAACCGCGCCAACTCGCGCATCGGTGCCGACCTGCTCGAACGCGTGGTCGACCGC
TGCCCGAACCTGATCGGCTTCAAGGACGGCGTCGGCGAGATCGAAGCGATGGTGCGCGTGCGCCGCAAGCTCGGTGACCG
CCTGGCCTACCTGGGCGGCCTGCCGACCGCGGAAGTCTATGCCGCCGCCTACAAGGCGCTGGGCGTGCCGGTGTATTCGT
CGGCTGTGTTCAACTTCATTCCGCGCACTGCGATGGAGTTCTACCGCGCCGTCGCCGCCGACGACCACGCGACCATCGGC
CGCCTGATCGACGACTTCTTCCTCCCCTACCTGGATATCCGCAACCGCCGTCAGGGCTATGCGGTGAGCATCGTCAAGGC
CGGCGCCCGCCTGGTCGGCTACGACGCCGGCCCCGTGCGCGCACCGCTGACGGACCTGACGGCCGACGAGACGGAAAAGC
TGGATGCGCTGATCCGCAAGCTCGGACCGCAGTAA

Upstream 100 bases:

>100_bases
GTTGTACGATGACGTACATTGATAACGCACTGCAGGAACGCGGAACGCCGCCCTGCCCCAATCCATCACCCACTGCCGCC
TCTGGCCCAGGATGAGAGAC

Downstream 100 bases:

>100_bases
GGTCGCTCCGGAACACCGGACACAGTTGGATACCCCGCCGCGAGCGGGGTATTTCTTTATGTGGCGGCCGACCTCGGCAG
AAGGAGCACGCCCTGGTCAT

Product: 5-dehydro-4-deoxyglucarate dehydratase

Products: NA

Alternate protein names: 5-keto-4-deoxy-glucarate dehydratase; KDGDH [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTTPQELKQIISEGLLSFPVTDFDTQGNFRPETYVKRLEWLAPYGASALFAAGGTGEFFSLTPDDYSNVIRTAVETCAGK
VPILAGAGGPTRVAIAYAQEAQRLGAKGILLMPHYLTEACEEGIANHIEEVCKAVNIGVIVYNRANSRIGADLLERVVDR
CPNLIGFKDGVGEIEAMVRVRRKLGDRLAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPRTAMEFYRAVAADDHATIG
RLIDDFFLPYLDIRNRRQGYAVSIVKAGARLVGYDAGPVRAPLTDLTADETEKLDALIRKLGPQ

Sequences:

>Translated_304_residues
MTTPQELKQIISEGLLSFPVTDFDTQGNFRPETYVKRLEWLAPYGASALFAAGGTGEFFSLTPDDYSNVIRTAVETCAGK
VPILAGAGGPTRVAIAYAQEAQRLGAKGILLMPHYLTEACEEGIANHIEEVCKAVNIGVIVYNRANSRIGADLLERVVDR
CPNLIGFKDGVGEIEAMVRVRRKLGDRLAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPRTAMEFYRAVAADDHATIG
RLIDDFFLPYLDIRNRRQGYAVSIVKAGARLVGYDAGPVRAPLTDLTADETEKLDALIRKLGPQ
>Mature_303_residues
TTPQELKQIISEGLLSFPVTDFDTQGNFRPETYVKRLEWLAPYGASALFAAGGTGEFFSLTPDDYSNVIRTAVETCAGKV
PILAGAGGPTRVAIAYAQEAQRLGAKGILLMPHYLTEACEEGIANHIEEVCKAVNIGVIVYNRANSRIGADLLERVVDRC
PNLIGFKDGVGEIEAMVRVRRKLGDRLAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPRTAMEFYRAVAADDHATIGR
LIDDFFLPYLDIRNRRQGYAVSIVKAGARLVGYDAGPVRAPLTDLTADETEKLDALIRKLGPQ

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Escherichia coli, GI1788823, Length=289, Percent_Identity=26.2975778546713, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082415, Length=233, Percent_Identity=27.0386266094421, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786463, Length=217, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017655
- InterPro:   IPR002220 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.41 [H]

Molecular weight: Translated: 33020; Mature: 32889

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPQELKQIISEGLLSFPVTDFDTQGNFRPETYVKRLEWLAPYGASALFAAGGTGEFFS
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCEEE
LTPDDYSNVIRTAVETCAGKVPILAGAGGPTRVAIAYAQEAQRLGAKGILLMPHYLTEAC
ECCHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCEEECHHHHHHHH
EEGIANHIEEVCKAVNIGVIVYNRANSRIGADLLERVVDRCPNLIGFKDGVGEIEAMVRV
HHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
RRKLGDRLAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPRTAMEFYRAVAADDHATIG
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RLIDDFFLPYLDIRNRRQGYAVSIVKAGARLVGYDAGPVRAPLTDLTADETEKLDALIRK
HHHHHHHHHHHHHCCCCCCCEEHHHHHCCCEEECCCCCCCCCCHHCCCCHHHHHHHHHHH
LGPQ
HCCC
>Mature Secondary Structure 
TTPQELKQIISEGLLSFPVTDFDTQGNFRPETYVKRLEWLAPYGASALFAAGGTGEFFS
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCEEE
LTPDDYSNVIRTAVETCAGKVPILAGAGGPTRVAIAYAQEAQRLGAKGILLMPHYLTEAC
ECCHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCEEECHHHHHHHH
EEGIANHIEEVCKAVNIGVIVYNRANSRIGADLLERVVDRCPNLIGFKDGVGEIEAMVRV
HHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
RRKLGDRLAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPRTAMEFYRAVAADDHATIG
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RLIDDFFLPYLDIRNRRQGYAVSIVKAGARLVGYDAGPVRAPLTDLTADETEKLDALIRK
HHHHHHHHHHHHHCCCCCCCEEHHHHHCCCEEECCCCCCCCCCHHCCCCHHHHHHHHHHH
LGPQ
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA