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The map label for this gene is nreC [H]

Identifier: 73543101

GI number: 73543101

Start: 3752143

End: 3752838

Strand: Direct

Name: nreC [H]

Synonym: Reut_A3419

Alternate gene names: 73543101

Gene position: 3752143-3752838 (Clockwise)

Preceding gene: 73543100

Following gene: 73543103

Centisome position: 98.57

GC content: 67.96

Gene sequence:

>696_bases
ATGACCCAGATATCGGACCCCGACGAACCGGAAGGCCATTCCATCGATGCGCCCGCGCGCGTGCTGCTGATCGACGACCA
TGCGCTCGTGCGTGACGGCATGCGCATGCACCTGACGCTACAACCCGACCTGTATGTGGTCGGCGAAGCCGATGGCGGCG
AGGCGGCGCTGGCGTGGCTCGAGCGAGCCGGTGCGCGCGAGCGTCCGGACCTTGTCATCACTGATATCGGCATGCGCGGC
ATGGGCGGCATCGCATTGACCGCCGCGCTGCACGAGCAGTACCCGGAAATCGCCGTGCTCGTGGTCAGCATGCACGACAA
TCTCGAATACGCACGCCAGGCGGTGCGCGCCGGTGCGCGCGGCTATGTGCTCAAGGATGCGCCCGCGGACGAGCTGATGG
CCGCGATCGAGGCGGTGCTGGCCGGACGCGTGTTCTACAGCGCCCGCATCGCGCGCGGCATGGCGGAACAGATGCCGGCG
ACCGGTCCGCTCGACGCGCTGACACGGCGCGAGCGCGACATCCTCGGCTGCATCGGCCGCGGCATGGCGAACAAGGAGAT
TGCGACGCAGCTCGGGGTATCGGTGCGCACGGTGGAAACGCACCGGCTCAATCTCAAGCGCAAGCTTGGCATCGAAGGCC
GCGCGGGGCTGGTGAAGTATGCGGTGGAGCAGGCGGGGGAAACCGAGGGCGGATAG

Upstream 100 bases:

>100_bases
TTGTTTCCGGCATCGGCGGCACCGAGCTGGTGGCCACGCTGCCGGTCGTGAAGGCGGCCGCCCGACCCACCACTCCCCTT
CCCGCAGAATCTTCGCAGTC

Downstream 100 bases:

>100_bases
GAAAACAAAAACGCCCGTCTCCGGATGAGACGGGCGTTTTGTCTTGCTGTCCTCAAATCCGCAGGACAGCAACGTGGCAG
CGAGACTTTAGCCCTCCAGC

Product: LuxR response regulator receiver

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTQISDPDEPEGHSIDAPARVLLIDDHALVRDGMRMHLTLQPDLYVVGEADGGEAALAWLERAGARERPDLVITDIGMRG
MGGIALTAALHEQYPEIAVLVVSMHDNLEYARQAVRAGARGYVLKDAPADELMAAIEAVLAGRVFYSARIARGMAEQMPA
TGPLDALTRRERDILGCIGRGMANKEIATQLGVSVRTVETHRLNLKRKLGIEGRAGLVKYAVEQAGETEGG

Sequences:

>Translated_231_residues
MTQISDPDEPEGHSIDAPARVLLIDDHALVRDGMRMHLTLQPDLYVVGEADGGEAALAWLERAGARERPDLVITDIGMRG
MGGIALTAALHEQYPEIAVLVVSMHDNLEYARQAVRAGARGYVLKDAPADELMAAIEAVLAGRVFYSARIARGMAEQMPA
TGPLDALTRRERDILGCIGRGMANKEIATQLGVSVRTVETHRLNLKRKLGIEGRAGLVKYAVEQAGETEGG
>Mature_230_residues
TQISDPDEPEGHSIDAPARVLLIDDHALVRDGMRMHLTLQPDLYVVGEADGGEAALAWLERAGARERPDLVITDIGMRGM
GGIALTAALHEQYPEIAVLVVSMHDNLEYARQAVRAGARGYVLKDAPADELMAAIEAVLAGRVFYSARIARGMAEQMPAT
GPLDALTRRERDILGCIGRGMANKEIATQLGVSVRTVETHRLNLKRKLGIEGRAGLVKYAVEQAGETEGG

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=40, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788521, Length=213, Percent_Identity=32.3943661971831, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=32.8502415458937, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=28.9855072463768, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787473, Length=189, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788712, Length=201, Percent_Identity=28.8557213930348, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788546, Length=205, Percent_Identity=27.8048780487805, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24873; Mature: 24742

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQISDPDEPEGHSIDAPARVLLIDDHALVRDGMRMHLTLQPDLYVVGEADGGEAALAWL
CCCCCCCCCCCCCCCCCCEEEEEEECHHHHHCCCEEEEEECCCEEEEECCCCCHHHHHHH
ERAGARERPDLVITDIGMRGMGGIALTAALHEQYPEIAVLVVSMHDNLEYARQAVRAGAR
HHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCC
GYVLKDAPADELMAAIEAVLAGRVFYSARIARGMAEQMPATGPLDALTRRERDILGCIGR
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
GMANKEIATQLGVSVRTVETHRLNLKRKLGIEGRAGLVKYAVEQAGETEGG
CCCCHHHHHHHCCEEEEEHHHHHCHHHHCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQISDPDEPEGHSIDAPARVLLIDDHALVRDGMRMHLTLQPDLYVVGEADGGEAALAWL
CCCCCCCCCCCCCCCCCEEEEEEECHHHHHCCCEEEEEECCCEEEEECCCCCHHHHHHH
ERAGARERPDLVITDIGMRGMGGIALTAALHEQYPEIAVLVVSMHDNLEYARQAVRAGAR
HHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCC
GYVLKDAPADELMAAIEAVLAGRVFYSARIARGMAEQMPATGPLDALTRRERDILGCIGR
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
GMANKEIATQLGVSVRTVETHRLNLKRKLGIEGRAGLVKYAVEQAGETEGG
CCCCHHHHHHHCCEEEEEHHHHHCHHHHCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA