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The map label for this gene is putA [H]

Identifier: 73543022

GI number: 73543022

Start: 3652928

End: 3656896

Strand: Reverse

Name: putA [H]

Synonym: Reut_A3340

Alternate gene names: 73543022

Gene position: 3656896-3652928 (Counterclockwise)

Preceding gene: 73543023

Following gene: 73543021

Centisome position: 96.07

GC content: 67.17

Gene sequence:

>3969_bases
ATGGCCACCACCACCCTCGGCGTCAAACTCGACGACGCTTCGCGCGATCGCCTCAAGCGTGTCGCCCAATCCATCGACCG
GACGCCGCACTGGCTGATCAAGCAGGCGATCTTCACGTATCTCGAGCAGATCGAGCGTGGCCACCTGCCGCATGAGGCGA
TGGCAGGCGGCGCAGGGGAGGCCGATGGCGCCGACGGTGCTGAGATGAGCCACGCCGATGGCGCACCGCAGCCGTTCCTG
GAATTCGCGCAAAGCATTCAGCCGCAATCCGTACTGCGCGCCGCAATTACTTCGGCCTATCGCCGTCCTGAAACCGATTG
CGTGCCGGTGCTGCTGGAGCAGGCACGCCTGCCGCAGCAACAGGCCGAAGCCGCCATCAAGATGGCCAAGAAGCTGGCCA
CCGCGCTGCGCGAGCAGAAGGTGGGCACCGGCCGCGAAGGCCTGGTGCAGGGCCTGATCCAGGAATTCTCCCTGTCGTCG
CAAGAAGGCGTAGCGCTGATGTGCCTGGCCGAGGCCCTGCTGCGCATTCCCGACAAGCCCACGCGCGACGCGCTGATCCG
CGACAAGATCAGCGGCGCCAACTGGCAGTCGCACCTGGGCCAGAGCCCATCGCTGTTCGTCAACGCCGCGACCTGGGGCC
TGCTGCTGACCGGCAAGCTGGTCGCCACCCATACCGAATCGGGCCTGAGCAAGGCGCTCACGCGCATCATCGGCAAGGGC
GGCGAACCGCTGATCCGCAAGGGCGTCGACATGGCCATGCGCCTGATGGGCGAGCAGTTCGTCACGGGCGAGACCATTTC
CGAAGCGCTGGCCAACGCGCGCAAGTACGAAGCGCAGGGCTTCCGCTATTCCTACGACATGCTTGGCGAAGCGGCGATGA
CGGAAGAGGATGCGCAGCGCTACCTCGCGTCGTACGAGCAGGCCATCCATGCGATTGGCCAGGCCTCGCGCGGCCGCGGC
ATCTATGAAGGCCCGGGCATTTCGATCAAGCTGTCGGCGCTGCATCCGCGCTACAGCCGCGCCCAGCACGAGCGGGTGAT
CAACGAGCTTTATGAGCGCCTGAAGTCGCTGACGCTGCTGGCGCGCCAGTACGACATCGGCATCAACATCGACGCCGAAG
AGGCCGACCGCCTCGAGATCTCGCTCGACCTGCTCGAACGCCTGTGCTTCGAGCCCGAGCTGGCCGGCTGGAACGGCATC
GGCTTCGTGGTGCAGGGCTACCAGAAGCGCTGCCCGTTCGTGATCGACTACCTGATCGACCTCGCGCGCCGCAGCCGCCA
CCGCCTGATGATCCGCCTGGTTAAGGGCGCCTACTGGGACAGCGAAATCAAGCGCGCCCAAGTCGAAGGCCTGGAAGGCT
ATCCGGTCTACACGCGCAAGGTCTACACCGATGTGTCGTACGTGGCCTGCGCGCGCAAGCTGCTGTCGGTGCCCGACGCG
ATTTATCCACAGTTCGCCACGCACAACGCGCACACGCTGTCGGCCATCTACCAGATCGCCGGCCATAGCTACTATCCCGG
CCAGTACGAATTCCAGTGCCTGCACGGCATGGGCGAGCCGCTGTACGACCAGGTCGTCGGCCCGATCGCCGACGGCAAGT
TCAACCGCCCGTGCCGTATCTACGCGCCGGTTGGCACGCATGAAACGCTGCTCGCCTACCTGGTGCGCCGCCTGCTCGAA
AACGGCGCCAACACCTCGTTCGTCAACCGGATTGCCGACGACACGATTTCGCTCGATGAACTGGTGGCCGACCCGGTCGC
CGTGGTCGAGACCATGCATCGCGATGAAGGCACGCTGGGCCTGCCGCATCCGAAGATCCCGTCGCCGCGCGGCCTTTATG
GCAAGTCGCGCGCGAACTCGGCGGGTATCGACCTTGCCAACGAGCATCGCCTCGCTTCGCTGTCGTCCGCGCTGCTGGCC
GGTACAAGCGAACGCGTCGTGGCCGATCCGATGCTGGGTACCGAGGTCCCGCGCGCAGCCGATGCCATCACCACGCCGGT
GCTGAACCCGGCCGACCATCGCGACGTCGTGGGCCAGGTCACTGAAGCCAGCCAGGCCGATGTCGACGCCGCGCTGCAGG
CCGCCGCCAATGCGGCACCGATCTGGCAGGCCACGCCGCCCGACGTCCGTGCCTCCGCGCTTGAACGCGCCGCCGACCTG
ATGGAAGCGCAGATGCAGTCGCTGATGGGCATCATCATGCGCGAGGCCGGCAAGACCTTCTCGAACGCGATCGCCGAAGT
GCGCGAGGCGGTGGACTTCCTGCGCTACTACGCGGCCGAAGTGCGCCGCAGCTTCGACAACGAGACGCACCGCCCGCTGG
GCCCGGTGGTCTGCATCAGCCCGTGGAATTTCCCGCTGGCGATCTTCACCGGGCAGGTGGCCGCAGCGCTGGCCGCCGGC
AATACGGTGCTGGCCAAGCCCGCCGAGCAGACGCCGCTGATTGCCGCTGCCGCGGTGCGCATCCTGCGCGAGGCCGGCGT
GCCGGCGGGTGCCGTGCAGCTGCTGCCGGGCCGTGGCGAGACCGTGGGCGCGGCACTGGTGGGCGACGCGCGCGTCAAGG
GCGTGATGTTCACGGGCTCGACCGAAGTCGCGCGTATCCTCCAGCGCAATATCGCCGGCCGTCTCGATGCCGCCGGCCGT
CCGATTCCGCTAATCGCCGAAACCGGTGGCCAGAACGCGATGATCGTCGACTCGTCTGCACTGGCCGAACAGGTCGTGGG
CGACGTAGTCAACTCCGCGTTCGACTCGGCCGGCCAGCGCTGCTCCGCGCTGCGCGTGCTGTGCCTGCAGGAAGACGTGG
CCGACCGCGTGCTCGCCATGCTCAAGGGCGCCATGAATGAACTGACCATGGCCAACCCGGACCGCCTGTCCACCGATGTG
GGCCCGGTCATCGACGAAGAAGCGCGCGGCAATATCGTGCGCCATATCGATGCGATGCGCGCCAAGGGTCGCCGCGTGCA
CCAGGCCGATCCGAATGCCCCGCAGGGCGCCAGCTGCCGCCATGGCACCTTCGTGCCGCCGACCCTGATCGAACTCGACA
GCATCGACGAACTGAAGCGCGAGGTGTTCGGCCCCGTGCTGCACGTGGTGCGCTTCCCGCGCGCCGCGCTGGACACCATG
ATCGGCCAGATCAACGGTACCAACTATGGCCTGACGATGGGGATCCACACCCGCATCGACGAGACCATCGCGCAGATCGT
GCAGCATGCCGAGGTGGGCAATCTGTACGTGAACCGCAATATCGTCGGCGCGGTGGTGGGTGTGCAGCCGTTTGGCGGCG
AGGCGCTGTCGGGCACTGGGCCGAAGGCCGGTGGCCCGTTGTACCTGCACCGCCTGCTGTCGGTCTGCCCGCAGGATGCG
GTGGTTCGCAGCGTGCGCCACGCGGAAGCGTCGGGCAACCCGCCGGCTGCGCCGGAGCGCCCAGTCGCCGCACAGGCGCT
GAAGGACTGGGCGAAGACCGAGATGCCGGAAGTCGCCGCCGCCTGCGATCGCTTTGCCGAAGCCTCGGCGGCTGGCATTT
CGGTGACGCTGCGCGGGCCGACCGGCGAGCGCAACACCTACTCGCTGCTGCCGCGCCACCATGTCCTGTGCCTGGCGGCG
CAGGAACAGGATCTGGCCATCCAGCTCGCGGCTGTTCTGGCAGTCGGCAGCCAGGCTGTGATGGCGGAAAACCCTGTTTC
GCGTGGGCTGTTTGCACGGCTGCCTAAGGGCGTACAATCGCGCGTCCGCATTGTGTCTGACTGGACTTCGCCGGAGCCCG
CGTTCGACGCGGTGATCCATCATGGCGATTCCGACCAGTTGCGCACGGTGTGCGAGCAGGTCGCAGCGCGGCCGGGGCCG
ATCATCGGCGTGCAGGGCCTCGCGCAAGGTGAGCCGAATATCGCTCTTGAACGTTTGCTGATCGAGCGTTCGCTGTCGGT
CAACACGGCGGCGGCCGGCGGCAACGCCAGCCTGATGACGATCGGCTGA

Upstream 100 bases:

>100_bases
CGCGCCAGCCCAGAGGTTGCGCAGGTCGGGCCCCACTGGCGCTCGCGTCCCACGCGGGCCACATCGACCCGCAGCCTTGT
GTCTTACGGAGAAAGCTCGC

Downstream 100 bases:

>100_bases
GCCGGCACGGACAGAGTTTGTTTGACGTGCGCATGTGCGGCGGCGATCCTGCCGCCATGCGCATCCATAGGGGAGGAGCG
CCCAGACGGCGTTCCCGAAG

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1322; Mature: 1321

Protein sequence:

>1322_residues
MATTTLGVKLDDASRDRLKRVAQSIDRTPHWLIKQAIFTYLEQIERGHLPHEAMAGGAGEADGADGAEMSHADGAPQPFL
EFAQSIQPQSVLRAAITSAYRRPETDCVPVLLEQARLPQQQAEAAIKMAKKLATALREQKVGTGREGLVQGLIQEFSLSS
QEGVALMCLAEALLRIPDKPTRDALIRDKISGANWQSHLGQSPSLFVNAATWGLLLTGKLVATHTESGLSKALTRIIGKG
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEAQGFRYSYDMLGEAAMTEEDAQRYLASYEQAIHAIGQASRGRG
IYEGPGISIKLSALHPRYSRAQHERVINELYERLKSLTLLARQYDIGINIDAEEADRLEISLDLLERLCFEPELAGWNGI
GFVVQGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYVACARKLLSVPDA
IYPQFATHNAHTLSAIYQIAGHSYYPGQYEFQCLHGMGEPLYDQVVGPIADGKFNRPCRIYAPVGTHETLLAYLVRRLLE
NGANTSFVNRIADDTISLDELVADPVAVVETMHRDEGTLGLPHPKIPSPRGLYGKSRANSAGIDLANEHRLASLSSALLA
GTSERVVADPMLGTEVPRAADAITTPVLNPADHRDVVGQVTEASQADVDAALQAAANAAPIWQATPPDVRASALERAADL
MEAQMQSLMGIIMREAGKTFSNAIAEVREAVDFLRYYAAEVRRSFDNETHRPLGPVVCISPWNFPLAIFTGQVAAALAAG
NTVLAKPAEQTPLIAAAAVRILREAGVPAGAVQLLPGRGETVGAALVGDARVKGVMFTGSTEVARILQRNIAGRLDAAGR
PIPLIAETGGQNAMIVDSSALAEQVVGDVVNSAFDSAGQRCSALRVLCLQEDVADRVLAMLKGAMNELTMANPDRLSTDV
GPVIDEEARGNIVRHIDAMRAKGRRVHQADPNAPQGASCRHGTFVPPTLIELDSIDELKREVFGPVLHVVRFPRAALDTM
IGQINGTNYGLTMGIHTRIDETIAQIVQHAEVGNLYVNRNIVGAVVGVQPFGGEALSGTGPKAGGPLYLHRLLSVCPQDA
VVRSVRHAEASGNPPAAPERPVAAQALKDWAKTEMPEVAAACDRFAEASAAGISVTLRGPTGERNTYSLLPRHHVLCLAA
QEQDLAIQLAAVLAVGSQAVMAENPVSRGLFARLPKGVQSRVRIVSDWTSPEPAFDAVIHHGDSDQLRTVCEQVAARPGP
IIGVQGLAQGEPNIALERLLIERSLSVNTAAAGGNASLMTIG

Sequences:

>Translated_1322_residues
MATTTLGVKLDDASRDRLKRVAQSIDRTPHWLIKQAIFTYLEQIERGHLPHEAMAGGAGEADGADGAEMSHADGAPQPFL
EFAQSIQPQSVLRAAITSAYRRPETDCVPVLLEQARLPQQQAEAAIKMAKKLATALREQKVGTGREGLVQGLIQEFSLSS
QEGVALMCLAEALLRIPDKPTRDALIRDKISGANWQSHLGQSPSLFVNAATWGLLLTGKLVATHTESGLSKALTRIIGKG
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEAQGFRYSYDMLGEAAMTEEDAQRYLASYEQAIHAIGQASRGRG
IYEGPGISIKLSALHPRYSRAQHERVINELYERLKSLTLLARQYDIGINIDAEEADRLEISLDLLERLCFEPELAGWNGI
GFVVQGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYVACARKLLSVPDA
IYPQFATHNAHTLSAIYQIAGHSYYPGQYEFQCLHGMGEPLYDQVVGPIADGKFNRPCRIYAPVGTHETLLAYLVRRLLE
NGANTSFVNRIADDTISLDELVADPVAVVETMHRDEGTLGLPHPKIPSPRGLYGKSRANSAGIDLANEHRLASLSSALLA
GTSERVVADPMLGTEVPRAADAITTPVLNPADHRDVVGQVTEASQADVDAALQAAANAAPIWQATPPDVRASALERAADL
MEAQMQSLMGIIMREAGKTFSNAIAEVREAVDFLRYYAAEVRRSFDNETHRPLGPVVCISPWNFPLAIFTGQVAAALAAG
NTVLAKPAEQTPLIAAAAVRILREAGVPAGAVQLLPGRGETVGAALVGDARVKGVMFTGSTEVARILQRNIAGRLDAAGR
PIPLIAETGGQNAMIVDSSALAEQVVGDVVNSAFDSAGQRCSALRVLCLQEDVADRVLAMLKGAMNELTMANPDRLSTDV
GPVIDEEARGNIVRHIDAMRAKGRRVHQADPNAPQGASCRHGTFVPPTLIELDSIDELKREVFGPVLHVVRFPRAALDTM
IGQINGTNYGLTMGIHTRIDETIAQIVQHAEVGNLYVNRNIVGAVVGVQPFGGEALSGTGPKAGGPLYLHRLLSVCPQDA
VVRSVRHAEASGNPPAAPERPVAAQALKDWAKTEMPEVAAACDRFAEASAAGISVTLRGPTGERNTYSLLPRHHVLCLAA
QEQDLAIQLAAVLAVGSQAVMAENPVSRGLFARLPKGVQSRVRIVSDWTSPEPAFDAVIHHGDSDQLRTVCEQVAARPGP
IIGVQGLAQGEPNIALERLLIERSLSVNTAAAGGNASLMTIG
>Mature_1321_residues
ATTTLGVKLDDASRDRLKRVAQSIDRTPHWLIKQAIFTYLEQIERGHLPHEAMAGGAGEADGADGAEMSHADGAPQPFLE
FAQSIQPQSVLRAAITSAYRRPETDCVPVLLEQARLPQQQAEAAIKMAKKLATALREQKVGTGREGLVQGLIQEFSLSSQ
EGVALMCLAEALLRIPDKPTRDALIRDKISGANWQSHLGQSPSLFVNAATWGLLLTGKLVATHTESGLSKALTRIIGKGG
EPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEAQGFRYSYDMLGEAAMTEEDAQRYLASYEQAIHAIGQASRGRGI
YEGPGISIKLSALHPRYSRAQHERVINELYERLKSLTLLARQYDIGINIDAEEADRLEISLDLLERLCFEPELAGWNGIG
FVVQGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYVACARKLLSVPDAI
YPQFATHNAHTLSAIYQIAGHSYYPGQYEFQCLHGMGEPLYDQVVGPIADGKFNRPCRIYAPVGTHETLLAYLVRRLLEN
GANTSFVNRIADDTISLDELVADPVAVVETMHRDEGTLGLPHPKIPSPRGLYGKSRANSAGIDLANEHRLASLSSALLAG
TSERVVADPMLGTEVPRAADAITTPVLNPADHRDVVGQVTEASQADVDAALQAAANAAPIWQATPPDVRASALERAADLM
EAQMQSLMGIIMREAGKTFSNAIAEVREAVDFLRYYAAEVRRSFDNETHRPLGPVVCISPWNFPLAIFTGQVAAALAAGN
TVLAKPAEQTPLIAAAAVRILREAGVPAGAVQLLPGRGETVGAALVGDARVKGVMFTGSTEVARILQRNIAGRLDAAGRP
IPLIAETGGQNAMIVDSSALAEQVVGDVVNSAFDSAGQRCSALRVLCLQEDVADRVLAMLKGAMNELTMANPDRLSTDVG
PVIDEEARGNIVRHIDAMRAKGRRVHQADPNAPQGASCRHGTFVPPTLIELDSIDELKREVFGPVLHVVRFPRAALDTMI
GQINGTNYGLTMGIHTRIDETIAQIVQHAEVGNLYVNRNIVGAVVGVQPFGGEALSGTGPKAGGPLYLHRLLSVCPQDAV
VRSVRHAEASGNPPAAPERPVAAQALKDWAKTEMPEVAAACDRFAEASAAGISVTLRGPTGERNTYSLLPRHHVLCLAAQ
EQDLAIQLAAVLAVGSQAVMAENPVSRGLFARLPKGVQSRVRIVSDWTSPEPAFDAVIHHGDSDQLRTVCEQVAARPGPI
IGVQGLAQGEPNIALERLLIERSLSVNTAAAGGNASLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=460, Percent_Identity=32.6086956521739, Blast_Score=204, Evalue=5e-52,
Organism=Homo sapiens, GI25777724, Length=516, Percent_Identity=29.6511627906977, Blast_Score=194, Evalue=5e-49,
Organism=Homo sapiens, GI25777732, Length=472, Percent_Identity=30.0847457627119, Blast_Score=194, Evalue=6e-49,
Organism=Homo sapiens, GI25777730, Length=504, Percent_Identity=30.7539682539683, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI25777736, Length=470, Percent_Identity=31.2765957446809, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI25777734, Length=470, Percent_Identity=31.2765957446809, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI153266822, Length=458, Percent_Identity=30.3493449781659, Blast_Score=187, Evalue=5e-47,
Organism=Homo sapiens, GI238859541, Length=470, Percent_Identity=31.2765957446809, Blast_Score=187, Evalue=5e-47,
Organism=Homo sapiens, GI25777728, Length=417, Percent_Identity=29.9760191846523, Blast_Score=171, Evalue=6e-42,
Organism=Homo sapiens, GI4507229, Length=495, Percent_Identity=30.5050505050505, Blast_Score=165, Evalue=4e-40,
Organism=Homo sapiens, GI21614513, Length=475, Percent_Identity=28.4210526315789, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI25777721, Length=508, Percent_Identity=29.7244094488189, Blast_Score=156, Evalue=2e-37,
Organism=Homo sapiens, GI12007648, Length=445, Percent_Identity=27.6404494382022, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI238814322, Length=421, Percent_Identity=26.1282660332542, Blast_Score=146, Evalue=2e-34,
Organism=Homo sapiens, GI310128093, Length=466, Percent_Identity=27.8969957081545, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI188035924, Length=466, Percent_Identity=28.3261802575107, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI115387104, Length=503, Percent_Identity=26.2425447316103, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI310128103, Length=466, Percent_Identity=28.3261802575107, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI25777726, Length=516, Percent_Identity=26.7441860465116, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI11095441, Length=424, Percent_Identity=27.5943396226415, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI25952152, Length=443, Percent_Identity=27.5395033860045, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI310128091, Length=466, Percent_Identity=27.6824034334764, Blast_Score=121, Evalue=4e-27,
Organism=Homo sapiens, GI310128087, Length=287, Percent_Identity=30.6620209059233, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI71773324, Length=387, Percent_Identity=25.5813953488372, Blast_Score=101, Evalue=4e-21,
Organism=Homo sapiens, GI4502043, Length=413, Percent_Identity=24.455205811138, Blast_Score=99, Evalue=4e-20,
Organism=Homo sapiens, GI238814371, Length=413, Percent_Identity=24.455205811138, Blast_Score=99, Evalue=4e-20,
Organism=Homo sapiens, GI206597441, Length=452, Percent_Identity=24.1150442477876, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI206597439, Length=452, Percent_Identity=24.1150442477876, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI22907049, Length=452, Percent_Identity=24.1150442477876, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI73695881, Length=332, Percent_Identity=25, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI73695879, Length=332, Percent_Identity=25, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI310128089, Length=332, Percent_Identity=27.710843373494, Blast_Score=89, Evalue=4e-17,
Organism=Homo sapiens, GI310128099, Length=223, Percent_Identity=30.4932735426009, Blast_Score=88, Evalue=5e-17,
Organism=Homo sapiens, GI310128101, Length=223, Percent_Identity=30.4932735426009, Blast_Score=88, Evalue=5e-17,
Organism=Homo sapiens, GI310128095, Length=316, Percent_Identity=27.8481012658228, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI73466520, Length=339, Percent_Identity=23.3038348082596, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI4557303, Length=338, Percent_Identity=23.3727810650888, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI301500698, Length=442, Percent_Identity=22.8506787330317, Blast_Score=78, Evalue=7e-14,
Organism=Homo sapiens, GI310128097, Length=260, Percent_Identity=28.0769230769231, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI223972651, Length=429, Percent_Identity=26.5734265734266, Blast_Score=69, Evalue=4e-11,
Organism=Escherichia coli, GI1787250, Length=1331, Percent_Identity=71.6754320060105, Blast_Score=1880, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=448, Percent_Identity=31.9196428571429, Blast_Score=186, Evalue=6e-48,
Organism=Escherichia coli, GI1787684, Length=464, Percent_Identity=31.4655172413793, Blast_Score=172, Evalue=1e-43,
Organism=Escherichia coli, GI1788042, Length=439, Percent_Identity=32.1184510250569, Blast_Score=172, Evalue=2e-43,
Organism=Escherichia coli, GI1787715, Length=450, Percent_Identity=31.1111111111111, Blast_Score=163, Evalue=6e-41,
Organism=Escherichia coli, GI1786504, Length=464, Percent_Identity=28.6637931034483, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI87081896, Length=478, Percent_Identity=28.6610878661088, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI87082295, Length=493, Percent_Identity=27.789046653144, Blast_Score=151, Evalue=3e-37,
Organism=Escherichia coli, GI1787558, Length=491, Percent_Identity=28.5132382892057, Blast_Score=150, Evalue=5e-37,
Organism=Escherichia coli, GI87081926, Length=430, Percent_Identity=26.5116279069767, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI1787653, Length=268, Percent_Identity=26.1194029850746, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534447, Length=492, Percent_Identity=30.8943089430894, Blast_Score=186, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI25144435, Length=472, Percent_Identity=30.9322033898305, Blast_Score=185, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17562198, Length=475, Percent_Identity=30.1052631578947, Blast_Score=181, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI115534176, Length=458, Percent_Identity=30.5676855895196, Blast_Score=172, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI32564736, Length=410, Percent_Identity=30.9756097560976, Blast_Score=164, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI133930964, Length=468, Percent_Identity=27.5641025641026, Blast_Score=162, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI115532534, Length=388, Percent_Identity=30.1546391752577, Blast_Score=158, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71986308, Length=426, Percent_Identity=28.6384976525822, Blast_Score=150, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI32564151, Length=442, Percent_Identity=28.2805429864253, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25143874, Length=507, Percent_Identity=26.0355029585799, Blast_Score=140, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17551164, Length=473, Percent_Identity=25.5813953488372, Blast_Score=140, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI25143876, Length=507, Percent_Identity=25.8382642998028, Blast_Score=139, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17534119, Length=457, Percent_Identity=25.8205689277899, Blast_Score=134, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71995606, Length=450, Percent_Identity=26.2222222222222, Blast_Score=123, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71995613, Length=407, Percent_Identity=26.2899262899263, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71990744, Length=322, Percent_Identity=28.8819875776398, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI25146391, Length=415, Percent_Identity=22.4096385542169, Blast_Score=96, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=415, Percent_Identity=22.4096385542169, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25146394, Length=415, Percent_Identity=22.4096385542169, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=330, Percent_Identity=25.1515151515152, Blast_Score=90, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320917, Length=460, Percent_Identity=31.5217391304348, Blast_Score=197, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6325196, Length=478, Percent_Identity=30.1255230125523, Blast_Score=192, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6321826, Length=485, Percent_Identity=31.5463917525773, Blast_Score=188, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6324950, Length=454, Percent_Identity=28.4140969162996, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6323821, Length=481, Percent_Identity=29.7297297297297, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6323822, Length=480, Percent_Identity=28.5416666666667, Blast_Score=169, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6319478, Length=464, Percent_Identity=29.0948275862069, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6321828, Length=519, Percent_Identity=23.8921001926782, Blast_Score=105, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6323757, Length=326, Percent_Identity=26.3803680981595, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20129399, Length=474, Percent_Identity=30.168776371308, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281362580, Length=490, Percent_Identity=29.7959183673469, Blast_Score=184, Evalue=3e-46,
Organism=Drosophila melanogaster, GI62472918, Length=490, Percent_Identity=29.7959183673469, Blast_Score=184, Evalue=3e-46,
Organism=Drosophila melanogaster, GI62472926, Length=490, Percent_Identity=29.7959183673469, Blast_Score=184, Evalue=3e-46,
Organism=Drosophila melanogaster, GI62472936, Length=490, Percent_Identity=29.7959183673469, Blast_Score=184, Evalue=3e-46,
Organism=Drosophila melanogaster, GI21356737, Length=490, Percent_Identity=29.7959183673469, Blast_Score=184, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24650465, Length=474, Percent_Identity=28.2700421940928, Blast_Score=183, Evalue=7e-46,
Organism=Drosophila melanogaster, GI24668425, Length=466, Percent_Identity=29.3991416309013, Blast_Score=176, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24668417, Length=466, Percent_Identity=29.3991416309013, Blast_Score=176, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24668413, Length=466, Percent_Identity=29.3991416309013, Blast_Score=176, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24585660, Length=495, Percent_Identity=27.0707070707071, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI28571806, Length=512, Percent_Identity=28.125, Blast_Score=156, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28571802, Length=512, Percent_Identity=28.125, Blast_Score=156, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28571800, Length=512, Percent_Identity=28.125, Blast_Score=156, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28571798, Length=476, Percent_Identity=27.9411764705882, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28571796, Length=476, Percent_Identity=27.9411764705882, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28571794, Length=476, Percent_Identity=27.9411764705882, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24666674, Length=453, Percent_Identity=29.5805739514349, Blast_Score=146, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28574525, Length=474, Percent_Identity=26.7932489451477, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24638878, Length=427, Percent_Identity=27.4004683840749, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24638876, Length=427, Percent_Identity=27.4004683840749, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281360299, Length=352, Percent_Identity=27.8409090909091, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281360297, Length=352, Percent_Identity=27.8409090909091, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281360295, Length=352, Percent_Identity=27.8409090909091, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24586250, Length=352, Percent_Identity=27.8409090909091, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281360301, Length=352, Percent_Identity=27.8409090909091, Blast_Score=95, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45552499, Length=352, Percent_Identity=26.4204545454545, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360303, Length=352, Percent_Identity=26.4204545454545, Blast_Score=91, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 142324; Mature: 142193

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00024 HEMOPEXIN ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTTLGVKLDDASRDRLKRVAQSIDRTPHWLIKQAIFTYLEQIERGHLPHEAMAGGAGE
CCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCC
ADGADGAEMSHADGAPQPFLEFAQSIQPQSVLRAAITSAYRRPETDCVPVLLEQARLPQQ
CCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHH
QAEAAIKMAKKLATALREQKVGTGREGLVQGLIQEFSLSSQEGVALMCLAEALLRIPDKP
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
TRDALIRDKISGANWQSHLGQSPSLFVNAATWGLLLTGKLVATHTESGLSKALTRIIGKG
CHHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCC
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEAQGFRYSYDMLGEAAMTEEDAQR
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHH
YLASYEQAIHAIGQASRGRGIYEGPGISIKLSALHPRYSRAQHERVINELYERLKSLTLL
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARQYDIGINIDAEEADRLEISLDLLERLCFEPELAGWNGIGFVVQGYQKRCPFVIDYLID
HHHHCCCCCCCCCCCCHHEEEHHHHHHHHCCCCCCCCCCCHHHHCCHHHCCCHHHHHHHH
LARRSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYVACARKLLSVPDA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHH
IYPQFATHNAHTLSAIYQIAGHSYYPGQYEFQCLHGMGEPLYDQVVGPIADGKFNRPCRI
HCCCHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCCEEE
YAPVGTHETLLAYLVRRLLENGANTSFVNRIADDTISLDELVADPVAVVETMHRDEGTLG
EECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCHHHHHHHHHCCCCCCC
LPHPKIPSPRGLYGKSRANSAGIDLANEHRLASLSSALLAGTSERVVADPMLGTEVPRAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHH
DAITTPVLNPADHRDVVGQVTEASQADVDAALQAAANAAPIWQATPPDVRASALERAADL
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
MEAQMQSLMGIIMREAGKTFSNAIAEVREAVDFLRYYAAEVRRSFDNETHRPLGPVVCIS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEC
PWNFPLAIFTGQVAAALAAGNTVLAKPAEQTPLIAAAAVRILREAGVPAGAVQLLPGRGE
CCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCC
TVGAALVGDARVKGVMFTGSTEVARILQRNIAGRLDAAGRPIPLIAETGGQNAMIVDSSA
EECCEEECCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEHHH
LAEQVVGDVVNSAFDSAGQRCSALRVLCLQEDVADRVLAMLKGAMNELTMANPDRLSTDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GPVIDEEARGNIVRHIDAMRAKGRRVHQADPNAPQGASCRHGTFVPPTLIELDSIDELKR
CCCCCCHHCCHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCHHHECCCHHHHHH
EVFGPVLHVVRFPRAALDTMIGQINGTNYGLTMGIHTRIDETIAQIVQHAEVGNLYVNRN
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEECCC
IVGAVVGVQPFGGEALSGTGPKAGGPLYLHRLLSVCPQDAVVRSVRHAEASGNPPAAPER
EEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCC
PVAAQALKDWAKTEMPEVAAACDRFAEASAAGISVTLRGPTGERNTYSLLPRHHVLCLAA
CHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEECCCCEEEEEEC
QEQDLAIQLAAVLAVGSQAVMAENPVSRGLFARLPKGVQSRVRIVSDWTSPEPAFDAVIH
CCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHC
HGDSDQLRTVCEQVAARPGPIIGVQGLAQGEPNIALERLLIERSLSVNTAAAGGNASLMT
CCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCEEEE
IG
EC
>Mature Secondary Structure 
ATTTLGVKLDDASRDRLKRVAQSIDRTPHWLIKQAIFTYLEQIERGHLPHEAMAGGAGE
CCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCC
ADGADGAEMSHADGAPQPFLEFAQSIQPQSVLRAAITSAYRRPETDCVPVLLEQARLPQQ
CCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHH
QAEAAIKMAKKLATALREQKVGTGREGLVQGLIQEFSLSSQEGVALMCLAEALLRIPDKP
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
TRDALIRDKISGANWQSHLGQSPSLFVNAATWGLLLTGKLVATHTESGLSKALTRIIGKG
CHHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCC
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEAQGFRYSYDMLGEAAMTEEDAQR
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHH
YLASYEQAIHAIGQASRGRGIYEGPGISIKLSALHPRYSRAQHERVINELYERLKSLTLL
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARQYDIGINIDAEEADRLEISLDLLERLCFEPELAGWNGIGFVVQGYQKRCPFVIDYLID
HHHHCCCCCCCCCCCCHHEEEHHHHHHHHCCCCCCCCCCCHHHHCCHHHCCCHHHHHHHH
LARRSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYVACARKLLSVPDA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHH
IYPQFATHNAHTLSAIYQIAGHSYYPGQYEFQCLHGMGEPLYDQVVGPIADGKFNRPCRI
HCCCHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCCEEE
YAPVGTHETLLAYLVRRLLENGANTSFVNRIADDTISLDELVADPVAVVETMHRDEGTLG
EECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCHHHHHHHHHCCCCCCC
LPHPKIPSPRGLYGKSRANSAGIDLANEHRLASLSSALLAGTSERVVADPMLGTEVPRAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHH
DAITTPVLNPADHRDVVGQVTEASQADVDAALQAAANAAPIWQATPPDVRASALERAADL
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
MEAQMQSLMGIIMREAGKTFSNAIAEVREAVDFLRYYAAEVRRSFDNETHRPLGPVVCIS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEC
PWNFPLAIFTGQVAAALAAGNTVLAKPAEQTPLIAAAAVRILREAGVPAGAVQLLPGRGE
CCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCC
TVGAALVGDARVKGVMFTGSTEVARILQRNIAGRLDAAGRPIPLIAETGGQNAMIVDSSA
EECCEEECCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEHHH
LAEQVVGDVVNSAFDSAGQRCSALRVLCLQEDVADRVLAMLKGAMNELTMANPDRLSTDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GPVIDEEARGNIVRHIDAMRAKGRRVHQADPNAPQGASCRHGTFVPPTLIELDSIDELKR
CCCCCCHHCCHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCHHHECCCHHHHHH
EVFGPVLHVVRFPRAALDTMIGQINGTNYGLTMGIHTRIDETIAQIVQHAEVGNLYVNRN
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEECCC
IVGAVVGVQPFGGEALSGTGPKAGGPLYLHRLLSVCPQDAVVRSVRHAEASGNPPAAPER
EEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCC
PVAAQALKDWAKTEMPEVAAACDRFAEASAAGISVTLRGPTGERNTYSLLPRHHVLCLAA
CHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEECCCCEEEEEEC
QEQDLAIQLAAVLAVGSQAVMAENPVSRGLFARLPKGVQSRVRIVSDWTSPEPAFDAVIH
CCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHC
HGDSDQLRTVCEQVAARPGPIIGVQGLAQGEPNIALERLLIERSLSVNTAAAGGNASLMT
CCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCEEEE
IG
EC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]