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The map label for this gene is htpG [H]

Identifier: 73542028

GI number: 73542028

Start: 2582202

End: 2584103

Strand: Reverse

Name: htpG [H]

Synonym: Reut_A2342

Alternate gene names: 73542028

Gene position: 2584103-2582202 (Counterclockwise)

Preceding gene: 73542029

Following gene: 73542027

Centisome position: 67.89

GC content: 63.3

Gene sequence:

>1902_bases
ATGTCCGCACCGCACGAAACGATGAGCTTCCAGGCGGAAGTGAAGCAACTGCTGCACCTGATGATCCACTCGCTGTACAG
CAACAAGGAAATTTTCCTGCGCGAGCTGGTATCGAATGCTTCGGACGCCACTGACAAGCTGCGCTTCGAGGCGATCGCGA
ATCCCTCCCTGCTCGAGAACGACGCCGACCTGGCCATCCGCATCGAGGCAGACACCGCTGCCCGCACGCTGAAGATCACC
GACAACGGCATCGGCATGAGCCGCGACGAGGCCATCCGCAACCTCGGCACCATCGCCCGTTCAGGTACCAAGGAATTTTT
CCAGCAGCTTTCCGGCGACCAGCAGAAGGACGCCGCGCTGATCGGCCAGTTCGGCGTCGGCTTTTACTCTGCCTTTATCG
TGGCCGACAAGGTCACCGTCGAGACCCGCCGCGCGGGCGTGGCCGCCGACGAAGCCGTGCGCTGGGAAAGCACCGGCGAC
GGCGAGTTCACCGTCGACGCCATCACGCGCGCCGAGCGCGGCACCACCATCACGCTGCACATGCGCGAAGGCGAGGACGA
TTTTCTGTCGGCCTGGCGCCTGAAGAGCATCATCCAGAAGTACTCGGACCACATCTCGCTGCCGATCCGCATGCCCAAGG
AAGTGTGGGATGCCGACACCAGCGCCTACAAGCGTACCGACGAGTGGGAGAGCGTCAACCAGGCCAGCGCGCTGTGGACG
CGTCCGAAGTCGGACATTACCGACGAGCAGTACATCGCGTTCTACCAGCACATCGCGCACGACAATGAAGCGCCGCTGTC
CTGGACGCACAACCGCGTCGAAGGCCGCAGCGAATACACGCAGCTGCTGTACATCCCGGCACGCGCGCCATTCGACCTGT
GGGACCGCAACCACAAGCACGGACTCAAGCTCTACGTGAAGCGCGTCTTCATCATGGACGACGCCGAGCAGTTGTTGCCG
TCGTACCTGCGCTGGGTCAAGGGCGTGATCGATTCGGCTGACCTGCCGCTGAACGTCTCGCGCGAATTGCTGCAGGAAAG
CCGCGACGTCAAGGCGATCCGCGAAGGCAGCACCAAGCGCGTGCTGTCGATGCTCGAATCGCTGGCCGACAGCGAGGAAG
AAGCCGAGCGCGCCAAGTACACGACCTTCTGGCAGCAGTTCGGCCAGGCACTCAAGGAAGGGCTGGGCGAAGACAACGCG
AATCAGGAACGTATCGCCAAGCTGCTGCGCTTTGCCTCGACGCAGAATGACAACGCCGAGCAGAGCGTATCGCTGGCTGC
GTACGTCGGCCGCATGAAGGAAGGCCAGGACAAGATCTACTACGTCACCGCCGACACCTGGGCCGCTGCAAAGAACAGCC
CGCACCTCGAAGTGTTCCGCAAGAAGGGCATCGAAGTCCTGCTGCTGACCGACCGCGTCGACGAATGGATGCTGTCGTTC
CTGCGCGAGTTCGACGGCAAGGAGCTGGTCTCCGTGGCCCGCGGCGACCTGGACCTCGGCAGCCTCGCTGACGAAGCCGA
AAAGGCAGAGCAGGAAAAGGCCGAAACCGAATGGAAGGACGTGGTCGCCCGCGCCAAGACCGTGCTCGAAGGCAAGGCCA
AGGACGTGCGCGTGACGCTGCGCCTGACCGCATCGGCATCGTGCCTGGTCTCGGACGAAGGCGATATGAGCGGCTACCTG
CAGCGCCTGCTGAAGCAGGCCGGCCAGAAAGCGCCGGACGCCCAGCCGATCCTGGAATTGAACCCCGAGCACGCGCTGGT
GAAGAAGCTGCGCGACCTGCCGGAAGGGGACGGCTTCAATGACCGCCTGCTGGTGCTGTTCGACCAGGCACTGCTCGCGG
AAGGCGGTATGCTGGATGATCCCGCCGCTTACGTGCAGCGTGTGAACAAGCTGCTGGCCTGA

Upstream 100 bases:

>100_bases
AGCGGGGTCTTGAAATCCGCCGGTGCCGGCCCTATTTCGGGAGGCATTGGCGACGCGCCAGACCCCATTCCCTGATTTTC
CGGATTCGAAGAGGAGAACC

Downstream 100 bases:

>100_bases
ACATAGGCGTGAAGAGAAGGGCCGGGCGACCGGCCCTTTTTTGCTTCTGGCCTGCGTGAAGGAGAAGGATACAACTGAAG
TCGATTGACGATGCTGAAGC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MSAPHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDATDKLRFEAIANPSLLENDADLAIRIEADTAARTLKIT
DNGIGMSRDEAIRNLGTIARSGTKEFFQQLSGDQQKDAALIGQFGVGFYSAFIVADKVTVETRRAGVAADEAVRWESTGD
GEFTVDAITRAERGTTITLHMREGEDDFLSAWRLKSIIQKYSDHISLPIRMPKEVWDADTSAYKRTDEWESVNQASALWT
RPKSDITDEQYIAFYQHIAHDNEAPLSWTHNRVEGRSEYTQLLYIPARAPFDLWDRNHKHGLKLYVKRVFIMDDAEQLLP
SYLRWVKGVIDSADLPLNVSRELLQESRDVKAIREGSTKRVLSMLESLADSEEEAERAKYTTFWQQFGQALKEGLGEDNA
NQERIAKLLRFASTQNDNAEQSVSLAAYVGRMKEGQDKIYYVTADTWAAAKNSPHLEVFRKKGIEVLLLTDRVDEWMLSF
LREFDGKELVSVARGDLDLGSLADEAEKAEQEKAETEWKDVVARAKTVLEGKAKDVRVTLRLTASASCLVSDEGDMSGYL
QRLLKQAGQKAPDAQPILELNPEHALVKKLRDLPEGDGFNDRLLVLFDQALLAEGGMLDDPAAYVQRVNKLLA

Sequences:

>Translated_633_residues
MSAPHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDATDKLRFEAIANPSLLENDADLAIRIEADTAARTLKIT
DNGIGMSRDEAIRNLGTIARSGTKEFFQQLSGDQQKDAALIGQFGVGFYSAFIVADKVTVETRRAGVAADEAVRWESTGD
GEFTVDAITRAERGTTITLHMREGEDDFLSAWRLKSIIQKYSDHISLPIRMPKEVWDADTSAYKRTDEWESVNQASALWT
RPKSDITDEQYIAFYQHIAHDNEAPLSWTHNRVEGRSEYTQLLYIPARAPFDLWDRNHKHGLKLYVKRVFIMDDAEQLLP
SYLRWVKGVIDSADLPLNVSRELLQESRDVKAIREGSTKRVLSMLESLADSEEEAERAKYTTFWQQFGQALKEGLGEDNA
NQERIAKLLRFASTQNDNAEQSVSLAAYVGRMKEGQDKIYYVTADTWAAAKNSPHLEVFRKKGIEVLLLTDRVDEWMLSF
LREFDGKELVSVARGDLDLGSLADEAEKAEQEKAETEWKDVVARAKTVLEGKAKDVRVTLRLTASASCLVSDEGDMSGYL
QRLLKQAGQKAPDAQPILELNPEHALVKKLRDLPEGDGFNDRLLVLFDQALLAEGGMLDDPAAYVQRVNKLLA
>Mature_632_residues
SAPHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDATDKLRFEAIANPSLLENDADLAIRIEADTAARTLKITD
NGIGMSRDEAIRNLGTIARSGTKEFFQQLSGDQQKDAALIGQFGVGFYSAFIVADKVTVETRRAGVAADEAVRWESTGDG
EFTVDAITRAERGTTITLHMREGEDDFLSAWRLKSIIQKYSDHISLPIRMPKEVWDADTSAYKRTDEWESVNQASALWTR
PKSDITDEQYIAFYQHIAHDNEAPLSWTHNRVEGRSEYTQLLYIPARAPFDLWDRNHKHGLKLYVKRVFIMDDAEQLLPS
YLRWVKGVIDSADLPLNVSRELLQESRDVKAIREGSTKRVLSMLESLADSEEEAERAKYTTFWQQFGQALKEGLGEDNAN
QERIAKLLRFASTQNDNAEQSVSLAAYVGRMKEGQDKIYYVTADTWAAAKNSPHLEVFRKKGIEVLLLTDRVDEWMLSFL
REFDGKELVSVARGDLDLGSLADEAEKAEQEKAETEWKDVVARAKTVLEGKAKDVRVTLRLTASASCLVSDEGDMSGYLQ
RLLKQAGQKAPDAQPILELNPEHALVKKLRDLPEGDGFNDRLLVLFDQALLAEGGMLDDPAAYVQRVNKLLA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=691, Percent_Identity=37.7713458755427, Blast_Score=427, Evalue=1e-119,
Organism=Homo sapiens, GI155722983, Length=637, Percent_Identity=35.6357927786499, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI154146191, Length=414, Percent_Identity=37.43961352657, Blast_Score=282, Evalue=8e-76,
Organism=Homo sapiens, GI153792590, Length=414, Percent_Identity=37.43961352657, Blast_Score=279, Evalue=5e-75,
Organism=Homo sapiens, GI20149594, Length=414, Percent_Identity=37.1980676328502, Blast_Score=276, Evalue=3e-74,
Organism=Escherichia coli, GI1786679, Length=630, Percent_Identity=60, Blast_Score=768, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=677, Percent_Identity=38.2570162481536, Blast_Score=469, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI17542208, Length=683, Percent_Identity=37.7745241581259, Blast_Score=410, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI115535205, Length=652, Percent_Identity=31.5950920245399, Blast_Score=298, Evalue=8e-81,
Organism=Caenorhabditis elegans, GI115535167, Length=441, Percent_Identity=33.5600907029478, Blast_Score=242, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6323840, Length=681, Percent_Identity=37.7386196769457, Blast_Score=449, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6325016, Length=685, Percent_Identity=37.5182481751825, Blast_Score=448, Evalue=1e-126,
Organism=Drosophila melanogaster, GI17647529, Length=693, Percent_Identity=37.8066378066378, Blast_Score=462, Evalue=1e-130,
Organism=Drosophila melanogaster, GI21357739, Length=684, Percent_Identity=35.9649122807018, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24586016, Length=655, Percent_Identity=34.3511450381679, Blast_Score=349, Evalue=4e-96,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71267; Mature: 71136

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDATDKLRFEAIANPSLLEN
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHCCC
DADLAIRIEADTAARTLKITDNGIGMSRDEAIRNLGTIARSGTKEFFQQLSGDQQKDAAL
CCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
IGQFGVGFYSAFIVADKVTVETRRAGVAADEAVRWESTGDGEFTVDAITRAERGTTITLH
HHHHHHHHHHHHHHHHHEEEHHHHCCCCHHHCEEECCCCCCCEEEHHHHHCCCCCEEEEE
MREGEDDFLSAWRLKSIIQKYSDHISLPIRMPKEVWDADTSAYKRTDEWESVNQASALWT
EECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHCCHHHHHHHHHHHHHC
RPKSDITDEQYIAFYQHIAHDNEAPLSWTHNRVEGRSEYTQLLYIPARAPFDLWDRNHKH
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCHHHHCCCCCC
GLKLYVKRVFIMDDAEQLLPSYLRWVKGVIDSADLPLNVSRELLQESRDVKAIREGSTKR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
VLSMLESLADSEEEAERAKYTTFWQQFGQALKEGLGEDNANQERIAKLLRFASTQNDNAE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHH
QSVSLAAYVGRMKEGQDKIYYVTADTWAAAKNSPHLEVFRKKGIEVLLLTDRVDEWMLSF
HHHHHHHHHHHHCCCCCEEEEEEECCHHCCCCCCHHHHHHHCCCEEEEEECHHHHHHHHH
LREFDGKELVSVARGDLDLGSLADEAEKAEQEKAETEWKDVVARAKTVLEGKAKDVRVTL
HHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
RLTASASCLVSDEGDMSGYLQRLLKQAGQKAPDAQPILELNPEHALVKKLRDLPEGDGFN
EEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCC
DRLLVLFDQALLAEGGMLDDPAAYVQRVNKLLA
CCEEEEEHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SAPHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDATDKLRFEAIANPSLLEN
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHCCC
DADLAIRIEADTAARTLKITDNGIGMSRDEAIRNLGTIARSGTKEFFQQLSGDQQKDAAL
CCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
IGQFGVGFYSAFIVADKVTVETRRAGVAADEAVRWESTGDGEFTVDAITRAERGTTITLH
HHHHHHHHHHHHHHHHHEEEHHHHCCCCHHHCEEECCCCCCCEEEHHHHHCCCCCEEEEE
MREGEDDFLSAWRLKSIIQKYSDHISLPIRMPKEVWDADTSAYKRTDEWESVNQASALWT
EECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHCCHHHHHHHHHHHHHC
RPKSDITDEQYIAFYQHIAHDNEAPLSWTHNRVEGRSEYTQLLYIPARAPFDLWDRNHKH
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCHHHHCCCCCC
GLKLYVKRVFIMDDAEQLLPSYLRWVKGVIDSADLPLNVSRELLQESRDVKAIREGSTKR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
VLSMLESLADSEEEAERAKYTTFWQQFGQALKEGLGEDNANQERIAKLLRFASTQNDNAE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHH
QSVSLAAYVGRMKEGQDKIYYVTADTWAAAKNSPHLEVFRKKGIEVLLLTDRVDEWMLSF
HHHHHHHHHHHHCCCCCEEEEEEECCHHCCCCCCHHHHHHHCCCEEEEEECHHHHHHHHH
LREFDGKELVSVARGDLDLGSLADEAEKAEQEKAETEWKDVVARAKTVLEGKAKDVRVTL
HHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
RLTASASCLVSDEGDMSGYLQRLLKQAGQKAPDAQPILELNPEHALVKKLRDLPEGDGFN
EEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCC
DRLLVLFDQALLAEGGMLDDPAAYVQRVNKLLA
CCEEEEEHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA