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The map label for this gene is hflX [H]

Identifier: 73541768

GI number: 73541768

Start: 2286917

End: 2288161

Strand: Reverse

Name: hflX [H]

Synonym: Reut_A2080

Alternate gene names: 73541768

Gene position: 2288161-2286917 (Counterclockwise)

Preceding gene: 73541769

Following gene: 73541767

Centisome position: 60.11

GC content: 64.98

Gene sequence:

>1245_bases
TTGGATCCCAGAGCTACCTCCAACACCGAACCGTCGCGTGCCATTCTCGTTGGCGTGGATTTCGGCAAGCACGATTTCCA
GGAAAGCCTGAGCGAGCTTGCCTTGCTGACCACCACTGCCGGCTCCATGCCGGTGCATACGCTGACCGGCAAACGTTCGC
GCCCGGACCCGGCGCTGTTCATCGGCTCGGGCAAGGCCGAAGAGCTGCGGGAAGCGGCGGACGCGCTGGATGCCGATATC
GTGGTGTTCAACCATGCCCTGAGCCCGGCACAGCAACGTAACCTCGAACGCTTCTTGCAGCGCCATGTGATTGACCGTAC
CGGCCTGATCCTGGACATCTTCGCGCAGCGTGCCCAGAGCCACGTGGGCAAGGTGCAGGTGGAGCTGGCGCAGGTTCAAT
ACCAGGCGTCGCGGCTCGTCCGTGCGTGGAGCCACCTGGAGCGGCAGAAGGGCGGTATCGGCATGCGGGGCGGCCCGGGC
GAACGCCAGCTCGAACTGGACCGACGCATGCTGGATGACCGGGCCAAGCGGCTGAAGTCCGACCTTGCCCGGCTGCAGCG
GCAGCACCGCACGCAGCGGCGCGCCCGCGCGCGCAACGACACCTTGAGCATTTCGCTGGTGGGCTATACCAATGCGGGCA
AGTCGACGCTGTTCAATGCGTTGACCAAGGCCGGCGCGTACGCGGCCAACCAGCTTTTCGCGACGCTTGATACGACCTCG
CGCCGGATGTTCCTGGACGGGCTTGGCAATGTGGTGCTGTCGGACACGGTCGGCTTCATCCGTGACCTGCCGACGCAACT
GGTCGAGGCGTTCCGCGCAACGCTGGACGAAACTGTGCATGCCGACCTGCTGTTGCATGTCGTCGATGCGTCTAGCCCCG
TGCGGCATGAGCAGATCGAACAGGTCAACCGTGTGCTGGCGGAAATCGAAGCGTCCGGCATCCCGCAGATCATCGTGATG
AACAAGATCGATGCTGCGCCGGAACTGCTCGAGCAGGGCGTGCGTGTGGAGCGTGACGAGGAGGGCGTTCCGACGCGGGT
GTTCCTCAGTGCGCGCGAGGGCATTGGCCTGGATGCGTTGCGGCAGTCGATCGTCGAGGTCGCGCAATGGCTTGCGAGCC
GTCCGCCCGAGCCGGCACCGTTTGATCCACGGCTGGCGGAGCAGGGGCCGCGCTTGGACGACGAGGAGTTTGAATGGGAT
GAGCGCGAGGGTCACGATGATCGCGAAGATCGCCGCCCGTCCTGA

Upstream 100 bases:

>100_bases
CCGCTCCCGTCCCGCTGAACCGGGACACGTCCGGCCTTCCGTCCGGCTCATATCCGGACATCTCCCCAAACCGTCTCACT
TCGCGCGTAGCGCCCCCCGC

Downstream 100 bases:

>100_bases
TCCTTTTCGGCGAGATTCGCGGCCGGATTACGCGCATTGGCCAAAAGTGGCGCAGATGACTGCTAGAATCCCCCTGTTAC
AAACTTCCCGGACCCGTGCA

Product: small GTP-binding protein domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MDPRATSNTEPSRAILVGVDFGKHDFQESLSELALLTTTAGSMPVHTLTGKRSRPDPALFIGSGKAEELREAADALDADI
VVFNHALSPAQQRNLERFLQRHVIDRTGLILDIFAQRAQSHVGKVQVELAQVQYQASRLVRAWSHLERQKGGIGMRGGPG
ERQLELDRRMLDDRAKRLKSDLARLQRQHRTQRRARARNDTLSISLVGYTNAGKSTLFNALTKAGAYAANQLFATLDTTS
RRMFLDGLGNVVLSDTVGFIRDLPTQLVEAFRATLDETVHADLLLHVVDASSPVRHEQIEQVNRVLAEIEASGIPQIIVM
NKIDAAPELLEQGVRVERDEEGVPTRVFLSAREGIGLDALRQSIVEVAQWLASRPPEPAPFDPRLAEQGPRLDDEEFEWD
EREGHDDREDRRPS

Sequences:

>Translated_414_residues
MDPRATSNTEPSRAILVGVDFGKHDFQESLSELALLTTTAGSMPVHTLTGKRSRPDPALFIGSGKAEELREAADALDADI
VVFNHALSPAQQRNLERFLQRHVIDRTGLILDIFAQRAQSHVGKVQVELAQVQYQASRLVRAWSHLERQKGGIGMRGGPG
ERQLELDRRMLDDRAKRLKSDLARLQRQHRTQRRARARNDTLSISLVGYTNAGKSTLFNALTKAGAYAANQLFATLDTTS
RRMFLDGLGNVVLSDTVGFIRDLPTQLVEAFRATLDETVHADLLLHVVDASSPVRHEQIEQVNRVLAEIEASGIPQIIVM
NKIDAAPELLEQGVRVERDEEGVPTRVFLSAREGIGLDALRQSIVEVAQWLASRPPEPAPFDPRLAEQGPRLDDEEFEWD
EREGHDDREDRRPS
>Mature_414_residues
MDPRATSNTEPSRAILVGVDFGKHDFQESLSELALLTTTAGSMPVHTLTGKRSRPDPALFIGSGKAEELREAADALDADI
VVFNHALSPAQQRNLERFLQRHVIDRTGLILDIFAQRAQSHVGKVQVELAQVQYQASRLVRAWSHLERQKGGIGMRGGPG
ERQLELDRRMLDDRAKRLKSDLARLQRQHRTQRRARARNDTLSISLVGYTNAGKSTLFNALTKAGAYAANQLFATLDTTS
RRMFLDGLGNVVLSDTVGFIRDLPTQLVEAFRATLDETVHADLLLHVVDASSPVRHEQIEQVNRVLAEIEASGIPQIIVM
NKIDAAPELLEQGVRVERDEEGVPTRVFLSAREGIGLDALRQSIVEVAQWLASRPPEPAPFDPRLAEQGPRLDDEEFEWD
EREGHDDREDRRPS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=202, Percent_Identity=38.1188118811881, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI310133116, Length=198, Percent_Identity=38.3838383838384, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI310124269, Length=177, Percent_Identity=38.9830508474576, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124267, Length=177, Percent_Identity=38.9830508474576, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124171, Length=177, Percent_Identity=38.9830508474576, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124169, Length=177, Percent_Identity=38.9830508474576, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI1790615, Length=406, Percent_Identity=51.2315270935961, Blast_Score=370, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17561038, Length=321, Percent_Identity=28.9719626168224, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24650079, Length=321, Percent_Identity=34.2679127725857, Blast_Score=121, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 46194; Mature: 46194

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPRATSNTEPSRAILVGVDFGKHDFQESLSELALLTTTAGSMPVHTLTGKRSRPDPALF
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEE
IGSGKAEELREAADALDADIVVFNHALSPAQQRNLERFLQRHVIDRTGLILDIFAQRAQS
ECCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HVGKVQVELAQVQYQASRLVRAWSHLERQKGGIGMRGGPGERQLELDRRMLDDRAKRLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DLARLQRQHRTQRRARARNDTLSISLVGYTNAGKSTLFNALTKAGAYAANQLFATLDTTS
HHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
RRMFLDGLGNVVLSDTVGFIRDLPTQLVEAFRATLDETVHADLLLHVVDASSPVRHEQIE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QVNRVLAEIEASGIPQIIVMNKIDAAPELLEQGVRVERDEEGVPTRVFLSAREGIGLDAL
HHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHH
RQSIVEVAQWLASRPPEPAPFDPRLAEQGPRLDDEEFEWDEREGHDDREDRRPS
HHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDPRATSNTEPSRAILVGVDFGKHDFQESLSELALLTTTAGSMPVHTLTGKRSRPDPALF
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEE
IGSGKAEELREAADALDADIVVFNHALSPAQQRNLERFLQRHVIDRTGLILDIFAQRAQS
ECCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HVGKVQVELAQVQYQASRLVRAWSHLERQKGGIGMRGGPGERQLELDRRMLDDRAKRLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DLARLQRQHRTQRRARARNDTLSISLVGYTNAGKSTLFNALTKAGAYAANQLFATLDTTS
HHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
RRMFLDGLGNVVLSDTVGFIRDLPTQLVEAFRATLDETVHADLLLHVVDASSPVRHEQIE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QVNRVLAEIEASGIPQIIVMNKIDAAPELLEQGVRVERDEEGVPTRVFLSAREGIGLDAL
HHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHH
RQSIVEVAQWLASRPPEPAPFDPRLAEQGPRLDDEEFEWDEREGHDDREDRRPS
HHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]